GR3024604T3 - Process for the preparation of sustained release pellets. - Google Patents

Process for the preparation of sustained release pellets.

Info

Publication number
GR3024604T3
GR3024604T3 GR970402248T GR970402248T GR3024604T3 GR 3024604 T3 GR3024604 T3 GR 3024604T3 GR 970402248 T GR970402248 T GR 970402248T GR 970402248 T GR970402248 T GR 970402248T GR 3024604 T3 GR3024604 T3 GR 3024604T3
Authority
GR
Greece
Prior art keywords
pct
binder
sustained release
release pellets
sec
Prior art date
Application number
GR970402248T
Other languages
English (en)
Inventor
Henning G Kristensen
Torben Schaefer
Lars Juul Thomsen
Arne Kristensen
Original Assignee
Pharmacia Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Ab filed Critical Pharmacia Ab
Publication of GR3024604T3 publication Critical patent/GR3024604T3/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1611—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
GR970402248T 1992-03-20 1997-09-02 Process for the preparation of sustained release pellets. GR3024604T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9200858A SE9200858L (sv) 1992-03-20 1992-03-20 Metod för framställning av pellets med fördröjd frisättning
PCT/SE1993/000225 WO1993018753A1 (en) 1992-03-20 1993-03-16 Process for the preparation of sustained release pellets

Publications (1)

Publication Number Publication Date
GR3024604T3 true GR3024604T3 (en) 1997-12-31

Family

ID=20385679

Family Applications (1)

Application Number Title Priority Date Filing Date
GR970402248T GR3024604T3 (en) 1992-03-20 1997-09-02 Process for the preparation of sustained release pellets.

Country Status (12)

Country Link
US (1) US5807583A (el)
EP (1) EP0630235B1 (el)
JP (1) JPH07505360A (el)
AT (1) ATE154756T1 (el)
AU (1) AU675062B2 (el)
CA (1) CA2132451C (el)
DE (1) DE69311800T2 (el)
DK (1) DK0630235T3 (el)
ES (1) ES2105240T3 (el)
GR (1) GR3024604T3 (el)
SE (1) SE9200858L (el)
WO (1) WO1993018753A1 (el)

