NO892499L - 2,5,6,7-tetranor-4,8-inter-m-fenylen pgi2 derivater, fremgangsmaate for fremstilling av disse, og anvendelse derav. - Google Patents

2,5,6,7-tetranor-4,8-inter-m-fenylen pgi2 derivater, fremgangsmaate for fremstilling av disse, og anvendelse derav.

Info

Publication number
NO892499L
NO892499L NO89892499A NO892499A NO892499L NO 892499 L NO892499 L NO 892499L NO 89892499 A NO89892499 A NO 89892499A NO 892499 A NO892499 A NO 892499A NO 892499 L NO892499 L NO 892499L
Authority
NO
Norway
Prior art keywords
tetranor
inter
phenyl
procedure
preparation
Prior art date
Application number
NO89892499A
Other languages
English (en)
Other versions
NO174668C (no
NO892499D0 (no
NO174668B (no
Inventor
Kiyotaka Ohno
Toshiya Takahashi
Atsushi Ohtake
Hisanori Wakita
Shintaro Nishio
Original Assignee
Toray Industries
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toray Industries filed Critical Toray Industries
Publication of NO892499D0 publication Critical patent/NO892499D0/no
Publication of NO892499L publication Critical patent/NO892499L/no
Publication of NO174668B publication Critical patent/NO174668B/no
Publication of NO174668C publication Critical patent/NO174668C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
NO892499A 1987-10-16 1989-06-15 Analogifremgangsmåte for fremstilling av terapeutisk aktive 2,5,6,7 tetranor-4,8-inter-m-fenylen PGI2 derivater NO174668C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP26202187 1987-10-16
PCT/JP1988/001048 WO1989003387A1 (en) 1987-10-16 1988-10-14 2,5,6,7-TETRANOR-4,8-INTER-m-PHENYLENE PGI2 DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND USE THEREOF

Publications (4)

Publication Number Publication Date
NO892499D0 NO892499D0 (no) 1989-06-15
NO892499L true NO892499L (no) 1989-08-16
NO174668B NO174668B (no) 1994-03-07
NO174668C NO174668C (no) 1994-06-15

Family

ID=17369918

Family Applications (1)

Application Number Title Priority Date Filing Date
NO892499A NO174668C (no) 1987-10-16 1989-06-15 Analogifremgangsmåte for fremstilling av terapeutisk aktive 2,5,6,7 tetranor-4,8-inter-m-fenylen PGI2 derivater

Country Status (8)

Country Link
US (1) US5401768A (no)
EP (1) EP0365678B1 (no)
KR (1) KR960016541B1 (no)
DE (1) DE3886936T2 (no)
DK (1) DK296289A (no)
FI (1) FI102066B (no)
NO (1) NO174668C (no)
WO (1) WO1989003387A1 (no)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5589615A (en) * 1988-10-14 1996-12-31 Plant Genetic Systems N.V. Process for the production of transgenic plants with increased nutritional value via the expression of modified 2S storage albumins
ES2060944T3 (es) * 1989-03-14 1994-12-01 Toray Industries Derivados de 2,5,6,7-tetranor-4,8-inter-m-fenileno de pgi2 (prostaglandina i2).
JP3209427B2 (ja) * 1992-02-07 2001-09-17 科研製薬株式会社 創傷または痔疾治療剤
WO1997017974A1 (fr) * 1995-11-14 1997-05-22 Toray Industries, Inc. Depresseur oculaire
EP1016408B1 (en) * 1997-09-16 2006-04-19 Toray Industries, Inc. Novel paharmaceutical use of c-c chemokine production inhibitors
WO1999013881A1 (fr) * 1997-09-17 1999-03-25 Toray Industries, Inc. Agent de maturation cervical
WO2000024727A1 (fr) * 1998-10-23 2000-05-04 Toray Industries, Inc. DERIVE PGI2 DE 5,6,7-TRINOR-4,8-INTER-m-PHENYLENE ET MEDICAMENTS CONTENANT LEDIT DERIVE
CA2382759A1 (en) 1999-08-05 2001-02-15 Teijin Limited Agent for the remedy of neural damage having a nitrogen-containing compound as the active ingredient
CN106748951B (zh) 2012-07-19 2020-07-24 开曼化学股份有限公司 作为在治疗ep4介导的疾病和病状中使用的ep4受体选择性激动剂的二氟内酰胺化合物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5732277A (en) * 1980-08-05 1982-02-20 Toray Ind Inc 5,6,7-trinor-4,8-inter-m-phenylene pgi2 derivative
JPS57144276A (en) * 1981-03-03 1982-09-06 Toray Ind Inc 5,6,7-trinor-4,8-inter-m-phenylene pgi2 derivative
US4880939A (en) * 1986-12-11 1989-11-14 Toray Industries 2,5,6,7-tetranor-18,18,19,19-tetradehydro-4,8-inter-m-phenylene PGI2 derivatives
IL81215A (en) * 1987-01-09 1990-11-29 Israel Defence Two axis rate gyroscope

Also Published As

Publication number Publication date
DK296289D0 (da) 1989-06-15
FI102066B1 (fi) 1998-10-15
EP0365678B1 (en) 1994-01-05
EP0365678A1 (en) 1990-05-02
US5401768A (en) 1995-03-28
WO1989003387A1 (en) 1989-04-20
NO174668C (no) 1994-06-15
FI892949A0 (fi) 1989-06-15
FI102066B (fi) 1998-10-15
DK296289A (da) 1989-08-01
KR960016541B1 (en) 1996-12-14
NO892499D0 (no) 1989-06-15
KR890701576A (ko) 1989-12-21
FI892949A (fi) 1989-06-15
DE3886936T2 (de) 1994-04-28
DE3886936D1 (de) 1994-02-17
NO174668B (no) 1994-03-07
EP0365678A4 (en) 1990-02-20

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Free format text: LAPSED IN APRIL 2001