DE69208478T2 - Amid derivate von vitamin d - Google Patents

Amid derivate von vitamin d

Info

Publication number
DE69208478T2
DE69208478T2 DE69208478T DE69208478T DE69208478T2 DE 69208478 T2 DE69208478 T2 DE 69208478T2 DE 69208478 T DE69208478 T DE 69208478T DE 69208478 T DE69208478 T DE 69208478T DE 69208478 T2 DE69208478 T2 DE 69208478T2
Authority
DE
Germany
Prior art keywords
vitamin
alpha
amid derivatives
amid
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69208478T
Other languages
English (en)
Other versions
DE69208478D1 (de
Inventor
Robert Hesse
Gaddam Reddy
Sundara Setty
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
RES INST MEDICINE CHEM
Original Assignee
RES INST MEDICINE CHEM
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB919123712A external-priority patent/GB9123712D0/en
Priority claimed from GB929209658A external-priority patent/GB9209658D0/en
Application filed by RES INST MEDICINE CHEM filed Critical RES INST MEDICINE CHEM
Application granted granted Critical
Publication of DE69208478D1 publication Critical patent/DE69208478D1/de
Publication of DE69208478T2 publication Critical patent/DE69208478T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Nutrition Science (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
DE69208478T 1991-11-07 1992-11-06 Amid derivate von vitamin d Expired - Fee Related DE69208478T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB919123712A GB9123712D0 (en) 1991-11-07 1991-11-07 Chemical compounds
GB929209658A GB9209658D0 (en) 1992-05-05 1992-05-05 Chemical compounds
PCT/EP1992/002577 WO1993009093A1 (en) 1991-11-07 1992-11-06 Vitamin d amide derivatives

Publications (2)

Publication Number Publication Date
DE69208478D1 DE69208478D1 (de) 1996-03-28
DE69208478T2 true DE69208478T2 (de) 1996-09-05

Family

ID=26299825

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69208478T Expired - Fee Related DE69208478T2 (de) 1991-11-07 1992-11-06 Amid derivate von vitamin d

Country Status (20)

Country Link
US (2) US5494905A (de)
EP (1) EP0614455B1 (de)
JP (1) JP3282811B2 (de)
KR (1) KR100271461B1 (de)
AT (1) ATE134366T1 (de)
AU (1) AU664213B2 (de)
CA (1) CA2121678C (de)
CZ (1) CZ288031B6 (de)
DE (1) DE69208478T2 (de)
DK (1) DK0614455T3 (de)
ES (1) ES2083771T3 (de)
FI (1) FI106119B (de)
GR (1) GR3019601T3 (de)
HU (1) HU221008B1 (de)
NO (1) NO305315B1 (de)
NZ (1) NZ245041A (de)
PL (1) PL171580B1 (de)
RU (1) RU2139276C1 (de)
SK (1) SK281302B6 (de)
WO (1) WO1993009093A1 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ245041A (en) * 1991-11-07 1995-03-28 Res Inst Medicine Chem Vitamin d analogues and pharmaceutical compositions
IL107185A (en) * 1992-10-06 1998-02-22 Schering Ag History of 52-carboxylic acid, processes for their preparation and pharmaceutical preparations containing them
US5662604A (en) * 1993-02-12 1997-09-02 Asahi Kasei Kogyo Kabushiki Kaisha Monitoring method of renal lesions without clinical signs
GB9309422D0 (en) * 1993-05-07 1993-06-23 Res Inst Medicine Chem Chemical compounds
GB9325415D0 (en) * 1993-12-13 1994-02-16 Res Inst Medicine Chem Chemical compounds
GB9405715D0 (en) * 1994-03-23 1994-05-11 Res Inst Medicine Chem Chemical compounds
US5661141A (en) * 1995-03-27 1997-08-26 Petrow; Vladimir 19-oxygenated steroids as therapeutic agents
US5678570A (en) * 1995-04-14 1997-10-21 The University Of North Carolina At Chapel Hill Method of treating cardiac arrest
US5696103A (en) * 1995-11-17 1997-12-09 Syntex (U.S.A.) Inc. Method for treating osteoporosis
DE19619036A1 (de) * 1996-04-30 1997-11-13 Schering Ag Neue Vitamin D-Derivate mit carbo- oder heterocyclischen Substituenten an C-25, Verfahren zu ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln
US6043385A (en) * 1997-12-16 2000-03-28 Hoffman-La Roche Inc. Vitamin D derivatives
GB9804861D0 (en) * 1998-03-06 1998-04-29 Res Inst Medicine Chem Chemical compounds
AU758792B2 (en) * 1998-10-23 2003-03-27 Teijin Limited Vitamin D3 derivatives and remedies for inflammatory respiratory diseases containing the same
DE19935771A1 (de) * 1999-07-23 2001-02-01 Schering Ag Neue Vitamin D-Derivate mit cyclischen Substrukturen in den Seitenketten, Verfahren und Zwischenprodukte zu ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln
ATE294585T1 (de) 1999-09-29 2005-05-15 Colotech As Vorbeugung von kolorektalkrebs
US6703380B2 (en) 1999-09-29 2004-03-09 Colotech A/S Prevention of cancer
AU1153201A (en) * 1999-10-25 2001-05-08 Strakan Limited Uses of 1,25-dihydroxy-5,6-trans vitamin D compounds and derivatives thereof
IL153395A0 (en) 2000-06-15 2003-07-06 Chugai Pharmaceutical Co Ltd Vitamin d derivatives
AU2005303773A1 (en) 2004-11-12 2006-05-18 Bioxell Spa Combined use of vitamin D derivatives and anti-proliferative agents for treating bladder cancer
EP2018366A4 (de) * 2006-05-16 2010-08-04 Univ Mcgill Hybridmoleküle mit gemischten vitamin-d-rezeptor-agonismus und histondeacetylase hemmenden eigenschaften
WO2009117831A1 (en) * 2008-03-27 2009-10-01 The Royal Institution For The Advancement Of Learning/Mcgill University Hybrid molecules having mixed vitamin d receptor agonism and histone deacetylase inhibitory properties
WO2012158794A1 (en) 2011-05-17 2012-11-22 Wisconsin Alumni Research Foundation N-cyclopropyl-(20r)-2-methylene-19,26,27-trinor-25-aza-vitamin d analogs and their uses
IL300818A (en) * 2020-09-15 2023-04-01 Teijin Pharma Ltd A vitamin D derivative with a cyclic amine in the side chain

