DK0585440T3 - 2-amino-1,2,3,4-tetrahydronaphtalen-derivater med virkning på det cardiovasculære system fremgangsmåde til fremstilling af disse og farmaceutiske præparater indeholdende disse - Google Patents

2-amino-1,2,3,4-tetrahydronaphtalen-derivater med virkning på det cardiovasculære system fremgangsmåde til fremstilling af disse og farmaceutiske præparater indeholdende disse

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Publication number
DK0585440T3
DK0585440T3 DK93906515.7T DK93906515T DK0585440T3 DK 0585440 T3 DK0585440 T3 DK 0585440T3 DK 93906515 T DK93906515 T DK 93906515T DK 0585440 T3 DK0585440 T3 DK 0585440T3
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DK
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Prior art keywords
amino
preparation
effect
pharmaceutical compositions
compositions containing
Prior art date
Application number
DK93906515.7T
Other languages
Danish (da)
English (en)
Inventor
Cesare Casagrande
Francesco Santangelo
Giorgio Bertolini
Francesco Marchini
Stefania Montanari
Claudio Semeraro
Original Assignee
Zambon Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zambon Spa filed Critical Zambon Spa
Application granted granted Critical
Publication of DK0585440T3 publication Critical patent/DK0585440T3/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C219/26—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
    • C07C217/14—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring
    • C07C217/18—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
    • C07C217/20—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted by halogen atoms, by trihalomethyl, nitro or nitroso groups, or by singly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/20—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by nitrogen atoms not being part of nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/40—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings
    • C07C271/42—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/44—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK93906515.7T 1992-03-17 1993-03-13 2-amino-1,2,3,4-tetrahydronaphtalen-derivater med virkning på det cardiovasculære system fremgangsmåde til fremstilling af disse og farmaceutiske præparater indeholdende disse DK0585440T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI920608A IT1254521B (it) 1992-03-17 1992-03-17 Derivati della 2-ammino-tetralina attivi sul sistema cardiovascolare

Publications (1)

Publication Number Publication Date
DK0585440T3 true DK0585440T3 (da) 1996-06-10

Family

ID=11362451

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93906515.7T DK0585440T3 (da) 1992-03-17 1993-03-13 2-amino-1,2,3,4-tetrahydronaphtalen-derivater med virkning på det cardiovasculære system fremgangsmåde til fremstilling af disse og farmaceutiske præparater indeholdende disse

Country Status (20)

Country Link
US (2) US5407956A (fi)
EP (1) EP0585440B1 (fi)
JP (1) JP3231775B2 (fi)
KR (1) KR100283945B1 (fi)
AT (1) ATE137737T1 (fi)
CA (1) CA2102490C (fi)
DE (1) DE69302544T2 (fi)
DK (1) DK0585440T3 (fi)
ES (1) ES2087729T3 (fi)
FI (1) FI935066A (fi)
GR (1) GR3020419T3 (fi)
HU (2) HUT68936A (fi)
IT (1) IT1254521B (fi)
MD (1) MD1449G2 (fi)
NO (1) NO180230C (fi)
NZ (1) NZ249845A (fi)
OA (1) OA09843A (fi)
PL (2) PL172056B1 (fi)
RU (1) RU2120435C1 (fi)
WO (1) WO1993019036A1 (fi)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1271411B (it) * 1993-09-14 1997-05-28 Zambon Spa Derivati del 2-ammino-1,2,3,4-tetraidro-naftalene attivi sul sistema cardiovascolare
IT1274673B (it) * 1994-04-14 1997-07-24 Zambon Spa Derivati dell'acido fosfonico utili nel trattamento delle malattie car.iovascolari
IT1270260B (it) * 1994-06-21 1997-04-29 Zambon Spa Derivati dell'acido fosfonico ad attivita' inibitrice delle metallopeptidasi
IT1271009B (it) * 1994-09-13 1997-05-26 Zambon Spa Derivati del benzopirano e del benzotiopirano attivi sul sistema cardiovascolare
IT1271008B (it) * 1994-09-13 1997-05-26 Zambon Spa Derivati del 2-ammino-1,2,3,4-tetraidro-naftalene attivi sul sistema cardiovascolare
IT1271007B (it) * 1994-09-13 1997-05-26 Zambon Spa Derivati del 2-ammino-1,2,3,4-tetraidronaftalene attivi sul sistema cardiovascolare
IT1273455B (it) * 1995-01-27 1997-07-08 Zambon Spa Derivati tiolici ad attivita' inibitrice delle metallopeptidasi
IT1276710B1 (it) * 1995-06-14 1997-11-03 Zambon Spa Derivati dell'acido fosfinico ad attivita' inibitrice delle metallopeptidasi
GB9625455D0 (en) * 1996-12-07 1997-01-22 Glaxo Group Ltd Process for resolving mixtures of carbocyclic steroisomers
IT1289980B1 (it) * 1997-02-26 1998-10-19 Zambon Spa Derivati idrossimetilici del 2-ammino-1,2,3,4-tetraidronaftalene attivi in campo cardiovascolare
MX2011005979A (es) * 2008-12-09 2011-06-27 Interquim Sa Procedimiento de obtencion de (6s)-(-)-5,6,7,8-tetrahidro-6-[propi l-(2-tienil)etil]amino-1-naftol(rotigotina).

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3263531D1 (en) * 1981-08-05 1985-06-20 Fisons Plc Amine derivatives, processes for their production and pharmaceutical compositions containing them
DE3484048D1 (de) * 1983-10-25 1991-03-07 Fisons Plc Phenylethylamine, verfahren zu deren herstellung und diese enthaltende zusammensetzungen.
IT1224405B (it) * 1987-12-23 1990-10-04 Simes Composti attivi sul sistema cardiovascolare

Also Published As

Publication number Publication date
RU2120435C1 (ru) 1998-10-20
WO1993019036A1 (en) 1993-09-30
PL171844B1 (pl) 1997-06-30
MD960271A (en) 1997-09-30
ATE137737T1 (de) 1996-05-15
JPH06507920A (ja) 1994-09-08
DE69302544T2 (de) 1996-09-19
NZ249845A (en) 1996-03-26
MD1449F1 (en) 2000-04-30
OA09843A (en) 1994-08-15
US5407956A (en) 1995-04-18
AU650201B2 (en) 1994-06-09
NO180230B (no) 1996-12-02
ES2087729T3 (es) 1996-07-16
PL172056B1 (pl) 1997-07-31
FI935066A0 (fi) 1993-11-16
IT1254521B (it) 1995-09-25
ITMI920608A0 (it) 1992-03-17
ITMI920608A1 (it) 1993-09-17
JP3231775B2 (ja) 2001-11-26
NO180230C (no) 1997-03-12
GR3020419T3 (en) 1996-10-31
NO934160L (no) 1993-11-17
EP0585440B1 (en) 1996-05-08
KR100283945B1 (ko) 2001-03-02
MD1449G2 (ro) 2000-12-31
NO934160D0 (no) 1993-11-17
CA2102490C (en) 2004-06-08
HU211517A9 (en) 1995-11-28
CA2102490A1 (en) 1993-09-18
EP0585440A1 (en) 1994-03-09
AU3747893A (en) 1993-10-21
FI935066A (fi) 1993-11-16
US5451608A (en) 1995-09-19
HUT68936A (en) 1995-08-28
DE69302544D1 (de) 1996-06-13

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