DK0630235T3 - Fremgangsmåde til fremstilling af pellets med forsinket frigivelse - Google Patents

Fremgangsmåde til fremstilling af pellets med forsinket frigivelse

Info

Publication number
DK0630235T3
DK0630235T3 DK93908213.7T DK93908213T DK0630235T3 DK 0630235 T3 DK0630235 T3 DK 0630235T3 DK 93908213 T DK93908213 T DK 93908213T DK 0630235 T3 DK0630235 T3 DK 0630235T3
Authority
DK
Denmark
Prior art keywords
pct
binder
release pellets
sec
delayed release
Prior art date
Application number
DK93908213.7T
Other languages
Danish (da)
English (en)
Inventor
Henning G Kristensen
Torben Schaefer
Lars Juul Thomsen
Arne Kristensen
Original Assignee
Pharmacia & Upjohn Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia & Upjohn Ab filed Critical Pharmacia & Upjohn Ab
Application granted granted Critical
Publication of DK0630235T3 publication Critical patent/DK0630235T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1611—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Medicinal Preparation (AREA)
  • Glanulating (AREA)
  • Processing And Handling Of Plastics And Other Materials For Molding In General (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Disintegrating Or Milling (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DK93908213.7T 1992-03-20 1993-03-16 Fremgangsmåde til fremstilling af pellets med forsinket frigivelse DK0630235T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9200858A SE9200858L (sv) 1992-03-20 1992-03-20 Metod för framställning av pellets med fördröjd frisättning

Publications (1)

Publication Number Publication Date
DK0630235T3 true DK0630235T3 (da) 1998-02-02

Family

ID=20385679

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93908213.7T DK0630235T3 (da) 1992-03-20 1993-03-16 Fremgangsmåde til fremstilling af pellets med forsinket frigivelse

Country Status (12)

Country Link
US (1) US5807583A (fr)
EP (1) EP0630235B1 (fr)
JP (1) JPH07505360A (fr)
AT (1) ATE154756T1 (fr)
AU (1) AU675062B2 (fr)
CA (1) CA2132451C (fr)
DE (1) DE69311800T2 (fr)
DK (1) DK0630235T3 (fr)
ES (1) ES2105240T3 (fr)
GR (1) GR3024604T3 (fr)
SE (1) SE9200858L (fr)
WO (1) WO1993018753A1 (fr)

