DK0529636T3 - Hidtil ukendte isatinoximderivater, deres fremstilling og anvendelse - Google Patents
Hidtil ukendte isatinoximderivater, deres fremstilling og anvendelseInfo
- Publication number
- DK0529636T3 DK0529636T3 DK92114654T DK92114654T DK0529636T3 DK 0529636 T3 DK0529636 T3 DK 0529636T3 DK 92114654 T DK92114654 T DK 92114654T DK 92114654 T DK92114654 T DK 92114654T DK 0529636 T3 DK0529636 T3 DK 0529636T3
- Authority
- DK
- Denmark
- Prior art keywords
- cyclic
- branched
- alkyl
- hydrogen
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/45—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by at least one doubly—bound oxygen atom, not being part of a —CHO group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Hydrogenated Pyridines (AREA)
- Medicinal Preparation (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US75116591A | 1991-08-28 | 1991-08-28 | |
| US83185192A | 1992-02-05 | 1992-02-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0529636T3 true DK0529636T3 (da) | 1999-12-13 |
Family
ID=27115380
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK92114654T DK0529636T3 (da) | 1991-08-28 | 1992-08-27 | Hidtil ukendte isatinoximderivater, deres fremstilling og anvendelse |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP0529636B1 (de) |
| JP (1) | JP3170584B2 (de) |
| KR (1) | KR100277481B1 (de) |
| AT (1) | ATE181552T1 (de) |
| AU (1) | AU655672B2 (de) |
| CA (1) | CA2076948C (de) |
| CZ (1) | CZ282759B6 (de) |
| DE (1) | DE69229461T2 (de) |
| DK (1) | DK0529636T3 (de) |
| FI (1) | FI107156B (de) |
| GE (1) | GEP20002329B (de) |
| HU (2) | HUT70753A (de) |
| MX (1) | MX9204914A (de) |
| NO (1) | NO301117B1 (de) |
| PL (1) | PL170920B1 (de) |
| RU (1) | RU2114827C1 (de) |
| SK (1) | SK280578B6 (de) |
| WO (1) | WO1993005043A1 (de) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE157977T1 (de) | 1992-10-13 | 1997-09-15 | Warner Lambert Co | Chinoxalinderivate als eaa antagonisten |
| US5843945A (en) * | 1993-05-13 | 1998-12-01 | Neurosearch A/S | AMPA antagonists and a method of treatment |
| NZ267081A (en) * | 1993-05-13 | 1997-11-24 | Neurosearch As | Hetero-fused indole and quinoxaline compounds and medicaments thereof |
| DK81593D0 (da) * | 1993-07-07 | 1993-07-07 | Neurosearch As | Nye isatinoximderivater, deres fremstilling og anvendelse |
| EE03355B1 (et) * | 1994-09-14 | 2001-02-15 | Neurosearch A/S | Indool-2,3-dioon-3-oksiimi derivaadid, nende valmistamine ja kasutamine |
| DE69514533T2 (de) * | 1994-09-14 | 2000-07-06 | Neurosearch A/S, Ballerup | Kondensierte indole und chinoxalinderivate, ihre herstellung und verwendung als glutamatantagonisten |
| UA54403C2 (uk) | 1996-10-01 | 2003-03-17 | Н'Юросерч А/С | Похідні індол-2,3-діон-3-оксиму, фармацевтична композиція, спосіб лікування розладу чи захворювання ссавців, у тому числі людини та спосіб одержання похідних індол-2,3-діон-3-оксиму |
| FR2768624B1 (fr) * | 1997-09-25 | 1999-11-12 | Oreal | Utilisation d'un inhibiteur d'acides amines excitateurs dans une composition cosmetique ou dermatologique pour peaux sensibles et composition obtenue |
| AU4910500A (en) * | 1999-05-19 | 2000-12-12 | Neurosearch A/S | Inhibitors of proton-gated cation channels and their use in the treatment of ischaemic disorders |
| PT1255734E (pt) | 2000-01-24 | 2006-09-29 | Neurosearch As | Derivados de isatina com actividade neurotrofica |