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4217288A (en) * 1977-03-24 1980-08-12 Wisconsin Alumni Research Foundation Anti-vitamin D compounds
FR2426044A2 (fr) * 1978-05-19 1979-12-14 Wisconsin Research Foundation Derives de la vitamine d3 ayant une activite anti-vitamine d
US5206230A (en) * 1991-06-05 1993-04-27 Daikin Industries, Ltd. Fluorine-containing vitamin D3 analogues and pharmaceutical composition containing the same
NZ245041A (en) * 1991-11-07 1995-03-28 Res Inst Medicine Chem Vitamin d analogues and pharmaceutical compositions

Also Published As

Publication number Publication date
AU664213B2 (en) 1995-11-09
DK0614455T3 (da) 1996-03-18
HU9401372D0 (en) 1994-08-29
RU2139276C1 (ru) 1999-10-10
CZ288031B6 (cs) 2001-04-11
EP0614455A1 (de) 1994-09-14
FI106119B (fi) 2000-11-30
CA2121678A1 (en) 1993-05-13
ES2083771T3 (es) 1996-04-16
SK52294A3 (en) 1994-11-09
PL171580B1 (pl) 1997-05-30
NO941683L (de) 1994-06-27
NZ245041A (en) 1995-03-28
US5494905A (en) 1996-02-27
FI942114A (fi) 1994-05-06
NO305315B1 (no) 1999-05-10
FI942114A0 (fi) 1994-05-06
WO1993009093A1 (en) 1993-05-13
JP3282811B2 (ja) 2002-05-20
SK281302B6 (sk) 2001-02-12
HUT67140A (en) 1995-02-28
CZ111294A3 (en) 1995-03-15
HU221008B1 (hu) 2002-07-29
CA2121678C (en) 2005-03-15
GR3019601T3 (en) 1996-07-31
KR100271461B1 (ko) 2000-11-15
ATE134366T1 (de) 1996-03-15
DE69208478D1 (de) 1996-03-28
EP0614455B1 (de) 1996-02-21
NO941683D0 (no) 1994-05-06
AU2901492A (en) 1993-06-07
US5686435A (en) 1997-11-11
JPH07502499A (ja) 1995-03-16

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: PFENNING MEINIG & PARTNER GBR, 80339 MUENCHEN

8339 Ceased/non-payment of the annual fee