FI955316A - Vitamiini D:n amidijohdannaisia - Google Patents

Vitamiini D:n amidijohdannaisia Download PDF

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Publication number
FI955316A
FI955316A FI955316A FI955316A FI955316A FI 955316 A FI955316 A FI 955316A FI 955316 A FI955316 A FI 955316A FI 955316 A FI955316 A FI 955316A FI 955316 A FI955316 A FI 955316A
Authority
FI
Finland
Prior art keywords
group
pct
alpha
vitamin
sec
Prior art date
Application number
FI955316A
Other languages
English (en)
Swedish (sv)
Other versions
FI955316A0 (fi
FI112361B (fi
Inventor
Robert Henry Hesse
Sundara Katugam Srinivas Setty
Malathi Ramgopal
Original Assignee
Res Inst Medicine Chem
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Res Inst Medicine Chem filed Critical Res Inst Medicine Chem
Publication of FI955316A0 publication Critical patent/FI955316A0/fi
Publication of FI955316A publication Critical patent/FI955316A/fi
Application granted granted Critical
Publication of FI112361B publication Critical patent/FI112361B/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
    • A61P5/12—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH for decreasing, blocking or antagonising the activity of the posterior pituitary hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/215—Radicals derived from nitrogen analogues of carbonic acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FI955316A 1993-05-07 1995-11-06 Menetelmä terapeuttisesti käyttökelpoisten D-vitamiinin johdannaisten valmistamiseksi FI112361B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB9309422 1993-05-07
GB939309422A GB9309422D0 (en) 1993-05-07 1993-05-07 Chemical compounds
PCT/GB1994/000975 WO1994026707A1 (en) 1993-05-07 1994-05-06 Vitamin d amide derivatives
GB9400975 1994-05-06

Publications (3)

Publication Number Publication Date
FI955316A0 FI955316A0 (fi) 1995-11-06
FI955316A true FI955316A (fi) 1995-12-22
FI112361B FI112361B (fi) 2003-11-28

Family

ID=10735089

Family Applications (1)

Application Number Title Priority Date Filing Date
FI955316A FI112361B (fi) 1993-05-07 1995-11-06 Menetelmä terapeuttisesti käyttökelpoisten D-vitamiinin johdannaisten valmistamiseksi

Country Status (20)

