DK0630428T3 - Fremgangsmåde til fremstilling af taxanderivater - Google Patents
Fremgangsmåde til fremstilling af taxanderivaterInfo
- Publication number
- DK0630428T3 DK0630428T3 DK93918756.3T DK93918756T DK0630428T3 DK 0630428 T3 DK0630428 T3 DK 0630428T3 DK 93918756 T DK93918756 T DK 93918756T DK 0630428 T3 DK0630428 T3 DK 0630428T3
- Authority
- DK
- Denmark
- Prior art keywords
- radical
- general formula
- taxane derivatives
- preparation
- trichloro
- Prior art date
Links
- DKPFODGZWDEEBT-QFIAKTPHSA-N taxane Chemical class C([C@]1(C)CCC[C@@H](C)[C@H]1C1)C[C@H]2[C@H](C)CC[C@@H]1C2(C)C DKPFODGZWDEEBT-QFIAKTPHSA-N 0.000 title abstract 2
- -1 heterocyclyl radical Chemical class 0.000 abstract 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- TUCNEACPLKLKNU-UHFFFAOYSA-N acetyl Chemical compound C[C]=O TUCNEACPLKLKNU-UHFFFAOYSA-N 0.000 abstract 1
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- 230000000259 anti-tumor effect Effects 0.000 abstract 1
- 150000005840 aryl radicals Chemical class 0.000 abstract 1
- 150000001602 bicycloalkyls Chemical group 0.000 abstract 1
- 125000000392 cycloalkenyl group Chemical group 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- LEVJVKGPFAQPOI-UHFFFAOYSA-N phenylmethanone Chemical compound O=[C]C1=CC=CC=C1 LEVJVKGPFAQPOI-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
- C25B—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
- C25B3/00—Electrolytic production of organic compounds
- C25B3/20—Processes
- C25B3/25—Reduction
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
- C25B—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
- C25B11/00—Electrodes; Manufacture thereof not otherwise provided for
- C25B11/04—Electrodes; Manufacture thereof not otherwise provided for characterised by the material
- C25B11/042—Electrodes formed of a single material
- C25B11/043—Carbon, e.g. diamond or graphene
-
- C—CHEMISTRY; METALLURGY
- C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
- C25B—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
- C25B11/00—Electrodes; Manufacture thereof not otherwise provided for
- C25B11/04—Electrodes; Manufacture thereof not otherwise provided for characterised by the material
- C25B11/042—Electrodes formed of a single material
- C25B11/046—Alloys
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Electrochemistry (AREA)
- Materials Engineering (AREA)
- Metallurgy (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Electrolytic Production Of Non-Metals, Compounds, Apparatuses Therefor (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Epoxy Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9203000A FR2688518B1 (fr) | 1992-03-13 | 1992-03-13 | Procede de preparation de derives du taxane. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0630428T3 true DK0630428T3 (da) | 1995-12-27 |
Family
ID=9427641
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK93918756.3T DK0630428T3 (da) | 1992-03-13 | 1993-03-11 | Fremgangsmåde til fremstilling af taxanderivater |
Country Status (21)
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6794523B2 (en) | 1991-09-23 | 2004-09-21 | Florida State University | Taxanes having t-butoxycarbonyl substituted side-chains and pharmaceutical compositions containing them |
| ES2211879T3 (es) * | 1993-03-22 | 2004-07-16 | Florida State University | Taxanos que no tienen un grupo oxo en c9 y composiciones farmaceuticas que las contienen. |
| US5760251A (en) * | 1995-08-11 | 1998-06-02 | Sepracor, Inc. | Taxol process and compounds |
| US6103698A (en) * | 1997-03-13 | 2000-08-15 | Basf Aktiengesellschaft | Dolastatin-15 derivatives in combination with taxanes |
