ATE120188T1 - 15-deoxyprostaglandinderivat. - Google Patents
15-deoxyprostaglandinderivat.Info
- Publication number
- ATE120188T1 ATE120188T1 AT91905484T AT91905484T ATE120188T1 AT E120188 T1 ATE120188 T1 AT E120188T1 AT 91905484 T AT91905484 T AT 91905484T AT 91905484 T AT91905484 T AT 91905484T AT E120188 T1 ATE120188 T1 AT E120188T1
- Authority
- AT
- Austria
- Prior art keywords
- formula
- inderivate
- deoxyprostagland
- derivative
- alkyl
- Prior art date
Links
- 125000006539 C12 alkyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000000994 depressogenic effect Effects 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 230000004410 intraocular pressure Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Developing Agents For Electrophotography (AREA)
- Control Of Electric Motors In General (AREA)
- Dental Preparations (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP5747690 | 1990-03-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE120188T1 true ATE120188T1 (de) | 1995-04-15 |
Family
ID=13056760
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT91905484T ATE120188T1 (de) | 1990-03-08 | 1991-03-07 | 15-deoxyprostaglandinderivat. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5599837A (de) |
| EP (1) | EP0471856B1 (de) |
| JP (1) | JP3164368B2 (de) |
| KR (1) | KR100224951B1 (de) |
| AT (1) | ATE120188T1 (de) |
| AU (1) | AU640767B2 (de) |
| CA (1) | CA2054738C (de) |
| DE (1) | DE69108326T2 (de) |
| DK (1) | DK0471856T3 (de) |
| ES (1) | ES2069881T3 (de) |
| WO (1) | WO1991013869A1 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH06107547A (ja) * | 1992-10-01 | 1994-04-19 | Aarutetsuku Ueno:Kk | 眼科用組成物 |
| SE9401087D0 (sv) * | 1994-03-31 | 1994-03-31 | Pharmacia Ab | New prostaglandin derivatives for the treatment of glaucoma or ocular hypertension |
| US20020052413A1 (en) * | 2000-07-19 | 2002-05-02 | Christine Percicot | Treatment of ocular complications |
| CN114262288B (zh) * | 2020-09-16 | 2023-07-07 | 凯特立斯（深圳）科技有限公司 | 一类前列腺素类化合物合成关键中间体及其制备方法 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3290226A (en) * | 1964-02-19 | 1966-12-06 | Upjohn Co | Microbiological conversion of unsaturated fatty acids |
| US3847962A (en) * | 1972-05-12 | 1974-11-12 | Syntex Inc | Prostaglandins and process and intermediates therefor |
| US3872139A (en) * | 1972-05-12 | 1975-03-18 | Syntex Inc | 15 Deoxy PGE{HD 2 |
| CA1045131A (en) * | 1972-07-24 | 1978-12-26 | Middleton B. Floyd (Jr.) | Derivatives of 9-hydroxy-13-trans-prostenoic acid |
| GB1440361A (en) * | 1972-07-24 | 1976-06-23 | American Cyanamid Co | 11-deoxyprostaglandins of the e and f series and the preparation thereof |
| JPS5032151A (de) * | 1973-07-27 | 1975-03-28 | ||
| JPS5037753A (de) * | 1973-08-13 | 1975-04-08 | ||
| US4599353A (en) * | 1982-05-03 | 1986-07-08 | The Trustees Of Columbia University In The City Of New York | Use of eicosanoids and their derivatives for treatment of ocular hypertension and glaucoma |
| JPS58216155A (ja) * | 1982-06-10 | 1983-12-15 | Ono Pharmaceut Co Ltd | 新規なプロスタグランジンｄ類似化合物 |
| HU196174B (en) * | 1984-07-31 | 1988-10-28 | Syntex Inc | Process for preparing new prostaglandin derivatives and pharmaceutical compositions containing such active substance |
| ES2053458T3 (es) * | 1986-03-13 | 1994-08-01 | Univ Columbia | Utilizacion de prostaglandinas a, b y c y derivados de las mismas, para el tratamiento de la hipertension ocular y glaucoma. |
| DE3876050T2 (de) * | 1987-09-18 | 1993-03-25 | Ueno Seiyaku Oyo Kenkyujo Kk | Okulare hypotensivagenzien. |
| JPH022108A (ja) * | 1988-06-15 | 1990-01-08 | Nec Corp | シンクロトロン放射光露光装置 |
| EP0444844B1 (de) * | 1990-02-26 | 1995-01-18 | R-Tech Ueno Ltd. | 15-Dehydroxy-16-oxoprostaglandine |
| US5157052A (en) * | 1990-12-27 | 1992-10-20 | Monsanto Company | Method for inhibiting ige production |
-
1991
- 1991-03-07 CA CA002054738A patent/CA2054738C/en not_active Expired - Fee Related
- 1991-03-07 EP EP91905484A patent/EP0471856B1/de not_active Expired - Lifetime
- 1991-03-07 DE DE69108326T patent/DE69108326T2/de not_active Expired - Fee Related
- 1991-03-07 DK DK91905484.1T patent/DK0471856T3/da active
- 1991-03-07 KR KR1019910701543A patent/KR100224951B1/ko not_active IP Right Cessation
- 1991-03-07 AT AT91905484T patent/ATE120188T1/de not_active IP Right Cessation
- 1991-03-07 ES ES91905484T patent/ES2069881T3/es not_active Expired - Lifetime
- 1991-03-07 WO PCT/JP1991/000305 patent/WO1991013869A1/ja active IP Right Grant
- 1991-03-07 JP JP50531991A patent/JP3164368B2/ja not_active Expired - Fee Related
- 1991-03-07 AU AU74514/91A patent/AU640767B2/en not_active Ceased
-
1995
- 1995-02-28 US US08/395,642 patent/US5599837A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2054738A1 (en) | 1991-09-09 |
| KR920701149A (ko) | 1992-08-11 |
| DK0471856T3 (da) | 1995-06-06 |
| EP0471856A1 (de) | 1992-02-26 |
| EP0471856A4 (en) | 1992-08-05 |
| JP3164368B2 (ja) | 2001-05-08 |
| AU7451491A (en) | 1991-10-10 |
| DE69108326D1 (en) | 1995-04-27 |
| CA2054738C (en) | 2001-08-28 |
| EP0471856B1 (de) | 1995-03-22 |
| US5599837A (en) | 1997-02-04 |
| DE69108326T2 (de) | 1995-07-27 |
| ES2069881T3 (es) | 1995-05-16 |
| WO1991013869A1 (en) | 1991-09-19 |
| AU640767B2 (en) | 1993-09-02 |
| KR100224951B1 (ko) | 1999-10-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| REN | Ceased due to non-payment of the annual fee |