DK0540526T3 - Quinuclidinderivater - Google Patents

Quinuclidinderivater

Info

Publication number
DK0540526T3
DK0540526T3 DK91909987.9T DK91909987T DK0540526T3 DK 0540526 T3 DK0540526 T3 DK 0540526T3 DK 91909987 T DK91909987 T DK 91909987T DK 0540526 T3 DK0540526 T3 DK 0540526T3
Authority
DK
Denmark
Prior art keywords
quinuclidine derivatives
quinuclidine
derivatives
migraine
antagonists
Prior art date
Application number
DK91909987.9T
Other languages
Danish (da)
English (en)
Inventor
John A Lowe Iii
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of DK0540526T3 publication Critical patent/DK0540526T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Soft Magnetic Materials (AREA)
  • Paper (AREA)
  • Control Of Electric Motors In General (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK91909987.9T 1990-07-23 1991-05-14 Quinuclidinderivater DK0540526T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US55744290A 1990-07-23 1990-07-23

Publications (1)

Publication Number Publication Date
DK0540526T3 true DK0540526T3 (da) 1995-04-18

Family

ID=24225412

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91909987.9T DK0540526T3 (da) 1990-07-23 1991-05-14 Quinuclidinderivater

Country Status (25)

Country Link
US (5) US5422354A (pt)
EP (1) EP0540526B1 (pt)
JP (1) JP2514137B2 (pt)
CN (1) CN1058405A (pt)
AT (1) ATE116317T1 (pt)
AU (1) AU660416B2 (pt)
BR (1) BR9106665A (pt)
CA (1) CA2086434C (pt)
DE (1) DE69106365T2 (pt)
DK (1) DK0540526T3 (pt)
ES (1) ES2065691T3 (pt)
FI (1) FI114473B (pt)
GR (1) GR3015144T3 (pt)
HU (1) HUT62584A (pt)
IE (1) IE65000B1 (pt)
IL (1) IL98860A (pt)
MX (1) MX9100308A (pt)
MY (1) MY107157A (pt)
NO (1) NO302172B1 (pt)
NZ (1) NZ239063A (pt)
PL (1) PL167568B1 (pt)
PT (1) PT98393B (pt)
WO (1) WO1992001688A1 (pt)
YU (1) YU128091A (pt)
ZA (1) ZA915727B (pt)

Families Citing this family (73)

