SE9200858L - Metod för framställning av pellets med fördröjd frisättning - Google Patents

Metod för framställning av pellets med fördröjd frisättning

Info

Publication number
SE9200858L
SE9200858L SE9200858A SE9200858A SE9200858L SE 9200858 L SE9200858 L SE 9200858L SE 9200858 A SE9200858 A SE 9200858A SE 9200858 A SE9200858 A SE 9200858A SE 9200858 L SE9200858 L SE 9200858L
Authority
SE
Sweden
Prior art keywords
pct
binder
release pellets
sec
delayed release
Prior art date
Application number
SE9200858A
Other languages
Unknown language ( )
English (en)
Swedish (sv)
Other versions
SE9200858D0 (sv
Inventor
H G Kristensen
T Schaefer
L J Thomsen
A Kristensen
Original Assignee
Kabi Pharmacia Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kabi Pharmacia Ab filed Critical Kabi Pharmacia Ab
Priority to SE9200858A priority Critical patent/SE9200858L/
Publication of SE9200858D0 publication Critical patent/SE9200858D0/xx
Priority to AT93908213T priority patent/ATE154756T1/de
Priority to DE69311800T priority patent/DE69311800T2/de
Priority to PCT/SE1993/000225 priority patent/WO1993018753A1/fr
Priority to EP93908213A priority patent/EP0630235B1/fr
Priority to AU39111/93A priority patent/AU675062B2/en
Priority to CA002132451A priority patent/CA2132451C/fr
Priority to JP5516457A priority patent/JPH07505360A/ja
Priority to ES93908213T priority patent/ES2105240T3/es
Priority to DK93908213.7T priority patent/DK0630235T3/da
Priority to US08/307,629 priority patent/US5807583A/en
Publication of SE9200858L publication Critical patent/SE9200858L/
Priority to GR970402248T priority patent/GR3024604T3/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1611—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Processing And Handling Of Plastics And Other Materials For Molding In General (AREA)
  • Glanulating (AREA)
  • Disintegrating Or Milling (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
SE9200858A 1992-03-20 1992-03-20 Metod för framställning av pellets med fördröjd frisättning SE9200858L (sv)

Priority Applications (12)

Application Number Priority Date Filing Date Title
SE9200858A SE9200858L (sv) 1992-03-20 1992-03-20 Metod för framställning av pellets med fördröjd frisättning
US08/307,629 US5807583A (en) 1992-03-20 1993-03-16 Process for the preparation of sustained release pellets
EP93908213A EP0630235B1 (fr) 1992-03-20 1993-03-16 Procede de preparation de granules a liberation prolongee
DE69311800T DE69311800T2 (de) 1992-03-20 1993-03-16 Verfahren zur herstellung von pellets mit verzögerter freisetzung
PCT/SE1993/000225 WO1993018753A1 (fr) 1992-03-20 1993-03-16 Procede de preparation de granules a liberation prolongee
AT93908213T ATE154756T1 (de) 1992-03-20 1993-03-16 Verfahren zur herstellung von pellets mit verzögerter freisetzung
AU39111/93A AU675062B2 (en) 1992-03-20 1993-03-16 Process for the preparation of sustained release pellets
CA002132451A CA2132451C (fr) 1992-03-20 1993-03-16 Procede de preparation de comprimes a degagement prolonge
JP5516457A JPH07505360A (ja) 1992-03-20 1993-03-16 持効性ペレット剤の調製方法
ES93908213T ES2105240T3 (es) 1992-03-20 1993-03-16 Procedimiento para la preparacion de pellets de liberacion retardada.
DK93908213.7T DK0630235T3 (da) 1992-03-20 1993-03-16 Fremgangsmåde til fremstilling af pellets med forsinket frigivelse
GR970402248T GR3024604T3 (en) 1992-03-20 1997-09-02 Process for the preparation of sustained release pellets.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9200858A SE9200858L (sv) 1992-03-20 1992-03-20 Metod för framställning av pellets med fördröjd frisättning

