ES8203606A1 - Procedimiento para la preparacion de una mezcla de un este- roide anti-inflamatorio y un fluoro-cloro-hidrocarburo para ser utilizado como propulsor - Google Patents

Procedimiento para la preparacion de una mezcla de un este- roide anti-inflamatorio y un fluoro-cloro-hidrocarburo para ser utilizado como propulsor

Info

Publication number
ES8203606A1
ES8203606A1 ES502286A ES502286A ES8203606A1 ES 8203606 A1 ES8203606 A1 ES 8203606A1 ES 502286 A ES502286 A ES 502286A ES 502286 A ES502286 A ES 502286A ES 8203606 A1 ES8203606 A1 ES 8203606A1
Authority
ES
Spain
Prior art keywords
propellant
steroid
particle size
fluoro
chloro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES502286A
Other languages
English (en)
Other versions
ES502286A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Orion Oyj
Original Assignee
Orion Yhtyma Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orion Yhtyma Oy filed Critical Orion Yhtyma Oy
Publication of ES502286A0 publication Critical patent/ES502286A0/es
Publication of ES8203606A1 publication Critical patent/ES8203606A1/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K3/00—Materials not provided for elsewhere
    • C09K3/30—Materials not provided for elsewhere for aerosols

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dispersion Chemistry (AREA)
  • Otolaryngology (AREA)
  • Materials Engineering (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE UNA MEZCLA DE UN ESTEROIDE ANTINFLAMATORIO Y UN FLUORO-CLORO-HIDROCARBURO, QUE TIENE APLICACIONES FARMACOLOGICAS EN FORMA DE AEROSOLES. CONSISTE EN SUSPENDER EL ESTEROIDE A UNA TEMPERATURA ENTRE -40 Y 5GC EN UNA PEQUEÑA CANTIDAD DE UN FLUORO-CLORO-HIDROCARBURO PARA SER UTILIZADO COMO PROPULSOR, ENTRE EL 1 Y 10 POR 100 DE LA CANTIDAD TOTAL DE PROPULSOR UTILIZADA; AGITAD LA MEZCLA AL MENOS DURANTE 24 HORAS, AÑADIENDO LA CANTIDAD NECESARIA DE PROPULSOR DURANTE O DESPUES DE LA AGITACION.
ES502286A 1980-05-19 1981-05-18 Procedimiento para la preparacion de una mezcla de un este- roide anti-inflamatorio y un fluoro-cloro-hidrocarburo para ser utilizado como propulsor Expired ES8203606A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FI801610A FI63672C (fi) 1980-05-19 1980-05-19 Foerfarande foer framstaellning av en blandning av beklometasondipropionat och triklorfluormetan eller diklordifluormetan

Publications (2)

Publication Number Publication Date
ES502286A0 ES502286A0 (es) 1982-04-01
ES8203606A1 true ES8203606A1 (es) 1982-04-01

Family

ID=8513487

Family Applications (1)

Application Number Title Priority Date Filing Date
ES502286A Expired ES8203606A1 (es) 1980-05-19 1981-05-18 Procedimiento para la preparacion de una mezcla de un este- roide anti-inflamatorio y un fluoro-cloro-hidrocarburo para ser utilizado como propulsor

Country Status (21)

