DK0540573T3 - Assay for frit- og kompleksbundet prostataspecifikt antigen (PSA) - Google Patents

Assay for frit- og kompleksbundet prostataspecifikt antigen (PSA)

Info

Publication number
DK0540573T3
DK0540573T3 DK91913019.5T DK91913019T DK0540573T3 DK 0540573 T3 DK0540573 T3 DK 0540573T3 DK 91913019 T DK91913019 T DK 91913019T DK 0540573 T3 DK0540573 T3 DK 0540573T3
Authority
DK
Denmark
Prior art keywords
psa
free
assay
specific antigen
prostate specific
Prior art date
Application number
DK91913019.5T
Other languages
English (en)
Other versions
DK0540573T4 (da
Inventor
Hans Lilja
Ulf-Hakan Stenman
Original Assignee
Hans Lilja
Stenman Ulf Hakan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=20380033&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0540573(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hans Lilja, Stenman Ulf Hakan filed Critical Hans Lilja
Application granted granted Critical
Publication of DK0540573T3 publication Critical patent/DK0540573T3/da
Publication of DK0540573T4 publication Critical patent/DK0540573T4/da

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57438—Specifically defined cancers of liver, pancreas or kidney

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK91913019T 1990-07-23 1991-07-22 Assay for frit- og kompleksbundet prostataspecifikt antigen (PSA) DK0540573T4 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9002480A SE9002480D0 (sv) 1990-07-23 1990-07-23 Assay of free and complexed prostate-specific antigen
PCT/FI1991/000223 WO1992001936A1 (en) 1990-07-23 1991-07-22 Assay of free and complexed prostate-specific antigen (psa)

Publications (2)

Publication Number Publication Date
DK0540573T3 true DK0540573T3 (da) 1996-04-09
DK0540573T4 DK0540573T4 (da) 2004-04-05

Family

ID=20380033

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91913019T DK0540573T4 (da) 1990-07-23 1991-07-22 Assay for frit- og kompleksbundet prostataspecifikt antigen (PSA)

Country Status (10)

Country Link
US (4) US5501983A (da)
EP (1) EP0540573B2 (da)
JP (1) JP2669566B2 (da)
AT (1) ATE134448T1 (da)
DE (2) DE540573T1 (da)
DK (1) DK0540573T4 (da)
ES (1) ES2070107T5 (da)
GR (1) GR3019888T3 (da)
SE (1) SE9002480D0 (da)
WO (1) WO1992001936A1 (da)

