FI102066B1 - Menetelmä farmakologisesti aktiivisen 2,5,6,7-tetranor-4,8-inter-m-fenyleeni-PGI2-johdannaisen valmistamiseksi sekä välituote - Google Patents

Menetelmä farmakologisesti aktiivisen 2,5,6,7-tetranor-4,8-inter-m-fenyleeni-PGI2-johdannaisen valmistamiseksi sekä välituote

Info

Publication number
FI102066B1
FI102066B1 FI892949A FI892949A FI102066B1 FI 102066 B1 FI102066 B1 FI 102066B1 FI 892949 A FI892949 A FI 892949A FI 892949 A FI892949 A FI 892949A FI 102066 B1 FI102066 B1 FI 102066B1
Authority
FI
Finland
Prior art keywords
tetranor
inter
preparation
pharmacologically active
phenylene pgi2
Prior art date
Application number
FI892949A
Other languages
English (en)
Swedish (sv)
Other versions
FI102066B (fi
FI892949A0 (fi
FI892949A (fi
Inventor
Kiyotaka Ohno
Toshiya Takahashi
Atsushi Ohtake
Hisanori Wakita
Shintaro Nishio
Original Assignee
Toray Industries
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toray Industries filed Critical Toray Industries
Publication of FI892949A0 publication Critical patent/FI892949A0/fi
Publication of FI892949A publication Critical patent/FI892949A/fi
Application granted granted Critical
Publication of FI102066B publication Critical patent/FI102066B/fi
Publication of FI102066B1 publication Critical patent/FI102066B1/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
FI892949A 1987-10-16 1989-06-15 Menetelmä farmakologisesti aktiivisen 2,5,6,7-tetranor-4,8-inter-m-fenyleeni-PGI2-johdannaisen valmistamiseksi sekä välituote FI102066B1 (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP26202187 1987-10-16
JP26202187 1987-10-16
JP8801048 1988-10-14
PCT/JP1988/001048 WO1989003387A1 (en) 1987-10-16 1988-10-14 2,5,6,7-TETRANOR-4,8-INTER-m-PHENYLENE PGI2 DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND USE THEREOF

Publications (4)

Publication Number Publication Date
FI892949A0 FI892949A0 (fi) 1989-06-15
FI892949A FI892949A (fi) 1989-06-15
FI102066B FI102066B (fi) 1998-10-15
FI102066B1 true FI102066B1 (fi) 1998-10-15

Family

ID=17369918

Family Applications (1)

Application Number Title Priority Date Filing Date
FI892949A FI102066B1 (fi) 1987-10-16 1989-06-15 Menetelmä farmakologisesti aktiivisen 2,5,6,7-tetranor-4,8-inter-m-fenyleeni-PGI2-johdannaisen valmistamiseksi sekä välituote

Country Status (8)

Country Link
US (1) US5401768A (fi)
EP (1) EP0365678B1 (fi)
KR (1) KR960016541B1 (fi)
DE (1) DE3886936T2 (fi)
DK (1) DK296289A (fi)
FI (1) FI102066B1 (fi)
NO (1) NO174668C (fi)
WO (1) WO1989003387A1 (fi)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5589615A (en) * 1988-10-14 1996-12-31 Plant Genetic Systems N.V. Process for the production of transgenic plants with increased nutritional value via the expression of modified 2S storage albumins
EP0389162B1 (en) * 1989-03-14 1993-12-08 Toray Industries, Inc. 2,5,6,7-Tetranor-4,8-inter-m-phenylene PGI2 derivatives
EP0583482B1 (en) * 1992-02-07 1999-12-29 Kaken Pharmaceutical Co., Ltd. Remedy for wound or hemorrhoid
CA2210255A1 (en) * 1995-11-14 1997-05-22 Hajimu Kurumatani Agent for decreasing ocular tension
WO1999013880A1 (fr) * 1997-09-16 1999-03-25 Toray Industries, Inc. Inhibiteur de la production de chemokine c-c
CA2271475A1 (en) * 1997-09-17 1999-03-25 Masami Moriyama Cervical ripening agent
EP1044972A4 (en) * 1998-10-23 2003-03-12 Toray Industries 5,7,7-TRINOR-4,8-INTER-m-PHENYLENE PGI2 DERIVATIVE AND MEDICAMENTS CONTAINING SAID DERIVATIVE
ATE306256T1 (de) 1999-08-05 2005-10-15 Teijin Ltd Mittel zur besserung der neuropathie, die als wirkstoff stickstoffhaltige verbindungen enthalten
NZ704171A (en) 2012-07-19 2017-10-27 Cayman Chemical Co Inc Difluorolactam compositions for ep4-mediated osteo related diseases and conditions

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5732277A (en) * 1980-08-05 1982-02-20 Toray Ind Inc 5,6,7-trinor-4,8-inter-m-phenylene pgi2 derivative
JPS57144276A (en) * 1981-03-03 1982-09-06 Toray Ind Inc 5,6,7-trinor-4,8-inter-m-phenylene pgi2 derivative
US4880939A (en) * 1986-12-11 1989-11-14 Toray Industries 2,5,6,7-tetranor-18,18,19,19-tetradehydro-4,8-inter-m-phenylene PGI2 derivatives
IL81215A (en) * 1987-01-09 1990-11-29 Israel Defence Two axis rate gyroscope

Also Published As

Publication number Publication date
WO1989003387A1 (en) 1989-04-20
DK296289A (da) 1989-08-01
NO892499D0 (no) 1989-06-15
KR890701576A (ko) 1989-12-21
DK296289D0 (da) 1989-06-15
EP0365678A1 (en) 1990-05-02
NO174668C (no) 1994-06-15
DE3886936D1 (de) 1994-02-17
EP0365678B1 (en) 1994-01-05
KR960016541B1 (en) 1996-12-14
FI102066B (fi) 1998-10-15
DE3886936T2 (de) 1994-04-28
EP0365678A4 (en) 1990-02-20
FI892949A0 (fi) 1989-06-15
FI892949A (fi) 1989-06-15
NO892499L (no) 1989-08-16
NO174668B (no) 1994-03-07
US5401768A (en) 1995-03-28

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Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: TORAY INDUSTRIES, INC.