Country Link
US (1) US4347236A (es)
JP (1) JPS5716820A (es)
AT (1) AT380791B (es)
BE (1) BE888822A (es)
CA (1) CA1162852A (es)
CH (1) CH647408A5 (es)
CS (1) CS221831B2 (es)
DD (1) DD158856A5 (es)
DE (1) DE3119745A1 (es)
DK (1) DK218481A (es)
ES (1) ES8203606A1 (es)
FI (1) FI63672C (es)
FR (1) FR2482457A1 (es)
GB (1) GB2076422B (es)
HU (1) HU188093B (es)
NL (1) NL8102457A (es)
NO (1) NO155429C (es)
PL (1) PL127872B1 (es)
PT (1) PT72989B (es)
SE (1) SE437766B (es)
SU (1) SU1184428A3 (es)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR890000664B1 (ko) * 1981-10-19 1989-03-22 바리 안소니 뉴우샘 미분된 베클로메타손 디프로피오네이트 일수화물의 제조방법
AU601176B2 (en) * 1986-03-10 1990-09-06 Kurt Burghart Benzodiazepine aerosols
JPH01156916A (ja) * 1987-09-25 1989-06-20 Ss Pharmaceut Co Ltd 肝疾患治療剤
US5658549A (en) * 1991-12-12 1997-08-19 Glaxo Group Limited Aerosol formulations containing propellant 134a and fluticasone propionate
US5653962A (en) * 1991-12-12 1997-08-05 Glaxo Group Limited Aerosol formulations containing P134a and particulate medicaments
US5744123A (en) * 1991-12-12 1998-04-28 Glaxo Group Limited Aerosol formulations containing P134a and particulate medicaments
US5916540A (en) 1994-10-24 1999-06-29 Glaxo Group Limited Aerosol formulations containing P134A and/or P227 and particulate medicament
US5674471A (en) * 1991-12-12 1997-10-07 Glaxo Group Limited Aerosol formulations containing P134a and salbutamol
US5736124A (en) * 1991-12-12 1998-04-07 Glaxo Group Limited Aerosol formulations containing P134a and particulate medicament
IL104068A (en) * 1991-12-12 1998-10-30 Glaxo Group Ltd Pharmaceutical preparations in a spray without surfactant containing 1, 1, 1, 2 tetrafluoroethane or 1,1,2,3,3 petafluor N propane as propellant
CA2421976C (en) * 1991-12-12 2004-04-20 Glaxo Group Limited Medicaments
US7101534B1 (en) 1991-12-18 2006-09-05 3M Innovative Properties Company Suspension aerosol formulations
AU675633B2 (en) * 1991-12-18 1997-02-13 Minnesota Mining And Manufacturing Company Suspension aerosol formulations
US7105152B1 (en) 1991-12-18 2006-09-12 3M Innovative Properties Company Suspension aerosol formulations
GB9202519D0 (en) * 1992-02-06 1992-03-25 Glaxo Group Ltd Medicaments
US5376359A (en) * 1992-07-07 1994-12-27 Glaxo, Inc. Method of stabilizing aerosol formulations
MX9304585A (es) * 1992-07-31 1994-03-31 Glaxo Group Ltd Formulacion farmaceutica en aerosol, lata adecuada para liberar la formulacion e inhalador de dosis dosificada que comprende la lata.
GB0208742D0 (en) 2002-04-17 2002-05-29 Bradford Particle Design Ltd Particulate materials
US7582284B2 (en) 2002-04-17 2009-09-01 Nektar Therapeutics Particulate materials
AU2008214205B2 (en) 2007-02-11 2014-04-24 Map Pharmaceuticals, Inc. Method of therapeutic administration of DHE to enable rapid relief of migraine while minimizing side effect profile
US9394314B2 (en) 2012-12-21 2016-07-19 Map Pharmaceuticals, Inc. 8′-hydroxy-dihydroergotamine compounds and compositions

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE629985A (es) * 1962-11-29
GB1429184A (en) * 1972-04-20 1976-03-24 Allen & Hanburys Ltd Physically anti-inflammatory steroids for use in aerosols
JPS531814A (en) * 1976-06-28 1978-01-10 Toshiba Corp Control unit of induction motor
US4225597A (en) * 1976-10-01 1980-09-30 Schering Corporation Beclomethasone dipropionate-hexane solvate and aerosols prepared therefrom
IT1121513B (it) * 1979-05-28 1986-04-02 Chiesi Farma Spa Processo per la conversione di umo steroide antiinfiammatorio in una forma suscettibile di essere somministarta come aerosol

Also Published As

Publication number Publication date
JPS5716820A (en) 1982-01-28
SU1184428A3 (ru) 1985-10-07
US4347236A (en) 1982-08-31
FR2482457A1 (fr) 1981-11-20
HU188093B (en) 1986-03-28
NL8102457A (nl) 1981-12-16
ES502286A0 (es) 1982-04-01
DD158856A5 (de) 1983-02-09
PL127872B1 (en) 1983-12-31
GB2076422A (en) 1981-12-02
CH647408A5 (de) 1985-01-31
DK218481A (da) 1981-11-20
CA1162852A (en) 1984-02-28
PL231220A1 (es) 1982-01-18
ATA179181A (de) 1985-12-15
CS221831B2 (en) 1983-04-29
NO811686L (no) 1981-11-20
FI63672B (fi) 1983-04-29
NO155429C (no) 1987-04-01
FI63672C (fi) 1983-08-10
PT72989B (en) 1983-07-06
AT380791B (de) 1986-07-10
SE437766B (sv) 1985-03-18
BE888822A (fr) 1981-11-16
GB2076422B (en) 1983-12-14
FR2482457B1 (es) 1985-01-04
DE3119745A1 (de) 1982-02-11
NO155429B (no) 1986-12-22
SE8103143L (sv) 1981-11-20
FI801610A (fi) 1981-11-20
PT72989A (en) 1981-06-01

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