DK0630235T3 - Fremgangsmåde til fremstilling af pellets med forsinket frigivelse - Google Patents

Fremgangsmåde til fremstilling af pellets med forsinket frigivelse

Info

Publication number
DK0630235T3
DK0630235T3 DK93908213.7T DK93908213T DK0630235T3 DK 0630235 T3 DK0630235 T3 DK 0630235T3 DK 93908213 T DK93908213 T DK 93908213T DK 0630235 T3 DK0630235 T3 DK 0630235T3
Authority
DK
Denmark
Prior art keywords
pct
binder
release pellets
sec
delayed release
Prior art date
Application number
DK93908213.7T
Other languages
Danish (da)
English (en)
Inventor
Henning G Kristensen
Torben Schaefer
Lars Juul Thomsen
Arne Kristensen
Original Assignee
Pharmacia & Upjohn Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia & Upjohn Ab filed Critical Pharmacia & Upjohn Ab
Application granted granted Critical
Publication of DK0630235T3 publication Critical patent/DK0630235T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1611—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Medicinal Preparation (AREA)
  • Processing And Handling Of Plastics And Other Materials For Molding In General (AREA)
  • Glanulating (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Disintegrating Or Milling (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DK93908213.7T 1992-03-20 1993-03-16 Fremgangsmåde til fremstilling af pellets med forsinket frigivelse DK0630235T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9200858A SE9200858L (sv) 1992-03-20 1992-03-20 Metod för framställning av pellets med fördröjd frisättning

Publications (1)

Publication Number Publication Date
DK0630235T3 true DK0630235T3 (da) 1998-02-02

Family

ID=20385679

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93908213.7T DK0630235T3 (da) 1992-03-20 1993-03-16 Fremgangsmåde til fremstilling af pellets med forsinket frigivelse

Country Status (12)

Country Link
US (1) US5807583A (fr)
EP (1) EP0630235B1 (fr)
JP (1) JPH07505360A (fr)
AT (1) ATE154756T1 (fr)
AU (1) AU675062B2 (fr)
CA (1) CA2132451C (fr)
DE (1) DE69311800T2 (fr)
DK (1) DK0630235T3 (fr)
ES (1) ES2105240T3 (fr)
GR (1) GR3024604T3 (fr)
SE (1) SE9200858L (fr)
WO (1) WO1993018753A1 (fr)