* Cited by examiner, † Cited by third party
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RU2114848C1 (ru) * 1991-06-20 1998-07-10 Пфайзер Инк. Фторалкоксибензиламинные производные азотсодержащих гетероциклов, фармацевтическая композиция, способ ингибирования действия вещества р у млекопитающих
TW202432B (pt) * 1991-06-21 1993-03-21 Pfizer
DK0607164T3 (da) * 1991-09-26 2002-06-17 Pfizer Kondenserede tricykliske nitrogenholdige heterocykliske forbindelser som substans P-receptorantagonister
AU2681392A (en) * 1991-11-12 1993-06-15 Pfizer Inc. Acyclic ethylenediamine derivatives as substance p receptor antagonists
CA2134964C (en) * 1992-05-18 1997-12-30 Manoj C. Desai Bridged aza-bicyclic derivatives as substance p antagonists
US5688804A (en) * 1992-08-04 1997-11-18 Pfizer Inc. 3-Benzylamino-2-phenyl-piperidine derivatives as substance P receptor antagonists
EP0655996B1 (en) * 1992-08-19 2001-11-07 Pfizer Inc. Substituted benzylamino nitrogen containing non-aromatic heterocycles
ATE194340T1 (de) * 1992-12-10 2000-07-15 Pfizer Aminomethylen substituierte heterocyclische verbindungen und ihre verwendung alssubstanz p antagonisten
US5830854A (en) * 1992-12-14 1998-11-03 Merck Sharp & Dohme, Limited Method of treating cystic fibrosis using a tachykinin receptor antagonist
US5340826A (en) * 1993-02-04 1994-08-23 Pfizer Inc. Pharmaceutical agents for treatment of urinary incontinence
US5393762A (en) * 1993-06-04 1995-02-28 Pfizer Inc. Pharmaceutical agents for treatment of emesis
EP0655246A1 (en) * 1993-11-30 1995-05-31 Pfizer Inc. Substance P antagonists for the treatment of disorders caused by helicobacter pylori or other spiral urease-positive gram-negative bacteria
FR2725900B1 (fr) * 1994-10-21 1997-07-18 Sanofi Sa Utilisation d'antagonistes des recepteurs nk1 pour la preparation de medicaments a action cardioregulatrice
IL116249A (en) * 1994-12-12 2003-07-06 Pfizer Nk-1 receptor antagonists for the treatment of neuronal damage and stroke
GB9502582D0 (en) * 1995-02-10 1995-03-29 Smithkline Beecham Plc Novel process
GB9510459D0 (en) 1995-05-24 1995-07-19 Zeneca Ltd Bicyclic amines
ES2218676T3 (es) * 1996-05-13 2004-11-16 Syngenta Limited Aminas biciclicas como insecticidas.
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GB9623944D0 (en) * 1996-11-15 1997-01-08 Zeneca Ltd Bicyclic amine derivatives
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EP0944627B1 (en) 1996-11-26 2004-02-18 Syngenta Limited 8-azabicyclo 3.2.1]octane-, 8-azabicyclo 3.2.1]oct-6-ene-, 9-azabicyclo 3.3.1]nonane-, 9-aza-3-oxabicyclo 3.3.1]nonane- and 9-aza-3-thiabicyclo 3.3.1]nonane derivatives, their preparation and their use as insecticides
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WO2001023385A2 (en) * 1999-09-27 2001-04-05 Georgetown University Novel tropane analogs
JP2001172178A (ja) * 1999-10-25 2001-06-26 Pfizer Prod Inc 偏頭痛治療用のｎｋ−１レセプターアンタゴニスト及びエレトリプタン
ATE387429T1 (de) 1999-11-03 2008-03-15 Amr Technology Inc Arly- und heteroaryl-substituierte tetrahydroisoquinoline und ihre verwendung als hemmer der wiederaufnahme von norepinephrin, dopamin und serotonin
US7163949B1 (en) 1999-11-03 2007-01-16 Amr Technology, Inc. 4-phenyl substituted tetrahydroisoquinolines and use thereof
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US20020049211A1 (en) * 2000-09-06 2002-04-25 Sobolov-Jaynes Susan Beth Combination treatment for depression and anxiety
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US8691825B2 (en) 2009-04-01 2014-04-08 Merck Sharp & Dohme Corp. Inhibitors of AKT activity
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Family Cites Families (8)

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US3560510A (en) * 1969-03-05 1971-02-02 Aldrich Chem Co Inc 2-benzhydrylquinuclidines
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EP0540526B1 (en) * 1990-07-23 1994-12-28 Pfizer Inc. Quinuclidine derivatives

Also Published As

Publication number Publication date
EP0540526B1 (en) 1994-12-28
NZ239063A (en) 1995-09-26
FI114473B (fi) 2004-10-29
BR9106665A (pt) 1993-06-08
JP2514137B2 (ja) 1996-07-10
IL98860A0 (en) 1992-07-15
MY107157A (en) 1995-09-30
CA2086434A1 (en) 1992-01-24
HU9300188D0 (en) 1993-04-28
EP0540526A1 (en) 1993-05-12
IE912560A1 (en) 1992-01-29
NO930222L (no) 1993-01-22
PL167568B1 (pl) 1995-09-30
PT98393B (pt) 1999-01-29
US5698568A (en) 1997-12-16
YU128091A (sh) 1994-01-20
IL98860A (en) 1995-11-27
NO930222D0 (no) 1993-01-22
IE65000B1 (en) 1995-10-04
AU660416B2 (en) 1995-06-29
US5821248A (en) 1998-10-13
JPH05507687A (ja) 1993-11-04
FI930262A (fi) 1993-01-22
CN1058405A (zh) 1992-02-05
DE69106365D1 (de) 1995-02-09
HUT62584A (en) 1993-05-28
AU7894891A (en) 1992-02-18
ATE116317T1 (de) 1995-01-15
MX9100308A (es) 1992-02-28
ZA915727B (en) 1993-02-24
US5422354A (en) 1995-06-06
WO1992001688A1 (en) 1992-02-06
US5854256A (en) 1998-12-29
US5641786A (en) 1997-06-24
FI930262A0 (fi) 1993-01-22
PT98393A (pt) 1992-05-29
GR3015144T3 (en) 1995-05-31
CA2086434C (en) 1998-09-22
ES2065691T3 (es) 1995-02-16
DE69106365T2 (de) 1995-05-04
NO302172B1 (no) 1998-02-02

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