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IL109944A (en) * 1993-07-01 1998-12-06 Euro Celtique Sa Continuous release dosage form containing morphine and a method of preparing such sustained release unit dosage forms
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KR100354702B1 (ko) * 1993-11-23 2002-12-28 유로-셀티크 소시에떼 아노뉨 약학조성물의제조방법및서방형조성물
US6524832B1 (en) * 1994-02-04 2003-02-25 Arch Development Corporation DNA damaging agents in combination with tyrosine kinase inhibitors
EP0672416A1 (fr) * 1994-03-14 1995-09-20 Euro-Celtique S.A. Composition pharmaceutique à base de diamorphine
GB9422154D0 (en) † 1994-11-03 1994-12-21 Euro Celtique Sa Pharmaceutical compositions and method of producing the same
US5827537A (en) * 1995-05-04 1998-10-27 Smithkline Beecham Corporation Pharmaceutical thermal infusion process
GB9519363D0 (en) * 1995-09-22 1995-11-22 Euro Celtique Sa Pharmaceutical formulation
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DE19729487A1 (de) * 1997-07-10 1999-01-14 Dresden Arzneimittel Verfahren zur Herstellung von Wirkstoff-Zubereitungen mit kontrollierter Freisetzung aus einer Matrix
WO1999013864A2 (fr) * 1997-09-19 1999-03-25 Shire Laboratories, Inc. Granule de solution solide
DK173431B1 (da) 1998-03-20 2000-10-23 Gea Farmaceutisk Fabrik As Farmaceutisk formulering omfattende en 2-[[(2-pyridinyl)methyl]sulfinyl]benzimidazol med anti-ulcusaktivitet samt fremgangs
US10179130B2 (en) 1999-10-29 2019-01-15 Purdue Pharma L.P. Controlled release hydrocodone formulations
KR20020059653A (ko) 1999-10-29 2002-07-13 그린 마틴, 브라이언 쥐 테슬리 서방성 하이드로코돈 제형
US6953593B2 (en) * 2000-02-01 2005-10-11 Lipoprotein Technologies, Inc. Sustained-release microencapsulated delivery system
KR100713234B1 (ko) * 2000-10-02 2007-05-02 유에스브이 리미티드 메트포민을 함유하는 지속방출형 약학 조성물 및 이의제조방법
PT1195160E (pt) 2000-10-05 2009-12-07 Usv Ltd Composições farmacêuticas de trimetazidina de libertação sustentada e método para a sua preparação
HU230686B1 (en) 2000-10-30 2017-08-28 Euro Celtique Sa Controlled release hydrocodone compositions
IT1319655B1 (it) 2000-11-15 2003-10-23 Eurand Int Microsfere di enzimi pancreatici con elevata stabilita' e relativometodo di preparazione.
US20110104214A1 (en) 2004-04-15 2011-05-05 Purdue Pharma L.P. Once-a-day oxycodone formulations
US9107804B2 (en) 2002-12-10 2015-08-18 Nortec Development Associates, Inc. Method of preparing biologically active formulations
DE10300325A1 (de) 2003-01-09 2004-07-22 Hexal Ag Granulat mit öliger Substanz, Herstellungsverfahren und Tablette
US20060153915A1 (en) * 2003-01-23 2006-07-13 Amorepacific Corporation Sustained-release preparations and method for producing the same
US8034605B2 (en) * 2003-03-26 2011-10-11 Kyu-Jin Yum Microbial materials for degradation of oils and toxic chemicals
KR100412759B1 (en) * 2003-03-26 2004-01-07 Kyu Jin Yum Microbial preparation for decomposing oils and toxic chemicals
US20090214644A1 (en) * 2003-07-31 2009-08-27 Xanodyne Pharmaceuticals, Inc. Tranexamic acid formulations with reduced adverse effects
US20050025825A1 (en) * 2003-07-31 2005-02-03 Xanodyne Pharmacal, Inc. Tranexamic acid formulations with reduced adverse effects
WO2005019163A2 (fr) 2003-08-20 2005-03-03 Xenoport, Inc. Prodrogues a base de carbamate d'alkyle acyle, procede de synthese et utilisation
EP2371815A1 (fr) 2003-12-30 2011-10-05 XenoPort, Inc. Synthèses de promédicaments à base de carbamate d'acyloxyalkyle et intermédiaires associés
US8022106B2 (en) * 2004-03-04 2011-09-20 Ferring B.V. Tranexamic acid formulations
US20050245614A1 (en) * 2004-03-04 2005-11-03 Xanodyne Pharmaceuticals, Inc. Tranexamic acid formulations
US7947739B2 (en) 2004-03-04 2011-05-24 Ferring B.V. Tranexamic acid formulations
US20090215898A1 (en) * 2004-03-04 2009-08-27 Xanodyne Pharmaceuticals, Inc. Tranexamic acid formulations
US20050244495A1 (en) 2004-03-04 2005-11-03 Xanodyne Pharmaceuticals, Inc. Tranexamic acid formulations
EP1753405A4 (fr) * 2004-06-10 2008-09-17 Glatt Air Tech Inc Preparation pharmaceutique a liberation lente
US9034373B2 (en) * 2006-03-16 2015-05-19 Euro-Celtique S.A. Pharmaceutical spheroids
ES2674681T3 (es) 2007-02-20 2018-07-03 Allergan Pharmaceuticals International Limited Composiciones estables de enzimas digestivas
ES2350029T3 (es) * 2007-03-02 2011-01-17 Farnam Companies, Inc. Pellets de liberación sostenida que comprenden un material tipo cera.
US10087493B2 (en) 2008-03-07 2018-10-02 Aptalis Pharma Canada Ulc Method for detecting infectious parvovirus in pharmaceutical preparations
US20100280117A1 (en) * 2009-04-30 2010-11-04 Xanodyne Pharmaceuticals, Inc. Menorrhagia Instrument and Method for the Treatment of Menstrual Bleeding Disorders
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WO2013090452A1 (fr) * 2011-12-12 2013-06-20 Orbis Biosciences, Inc. Formulations de particules à libération prolongée
WO2015020943A2 (fr) 2013-08-09 2015-02-12 Aptalis Pharma Ltd. Composition d'enzymes digestives appropriée pour une administration entérale
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WO2015193730A1 (fr) 2014-06-19 2015-12-23 Aptalis Pharma Ltd. Procédés d'élimination de contaminants viraux dans des extraits pancréatiques
WO2016174664A1 (fr) 2015-04-29 2016-11-03 Dexcel Pharma Technologies Ltd. Compositions à désintégration par voie orale
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US5008112A (en) * 1985-12-16 1991-04-16 International Minerals & Chem. Corporation Device for the extended delivery of diffusible agents
DE3721721C1 (de) * 1987-07-01 1988-06-09 Hoechst Ag Verfahren zur Umhuellung von Granulaten
JP2681373B2 (ja) * 1988-07-18 1997-11-26 塩野義製薬株式会社 徐放性製剤の製造法
DK161743C (da) * 1989-07-03 1992-02-17 Niro Atomizer As Fremgangsmaade og apparat til agglomerering af et pulverformigt materiale
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US5358560A (en) * 1991-10-04 1994-10-25 Eastman Chemical Company Solid-form additive systems dispersible in aqueous media and method for their preparation

Also Published As

Publication number Publication date
AU675062B2 (en) 1997-01-23
SE9200858D0 (sv) 1992-03-20
DE69311800D1 (de) 1997-07-31
JPH07505360A (ja) 1995-06-15
AU3911193A (en) 1993-10-21
CA2132451A1 (fr) 1993-09-30
ES2105240T3 (es) 1997-10-16
DE69311800T2 (de) 1998-01-08
CA2132451C (fr) 2003-06-10
GR3024604T3 (en) 1997-12-31
WO1993018753A1 (fr) 1993-09-30
ATE154756T1 (de) 1997-07-15
EP0630235A1 (fr) 1994-12-28
SE9200858L (sv) 1993-09-21
US5807583A (en) 1998-09-15
EP0630235B1 (fr) 1997-06-25

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