Publications (2)

Publication Number Publication Date
SE9200858D0 SE9200858D0 (sv) 1992-03-20
SE9200858L true SE9200858L (sv) 1993-09-21

Family

ID=20385679

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9200858A SE9200858L (sv) 1992-03-20 1992-03-20 Metod för framställning av pellets med fördröjd frisättning

Country Status (12)

Country Link
US (1) US5807583A (fr)
EP (1) EP0630235B1 (fr)
JP (1) JPH07505360A (fr)
AT (1) ATE154756T1 (fr)
AU (1) AU675062B2 (fr)
CA (1) CA2132451C (fr)
DE (1) DE69311800T2 (fr)
DK (1) DK0630235T3 (fr)
ES (1) ES2105240T3 (fr)
GR (1) GR3024604T3 (fr)
SE (1) SE9200858L (fr)
WO (1) WO1993018753A1 (fr)

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US5478577A (en) * 1993-11-23 1995-12-26 Euroceltique, S.A. Method of treating pain by administering 24 hour oral opioid formulations exhibiting rapid rate of initial rise of plasma drug level
US5968551A (en) 1991-12-24 1999-10-19 Purdue Pharma L.P. Orally administrable opioid formulations having extended duration of effect
GB2284760B (en) * 1993-11-23 1998-06-24 Euro Celtique Sa A method of preparing pharmaceutical compositions by melt pelletisation
US5958459A (en) * 1991-12-24 1999-09-28 Purdue Pharma L.P. Opioid formulations having extended controlled released
IL109460A (en) * 1993-05-10 1998-03-10 Euro Celtique Sa Controlled release formulation comprising tramadol
GB9310030D0 (en) * 1993-05-15 1993-06-30 Scras Dry processed particles and process for the preparation of the same
US5690959A (en) * 1993-05-29 1997-11-25 Smithkline Beecham Corporation Pharmaceutical thermal infusion process
IL109944A (en) * 1993-07-01 1998-12-06 Euro Celtique Sa Continuous release dosage form containing morphine and a method of preparing such sustained release unit dosage forms
ES2168290T3 (es) * 1993-11-23 2002-06-16 Euro Celtique Sa Metodo para preparar una composicion de liberacion sostenida.
KR100354702B1 (ko) * 1993-11-23 2002-12-28 유로-셀티크 소시에떼 아노뉨 약학조성물의제조방법및서방형조성물
US6524832B1 (en) * 1994-02-04 2003-02-25 Arch Development Corporation DNA damaging agents in combination with tyrosine kinase inhibitors
EP0672416A1 (fr) * 1994-03-14 1995-09-20 Euro-Celtique S.A. Composition pharmaceutique à base de diamorphine
GB9422154D0 (en) † 1994-11-03 1994-12-21 Euro Celtique Sa Pharmaceutical compositions and method of producing the same
US5827537A (en) * 1995-05-04 1998-10-27 Smithkline Beecham Corporation Pharmaceutical thermal infusion process
GB9519363D0 (en) * 1995-09-22 1995-11-22 Euro Celtique Sa Pharmaceutical formulation
DE19705538C1 (de) * 1997-02-14 1998-08-27 Goedecke Ag Verfahren zur Trennung von Wirkstoffen in festen pharmazeutischen Zubereitungen
DE19729487A1 (de) * 1997-07-10 1999-01-14 Dresden Arzneimittel Verfahren zur Herstellung von Wirkstoff-Zubereitungen mit kontrollierter Freisetzung aus einer Matrix
ATE286721T1 (de) * 1997-09-19 2005-01-15 Shire Lab Inc Feste lösungskügelchen
DK173431B1 (da) 1998-03-20 2000-10-23 Gea Farmaceutisk Fabrik As Farmaceutisk formulering omfattende en 2-[[(2-pyridinyl)methyl]sulfinyl]benzimidazol med anti-ulcusaktivitet samt fremgangs
CA2389235C (fr) 1999-10-29 2007-07-17 Euro-Celtique, S.A. Formulations d'hydrocodone a liberation lente
US10179130B2 (en) 1999-10-29 2019-01-15 Purdue Pharma L.P. Controlled release hydrocodone formulations
US6953593B2 (en) * 2000-02-01 2005-10-11 Lipoprotein Technologies, Inc. Sustained-release microencapsulated delivery system
KR100713234B1 (ko) * 2000-10-02 2007-05-02 유에스브이 리미티드 메트포민을 함유하는 지속방출형 약학 조성물 및 이의제조방법
EP1195160B1 (fr) 2000-10-05 2009-09-16 USV Ltd. Composition pharmaceutique à effet de retard contenant de la trimétazidine et procédé pour sa préparation