Families Citing this family (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5958459A (en) * 1991-12-24 1999-09-28 Purdue Pharma L.P. Opioid formulations having extended controlled released
US5968551A (en) 1991-12-24 1999-10-19 Purdue Pharma L.P. Orally administrable opioid formulations having extended duration of effect
US5478577A (en) * 1993-11-23 1995-12-26 Euroceltique, S.A. Method of treating pain by administering 24 hour oral opioid formulations exhibiting rapid rate of initial rise of plasma drug level
GB2284760B (en) * 1993-11-23 1998-06-24 Euro Celtique Sa A method of preparing pharmaceutical compositions by melt pelletisation
IL119660A (en) * 1993-05-10 2002-09-12 Euro Celtique Sa Controlled release formulation comprising tramadol
GB9310030D0 (en) * 1993-05-15 1993-06-30 Scras Dry processed particles and process for the preparation of the same
US5690959A (en) * 1993-05-29 1997-11-25 Smithkline Beecham Corporation Pharmaceutical thermal infusion process
IL109944A (en) * 1993-07-01 1998-12-06 Euro Celtique Sa Continuous release dosage form containing morphine and a method of preparing such sustained release unit dosage forms
ATE212224T1 (de) * 1993-11-23 2002-02-15 Euro Celtique Sa Verfahren zur herstellung einer arzneizusammensetzung mit verzögerter wirkstoffabgabe
KR100354702B1 (ko) * 1993-11-23 2002-12-28 유로-셀티크 소시에떼 아노뉨 약학조성물의제조방법및서방형조성물
US6524832B1 (en) * 1994-02-04 2003-02-25 Arch Development Corporation DNA damaging agents in combination with tyrosine kinase inhibitors
EP0672416A1 (en) * 1994-03-14 1995-09-20 Euro-Celtique S.A. Pharmaceutical composition comprising diamorphine
GB9422154D0 (en) † 1994-11-03 1994-12-21 Euro Celtique Sa Pharmaceutical compositions and method of producing the same
US5827537A (en) * 1995-05-04 1998-10-27 Smithkline Beecham Corporation Pharmaceutical thermal infusion process
GB9519363D0 (en) * 1995-09-22 1995-11-22 Euro Celtique Sa Pharmaceutical formulation
DE19705538C1 (de) * 1997-02-14 1998-08-27 Goedecke Ag Verfahren zur Trennung von Wirkstoffen in festen pharmazeutischen Zubereitungen
DE19729487A1 (de) * 1997-07-10 1999-01-14 Dresden Arzneimittel Verfahren zur Herstellung von Wirkstoff-Zubereitungen mit kontrollierter Freisetzung aus einer Matrix
AU9496798A (en) * 1997-09-19 1999-04-05 Shire Laboratories, Inc. Solid solution beadlet
DK173431B1 (da) 1998-03-20 2000-10-23 Gea Farmaceutisk Fabrik As Farmaceutisk formulering omfattende en 2-[[(2-pyridinyl)methyl]sulfinyl]benzimidazol med anti-ulcusaktivitet samt fremgangs
US10179130B2 (en) 1999-10-29 2019-01-15 Purdue Pharma L.P. Controlled release hydrocodone formulations
NZ529928A (en) 1999-10-29 2005-10-28 Euro Celtique Sa Controlled release hydrocodone formulations
US6953593B2 (en) * 2000-02-01 2005-10-11 Lipoprotein Technologies, Inc. Sustained-release microencapsulated delivery system
JP2004510716A (ja) * 2000-10-02 2004-04-08 ユーエスヴイ　リミテッド メトフォルミン含有持続性放出薬理組成物とその製造方法
ATE442852T1 (de) 2000-10-05 2009-10-15 Usv Ltd Trimetazidine enthaltendes arzneimittel mit verzögerter wirkstoffabgabe und verfahren zur herstellung
KR101045144B1 (ko) 2000-10-30 2011-06-30 유로-셀티크 소시에떼 아노뉨 서방성 하이드로코돈 제형
IT1319655B1 (it) 2000-11-15 2003-10-23 Eurand Int Microsfere di enzimi pancreatici con elevata stabilita' e relativometodo di preparazione.
US20110104214A1 (en) 2004-04-15 2011-05-05 Purdue Pharma L.P. Once-a-day oxycodone formulations
US9107804B2 (en) 2002-12-10 2015-08-18 Nortec Development Associates, Inc. Method of preparing biologically active formulations
DE10300325A1 (de) 2003-01-09 2004-07-22 Hexal Ag Granulat mit öliger Substanz, Herstellungsverfahren und Tablette
CN100500130C (zh) * 2003-01-23 2009-06-17 株式会社太平洋 缓释制剂及其制备方法
US8034605B2 (en) * 2003-03-26 2011-10-11 Kyu-Jin Yum Microbial materials for degradation of oils and toxic chemicals
KR100412759B1 (en) * 2003-03-26 2004-01-07 Kyu Jin Yum Microbial preparation for decomposing oils and toxic chemicals
US20050025825A1 (en) * 2003-07-31 2005-02-03 Xanodyne Pharmacal, Inc. Tranexamic acid formulations with reduced adverse effects
US20090214644A1 (en) * 2003-07-31 2009-08-27 Xanodyne Pharmaceuticals, Inc. Tranexamic acid formulations with reduced adverse effects
PT1660440E (pt) 2003-08-20 2012-05-15 Xenoport Inc Pró-fármacos de aciloxialquilcarbamato, métodos de síntese e utilização
JP4927563B2 (ja) * 2003-12-30 2012-05-09 ゼノポート，インコーポレイティド アシルオキシアルキルカルバメートプロドラッグ及び中間体の合成
US7947739B2 (en) 2004-03-04 2011-05-24 Ferring B.V. Tranexamic acid formulations
US20050245614A1 (en) * 2004-03-04 2005-11-03 Xanodyne Pharmaceuticals, Inc. Tranexamic acid formulations
US8022106B2 (en) * 2004-03-04 2011-09-20 Ferring B.V. Tranexamic acid formulations
US20050244495A1 (en) 2004-03-04 2005-11-03 Xanodyne Pharmaceuticals, Inc. Tranexamic acid formulations
US20090215898A1 (en) * 2004-03-04 2009-08-27 Xanodyne Pharmaceuticals, Inc. Tranexamic acid formulations
WO2005123042A1 (en) * 2004-06-10 2005-12-29 Glatt Air Techniques, Inc. Controlled release pharmaceutical formulation
ES2516693T3 (es) * 2006-03-16 2014-10-31 Euro-Celtique S.A. Esferoides farmacéuticos
PL2079445T3 (pl) 2007-02-20 2016-04-29 Allergan Pharmaceuticals Int Ltd Stabilne kompozycje enzymów trawiennych
ATE476176T1 (de) * 2007-03-02 2010-08-15 Farnam Co Inc Wachsähnliches material enthaltende tabletten mit verzögerter freisetzung
US10087493B2 (en) 2008-03-07 2018-10-02 Aptalis Pharma Canada Ulc Method for detecting infectious parvovirus in pharmaceutical preparations
US20100280117A1 (en) * 2009-04-30 2010-11-04 Xanodyne Pharmaceuticals, Inc. Menorrhagia Instrument and Method for the Treatment of Menstrual Bleeding Disorders
KR101968457B1 (ko) 2010-10-01 2019-04-11 앨러간 파마슈티컬스 인터내셔널 리미티드 장용 코팅된 저 강도 췌장 리파제 제제
RU2016119726A (ru) 2011-08-08 2018-11-02 Апталис Фарма Лтд. Способ проведения теста на растворение твердых композиций, содержащих пищеварительные ферменты
EP4035683A1 (en) * 2011-12-12 2022-08-03 Adare Pharmaceuticals USA, Inc. Sustained release particle formulations
US10184121B2 (en) 2013-06-28 2019-01-22 Allergan Pharmaceuticals International Limited Methods for removing viral contaminants from pancreatic extracts
ES2784227T3 (es) 2013-08-09 2020-09-23 Allergan Pharmaceuticals Int Ltd Composición de enzimas digestivos adecuada para la administración entérica
WO2015153984A2 (en) 2014-04-04 2015-10-08 Pharmaquest International Center, LLC Disintegrating monolithic modified release tablets containing quadri-layer extended release granules
US20170042806A1 (en) 2015-04-29 2017-02-16 Dexcel Pharma Technologies Ltd. Orally disintegrating compositions
US10076494B2 (en) 2016-06-16 2018-09-18 Dexcel Pharma Technologies Ltd. Stable orally disintegrating pharmaceutical compositions

