ITMI931741A0 - Procedimento per la preparazione della diacereina - Google Patents
Procedimento per la preparazione della diacereinaInfo
- Publication number
- ITMI931741A0 ITMI931741A0 IT93MI1741A ITMI931741A ITMI931741A0 IT MI931741 A0 ITMI931741 A0 IT MI931741A0 IT 93MI1741 A IT93MI1741 A IT 93MI1741A IT MI931741 A ITMI931741 A IT MI931741A IT MI931741 A0 ITMI931741 A0 IT MI931741A0
- Authority
- IT
- Italy
- Prior art keywords
- diacerein
- procedure
- preparation
- Prior art date
Links
- TYNLGDBUJLVSMA-UHFFFAOYSA-N 4,5-diacetyloxy-9,10-dioxo-2-anthracenecarboxylic acid Chemical compound O=C1C2=CC(C(O)=O)=CC(OC(C)=O)=C2C(=O)C2=C1C=CC=C2OC(=O)C TYNLGDBUJLVSMA-UHFFFAOYSA-N 0.000 title 1
- 229960004590 diacerein Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/28—Preparation of carboxylic acid esters by modifying the hydroxylic moiety of the ester, such modification not being an introduction of an ester group
- C07C67/293—Preparation of carboxylic acid esters by modifying the hydroxylic moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/22—Ortho- or ortho- and peri-condensed systems containing three rings containing only six-membered rings
- C07C2603/24—Anthracenes; Hydrogenated anthracenes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Rheumatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Cephalosporin Compounds (AREA)
- Compounds Of Unknown Constitution (AREA)
Priority Applications (12)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT93MI001741A IT1264545B1 (it) | 1993-07-30 | 1993-07-30 | Procedimento per la preparazione della diacereina |
EP94110551A EP0636602B1 (en) | 1993-07-30 | 1994-07-07 | A process for the preparation of diacerein |
AT94110551T ATE165335T1 (de) | 1993-07-30 | 1994-07-07 | Verfahren zur herstellung von diacerein |
DK94110551T DK0636602T3 (da) | 1993-07-30 | 1994-07-07 | Fremgangsmåde til fremstilling af diacerein |
ES94110551T ES2115814T3 (es) | 1993-07-30 | 1994-07-07 | Procedimiento para la preparacion de diacerein. |
DE69409722T DE69409722T2 (de) | 1993-07-30 | 1994-07-07 | Verfahren zur Herstellung von Diacerein |
JP19269394A JP3850458B2 (ja) | 1993-07-30 | 1994-07-26 | ジアセラインの製造プロセス |
CZ199590A CZ286702B6 (en) | 1993-07-30 | 1995-01-12 | Process for preparing diacerein |
SK44-95A SK281699B6 (sk) | 1993-07-30 | 1995-01-12 | Spôsob prípravy diacereínu |
HU9500188A HU221980B1 (hu) | 1993-07-30 | 1995-01-23 | Eljárás diacerein előállítására és új acilezett aloin intermedier |
US08/376,722 US5670695A (en) | 1993-07-30 | 1995-01-23 | Process for the preparation of diacerein |
CA002141247A CA2141247C (en) | 1993-07-30 | 1995-01-27 | Process for the preparation of diacerein |
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT93MI001741A IT1264545B1 (it) | 1993-07-30 | 1993-07-30 | Procedimento per la preparazione della diacereina |
CZ199590A CZ286702B6 (en) | 1993-07-30 | 1995-01-12 | Process for preparing diacerein |
SK44-95A SK281699B6 (sk) | 1993-07-30 | 1995-01-12 | Spôsob prípravy diacereínu |
HU9500188A HU221980B1 (hu) | 1993-07-30 | 1995-01-23 | Eljárás diacerein előállítására és új acilezett aloin intermedier |
US08/376,722 US5670695A (en) | 1993-07-30 | 1995-01-23 | Process for the preparation of diacerein |
CA002141247A CA2141247C (en) | 1993-07-30 | 1995-01-27 | Process for the preparation of diacerein |
Publications (3)
Publication Number | Publication Date |
---|---|
ITMI931741A0 true ITMI931741A0 (it) | 1993-07-30 |
ITMI931741A1 ITMI931741A1 (it) | 1995-01-30 |
IT1264545B1 IT1264545B1 (it) | 1996-10-02 |
Family
ID=27543486
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT93MI001741A IT1264545B1 (it) | 1993-07-30 | 1993-07-30 | Procedimento per la preparazione della diacereina |