Families Citing this family (96)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5965379A (en) * 1991-07-19 1999-10-12 Cytimmune Sciences Inc. Method for measuring endogenous cytokines
GB9309966D0 (en) * 1993-05-14 1993-06-30 Nordion Int Inc Detection of prostrate-specific antigen in breast tumors
GB9314623D0 (en) * 1993-07-14 1993-08-25 Nordion Int Inc Localization and therapy with agents directed against prostate specific antigen in breast cancer
EP0635575A1 (en) 1993-07-22 1995-01-25 Wallac Oy Monoclonal antibodies against epitopes found in free but not in alpha-1-antichmotrypsin complexed prostate specific antigen
EP0652014A1 (en) * 1993-11-10 1995-05-10 National Institute Of Immunology Treatment of prostatic hypertrophy
US5599677A (en) * 1993-12-29 1997-02-04 Abbott Laboratories Immunoassays for prostate specific antigen
US6143864A (en) * 1994-06-28 2000-11-07 Merck & Co., Inc. Peptides
US5599686A (en) * 1994-06-28 1997-02-04 Merck & Co., Inc. Peptides
US5866679A (en) * 1994-06-28 1999-02-02 Merck & Co., Inc. Peptides
GB9415489D0 (en) * 1994-08-01 1994-09-21 Nordion Int Inc Detection of prostate-specific antigen in amniotic fluid
EP0725139A3 (en) * 1995-02-03 1997-11-26 Bayer Corporation Recombinant prostate-specific antigen and its use as an immunoassay calibrator
US5698402A (en) * 1995-02-23 1997-12-16 Dianon Systems, Inc. Methods for diagnosing benign prostatic hyperplasia
US5614372A (en) * 1995-02-24 1997-03-25 Lilja; Hans Early detection of prostate cancer (CAP) by employing prostate specific antigen (PSA) and human glandular kallikrein (hGK-1)
US5654161A (en) * 1995-05-12 1997-08-05 Chiron Diagnostics Corporation Method for diagnosing prostate cancer
US5807978A (en) * 1995-06-07 1998-09-15 Kokolus; William J. Immunogenic peptides of prostate specific antigen
US5800347A (en) * 1995-11-03 1998-09-01 The General Hospital Corporation ROC method for early detection of disease
WO1997009925A2 (en) * 1995-09-12 1997-03-20 The General Hospital Corporation Method for early detection of ovarian cancer
US5710007A (en) * 1995-09-29 1998-01-20 Luderer; Albert A. Methods for diagnosing prostatic adenocarcinoma
JP2000506494A (ja) * 1995-10-18 2000-05-30 メルク エンド カンパニー インコーポレーテッド 良性前立腺過形成の治療に有用な複合体
EP0789032A2 (en) * 1996-02-01 1997-08-13 Bayer Corporation Method for preparing a monoclonal antibody that provides an equimolar response to free and complexed analyte in a monoclonal/polyclonal sandwich immunoassay
US6143509A (en) * 1996-02-06 2000-11-07 Abbott Laboratories Prostate specific antigen peptides and uses thereof
AU775537B2 (en) * 1996-04-26 2004-08-05 Children's Medical Center Corporation Non-invasive enzyme screen for tissue remodelling-associated conditions
AU2681997A (en) * 1996-04-26 1997-11-19 Children's Medical Center Corporation Non-invasive enzyme screen for tissue remodelling-associated conditions
US6811995B1 (en) 1996-04-26 2004-11-02 Children's Medical Center Corporation Non-invasive enzyme screen for cancer
WO1998010292A1 (en) * 1996-09-06 1998-03-12 Centocor, Inc. Monoclonal antibodies specific for prostate specific antigen and methods of detecting prostate specific antigen
DE19641560A1 (de) * 1996-10-09 1998-04-16 Boehringer Mannheim Gmbh Monoklonale Antikörper gegen einen Komplex aus humanem ACT und einer Serinprotease
US6107103A (en) * 1996-10-15 2000-08-22 Procyon Bropharma Inc. Assay for PSP94 protein
