DK0614455T3 - Vitamin D-amidderivater - Google Patents

Vitamin D-amidderivater

Info

Publication number
DK0614455T3
DK0614455T3 DK92922932.6T DK92922932T DK0614455T3 DK 0614455 T3 DK0614455 T3 DK 0614455T3 DK 92922932 T DK92922932 T DK 92922932T DK 0614455 T3 DK0614455 T3 DK 0614455T3
Authority
DK
Denmark
Prior art keywords
vitamin
amide derivatives
alpha
azacholesta
seco
Prior art date
Application number
DK92922932.6T
Other languages
Danish (da)
English (en)
Inventor
Robert Henry Hesse
Gaddam Subba Reddy
Sundara Katugam S Setty
Original Assignee
Res Inst Medicine Chem
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB919123712A external-priority patent/GB9123712D0/en
Priority claimed from GB929209658A external-priority patent/GB9209658D0/en
Application filed by Res Inst Medicine Chem filed Critical Res Inst Medicine Chem
Application granted granted Critical
Publication of DK0614455T3 publication Critical patent/DK0614455T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
DK92922932.6T 1991-11-07 1992-11-06 Vitamin D-amidderivater DK0614455T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB919123712A GB9123712D0 (en) 1991-11-07 1991-11-07 Chemical compounds
GB929209658A GB9209658D0 (en) 1992-05-05 1992-05-05 Chemical compounds

Publications (1)

Publication Number Publication Date
DK0614455T3 true DK0614455T3 (da) 1996-03-18

Family

ID=26299825

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92922932.6T DK0614455T3 (da) 1991-11-07 1992-11-06 Vitamin D-amidderivater

Country Status (20)

Country Link
US (2) US5494905A (enExample)
EP (1) EP0614455B1 (enExample)
JP (1) JP3282811B2 (enExample)
KR (1) KR100271461B1 (enExample)
AT (1) ATE134366T1 (enExample)
AU (1) AU664213B2 (enExample)
CA (1) CA2121678C (enExample)
CZ (1) CZ288031B6 (enExample)
DE (1) DE69208478T2 (enExample)
DK (1) DK0614455T3 (enExample)
ES (1) ES2083771T3 (enExample)
FI (1) FI106119B (enExample)
GR (1) GR3019601T3 (enExample)
HU (1) HU221008B1 (enExample)
NO (1) NO305315B1 (enExample)
NZ (1) NZ245041A (enExample)
PL (1) PL171580B1 (enExample)
RU (1) RU2139276C1 (enExample)
SK (1) SK281302B6 (enExample)
WO (1) WO1993009093A1 (enExample)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL171580B1 (pl) * 1991-11-07 1997-05-30 Res Inst Medicine Chem Sposób wytwarzania nowych analogów witaminy D3 PL PL PL
IL107185A (en) * 1992-10-06 1998-02-22 Schering Ag Vitamin d, 25-carboxylic acid derivatives and pharmaceutical compositions containing the same
US5662604A (en) * 1993-02-12 1997-09-02 Asahi Kasei Kogyo Kabushiki Kaisha Monitoring method of renal lesions without clinical signs
GB9309422D0 (en) * 1993-05-07 1993-06-23 Res Inst Medicine Chem Chemical compounds
GB9325415D0 (en) * 1993-12-13 1994-02-16 Res Inst Medicine Chem Chemical compounds
GB9405715D0 (en) * 1994-03-23 1994-05-11 Res Inst Medicine Chem Chemical compounds
US5661141A (en) * 1995-03-27 1997-08-26 Petrow; Vladimir 19-oxygenated steroids as therapeutic agents
US5678570A (en) * 1995-04-14 1997-10-21 The University Of North Carolina At Chapel Hill Method of treating cardiac arrest
US5696103A (en) * 1995-11-17 1997-12-09 Syntex (U.S.A.) Inc. Method for treating osteoporosis
DE19619036A1 (de) * 1996-04-30 1997-11-13 Schering Ag Neue Vitamin D-Derivate mit carbo- oder heterocyclischen Substituenten an C-25, Verfahren zu ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln
US6043385A (en) * 1997-12-16 2000-03-28 Hoffman-La Roche Inc. Vitamin D derivatives
GB9804861D0 (en) 1998-03-06 1998-04-29 Res Inst Medicine Chem Chemical compounds
EP1123921A4 (en) * 1998-10-23 2003-08-20 Teijin Ltd VITAMIN D 3 DERIVATIVES? AND MEDICINES FOR INFLAMMATORY RESPIRATORY DISEASES CONTAINING THEM
DE19935771A1 (de) * 1999-07-23 2001-02-01 Schering Ag Neue Vitamin D-Derivate mit cyclischen Substrukturen in den Seitenketten, Verfahren und Zwischenprodukte zu ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln
US6703380B2 (en) 1999-09-29 2004-03-09 Colotech A/S Prevention of cancer
DK1220676T3 (da) 1999-09-29 2005-09-05 Colotech As Forebyggelse af colorektal cancer
WO2001030751A2 (en) * 1999-10-25 2001-05-03 Strakan Limited USES OF 1,25-DIHYDROXY-5,6-trans VITAMIN D COMPOUNDS AND DERIVATIVES THEREOF
CN100469764C (zh) * 2000-06-15 2009-03-18 中外制药株式会社 维生素d衍生物
CA2586679A1 (en) 2004-11-12 2006-05-18 Bioxell Spa Combined use of vitamin d derivatives and anti-proliferative agents for treating bladder cancer
EP2018366A4 (en) * 2006-05-16 2010-08-04 Univ Mcgill HYBRID MOLECULES WITH MIXED VITAMIN D RECEPTOR AGONISM AND HISTONDEACETYLASE RESISTANT PROPERTIES
WO2009117831A1 (en) * 2008-03-27 2009-10-01 The Royal Institution For The Advancement Of Learning/Mcgill University Hybrid molecules having mixed vitamin d receptor agonism and histone deacetylase inhibitory properties
US8987235B2 (en) 2011-05-17 2015-03-24 Wisconsin Alumni Research Foundation N-cyclopropyl-(20R)-2-methylene-19,26,27-trinor-25-aza-vitamin D analogs and their uses
IL300818A (en) * 2020-09-15 2023-04-01 Teijin Pharma Ltd A vitamin D derivative with a cyclic amine in the side chain