| WO2004039372A1 (en) | 2002-10-29 | 2004-05-13 | Sungkyunkwan University | Medicament component of berberine for the use of prevention and treatment of psycological dependence on and analgesic tolerance to morphine |
| CN101346375B (zh) | 2005-11-23 | 2013-04-10 | 阿罗斯药物有限责任公司 | 调节门离子通道用组合物和方法 |
| US9376391B2 (en) * | 2012-12-19 | 2016-06-28 | Bayer Cropscience Ag | Difluoromethyl-nicotinic-tetrahydronaphthyl carboxamides as fungicides |
| DE112015001003B4 (de) * | 2014-02-28 | 2024-05-29 | Sumitomo Chemical Company, Limited | Verfahren zur Herstellung von 2-(Halogenmethyl)-3-methylnitrobenzol |
| EA039557B1 (ru) * | 2016-03-17 | 2022-02-10 | Фмк Корпорейшн | Способ превращения s-энантиомера в его рацемическую форму |
| CN112266368B (zh) * | 2017-11-15 | 2024-03-19 | 中山光禾医疗科技有限公司 | 光交联水凝胶材料的制备、原料、产品及应用 |
| CN108912127B (zh) * | 2018-08-27 | 2019-12-10 | 青岛农业大学 | 一种基于靛红骨架的苯并[b,e]氮杂卓化合物及其制备方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE69677B1 (en) * | 1989-12-11 | 1996-10-02 | Neurosearch As | Isatine derivatives their preparation and use |
-
1992
- 1992-08-26 MX MX9204914A patent/MX9204914A/es not_active IP Right Cessation
- 1992-08-26 CA CA002076948A patent/CA2076948C/en not_active Expired - Fee Related
- 1992-08-27 CZ CZ94395A patent/CZ282759B6/cs not_active IP Right Cessation
- 1992-08-27 KR KR1019940700676A patent/KR100277481B1/ko not_active IP Right Cessation
- 1992-08-27 RU RU94019425/04A patent/RU2114827C1/ru not_active IP Right Cessation
- 1992-08-27 EP EP92114654A patent/EP0529636B1/de not_active Expired - Lifetime
- 1992-08-27 PL PL92302584A patent/PL170920B1/pl unknown
- 1992-08-27 JP JP50493393A patent/JP3170584B2/ja not_active Expired - Fee Related
- 1992-08-27 SK SK238-94A patent/SK280578B6/sk unknown
- 1992-08-27 WO PCT/EP1992/001999 patent/WO1993005043A1/en active IP Right Grant
- 1992-08-27 DE DE69229461T patent/DE69229461T2/de not_active Expired - Lifetime
- 1992-08-27 DK DK92114654T patent/DK0529636T3/da active
- 1992-08-27 HU HU9400595A patent/HUT70753A/hu unknown
- 1992-08-27 AT AT92114654T patent/ATE181552T1/de not_active IP Right Cessation
- 1992-08-27 GE GEAP19922683A patent/GEP20002329B/en unknown
- 1992-08-27 AU AU24820/92A patent/AU655672B2/en not_active Ceased
-
1994
- 1994-02-25 NO NO940676A patent/NO301117B1/no unknown
- 1994-02-25 FI FI940889A patent/FI107156B/fi active
-
1995
- 1995-06-21 HU HU95P/P00323P patent/HU211632A9/hu unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ATE181552T1 (de) | 1999-07-15 |
| PL170920B1 (pl) | 1997-02-28 |
| AU2482092A (en) | 1993-04-05 |
| RU2114827C1 (ru) | 1998-07-10 |
| AU655672B2 (en) | 1995-01-05 |
| DE69229461T2 (de) | 1999-10-21 |
| KR100277481B1 (ko) | 2001-02-01 |
| NO940676D0 (no) | 1994-02-25 |
| HU9400595D0 (en) | 1994-05-30 |
| EP0529636B1 (de) | 1999-06-23 |
| SK280578B6 (sk) | 2000-04-10 |
| HU211632A9 (en) | 1995-12-28 |
| NO301117B1 (no) | 1997-09-15 |
| WO1993005043A1 (en) | 1993-03-18 |
| SK23894A3 (en) | 1994-12-07 |
| CZ39594A3 (en) | 1994-11-16 |
| JPH06510056A (ja) | 1994-11-10 |
| GEP20002329B (en) | 2000-12-25 |
| FI940889A (fi) | 1994-02-25 |
| CA2076948C (en) | 2002-04-16 |
| FI107156B (fi) | 2001-06-15 |
| JP3170584B2 (ja) | 2001-05-28 |
| NO940676L (de) | 1994-04-27 |
| EP0529636A1 (de) | 1993-03-03 |
| CA2076948A1 (en) | 1993-03-01 |
| MX9204914A (es) | 1993-07-01 |
| FI940889A0 (fi) | 1994-02-25 |
| CZ282759B6 (cs) | 1997-09-17 |
| DE69229461D1 (de) | 1999-07-29 |
| HUT70753A (en) | 1995-10-30 |
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