US6177404B1 (en) 1996-10-15 2001-01-23 Merck & Co., Inc. Conjugates useful in the treatment of benign prostatic hyperplasia
IL121659A (en) * 1996-10-25 2000-07-16 Bayer Ag Method for determining CPSA in a blood sample
US5840501A (en) * 1996-10-25 1998-11-24 Bayer Corporation Determination of cPSA
US5856182A (en) * 1996-11-18 1999-01-05 Beckman Coulter, Inc. Monoclonal antibodies specific for the PSA-ACT complex
US6548260B1 (en) * 1997-01-21 2003-04-15 Bayer Corporation Detection of PSA-α2-macroglobulin complex in a biological fluid
US6309816B1 (en) * 1997-04-16 2001-10-30 Horus Therapeutics, Inc. Methods for diagnosing cancer by measuring creatine kinase
DE19717436C2 (de) * 1997-04-25 2001-02-15 Biomac Gmbh Verfahren zur exakten Bestimmung von Prostata-spezifischem Antigen in Körperflüssigkeiten
US7288636B2 (en) * 1997-04-30 2007-10-30 Hybritech Incorporated Forms of prostate specific antigens and methods for their detection
CA2290582C (en) * 1997-05-14 2005-08-02 Kenneth F. Buechler Rapid evaluation of the ratio of biological molecules
US5994085A (en) * 1997-08-26 1999-11-30 Cantor; Thomas L. Methods and devices for detecting non-complexed prostate specific antigen
US6649420B1 (en) 1997-08-26 2003-11-18 Thomas L. Cantor Methods and devices for detecting no-complexed prostate specific I antigen
US6300088B1 (en) 1997-11-24 2001-10-09 Duke University Method of detecting prostate specific antigen
DE19814915A1 (de) 1998-04-03 1999-10-07 Roche Diagnostics Gmbh Immunologisches Verfahren zur Bestimmung von PSA
FI981185A (fi) * 1998-05-28 1999-11-29 Stenman Ulf Haakan Uusi diagnostinen menetelmä
FI981186A (fi) * 1998-05-28 1999-11-29 Stenman Ulf Haakan Uusi immunomääritys ja sen käyttö diagnostiikassa
AU5128799A (en) * 1998-07-24 2000-02-14 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Pb 39, a gene dysregulated in prostate cancer, and uses thereof
US7226731B1 (en) 1998-07-24 2007-06-05 The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services PB 39, a gene dysregulated in prostate cancer, and uses thereof
EP1104462B1 (en) * 1998-08-10 2007-01-03 Agensys, Inc. Bpc-1: a secreted brain specific protein expressed and secreted by prostate and bladder cancer cells
JP4723725B2 (ja) 1999-04-20 2011-07-13 ターゲット ディスカバリー， インコーポレイテッド 代謝経路を分析するための方法
US6423503B1 (en) * 1999-04-30 2002-07-23 Hybritech Incorporated Forms of free prostate-specific antigen (PSA) and their association with prostate tissues from prostate peripheral zone and transition zone
US6893818B1 (en) 1999-10-28 2005-05-17 Agensys, Inc. Gene upregulated in cancers of the prostate
FR2807438B1 (fr) * 2000-04-10 2004-09-17 Bio Merieux Nouveaux anticorps reconnaissant specifiquement le psa libre inactif, et leurs applications
GB0012718D0 (en) * 2000-05-24 2000-07-19 Angeletti P Ist Richerche Bio Conjugates of aminodrugs
FR2810114B1 (fr) * 2000-06-13 2002-08-23 Bio Merieux Methode, procede, test immunologique et kit de diagnostic d'un adenocarcinome de la prostate ou d'une hypertrophie benigne de la prostate
DE60138465D1 (de) 2000-07-12 2009-06-04 Agensys Inc Neues tumor antigen das für diagnose und therapie von blasen-, eierstock-, lungen- und nierenkrebs verwendet werden kann
US6379550B1 (en) 2000-07-24 2002-04-30 Health Research, Inc. Method for detecting PSA and its molecular forms using thiophilic gel
ATE282205T1 (de) 2000-07-24 2004-11-15 Health Research Inc Verfahren zur detektion von prostata-spezifischem membran-antigen in serum