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4217288A (en) * 1977-03-24 1980-08-12 Wisconsin Alumni Research Foundation Anti-vitamin D compounds
FR2426044A2 (fr) * 1978-05-19 1979-12-14 Wisconsin Research Foundation Derives de la vitamine d3 ayant une activite anti-vitamine d
CA1317962C (en) * 1987-07-29 1993-05-18 Naoto Hashimoto Cell proliferation inhibitors
US5206230A (en) * 1991-06-05 1993-04-27 Daikin Industries, Ltd. Fluorine-containing vitamin D3 analogues and pharmaceutical composition containing the same
PL171580B1 (pl) * 1991-11-07 1997-05-30 Res Inst Medicine Chem Sposób wytwarzania nowych analogów witaminy D3 PL PL PL

Also Published As

Publication number Publication date
HUT67140A (en) 1995-02-28
PL171580B1 (pl) 1997-05-30
EP0614455B1 (en) 1996-02-21
CZ288031B6 (cs) 2001-04-11
FI942114L (fi) 1994-05-06
HU9401372D0 (en) 1994-08-29
CZ111294A3 (en) 1995-03-15
NZ245041A (en) 1995-03-28
US5494905A (en) 1996-02-27
KR100271461B1 (ko) 2000-11-15
NO941683D0 (no) 1994-05-06
WO1993009093A1 (en) 1993-05-13
RU2139276C1 (ru) 1999-10-10
US5686435A (en) 1997-11-11
DE69208478D1 (de) 1996-03-28
HU221008B1 (hu) 2002-07-29
CA2121678A1 (en) 1993-05-13
ES2083771T3 (es) 1996-04-16
AU664213B2 (en) 1995-11-09
SK281302B6 (sk) 2001-02-12
AU2901492A (en) 1993-06-07
FI106119B (fi) 2000-11-30
JPH07502499A (ja) 1995-03-16
JP3282811B2 (ja) 2002-05-20
NO305315B1 (no) 1999-05-10
EP0614455A1 (en) 1994-09-14
GR3019601T3 (en) 1996-07-31
DE69208478T2 (de) 1996-09-05
ATE134366T1 (de) 1996-03-15
CA2121678C (en) 2005-03-15
SK52294A3 (en) 1994-11-09
NO941683L (enExample) 1994-06-27
FI942114A0 (fi) 1994-05-06

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