Country Link
US (1) US5756733A (fi)
EP (1) EP0696275B1 (fi)
JP (1) JP3703099B2 (fi)
KR (1) KR100321414B1 (fi)
CN (1) CN1093852C (fi)
AT (1) ATE169617T1 (fi)
AU (1) AU678246B2 (fi)
CA (1) CA2162272A1 (fi)
CZ (1) CZ291238B6 (fi)
DE (1) DE69412476T2 (fi)
DK (1) DK0696275T3 (fi)
ES (1) ES2122275T3 (fi)
FI (1) FI112361B (fi)
GB (1) GB9309422D0 (fi)
HU (1) HUT74165A (fi)
IL (1) IL109595A (fi)
NO (1) NO309187B1 (fi)
NZ (1) NZ265665A (fi)
WO (1) WO1994026707A1 (fi)
ZA (1) ZA943162B (fi)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9405715D0 (en) * 1994-03-23 1994-05-11 Res Inst Medicine Chem Chemical compounds
DE69523182T2 (de) * 1995-06-06 2002-02-07 Pfizer Substituierte n-(indol-2-carbonyl)-glycinamide und derivate als glycogen phosphorylase inhibitoren
DE19619036A1 (de) 1996-04-30 1997-11-13 Schering Ag Neue Vitamin D-Derivate mit carbo- oder heterocyclischen Substituenten an C-25, Verfahren zu ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln
GB9623569D0 (en) * 1996-11-13 1997-01-08 Immunodiagnostic Systems Ltd Vitamin D immumoassay systems
US6043385A (en) * 1997-12-16 2000-03-28 Hoffman-La Roche Inc. Vitamin D derivatives
GB9804861D0 (en) * 1998-03-06 1998-04-29 Res Inst Medicine Chem Chemical compounds
KR100676106B1 (ko) * 1998-10-23 2007-02-28 데이진 가부시키가이샤 비타민 ｄ3 유도체 및 그것을 사용하는 염증성 호흡기질환 치료제
PT1666026E (pt) * 1999-02-08 2012-03-15 Intarcia Therapeutics Inc Veículos viscosos não aquosos biocompatíveis monofásicos e métodos para a preparação dos mesmos
DE19935771A1 (de) * 1999-07-23 2001-02-01 Schering Ag Neue Vitamin D-Derivate mit cyclischen Substrukturen in den Seitenketten, Verfahren und Zwischenprodukte zu ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln
EP1220676B1 (en) 1999-09-29 2005-05-04 Colotech A/S Prevention of colorectal cancer
US6703380B2 (en) 1999-09-29 2004-03-09 Colotech A/S Prevention of cancer
US6989377B2 (en) 1999-12-21 2006-01-24 Wisconsin Alumni Research Foundation Treating vitamin D responsive diseases
US6358939B1 (en) 1999-12-21 2002-03-19 Northern Lights Pharmaceuticals, Llc Use of biologically active vitamin D compounds for the prevention and treatment of inflammatory bowel disease
ES2364623T3 (es) * 2000-06-15 2011-09-08 Chugai Seiyaku Kabushiki Kaisha Derivados de vitamina d que poseen un átomo 22-oxa o 22-tia, una cadena lateral c17 sustituida con un grupo ácido, éster o amida y un enlace doble 16(17).
WO2001096293A1 (fr) * 2000-06-15 2001-12-20 Chugai Seiyaku Kabushiki Kaisha Derives de vitamine d
US6277877B1 (en) 2000-08-15 2001-08-21 Pfizer, Inc. Substituted n-(indole-2-carbonyl)glycinamides and derivates as glycogen phosphorylase inhibitors
JP4527408B2 (ja) * 2002-04-26 2010-08-18 シェーリング コーポレイション ムスカリン性アンタゴニスト
KR20160112018A (ko) 2006-06-02 2016-09-27 니뽄 신야쿠 가부시키가이샤 9,10-세코프레그난 유도체 및 의약
WO2009117831A1 (en) * 2008-03-27 2009-10-01 The Royal Institution For The Advancement Of Learning/Mcgill University Hybrid molecules having mixed vitamin d receptor agonism and histone deacetylase inhibitory properties
CA2981549A1 (en) * 2009-01-27 2010-08-05 Berg Llc Vitamin d3 and analogs thereof for alleviating side effects associated with chemotherapy
SG10201404883YA (en) 2009-08-14 2014-10-30 Berg Llc Vitamin d3 and analogs thereof for treating alopecia
US9290447B2 (en) 2011-05-03 2016-03-22 Wisconsin Alumni Research Foundation (20R) and (20S)-24-(p-toluenesulfonyloxy)-25,26,27-trinorvitamin D3 analogs and their uses
WO2012158794A1 (en) 2011-05-17 2012-11-22 Wisconsin Alumni Research Foundation N-cyclopropyl-(20r)-2-methylene-19,26,27-trinor-25-aza-vitamin d analogs and their uses
AU2014274099A1 (en) 2013-05-29 2015-12-24 Berg Llc Preventing or mitigating chemotherapy induced alopecia using vitamin D
US9338493B2 (en) 2014-06-30 2016-05-10 Apple Inc. Intelligent automated assistant for TV user interactions
US10548908B2 (en) 2016-09-15 2020-02-04 Nostopharma, LLC Compositions and methods for preventing and treating heterotopic ossification and pathologic calcification

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8929059D0 (en) * 1989-12-22 1990-02-28 Leo Pharm Prod Ltd Chemical compounds
CZ288031B6 (cs) * 1991-11-07 2001-04-11 Research Institute For Medicine And Chemistry Amidové deriváty vitaminu D, způsob výroby a farmaceutické prostředky s jejich obsahem

Also Published As

Publication number Publication date
CN1093852C (zh) 2002-11-06
GB9309422D0 (en) 1993-06-23
IL109595A0 (en) 1994-08-26
NO954426D0 (no) 1995-11-06
ZA943162B (en) 1995-04-13
EP0696275B1 (en) 1998-08-12
NZ265665A (en) 1997-05-26
CA2162272A1 (en) 1994-11-24
NO954426L (no) 1996-01-08
AU6683294A (en) 1994-12-12
DK0696275T3 (da) 1998-11-09
HUT74165A (en) 1996-11-28
ES2122275T3 (es) 1998-12-16
WO1994026707A1 (en) 1994-11-24
AU678246B2 (en) 1997-05-22
US5756733A (en) 1998-05-26
CN1125436A (zh) 1996-06-26
FI955316A0 (fi) 1995-11-06
EP0696275A1 (en) 1996-02-14
HU9503190D0 (en) 1996-01-29
JP3703099B2 (ja) 2005-10-05
DE69412476T2 (de) 1999-03-11
CZ290395A3 (en) 1996-06-12
NO309187B1 (no) 2000-12-27
CZ291238B6 (cs) 2003-01-15
JPH08509971A (ja) 1996-10-22
IL109595A (en) 1999-04-11
DE69412476D1 (de) 1998-09-17
FI112361B (fi) 2003-11-28
ATE169617T1 (de) 1998-08-15
KR100321414B1 (ko) 2002-12-05

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