Country Status (12)
Country | Link |
---|---|
US (1) | US5670695A (it) |
EP (1) | EP0636602B1 (it) |
JP (1) | JP3850458B2 (it) |
AT (1) | ATE165335T1 (it) |
CA (1) | CA2141247C (it) |
CZ (1) | CZ286702B6 (it) |
DE (1) | DE69409722T2 (it) |
DK (1) | DK0636602T3 (it) |
ES (1) | ES2115814T3 (it) |
HU (1) | HU221980B1 (it) |
IT (1) | IT1264545B1 (it) |
SK (1) | SK281699B6 (it) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH689279A5 (fr) * | 1995-02-07 | 1999-01-29 | Steba Beheer Bv | Procédé de purification de la diacétylrhéine. |
IT1283771B1 (it) * | 1996-07-31 | 1998-04-30 | Medidom Lab | Procedimento per la preparazione di derivati della reina |
IT1283772B1 (it) * | 1996-07-31 | 1998-04-30 | Medidom Lab | Procedimento per la preparazione di reina e diacereina |
IT1292132B1 (it) * | 1997-06-11 | 1999-01-25 | Synteco S R L | Procedimento per la preparazione di diacereina |
IT1297038B1 (it) * | 1997-12-30 | 1999-08-03 | Medidom Lab | Procedimento per la preparazione di reina e suoi diacilderivati |
US6451771B1 (en) | 1999-02-12 | 2002-09-17 | Nutramax Laboratories, Inc. | Use of anabolic agents anti-catabolic agents and antioxidant agents for protection treatment and repair of connective tissues in humans and animals |
US20070141181A1 (en) | 1998-02-13 | 2007-06-21 | Nutramax Laboratories, Inc. | Use of anabolic agents, anti-catabolic agents, antioxidant agents, and analgesics for protection, treatment and repair of connective tissues in humans and animals |
US6797289B2 (en) * | 1998-02-13 | 2004-09-28 | Nutramax Laboratories, Inc. | Use of anabolic agents, anti-catabolic agents, antioxidant agents, and analgesics for protection, treatment and repair of connective tissues in humans and animals |
IT1312309B1 (it) * | 1999-05-07 | 2002-04-15 | Synteco Spa | Procedimento per la purificazione di diacereina |
AR026801A1 (es) | 2000-01-12 | 2003-02-26 | Medidom Lab | Sustancias para uso en el tratamiento de la psoriasis |
IT1318574B1 (it) * | 2000-06-13 | 2003-08-27 | Synteco Spa | Procedimento per la purificazione di diacereina. |
ITMI20022535A1 (it) * | 2002-11-29 | 2004-05-30 | Synteco Spa | Procedimento per la purificazione della diacereina. |
EP2060562A1 (en) | 2007-11-16 | 2009-05-20 | Laboratoire Medidom S.A. | Dioxoanthracene sulphonate derivatives |
WO2009106908A1 (en) | 2008-02-29 | 2009-09-03 | Laboratoire Medidom S.A. | Process for preparing rhein |
WO2009106909A1 (en) * | 2008-02-29 | 2009-09-03 | Laboratoire Medidom S.A. | Process for the purification of diacerein |
WO2011030350A1 (en) | 2009-09-08 | 2011-03-17 | Lupin Limited | Eco-friendly method for catalytic aerial oxidation of aloe-emodin to rheinal |
CN101696164A (zh) * | 2009-10-19 | 2010-04-21 | 黄再新 | 一步法用芦荟甙合成双醋瑞因粗品的方法 |
ITTO20110120A1 (it) | 2011-02-11 | 2012-08-12 | Icrom Spa | Un nuovo processo di purificazione per derivati antrachinonici |
CN104774150B (zh) * | 2014-01-14 | 2017-04-12 | 北京万生药业有限责任公司 | 一种双醋瑞因晶体及其制备方法 |
CN112279767B (zh) * | 2020-10-29 | 2023-02-03 | 陕西嘉禾生物科技股份有限公司 | 一种双醋瑞因的制备方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA761627B (en) * | 1976-03-16 | 1978-01-25 | C Friedmann | Improvements in or relating to the treatment of arthritis |
IT1189097B (it) * | 1986-05-02 | 1988-01-28 | Proter Spa | Sali di diacetilreina e loro impiego terapeutico nel trattamento dell'artrosi |
US5393898A (en) * | 1991-06-25 | 1995-02-28 | Madaus Ag | Method of preparing diacetyl rhein |
DE4120989C2 (de) * | 1991-06-25 | 1995-07-27 | Madaus Ag | Verfahren zur Herstellung von Diacetylrhein |
-
1993
- 1993-07-30 IT IT93MI001741A patent/IT1264545B1/it active IP Right Grant
-
1994
- 1994-07-07 DE DE69409722T patent/DE69409722T2/de not_active Expired - Lifetime