EP2283829A1 (fr) 2000-10-30 2011-02-16 Euro-Celtique S.A. Formulations d'hydrocodone à liberation lente
IT1319655B1 (it) 2000-11-15 2003-10-23 Eurand Int Microsfere di enzimi pancreatici con elevata stabilita' e relativometodo di preparazione.
US20110104214A1 (en) 2004-04-15 2011-05-05 Purdue Pharma L.P. Once-a-day oxycodone formulations
US9107804B2 (en) * 2002-12-10 2015-08-18 Nortec Development Associates, Inc. Method of preparing biologically active formulations
DE10300325A1 (de) 2003-01-09 2004-07-22 Hexal Ag Granulat mit öliger Substanz, Herstellungsverfahren und Tablette
KR100712356B1 (ko) * 2003-01-23 2007-05-02 (주)아모레퍼시픽 서방성 제제 및 그의 제조방법
US8034605B2 (en) * 2003-03-26 2011-10-11 Kyu-Jin Yum Microbial materials for degradation of oils and toxic chemicals
KR100412759B1 (en) * 2003-03-26 2004-01-07 Kyu Jin Yum Microbial preparation for decomposing oils and toxic chemicals
US20090214644A1 (en) * 2003-07-31 2009-08-27 Xanodyne Pharmaceuticals, Inc. Tranexamic acid formulations with reduced adverse effects
US20050025825A1 (en) * 2003-07-31 2005-02-03 Xanodyne Pharmacal, Inc. Tranexamic acid formulations with reduced adverse effects
AU2004267100B2 (en) * 2003-08-20 2010-10-07 Xenoport, Inc. Acyloxyalkyl carbamate prodrugs, methods of synthesis and use
ES2405329T3 (es) 2003-12-30 2013-05-30 Xenoport, Inc. Síntesis de profármacos de carbarnato de aciloxialquilo y productos intermedios de los mismos
US20050244495A1 (en) * 2004-03-04 2005-11-03 Xanodyne Pharmaceuticals, Inc. Tranexamic acid formulations
US20050245614A1 (en) * 2004-03-04 2005-11-03 Xanodyne Pharmaceuticals, Inc. Tranexamic acid formulations
US20090215898A1 (en) * 2004-03-04 2009-08-27 Xanodyne Pharmaceuticals, Inc. Tranexamic acid formulations
US7947739B2 (en) 2004-03-04 2011-05-24 Ferring B.V. Tranexamic acid formulations
US8022106B2 (en) * 2004-03-04 2011-09-20 Ferring B.V. Tranexamic acid formulations
EP1753405A4 (fr) * 2004-06-10 2008-09-17 Glatt Air Tech Inc Preparation pharmaceutique a liberation lente
PL2001445T3 (pl) * 2006-03-16 2015-06-30 Euro Celtique Sa Farmaceutyczne sferoidy
SG186648A1 (en) 2007-02-20 2013-01-30 Aptalis Pharma Ltd Stable digestive enzyme compositions
CA2678367C (fr) * 2007-03-02 2014-07-08 Farnam Companies, Inc. Compositions a liberation prolongee utilisant des matieres cireuses
US10087493B2 (en) 2008-03-07 2018-10-02 Aptalis Pharma Canada Ulc Method for detecting infectious parvovirus in pharmaceutical preparations
US20100280117A1 (en) * 2009-04-30 2010-11-04 Xanodyne Pharmaceuticals, Inc. Menorrhagia Instrument and Method for the Treatment of Menstrual Bleeding Disorders
UA111726C2 (uk) 2010-10-01 2016-06-10 Апталіс Фарма Лімітед Препарат панкреліпази низької сили з кишковорозчинним покриттям
AU2012293325B2 (en) 2011-08-08 2015-05-07 Allergan Pharmaceuticals International Limited Method for dissolution testing of solid compositions containing digestive enzymes
CA2859174C (fr) * 2011-12-12 2019-03-05 Orbis Biosciences, Inc. Formulations de particules a liberation prolongee
US10993996B2 (en) 2013-08-09 2021-05-04 Allergan Pharmaceuticals International Limited Digestive enzyme composition suitable for enteral administration
US11813361B2 (en) 2014-04-04 2023-11-14 Pharmaquest International Center, Llp Disintegrating monolithic modified release tablets containing quadri-layer extended release granules
WO2015193730A1 (fr) 2014-06-19 2015-12-23 Aptalis Pharma Ltd. Procédés d'élimination de contaminants viraux dans des extraits pancréatiques
US20170042806A1 (en) 2015-04-29 2017-02-16 Dexcel Pharma Technologies Ltd. Orally disintegrating compositions
US10076494B2 (en) 2016-06-16 2018-09-18 Dexcel Pharma Technologies Ltd. Stable orally disintegrating pharmaceutical compositions