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4132753A (en) * 1965-02-12 1979-01-02 American Cyanamid Company Process for preparing oral sustained release granules
DE2360796B2 (de) * 1973-12-06 1977-06-02 Edelfettwerke Werner Schlüter, 2000 Hamburg; Glyco Iberica S.A., Gava, Barcelona (Spanien) Vti: Hegel, K.Th., Dr.; Dickel, K., Dipl.-Ing.; Pat.-Anwälte, 2000 Hamburg und 8000 München Arzneimittel mit verzoegerter abgabe des wirkstoffs im darm
US5008112A (en) * 1985-12-16 1991-04-16 International Minerals & Chem. Corporation Device for the extended delivery of diffusible agents
DE3721721C1 (de) * 1987-07-01 1988-06-09 Hoechst Ag Verfahren zur Umhuellung von Granulaten
JP2681373B2 (ja) * 1988-07-18 1997-11-26 塩野義製薬株式会社 徐放性製剤の製造法
DK161743C (da) * 1989-07-03 1992-02-17 Niro Atomizer As Fremgangsmaade og apparat til agglomerering af et pulverformigt materiale
SE9003296L (sv) * 1990-10-16 1992-04-17 Kabi Pharmacia Ab Foerfarande foer att formulera laekemedel
US5358560A (en) * 1991-10-04 1994-10-25 Eastman Chemical Company Solid-form additive systems dispersible in aqueous media and method for their preparation

Also Published As

Publication number Publication date
AU3911193A (en) 1993-10-21
ES2105240T3 (es) 1997-10-16
SE9200858L (sv) 1993-09-21
CA2132451A1 (en) 1993-09-30
WO1993018753A1 (en) 1993-09-30
ATE154756T1 (de) 1997-07-15
US5807583A (en) 1998-09-15
JPH07505360A (ja) 1995-06-15
DK0630235T3 (da) 1998-02-02
DE69311800T2 (de) 1998-01-08
CA2132451C (en) 2003-06-10
EP0630235B1 (en) 1997-06-25
EP0630235A1 (en) 1994-12-28
SE9200858D0 (sv) 1992-03-20
DE69311800D1 (de) 1997-07-31
AU675062B2 (en) 1997-01-23

Similar Documents

Publication Publication Date Title
GR3024604T3 (en) Process for the preparation of sustained release pellets.
DE69115711T2 (de) Verfahren zur arzneiformulierung sowie arzneimittel
GB2186485B (en) Slow release formulation
ATE35422T1 (de) Verfahren zur herstellung von pigmentzusammensetzungen.
ATE92711T1 (de) Latex enthaltende agrochemische zusammensetzungen.
BR9810168A (pt) Processo para produção de um produto detergente granular, e, produto detergente granular
WO1999031141A3 (de) Verfahren zur herstellung von regulären porösen perlcellulosen, die perlcellulosen und ihre verwendung
GEP19981475B (en) Solid Group Preparation for Shielding of ultivated Plants and Method for Its Production
GB1275173A (en) Bleaching compositions
AU5153696A (en) New additive concentrates
DE69525620D1 (de) Verfahren für die herstellung schmelz-granulierte sucralfatzubereitung
PL287646A1 (en) Binding agent and binding mixture for use to agglomerate powdered material, agglomerated materials obtained thereby and method of obtaining such agglomerated materials
RU92014183A (ru) Способ приготовления боросодержащей композиции
JPS57163308A (en) Depilating wax
SU141492A1 (ru) Способ внедоменного обессеривани чугуна
JPS53130282A (en) Granulating method for powder
ATE56752T1 (de) Verfahren zur herstellung einer poroesen struktur, die eine in einem bindemittel ausgestreute organische substanz enthaelt.
de Menezes et al. Valence Fluctuation in Eu--Transition Metal Compounds
STEFANESCU et al. Particle Engulfment and Pushing by Solidifying Interfaces(PEPSI)(Final Report)
JPS5672660A (en) Granulated and refined konjak flour and its preparation
RU92009160A (ru) Способ получения белкового корма
TH26411A (th) กรรมวิธีในการเตรียมผลิตภัณฑ์สารซักฟอก