| JP4338527B2 (ja) | 2002-04-05 | 2009-10-07 | サンタリス ファーマ アー／エス | ＨＩＦ−１α発現を調節するオリゴマー化合物 |
| US7713738B2 (en) | 2003-02-10 | 2010-05-11 | Enzon Pharmaceuticals, Inc. | Oligomeric compounds for the modulation of survivin expression |
| JP4642775B2 (ja) | 2003-12-23 | 2011-03-02 | サンタリス ファーマ アー／エス | Ｂｃｌ−２のモデュレーションのためのオリゴマー化合物 |
| US9447138B2 (en) | 2004-11-09 | 2016-09-20 | Roche Innovation Center Copenhagen A/S | Potent LNA oligonucleotides for the inhibition of HIF-1a expression |
| MX2007005557A (es) | 2004-11-09 | 2008-02-15 | Santaris Pharma As | Oligonucleotidos lna y el tratamiento de cancer. |
| MX2007005558A (es) | 2004-11-09 | 2008-01-31 | Santaris Pharma As | Oligonucleotidos de lna potentes para la inhibicion dela expresion de hif-1a. |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS60187689A (ja) * | 1984-03-06 | 1985-09-25 | Otsuka Chem Co Ltd | ３−エキソメチレンセフアム誘導体の製造法 |
| FR2601675B1 (fr) * | 1986-07-17 | 1988-09-23 | Rhone Poulenc Sante | Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent |
| FR2629818B1 (fr) * | 1988-04-06 | 1990-11-16 | Centre Nat Rech Scient | Procede de preparation du taxol |
| FR2664894A1 (fr) * | 1990-07-19 | 1992-01-24 | Rhone Poulenc Sante | Nouveaux derives de streptogramines et leur preparation. |
-
1992
- 1992-03-13 FR FR9203000A patent/FR2688518B1/fr not_active Expired - Fee Related
-
1993
- 1993-03-11 MX MX9301345A patent/MX9301345A/es unknown
- 1993-03-11 SK SK1084-94A patent/SK108494A3/sk unknown
- 1993-03-11 AU AU37563/93A patent/AU3756393A/en not_active Abandoned
- 1993-03-11 JP JP5515408A patent/JPH07504461A/ja active Pending
- 1993-03-11 AT AT93918756T patent/ATE130053T1/de not_active IP Right Cessation
- 1993-03-11 KR KR1019940703185A patent/KR950700439A/ko not_active Withdrawn
- 1993-03-11 HU HU9402614A patent/HUT68282A/hu unknown
- 1993-03-11 CZ CZ942186A patent/CZ218694A3/cs unknown
- 1993-03-11 ES ES93918756T patent/ES2079982T3/es not_active Expired - Lifetime
- 1993-03-11 WO PCT/FR1993/000243 patent/WO1993018210A1/fr not_active Application Discontinuation
- 1993-03-11 DK DK93918756.3T patent/DK0630428T3/da active
- 1993-03-11 CA CA002117552A patent/CA2117552A1/fr not_active Abandoned
- 1993-03-11 EP EP93918756A patent/EP0630428B1/fr not_active Expired - Lifetime
- 1993-03-11 DE DE69300766T patent/DE69300766T2/de not_active Expired - Fee Related
- 1993-03-12 ZA ZA931800A patent/ZA931800B/xx unknown
- 1993-03-13 TW TW082101872A patent/TW235961B/zh active
-
1994
- 1994-09-12 RU RU94041682/04A patent/RU94041682A/ru unknown
- 1994-09-12 NO NO943371A patent/NO943371L/no unknown
- 1994-09-12 FI FI944190A patent/FI944190A7/fi not_active Application Discontinuation
-
1995
- 1995-11-09 GR GR950401848T patent/GR3018036T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR950700439A (ko) | 1995-01-16 |
| MX9301345A (es) | 1993-09-01 |
| DE69300766D1 (de) | 1995-12-14 |
| WO1993018210A1 (fr) | 1993-09-16 |
| GR3018036T3 (en) | 1996-02-29 |
| HU9402614D0 (en) | 1994-11-28 |
| FI944190A0 (fi) | 1994-09-12 |
| JPH07504461A (ja) | 1995-05-18 |
| FR2688518B1 (fr) | 1994-05-06 |
| DE69300766T2 (de) | 1996-04-18 |
| NO943371D0 (no) | 1994-09-12 |
| EP0630428A1 (fr) | 1994-12-28 |
| AU3756393A (en) | 1993-10-05 |
| FI944190A7 (fi) | 1994-09-12 |
| ZA931800B (en) | 1993-09-30 |
| ES2079982T3 (es) | 1996-01-16 |
| ATE130053T1 (de) | 1995-11-15 |
| HUT68282A (en) | 1995-04-03 |
| SK108494A3 (en) | 1995-02-08 |
| TW235961B (enrdf_load_html_response) | 1994-12-11 |
| CA2117552A1 (fr) | 1993-09-16 |
| RU94041682A (ru) | 1996-07-20 |
| NO943371L (no) | 1994-09-12 |
| EP0630428B1 (fr) | 1995-11-08 |
| FR2688518A1 (fr) | 1993-09-17 |
| CZ218694A3 (en) | 1995-02-15 |
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