US6984494B2 (en) * 2000-08-15 2006-01-10 Genentech, Inc. Analytical method
ES2281437T3 (es) 2000-08-22 2007-10-01 Agensys, Inc. Acido nucleico y proteina correspondiente denominada 158p1d7 util para el tratamiento y la deteccion del cancer de vejiga y otros canceres.
CA2420990C (en) 2000-08-28 2010-08-17 Agensys, Inc. Nucleic acid and corresponding protein entitled 85p1b3 useful in treatment and detection of cancer
US6764825B1 (en) * 2000-10-13 2004-07-20 Tang J. Wang Methods and device for detecting prostate specific antigen (PSA)
US6924358B2 (en) 2001-03-05 2005-08-02 Agensys, Inc. 121P1F1: a tissue specific protein highly expressed in various cancers
US7271240B2 (en) 2001-03-14 2007-09-18 Agensys, Inc. 125P5C8: a tissue specific protein highly expressed in various cancers
US20030191073A1 (en) 2001-11-07 2003-10-09 Challita-Eid Pia M. Nucleic acid and corresponding protein entitled 161P2F10B useful in treatment and detection of cancer
WO2002083921A2 (en) 2001-04-10 2002-10-24 Agensys, Inc. Nuleic acids and corresponding proteins useful in the detection and treatment of various cancers
ES2532757T3 (es) 2001-09-06 2015-03-31 Agensys, Inc. Ácido nucleico y proteína correspondiente denominados STEAP-1 útiles en el tratamiento y la detección de cáncer
US7842498B2 (en) 2001-11-08 2010-11-30 Bio-Rad Laboratories, Inc. Hydrophobic surface chip
US7534580B2 (en) * 2002-05-01 2009-05-19 Ambrilia Biopharma Inc. PSP94 diagnostic reagents and assays
WO2004016733A2 (en) 2002-08-16 2004-02-26 Agensys, Inc. Nucleic acid and corresponding protein entitled 251p5g2 useful in treatment and detection of cancer
US20040176577A1 (en) * 2002-09-10 2004-09-09 Eva Rojer Immunoassays for specific determination of SCCA isoforms
DK1563100T3 (da) * 2002-11-01 2013-08-05 Iris Int Inc Fortrængningssandwich-immuno-PCR
JP2006508163A (ja) 2002-11-27 2006-03-09 アジェンシス， インコーポレイテッド 癌の処置および検出において有用な２４ｐ４ｃ１２と称される、核酸および対応タンパク質
JP2007524361A (ja) 2003-02-10 2007-08-30 アジェンシス， インコーポレイテッド 膀胱癌及びその他の癌の治療及び検出に有用な名称１５８ｐ１ｄ７の核酸及び対応タンパク質
US20040229300A1 (en) * 2003-04-22 2004-11-18 Frederickson Christopher J. Zinc-based screening test and kit for early diagnosis of prostate cancer
ATE541052T1 (de) 2003-05-30 2012-01-15 Agensys Inc Varianten des prostata-stammzellen-antigens (psca) und teilsequenzen davon
CA2567449C (en) 2004-05-28 2014-03-11 Agensys, Inc. Antibodies and related molecules that bind to psca proteins
DE102004027429B4 (de) 2004-06-04 2018-09-13 Siemens Healthcare Diagnostics Gmbh Verfahren zur Anwendung von auf Markerwerten basierenden Dichtekarten bei der Diagnose von Patienten mit Krankheiten insbesondere von Tumoren
CN103146808A (zh) * 2004-11-03 2013-06-12 意力速分子诊断股份有限公司 均相分析物检测
ATE530666T1 (de) * 2004-11-03 2011-11-15 Iris Molecular Diagnostics Inc Mikrobläschen zur affinitätstrennung
US8663600B2 (en) * 2005-02-17 2014-03-04 Diaprost Ab Diagnosis of prostate cancer
US20080125582A1 (en) * 2006-10-13 2008-05-29 Bio-Rad Laboratories, Inc. Methods and compositions for stabilizing prostate specific antigen
US20090062624A1 (en) * 2007-04-26 2009-03-05 Thomas Neville Methods and systems of delivering a probability of a medical condition
CN101754812B (zh) 2007-05-04 2013-06-26 克拉洛诊断仪器公司 流体连接器和微流体系统
WO2009029550A2 (en) * 2007-08-24 2009-03-05 Singulex, Inc. Highly sensitive system and methods for analysis of prostate specific antigen (psa)