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US4132753A (en) * 1965-02-12 1979-01-02 American Cyanamid Company Process for preparing oral sustained release granules
DE2360796B2 (de) * 1973-12-06 1977-06-02 Edelfettwerke Werner Schlüter, 2000 Hamburg; Glyco Iberica S.A., Gava, Barcelona (Spanien) Vti: Hegel, K.Th., Dr.; Dickel, K., Dipl.-Ing.; Pat.-Anwälte, 2000 Hamburg und 8000 München Arzneimittel mit verzoegerter abgabe des wirkstoffs im darm
US5008112A (en) * 1985-12-16 1991-04-16 International Minerals & Chem. Corporation Device for the extended delivery of diffusible agents
DE3721721C1 (de) * 1987-07-01 1988-06-09 Hoechst Ag Verfahren zur Umhuellung von Granulaten
JP2681373B2 (ja) * 1988-07-18 1997-11-26 塩野義製薬株式会社 徐放性製剤の製造法
DK161743C (da) * 1989-07-03 1992-02-17 Niro Atomizer As Fremgangsmaade og apparat til agglomerering af et pulverformigt materiale
SE9003296L (sv) * 1990-10-16 1992-04-17 Kabi Pharmacia Ab Foerfarande foer att formulera laekemedel
US5358560A (en) * 1991-10-04 1994-10-25 Eastman Chemical Company Solid-form additive systems dispersible in aqueous media and method for their preparation

Also Published As

Publication number Publication date
SE9200858D0 (sv) 1992-03-20
DE69311800T2 (de) 1998-01-08
US5807583A (en) 1998-09-15
DE69311800D1 (de) 1997-07-31
CA2132451A1 (fr) 1993-09-30
ATE154756T1 (de) 1997-07-15
ES2105240T3 (es) 1997-10-16
JPH07505360A (ja) 1995-06-15
AU3911193A (en) 1993-10-21
EP0630235A1 (fr) 1994-12-28
DK0630235T3 (da) 1998-02-02
AU675062B2 (en) 1997-01-23
EP0630235B1 (fr) 1997-06-25
CA2132451C (fr) 2003-06-10
GR3024604T3 (en) 1997-12-31
WO1993018753A1 (fr) 1993-09-30

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