DK0542923T3 - Liposomer, som giver thumusafhængig hjælp til svage vaccineantigener - Google Patents

Liposomer, som giver thumusafhængig hjælp til svage vaccineantigener

Info

Publication number
DK0542923T3
DK0542923T3 DK91918697.3T DK91918697T DK0542923T3 DK 0542923 T3 DK0542923 T3 DK 0542923T3 DK 91918697 T DK91918697 T DK 91918697T DK 0542923 T3 DK0542923 T3 DK 0542923T3
Authority
DK
Denmark
Prior art keywords
liposomes
thumus
vaccine antigens
antigen
dependent assistance
Prior art date
Application number
DK91918697.3T
Other languages
English (en)
Inventor
Nathalie Garcon
Howard R Six
Original Assignee
Res Dev Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Res Dev Foundation filed Critical Res Dev Foundation
Application granted granted Critical
Publication of DK0542923T3 publication Critical patent/DK0542923T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • A61K9/1271Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/39Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55555Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/829Liposomes, e.g. encapsulation

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK91918697.3T 1990-07-27 1991-07-24 Liposomer, som giver thumusafhængig hjælp til svage vaccineantigener DK0542923T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US55896090A 1990-07-27 1990-07-27

Publications (1)

Publication Number Publication Date
DK0542923T3 true DK0542923T3 (da) 1997-10-13

Family

ID=24231699

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91918697.3T DK0542923T3 (da) 1990-07-27 1991-07-24 Liposomer, som giver thumusafhængig hjælp til svage vaccineantigener

Country Status (22)

Country Link
US (1) US5464630A (da)
EP (1) EP0542923B1 (da)
JP (1) JP3518866B2 (da)
KR (1) KR100213851B1 (da)
CN (1) CN1032236C (da)
AT (1) ATE157537T1 (da)
AU (1) AU650299B2 (da)
CA (1) CA2088163C (da)
DE (1) DE69127545T2 (da)
DK (1) DK0542923T3 (da)
ES (1) ES2106088T3 (da)
FI (1) FI107515B (da)
GR (1) GR3025377T3 (da)
HK (1) HK1008304A1 (da)
IE (1) IE912535A1 (da)
IL (1) IL98935A (da)
NO (1) NO311167B1 (da)
NZ (1) NZ239072A (da)
PT (1) PT98470B (da)
RU (1) RU2107493C1 (da)
WO (1) WO1992002243A1 (da)
ZA (1) ZA915755B (da)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5879685A (en) * 1991-05-08 1999-03-09 Schweiz, Serum- & Impfinstitut Bern Immunostimulating and immunopotentiating reconstituted influenza virosomes and vaccines containing them
US6004534A (en) * 1993-07-23 1999-12-21 Massachusetts Institute Of Technology Targeted polymerized liposomes for improved drug delivery
AU3541495A (en) * 1994-09-01 1996-03-22 Wisconsin Alumni Research Foundation Therapeutic remodeling in aids
US6060082A (en) 1997-04-18 2000-05-09 Massachusetts Institute Of Technology Polymerized liposomes targeted to M cells and useful for oral or mucosal drug delivery
AUPO732997A0 (en) 1997-06-12 1997-07-03 Csl Limited Ganglioside immunostimulating complexes and uses thereof
US5993852A (en) * 1997-08-29 1999-11-30 Pharmaderm Laboratories Ltd. Biphasic lipid vesicle composition for transdermal administration of an immunogen
US6027731A (en) * 1998-11-17 2000-02-22 Wisconsin Alumni Research Foundation Pertussis toxin induced lymphocytosis
WO2003009868A1 (en) * 2001-07-26 2003-02-06 Otago Innovation Limited Antigenic compositions
ATE537813T1 (de) * 2005-09-30 2012-01-15 Lipoxen Technologies Ltd Liposomale impfstoff-zusammensetzung aus einem polysaccharid-antigen und einem protein-adjuvans
RU2480479C1 (ru) * 2011-11-01 2013-04-27 Елена Викторовна Свирщевская Гетерологичный пептидный мини-антиген в составе полимерной частицы для создания противоаллергенной вакцины
JP6523685B2 (ja) 2012-01-03 2019-06-05 アメリカ合衆国 Muc1腫瘍抗原のネイティブ及びアゴニストctlエピトープ
JP6788500B2 (ja) 2013-10-23 2020-11-25 アメリカ合衆国 Muc1−c癌タンパク質のhla−a24アゴニストエピトープ及び組成物及び使用方法
CN116196403A (zh) 2015-08-03 2023-06-02 美国卫生和人力服务部 Brachyury缺失突变体、编码该缺失突变体的非酵母载体及其用途
CA3042703A1 (en) 2016-11-07 2018-05-11 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Development of agonist epitopes of the human papillomavirus
CA3119736A1 (en) 2018-11-14 2020-05-22 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Tp5, a peptide inhibitor of aberrant and hyperactive cdk5/p25 as treatment for cancer
AU2021210915A1 (en) 2020-01-21 2022-09-15 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Human immunogenic epitopes of HEMO and HHLA2 human endogenous retroviruses (HERVs)
WO2021150713A2 (en) 2020-01-21 2021-07-29 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Human immunogenic epitopes of h, k, and e human endogenous retroviruses (hervs)