US8362325B2 (en) 2007-10-03 2013-01-29 Ceres, Inc. Nucleotide sequences and corresponding polypeptides conferring modulated plant characteristics
EP2623985A1 (en) * 2008-02-21 2013-08-07 Iris International, Inc. Method for early determination of recurrence after therapy for prostate cancer
US8538778B2 (en) * 2008-05-15 2013-09-17 Soar Biodynamics, Ltd. Methods and systems for integrated health systems
WO2010075446A1 (en) * 2008-12-23 2010-07-01 Soar Biodynamics, Ltd. Methods and systems for prostate health monitoring
US20100173791A1 (en) 2009-01-05 2010-07-08 Bio-Rad Laboratories, Inc. Process design using mass spectrometry
ES2695039T3 (es) 2009-02-02 2018-12-28 Opko Diagnostics, Llc Estructuras para controlar la interacción de luz con dispositivos microfluídicos
EP2239675A1 (en) 2009-04-07 2010-10-13 BIOCRATES Life Sciences AG Method for in vitro diagnosing a complex disease
CN102346536A (zh) * 2010-07-29 2012-02-08 元太科技工业股份有限公司 省电触控电子书
KR101835918B1 (ko) 2011-03-28 2018-03-07 세키스이 메디칼 가부시키가이샤 Psa의 측정 방법 및 그의 시약
CN106872702A (zh) 2011-10-25 2017-06-20 斯隆－凯特林纪念癌症中心 用于前列腺癌的诊断、预测和治疗的游离psa抗体
BR112014013853A2 (pt) 2011-12-09 2020-01-14 Ceres Inc uso de um ácido nucleico isolado, método de obtenção de uma célula vegetal transgênica, método de obtenção de uma planta transgênica, método de produção de uma planta, método de produção de biomassa, método de processamento de biomassa, método de alteração da composição de biomassa, método de modulação de composição de biomassa, método de produção de um produto de forragem
EP3312749B1 (en) 2012-03-05 2024-05-01 OY Arctic Partners AB Methods and apparatuses for predicting risk of prostate cancer and prostate gland volume
BR112016022407A2 (pt) 2014-03-28 2017-12-12 Opko Diagnostics Llc composições e métodos relacionados ao diagnóstico do câncer de próstata
UA124522C2 (uk) 2015-03-27 2021-10-05 Опко Дайегностікс, Елелсі Спосіб кількісної оцінки рівнів простатичного антигену
CN108802392A (zh) * 2018-08-29 2018-11-13 上海市东方医院 一种用于诊断前列腺癌的层析试纸条及其制备方法和应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4446122A (en) * 1979-12-28 1984-05-01 Research Corporation Purified human prostate antigen
JPS57500169A (da) * 1979-12-28 1982-01-28
US4690890A (en) * 1984-04-04 1987-09-01 Cetus Corporation Process for simultaneously detecting multiple antigens using dual sandwich immunometric assay
IE62580B1 (en) * 1985-03-29 1995-02-08 Hybritech Inc Processes for the stabilization of prostate specific antigen in natural matrices
JPH0690203B2 (ja) * 1985-08-23 1994-11-14 中外製薬株式会社 前立腺特異抗原とα▲下１▼−アンチトリプシン複合体の定量方法
US5599677A (en) * 1993-12-29 1997-02-04 Abbott Laboratories Immunoassays for prostate specific antigen
US5599686A (en) * 1994-06-28 1997-02-04 Merck & Co., Inc. Peptides

Also Published As

Publication number Publication date
EP0540573A1 (en) 1993-05-12
ES2070107T1 (es) 1995-06-01
GR3019888T3 (en) 1996-08-31
US5501983A (en) 1996-03-26
DK0540573T4 (da) 2004-04-05
JP2669566B2 (ja) 1997-10-29
US20020123616A1 (en) 2002-09-05
ATE134448T1 (de) 1996-03-15
EP0540573B1 (en) 1996-02-21
ES2070107T5 (es) 2004-05-16
DE69117292T3 (de) 2004-06-03
DE540573T1 (de) 1995-09-28
US5939533A (en) 1999-08-17
SE9002480D0 (sv) 1990-07-23
US5912158A (en) 1999-06-15
JPH06502719A (ja) 1994-03-24
DE69117292T2 (de) 1996-07-18
WO1992001936A1 (en) 1992-02-06
DE69117292D1 (de) 1996-03-28
EP0540573B2 (en) 2003-11-19
ES2070107T3 (es) 1996-04-16

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