ATE69609T1 - Cardiotonische imidazolylphenylpyrrol-2-one. - Google Patents
Cardiotonische imidazolylphenylpyrrol-2-one.Info
- Publication number
- ATE69609T1 ATE69609T1 AT87907319T AT87907319T ATE69609T1 AT E69609 T1 ATE69609 T1 AT E69609T1 AT 87907319 T AT87907319 T AT 87907319T AT 87907319 T AT87907319 T AT 87907319T AT E69609 T1 ATE69609 T1 AT E69609T1
- Authority
- AT
- Austria
- Prior art keywords
- imidazolylphenylpyrrol
- cardiotonic
- ones
- novel
- compounds
- Prior art date
Links
- HTRFPPSJVNRYIQ-UHFFFAOYSA-N 4-(1h-imidazol-2-yl)-3-phenylpyrrol-2-one Chemical compound O=C1N=CC(C=2NC=CN=2)=C1C1=CC=CC=C1 HTRFPPSJVNRYIQ-UHFFFAOYSA-N 0.000 title abstract 2
- 230000003177 cardiotonic effect Effects 0.000 title 1
- 206010007559 Cardiac failure congestive Diseases 0.000 abstract 1
- 206010019280 Heart failures Diseases 0.000 abstract 1
- 239000000496 cardiotonic agent Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000002526 effect on cardiovascular system Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/925,956 US4737511A (en) | 1986-11-03 | 1986-11-03 | Cardiotonic imidazolylphenylpyrrol-2-ones |
| EP87907319A EP0329691B1 (de) | 1986-11-03 | 1987-10-31 | Cardiotonische imidazolylphenylpyrrol-2-one |
| PCT/EP1987/000650 WO1988003531A1 (fr) | 1986-11-03 | 1987-10-31 | Imidazolylphenylpyrrol-2-ones cardiotoniques |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE69609T1 true ATE69609T1 (de) | 1991-12-15 |
Family
ID=25452485
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT87907319T ATE69609T1 (de) | 1986-11-03 | 1987-10-31 | Cardiotonische imidazolylphenylpyrrol-2-one. |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US4737511A (de) |
| EP (1) | EP0329691B1 (de) |
| JP (1) | JPH02501064A (de) |
| AT (1) | ATE69609T1 (de) |
| DE (1) | DE3774715D1 (de) |
| WO (1) | WO1988003531A1 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5177089A (en) * | 1988-06-01 | 1993-01-05 | Eisai Co., Ltd. | Butenoic or propenoic acid derivative |
| FI892362L (fi) * | 1988-06-01 | 1989-12-02 | Eisai Co Ltd | Buten- eller propensyraderivat. |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GR73560B (de) * | 1979-02-24 | 1984-03-15 | Pfizer | |
| IL69407A (en) * | 1982-08-23 | 1987-10-20 | Warner Lambert Co | 2(1h)-pyridinones,their preparation and pharmaceutical compositions containing them |
| DE3433953A1 (de) * | 1984-09-15 | 1986-03-27 | A. Nattermann & Cie GmbH, 5000 Köln | Neue, eine imidazol-gruppe enthaltende 3,4-dihydro-2(1h)-pyridone und2(1h)-pyridone, verfahren zu ihrer herstellung und diese enthaltende arzneimittel |
-
1986
- 1986-11-03 US US06/925,956 patent/US4737511A/en not_active Expired - Lifetime
-
1987
- 1987-10-31 AT AT87907319T patent/ATE69609T1/de not_active IP Right Cessation
- 1987-10-31 EP EP87907319A patent/EP0329691B1/de not_active Expired - Lifetime
- 1987-10-31 JP JP62506765A patent/JPH02501064A/ja active Pending
- 1987-10-31 WO PCT/EP1987/000650 patent/WO1988003531A1/de not_active Ceased
- 1987-10-31 DE DE8787907319T patent/DE3774715D1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| WO1988003531A1 (fr) | 1988-05-19 |
| EP0329691B1 (de) | 1991-11-21 |
| JPH02501064A (ja) | 1990-04-12 |
| DE3774715D1 (de) | 1992-01-02 |
| EP0329691A1 (de) | 1989-08-30 |
| US4737511A (en) | 1988-04-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |