ES2053458T3 - Utilizacion de prostaglandinas a, b y c y derivados de las mismas, para el tratamiento de la hipertension ocular y glaucoma. - Google Patents

Utilizacion de prostaglandinas a, b y c y derivados de las mismas, para el tratamiento de la hipertension ocular y glaucoma.

Info

Publication number
ES2053458T3
ES2053458T3 ES87103714T ES87103714T ES2053458T3 ES 2053458 T3 ES2053458 T3 ES 2053458T3 ES 87103714 T ES87103714 T ES 87103714T ES 87103714 T ES87103714 T ES 87103714T ES 2053458 T3 ES2053458 T3 ES 2053458T3
Authority
ES
Spain
Prior art keywords
pga
eye
glaucoma
derivatives
pgb
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES87103714T
Other languages
English (en)
Inventor
Laszlo Z Bito
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Columbia University in the City of New York
Original Assignee
Columbia University in the City of New York
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/022,046 external-priority patent/US4883819A/en
Application filed by Columbia University in the City of New York filed Critical Columbia University in the City of New York
Application granted granted Critical
Publication of ES2053458T3 publication Critical patent/ES2053458T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Ophthalmology & Optometry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

ESTA INVENCION PROPORCIONA UN METODO PARA TRATAR LA HIPERTENSION O EL GLAUCOMA EN UN OJO, QUE COMPRENDE CONTACTAR LA SUPERFICIE DEL OJO CON UNA CANTIDAD EFICAZ PARA REDUCIR LA PRESION INTRAOCULAR, DE UNA O MAS PROSTAGLANDINAS ELEGIDAS DEL GRUPO QUE CONSTA DE PROSTAGLANDINA A (PGA), PROSTAGLANDINA B (PGB), PROSTAGLANDINA C (PGC), DERIVADOS DE PGA, PGB Y PGC, CONJUGADOS DE PGA Y DERIVADOS CONJUGADOS DE PGA, PARA REDUCIR LA PRESION INTRAOCULAR DEL OJO Y MANTENER REDUCIDA LA PRESION INTRAOCULAR. TAMBIEN SE PROPORCIONA UNA COMPOSICION PARA TRATAMIENTO TOPICO DE HIPERTENSION O GLAUCOMA EN EL OJO DE UN SUJETO, QUE COMPRNDE UNA CANTIDAD EFICAZ PARA REDUCIR LA PRESION INTRAOCULAR, DE UNA O MAS PROSTAGLANDINAS ELEGIDAS DEL GRUPO QUE CONSTA DE PGA, PGB Y PGC, DERIVADOS DE PGA, PGB Y PGC Y CONJUGADOS DE PGA Y UN SOPORTE OFTALMICAMENTE COMPATIBLE.
ES87103714T 1986-03-13 1987-03-13 Utilizacion de prostaglandinas a, b y c y derivados de las mismas, para el tratamiento de la hipertension ocular y glaucoma. Expired - Lifetime ES2053458T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US83905686A 1986-03-13 1986-03-13
US89238786A 1986-07-31 1986-07-31
US07/022,046 US4883819A (en) 1986-07-31 1987-03-05 Use of A, B and C prostaglandins and derivatives thereof to treat ocular hypertension and glaucoma

Publications (1)

Publication Number Publication Date
ES2053458T3 true ES2053458T3 (es) 1994-08-01

Family

ID=27361778

Family Applications (1)

Application Number Title Priority Date Filing Date
ES87103714T Expired - Lifetime ES2053458T3 (es) 1986-03-13 1987-03-13 Utilizacion de prostaglandinas a, b y c y derivados de las mismas, para el tratamiento de la hipertension ocular y glaucoma.

Country Status (4)