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2009343C3 (de) * 1970-02-27 1980-10-23 Max-Planck-Gesellschaft Zur Foerderung Der Wissenschaften E.V., 3400 Goettingen Verwendung von Lysolecithinen als immunologische Adjuvantien
GB1502774A (en) * 1974-06-25 1978-03-01 Nat Res Dev Immunological preparations
US4196191A (en) * 1975-09-29 1980-04-01 Burroughs Wellcome Co. Biological preparations
US4235871A (en) * 1978-02-24 1980-11-25 Papahadjopoulos Demetrios P Method of encapsulating biologically active materials in lipid vesicles
GB2026340B (en) * 1978-07-03 1982-12-22 Ash P Stabilising microvesicles
US4199565A (en) * 1979-03-26 1980-04-22 Merck & Co., Inc. Liposome particle containing viral or bacterial antigenic subunit
HU184141B (en) * 1979-12-27 1984-07-30 Human Oltoanyagtermelo Adjuvant particles compositions containing said particles and biologically active substances adsorbed thereon and a process for the preparation thereof
US4902506A (en) * 1983-07-05 1990-02-20 The University Of Rochester Immunogenic conjugates
US4673574A (en) * 1981-08-31 1987-06-16 Anderson Porter W Immunogenic conjugates
US4761283A (en) * 1983-07-05 1988-08-02 The University Of Rochester Immunogenic conjugates
US4565696A (en) * 1983-08-03 1986-01-21 The Regents Of The University Of California Production of immunogens by antigen conjugation to liposomes
US4708933A (en) * 1984-06-12 1987-11-24 Leaf Huang Immunoliposome assay-methods and products
CA1267087A (en) * 1985-02-14 1990-03-27 Nicolaas Visser Synthetic immunogen
US4797285A (en) * 1985-12-06 1989-01-10 Yissum Research And Development Company Of The Hebrew University Of Jerusalem Lipsome/anthraquinone drug composition and method
US4882145A (en) * 1986-12-09 1989-11-21 Scripps Clinic And Research Foundation T cell epitopes of the hepatitis B virus nucleocapsid protein
EP0306912A3 (en) * 1987-09-08 1989-07-05 Albany Medical College Immunogenic composites capable of selectively inducing antibody production and pharmaceutical compositions employing the same.

Also Published As

Publication number Publication date
ZA915755B (en) 1993-02-24
WO1992002243A1 (en) 1992-02-20
NO311167B1 (no) 2001-10-22
FI930319A0 (fi) 1993-01-26
GR3025377T3 (en) 1998-02-27
NZ239072A (en) 1997-06-24
HK1008304A1 (en) 1999-05-07
CA2088163C (en) 2003-06-17
JPH06502630A (ja) 1994-03-24
IE912535A1 (en) 1992-01-29
AU8759791A (en) 1992-03-02
RU2107493C1 (ru) 1998-03-27
FI930319A (fi) 1993-01-26
ES2106088T3 (es) 1997-11-01
PT98470A (pt) 1992-06-30
EP0542923A1 (en) 1993-05-26
CN1032236C (zh) 1996-07-10
EP0542923A4 (da) 1994-04-13
CN1059279A (zh) 1992-03-11
AU650299B2 (en) 1994-06-16
IL98935A0 (en) 1992-07-15
JP3518866B2 (ja) 2004-04-12
US5464630A (en) 1995-11-07
DE69127545T2 (de) 1998-01-08
CA2088163A1 (en) 1992-01-28
DE69127545D1 (de) 1997-10-09
NO930202D0 (no) 1993-01-21
ATE157537T1 (de) 1997-09-15
EP0542923B1 (en) 1997-09-03
IL98935A (en) 1994-01-24
PT98470B (pt) 1998-02-27
FI107515B (fi) 2001-08-31
NO930202L (no) 1993-01-21
KR100213851B1 (ko) 1999-08-02

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