- 1994-07-07 EP EP94110551A patent/EP0636602B1/en not_active Expired - Lifetime
- 1994-07-07 ES ES94110551T patent/ES2115814T3/es not_active Expired - Lifetime
- 1994-07-07 DK DK94110551T patent/DK0636602T3/da active
- 1994-07-07 AT AT94110551T patent/ATE165335T1/de active
- 1994-07-26 JP JP19269394A patent/JP3850458B2/ja not_active Expired - Lifetime
-
1995
- 1995-01-12 SK SK44-95A patent/SK281699B6/sk not_active IP Right Cessation
- 1995-01-12 CZ CZ199590A patent/CZ286702B6/cs not_active IP Right Cessation
- 1995-01-23 HU HU9500188A patent/HU221980B1/hu active IP Right Grant
- 1995-01-23 US US08/376,722 patent/US5670695A/en not_active Expired - Lifetime
- 1995-01-27 CA CA002141247A patent/CA2141247C/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0636602A1 (en) | 1995-02-01 |
CA2141247C (en) | 2004-08-31 |
DK0636602T3 (da) | 1999-01-11 |
EP0636602B1 (en) | 1998-04-22 |
US5670695A (en) | 1997-09-23 |
ES2115814T3 (es) | 1998-07-01 |
DE69409722D1 (de) | 1998-05-28 |
HUT73498A (en) | 1996-08-28 |
ATE165335T1 (de) | 1998-05-15 |
SK281699B6 (sk) | 2001-07-10 |
JPH0753462A (ja) | 1995-02-28 |
SK4495A3 (en) | 1996-08-07 |
DE69409722T2 (de) | 1998-08-13 |
CZ286702B6 (en) | 2000-06-14 |
CA2141247A1 (en) | 1996-07-28 |
JP3850458B2 (ja) | 2006-11-29 |
CZ9095A3 (en) | 1996-07-17 |
ITMI931741A1 (it) | 1995-01-30 |
IT1264545B1 (it) | 1996-10-02 |
HU221980B1 (hu) | 2003-03-28 |
HU9500188D0 (en) | 1995-03-28 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ITMI931741A0 (it) | Procedimento per la preparazione della diacereina | |
NO923340D0 (no) | Fremgangsmaate ved fremstilling av olefiner | |
ITMI920569A0 (it) | Procedimento per la fabbricazione di tastiere | |
ITMI912025A0 (it) | Procedimento per la preparazione di demetilepipodofillotossina-beta-dglucosidi | |
ITMI931680A0 (it) | Procedimento per la preparazione di alcansolfonammidi | |
IT1292132B1 (it) | Procedimento per la preparazione di diacereina | |
FI952134A (fi) | Menetelmä alkyykibentseenin valmistamiseksi | |
IT8822524A0 (it) | Procedimento di preparazione di 6-ossopenicillanati | |
IT1267078B1 (it) | Apparecchiatura per la preparazione di soluzioni | |
IT8821611A0 (it) | Procedimento di preparazione della levo- e destro-dropropizina | |
ITMI922432A0 (it) | Procedimento per la preparazione di diltiazem | |
ITMI922181A0 (it) | Procedimento per la preparazione di perfluoro-2-metil-4-metossipentano | |
IT9022506A0 (it) | Procedimento per la preparazione di un intermedio | |
ITMI930520A0 (it) | Procedimento per la preparazione di dipendenti solfonati | |
ITMI930340A1 (it) | Procedimento per la preparazione di 5-oxo-2-pirrolidoncarbossilato di piridossina | |
ITMI932694A0 (it) | Procedimento per la preparazione di 2-idrossi-1-4-noftochinoni | |
ITMI921783A0 (it) | Procedimento per la preparazione di dinitrodifenilmetani | |
ITMI932324A0 (it) | Procedimento per la purificazione della 9-(2-idrossi) etossimetilguanina | |
ITMI910706A0 (it) | Procedimento di preparazione della timopentina | |
ITMI930983A0 (it) | Procedimento per la preparazione del (+)-3-idrossi-17-metilmorfinano | |
ITMI931800A0 (it) | Uso della 4 -desossi-4-iododoxorubicina per il trattamento della alamiloidosi | |
ITRM930608A0 (it) | Procedimento per la preparazione della 9-(2-idrossi)etossimetil- guanina. | |
SV1993000010A (es) | Preparacion de nuevas sulfonamidocarboxamidas | |
ITMI911369A0 (it) | Procedimento per la preparazione di l-gamma glicerilfosforilcolina | |
ITMI911070A0 (it) | Procedimento per la preparazione di l-alfa-glicerofosforilcolina |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
0001 | Granted | ||
TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19970730 |