Country Link
EP (1) EP0242580B1 (es)
JP (1) JPH0643313B2 (es)
DE (1) DE3785602T2 (es)
ES (1) ES2053458T3 (es)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4824857A (en) * 1986-05-16 1989-04-25 Yasumasa Goh Use of prostaglandin D2 -active substances
EP0286903B2 (en) * 1987-04-03 2000-03-29 The Trustees Of Columbia University In The City Of New York Use of a prostaglandin in combination with an adrenergic blocking agent for reduction of intraocular pressure
US5166178B1 (en) * 1987-09-18 1998-07-21 R Tech Ueno Ltd Ocular hypotensive agents
US5212200A (en) * 1987-09-18 1993-05-18 R-Tech Ueno, Ltd. Ocular hypotensive agents
US5151444B1 (en) * 1987-09-18 1999-07-06 R Tech Ueno Ltd Ocular hypotensive agents
US6420422B1 (en) 1987-09-18 2002-07-16 Sucampo Pharmaceuticals, Inc. Ocular hypotensive agents
ATE108330T1 (de) * 1987-09-18 1994-07-15 R Tech Ueno Ltd Hypotensive okulare mittel.
US5321128A (en) * 1988-09-06 1994-06-14 Kabi Pharmacia Ab Prostaglandin derivatives for the treatment of glaucoma or ocular hypertension
JP2721414B2 (ja) * 1988-09-06 1998-03-04 フアーマシア・アンド・アツプジヨン・アー・ベー 縁内障または眼圧亢進の治療のためのプロスタグランジン誘導体
US5296504A (en) * 1988-09-06 1994-03-22 Kabi Pharmacia Prostaglandin derivatives for the treatment of glaucoma or ocular hypertension
US6187813B1 (en) 1990-04-10 2001-02-13 Pharmacia & Upjohn Aktiebolag Prostaglandin derivatives for the treatment of glaucoma or ocular hypertension
EP0471856B1 (en) * 1990-03-08 1995-03-22 Shionogi & Co., Ltd. 15-deoxyprostaglandin derivative
EP0458588B1 (en) * 1990-05-22 1994-11-30 R-Tech Ueno Ltd. Treatment of ocular hypertension with a synergistic combination for ocular administration
ES2069823T3 (es) * 1990-05-22 1995-05-16 R Tech Ueno Ltd Tratamiento de la hipertension ocular con una combinacion sinergica ocular.
EP0458590B1 (en) * 1990-05-22 1996-01-10 R-Tech Ueno Ltd. Treatment of ocular hypertention with a synergistic combination
US5270049A (en) * 1990-11-09 1993-12-14 Allergan, Inc. 2-decarboxyl-2-aminoalkyl-prostaglandins as ocular hypotensives
TW210287B (es) * 1991-03-01 1993-08-01 Kabushikaisha Ueno Seiyaku Oyo Kenkyujo
US5468778A (en) * 1992-09-24 1995-11-21 Allergan, Inc. Method of lowering intraocular pressure by administering a pharmaceutical composition containing 7-(5-substituted cyclopentyl) and 7-(5-substituted-cyclopentenyl) 5-heptenoic acids and derivatives
US5385945A (en) * 1992-10-21 1995-01-31 Allergan, Inc. 7-(5-substituted cyclopentyl) and (5-substituted cyclopentenyl) heptyl alcohols, heptylamines and heptanoic acid amides, and method of lowering intraocular pressure in the eye of a mammal by administration of these novel compounds
JP2769294B2 (ja) * 1993-12-15 1998-06-25 アルコン ラボラトリーズ インコーポレイテッド 局所的眼薬組成物及びそのためのプロスタグランジン化合物
SE9403158D0 (sv) * 1994-09-21 1994-09-21 Pharmacia Ab New use of prostaglandins
SE9403160D0 (sv) * 1994-09-21 1994-09-21 Pharmacia Ab Method and means for prevention and treatment of secondary cataract
SE9900672D0 (sv) * 1999-02-25 1999-02-25 Synphora Ab Method and composition for prevention of scar formation in glaucoma filtration bleb and drainage fistula
US20040058313A1 (en) * 2002-04-24 2004-03-25 Abreu Marcio Marc Compositions, targets, methods and devices for the therapy of ocular and periocular disorders

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3986764A (en) * 1975-03-31 1976-10-19 Gte Automatic Electric Laboratories Incorporated Panel for supporting a pair of elongated mating connectors and selectively locking them together
US4599353A (en) * 1982-05-03 1986-07-08 The Trustees Of Columbia University In The City Of New York Use of eicosanoids and their derivatives for treatment of ocular hypertension and glaucoma

Also Published As

Publication number Publication date
JPS6366122A (ja) 1988-03-24
DE3785602T2 (de) 1993-09-02
EP0242580B1 (en) 1993-04-28
EP0242580A2 (en) 1987-10-28
DE3785602D1 (de) 1993-06-03
EP0242580A3 (en) 1990-05-02
JPH0643313B2 (ja) 1994-06-08

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