IT1148189B - 1-(p-2-isopropossietossimetil-fenossi)-3-isopropilammino-propan-2-olo e suoi sali per l'abbassamento della pressione endooculare e preparati oftalmici che li contengono - Google Patents

1-(p-2-isopropossietossimetil-fenossi)-3-isopropilammino-propan-2-olo e suoi sali per l'abbassamento della pressione endooculare e preparati oftalmici che li contengono

Info

Publication number
IT1148189B
IT1148189B IT48712/82A IT4871282A IT1148189B IT 1148189 B IT1148189 B IT 1148189B IT 48712/82 A IT48712/82 A IT 48712/82A IT 4871282 A IT4871282 A IT 4871282A IT 1148189 B IT1148189 B IT 1148189B
Authority
IT
Italy
Prior art keywords
propan
salts
isopropossietossimetil
isopropilamino
fenossi
Prior art date
Application number
IT48712/82A
Other languages
English (en)
Other versions
IT8248712A0 (it
Inventor
Jurgen Harting
Andreas Fuchs
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of IT8248712A0 publication Critical patent/IT8248712A0/it
Application granted granted Critical
Publication of IT1148189B publication Critical patent/IT1148189B/it

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/28Compounds containing heavy metals
    • A61K31/305Mercury compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IT48712/82A 1981-06-30 1982-06-28 1-(p-2-isopropossietossimetil-fenossi)-3-isopropilammino-propan-2-olo e suoi sali per l'abbassamento della pressione endooculare e preparati oftalmici che li contengono IT1148189B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19813125636 DE3125636A1 (de) 1981-06-30 1981-06-30 1-(p-2-isopropoxyethoxymethyl-phenoxy)-3-isopropylamino-propan-2-ol zur senkung des augeninnendrucks und ophtalmikum, enthalten diese verbindung

Publications (2)

Publication Number Publication Date
IT8248712A0 IT8248712A0 (it) 1982-06-28
IT1148189B true IT1148189B (it) 1986-11-26

Family

ID=6135697

Family Applications (1)

Application Number Title Priority Date Filing Date
IT48712/82A IT1148189B (it) 1981-06-30 1982-06-28 1-(p-2-isopropossietossimetil-fenossi)-3-isopropilammino-propan-2-olo e suoi sali per l'abbassamento della pressione endooculare e preparati oftalmici che li contengono

Country Status (8)

Country Link
US (1) US4522829A (it)
EP (1) EP0068160B1 (it)
JP (1) JPS588047A (it)
AT (1) ATE23112T1 (it)
BE (1) BE893637A (it)
DE (2) DE3125636A1 (it)
IT (1) IT1148189B (it)
ZA (1) ZA824599B (it)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3151201A1 (de) * 1981-12-23 1983-07-28 Beiersdorf Ag, 2000 Hamburg Substituierte phenoxyalkanolamine und phenoxyalkanol-cycloalkylamine, verfahren zu ihrer herstellung, diese verbindungen enthaltende pharmazeutische zubereitungen und zwischenprodukte
IT1163107B (it) * 1983-02-15 1987-04-08 Simes Composizioni farmaceutiche e loro uso nel trattamento del glaucoma
ATE45724T1 (de) * 1985-12-24 1989-09-15 Merck & Co Inc Okuloselektive betablocker.
US4945182A (en) * 1985-12-24 1990-07-31 Merck & Co., Inc. Oculoselective beta-blockers
US4694022A (en) * 1986-12-24 1987-09-15 Alcon Laboratories, Inc. Fatty acid salts of betaxolol useful in the treatment of glaucoma
US5660851A (en) * 1989-12-26 1997-08-26 Yissum Research Development Company Of The Hebrew Univ. Of Jerusalem Ocular inserts
AU2009202969B1 (en) * 2009-07-23 2009-11-19 Allergan, Inc. Ketorolac tromethamine compositions for treating or preventing ocular pain
US7842714B2 (en) * 2008-03-03 2010-11-30 Allergan, Inc. Ketorolac tromethamine compositions for treating ocular pain
US9192571B2 (en) 2008-03-03 2015-11-24 Allergan, Inc. Ketorolac tromethamine compositions for treating or preventing ocular pain

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE384853B (sv) * 1972-04-04 1976-05-24 Haessle Ab Forfarande for framstellning av nya aminer
FR2330383A1 (fr) * 1975-11-06 1977-06-03 Synthelabo Nouveaux ethers de phenols substitues, leurs sels, leur preparation et les medicaments qui les renferment
JPS52154528A (en) * 1976-05-31 1977-12-22 Kaken Pharmaceut Co Ltd Remedy for glaucoma
DE2645710C2 (de) * 1976-10-09 1985-06-27 Merck Patent Gmbh, 6100 Darmstadt Phenoxy-amino-propanole, Verfahren zu ihrer Herstellung und pharmazeutische Zubereitung

Also Published As

Publication number Publication date
ZA824599B (en) 1983-10-26
ATE23112T1 (de) 1986-11-15
DE3125636A1 (de) 1983-01-13
JPS588047A (ja) 1983-01-18
IT8248712A0 (it) 1982-06-28
DE3273950D1 (en) 1986-12-04
EP0068160B1 (de) 1986-10-29
EP0068160A1 (de) 1983-01-05
US4522829A (en) 1985-06-11
BE893637A (fr) 1982-12-27

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Effective date: 19970628