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ES2168290T3 (es) * 1993-11-23 2002-06-16 Euro Celtique Sa Metodo para preparar una composicion de liberacion sostenida.
KR100354702B1 (ko) * 1993-11-23 2002-12-28 유로-셀티크 소시에떼 아노뉨 약학조성물의제조방법및서방형조성물
US6524832B1 (en) * 1994-02-04 2003-02-25 Arch Development Corporation DNA damaging agents in combination with tyrosine kinase inhibitors
EP0672416A1 (fr) * 1994-03-14 1995-09-20 Euro-Celtique S.A. Composition pharmaceutique à base de diamorphine
GB9422154D0 (en) † 1994-11-03 1994-12-21 Euro Celtique Sa Pharmaceutical compositions and method of producing the same
US5827537A (en) * 1995-05-04 1998-10-27 Smithkline Beecham Corporation Pharmaceutical thermal infusion process
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DE19729487A1 (de) * 1997-07-10 1999-01-14 Dresden Arzneimittel Verfahren zur Herstellung von Wirkstoff-Zubereitungen mit kontrollierter Freisetzung aus einer Matrix
CA2302275C (fr) * 1997-09-19 2009-12-08 Shire Laboratories, Inc. Granule de solution solide
DK173431B1 (da) 1998-03-20 2000-10-23 Gea Farmaceutisk Fabrik As Farmaceutisk formulering omfattende en 2-[[(2-pyridinyl)methyl]sulfinyl]benzimidazol med anti-ulcusaktivitet samt fremgangs
MXPA02004293A (es) 1999-10-29 2002-10-31 Euro Celtique Sa Formulaciones de hidrocodona de liberacion controlada..
US10179130B2 (en) 1999-10-29 2019-01-15 Purdue Pharma L.P. Controlled release hydrocodone formulations
US6953593B2 (en) * 2000-02-01 2005-10-11 Lipoprotein Technologies, Inc. Sustained-release microencapsulated delivery system
EP1322158B1 (fr) * 2000-10-02 2012-08-08 USV Ltd. Compositions pharmaceutiques a liberation prolongee contenant de la metformine, procedes de production de ces dernieres
PT1195160E (pt) 2000-10-05 2009-12-07 Usv Ltd Composições farmacêuticas de trimetazidina de libertação sustentada e método para a sua preparação
EP1337244A4 (fr) 2000-10-30 2006-01-11 Euro Celtique Sa Preparations d'hydrocodone a liberation lente
IT1319655B1 (it) 2000-11-15 2003-10-23 Eurand Int Microsfere di enzimi pancreatici con elevata stabilita' e relativometodo di preparazione.
US20110104214A1 (en) 2004-04-15 2011-05-05 Purdue Pharma L.P. Once-a-day oxycodone formulations
US9107804B2 (en) 2002-12-10 2015-08-18 Nortec Development Associates, Inc. Method of preparing biologically active formulations
DE10300325A1 (de) 2003-01-09 2004-07-22 Hexal Ag Granulat mit öliger Substanz, Herstellungsverfahren und Tablette
KR100712356B1 (ko) * 2003-01-23 2007-05-02 (주)아모레퍼시픽 서방성 제제 및 그의 제조방법
US8034605B2 (en) * 2003-03-26 2011-10-11 Kyu-Jin Yum Microbial materials for degradation of oils and toxic chemicals
KR100412759B1 (en) * 2003-03-26 2004-01-07 Kyu Jin Yum Microbial preparation for decomposing oils and toxic chemicals
US20050025825A1 (en) * 2003-07-31 2005-02-03 Xanodyne Pharmacal, Inc. Tranexamic acid formulations with reduced adverse effects
US20090214644A1 (en) * 2003-07-31 2009-08-27 Xanodyne Pharmaceuticals, Inc. Tranexamic acid formulations with reduced adverse effects
BRPI0413756A (pt) * 2003-08-20 2006-10-31 Xenoport Inc composto, métodos para tratar ou evitar espasticidade ou um sintoma de espasticidade, doença de refluxo gastro-esofágico, vìcio em droga, vìcio em ou abuso de álcool, ou vìcio em ou abuso de nicotina, e tosse ou êmese em um paciente, e, composição farmacêutica
CN102702065A (zh) * 2003-12-30 2012-10-03 什诺波特有限公司 酰氧基烃基氨基甲酸酯前药及其中间体的合成
US20050244495A1 (en) * 2004-03-04 2005-11-03 Xanodyne Pharmaceuticals, Inc. Tranexamic acid formulations
US20050245614A1 (en) * 2004-03-04 2005-11-03 Xanodyne Pharmaceuticals, Inc. Tranexamic acid formulations
US20090215898A1 (en) * 2004-03-04 2009-08-27 Xanodyne Pharmaceuticals, Inc. Tranexamic acid formulations
US8022106B2 (en) * 2004-03-04 2011-09-20 Ferring B.V. Tranexamic acid formulations
US7947739B2 (en) 2004-03-04 2011-05-24 Ferring B.V. Tranexamic acid formulations
US20070224269A1 (en) * 2004-06-10 2007-09-27 Rubino Orapin P Controlled Release Pharmaceutical Formulation
JP5443768B2 (ja) * 2006-03-16 2014-03-19 ユーロセルティック ソシエテ アノニム 医薬品球状物
PT2079445E (pt) 2007-02-20 2016-02-29 Allergan Pharmaceuticals Internat Ltd Composições de enzimas digestivas estáveis
ATE476176T1 (de) * 2007-03-02 2010-08-15 Farnam Co Inc Wachsähnliches material enthaltende tabletten mit verzögerter freisetzung
WO2009109856A2 (fr) 2008-03-07 2009-09-11 Axcan Pharma Inc. Procédé pour détecter un parvovirus infectieux dans des préparations pharmaceutiques
US20100280117A1 (en) * 2009-04-30 2010-11-04 Xanodyne Pharmaceuticals, Inc. Menorrhagia Instrument and Method for the Treatment of Menstrual Bleeding Disorders
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CA2920844A1 (fr) 2013-08-09 2015-02-12 Allergan Pharmaceuticals International Limited Composition d'enzymes digestives appropriee pour une administration enterale
US11813361B2 (en) 2014-04-04 2023-11-14 Pharmaquest International Center, Llp Disintegrating monolithic modified release tablets containing quadri-layer extended release granules
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EP3288556A4 (fr) 2015-04-29 2018-09-19 Dexcel Pharma Technologies Ltd. Compositions à désintégration par voie orale
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JP2681373B2 (ja) * 1988-07-18 1997-11-26 塩野義製薬株式会社 徐放性製剤の製造法
DK161743C (da) * 1989-07-03 1992-02-17 Niro Atomizer As Fremgangsmaade og apparat til agglomerering af et pulverformigt materiale
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US5358560A (en) * 1991-10-04 1994-10-25 Eastman Chemical Company Solid-form additive systems dispersible in aqueous media and method for their preparation

Also Published As

Publication number Publication date
EP0630235B1 (fr) 1997-06-25
AU3911193A (en) 1993-10-21
ES2105240T3 (es) 1997-10-16
EP0630235A1 (fr) 1994-12-28
US5807583A (en) 1998-09-15
JPH07505360A (ja) 1995-06-15
SE9200858D0 (sv) 1992-03-20
SE9200858L (sv) 1993-09-21
DE69311800T2 (de) 1998-01-08
ATE154756T1 (de) 1997-07-15
CA2132451A1 (fr) 1993-09-30
GR3024604T3 (en) 1997-12-31
WO1993018753A1 (fr) 1993-09-30
AU675062B2 (en) 1997-01-23
CA2132451C (fr) 2003-06-10
DE69311800D1 (de) 1997-07-31

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