IT1271008B - Derivati del 2-ammino-1,2,3,4-tetraidro-naftalene attivi sul sistema cardiovascolare - Google Patents
Derivati del 2-ammino-1,2,3,4-tetraidro-naftalene attivi sul sistema cardiovascolareInfo
- Publication number
- IT1271008B IT1271008B ITMI941869A ITMI941869A IT1271008B IT 1271008 B IT1271008 B IT 1271008B IT MI941869 A ITMI941869 A IT MI941869A IT MI941869 A ITMI941869 A IT MI941869A IT 1271008 B IT1271008 B IT 1271008B
- Authority
- IT
- Italy
- Prior art keywords
- tetraidro
- naftalene
- amino
- cardiovascular system
- formula
- Prior art date
Links
- 210000000748 cardiovascular system Anatomy 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 206010058842 Cerebrovascular insufficiency Diseases 0.000 abstract 1
- 206010019280 Heart failures Diseases 0.000 abstract 1
- 208000005764 Peripheral Arterial Disease Diseases 0.000 abstract 1
- 208000030831 Peripheral arterial occlusive disease Diseases 0.000 abstract 1
- 208000001647 Renal Insufficiency Diseases 0.000 abstract 1
- 208000037849 arterial hypertension Diseases 0.000 abstract 1
- 208000026106 cerebrovascular disease Diseases 0.000 abstract 1
- 201000006370 kidney failure Diseases 0.000 abstract 1
- 208000031225 myocardial ischemia Diseases 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C215/64—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Vengono descritti composti di formula (FORMULA I) in cui R, R', R", R1, R2 ed m hanno i significati riportati nella descrizione; e loro sali farmaceuticamente accettabili.I composti di formula I sono utili nel trattamento dell'ipertensione arteriosa e dello scompenso cardiaco, dell'insufficienza renale, delle arteriopatie periferiche, delle insufficienze cerebrovascolari e della cardiopatia ischemica.
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI941869A IT1271008B (it) | 1994-09-13 | 1994-09-13 | Derivati del 2-ammino-1,2,3,4-tetraidro-naftalene attivi sul sistema cardiovascolare |
JP8509871A JPH10505096A (ja) | 1994-09-13 | 1995-09-05 | 心臓血管系に作用する2−アミノ−1,2,3,4−テトラヒドロナフタレン誘導体 |
DE69508947T DE69508947T2 (de) | 1994-09-13 | 1995-09-05 | Kardiovaskulär aktive 2-amino-1,2,3,4-tetrahydronaphthalene |
PCT/EP1995/003479 WO1996008463A1 (en) | 1994-09-13 | 1995-09-05 | Derivatives of 2-amino-1,2,3,4-tetrahydronaphthalene active on the cardiovascular system |
AT95932664T ATE178583T1 (de) | 1994-09-13 | 1995-09-05 | Kardiovaskulär aktive 2-amino-1,2,3,4- tetrahydronaphthalene |
EP95932664A EP0781268B1 (en) | 1994-09-13 | 1995-09-05 | Derivatives of 2-amino-1,2,3,4-tetrahydronaphthalene active on the cardiovascular system |
AU35633/95A AU3563395A (en) | 1994-09-13 | 1995-09-05 | Derivatives of 2-amino-1,2,3,4-tetrahydronaphthalene active on the cardiovascular system |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI941869A IT1271008B (it) | 1994-09-13 | 1994-09-13 | Derivati del 2-ammino-1,2,3,4-tetraidro-naftalene attivi sul sistema cardiovascolare |
Publications (3)
Publication Number | Publication Date |
---|---|
ITMI941869A0 ITMI941869A0 (it) | 1994-09-13 |
ITMI941869A1 ITMI941869A1 (it) | 1996-03-13 |
IT1271008B true IT1271008B (it) | 1997-05-26 |
Family
ID=11369549
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ITMI941869A IT1271008B (it) | 1994-09-13 | 1994-09-13 | Derivati del 2-ammino-1,2,3,4-tetraidro-naftalene attivi sul sistema cardiovascolare |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP0781268B1 (it) |
JP (1) | JPH10505096A (it) |
AT (1) | ATE178583T1 (it) |
AU (1) | AU3563395A (it) |
DE (1) | DE69508947T2 (it) |
IT (1) | IT1271008B (it) |
WO (1) | WO1996008463A1 (it) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2022040607A1 (en) * | 2020-08-20 | 2022-02-24 | Oregon Health & Science University | Small molecule albumin binders |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3263531D1 (en) * | 1981-08-05 | 1985-06-20 | Fisons Plc | Amine derivatives, processes for their production and pharmaceutical compositions containing them |
IT1254521B (it) * | 1992-03-17 | 1995-09-25 | Zambon Spa | Derivati della 2-ammino-tetralina attivi sul sistema cardiovascolare |
IT1271411B (it) * | 1993-09-14 | 1997-05-28 | Zambon Spa | Derivati del 2-ammino-1,2,3,4-tetraidro-naftalene attivi sul sistema cardiovascolare |
-
1994
- 1994-09-13 IT ITMI941869A patent/IT1271008B/it active IP Right Grant
-
1995
- 1995-09-05 AT AT95932664T patent/ATE178583T1/de active
- 1995-09-05 EP EP95932664A patent/EP0781268B1/en not_active Expired - Lifetime
- 1995-09-05 WO PCT/EP1995/003479 patent/WO1996008463A1/en active IP Right Grant
- 1995-09-05 DE DE69508947T patent/DE69508947T2/de not_active Expired - Fee Related
- 1995-09-05 AU AU35633/95A patent/AU3563395A/en not_active Abandoned
- 1995-09-05 JP JP8509871A patent/JPH10505096A/ja not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
ITMI941869A1 (it) | 1996-03-13 |
DE69508947D1 (de) | 1999-05-12 |
AU3563395A (en) | 1996-03-29 |
WO1996008463A1 (en) | 1996-03-21 |
EP0781268A1 (en) | 1997-07-02 |
EP0781268B1 (en) | 1999-04-07 |
ITMI941869A0 (it) | 1994-09-13 |
DE69508947T2 (de) | 1999-12-02 |
ATE178583T1 (de) | 1999-04-15 |
JPH10505096A (ja) | 1998-05-19 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
0001 | Granted | ||
TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19970825 |