DK0528931T3 - Humaniserede kimæriske anti-ICAM-1 antistoffer, fremgangsmåder til fremstilling deraf og anvendelse deraf - Google Patents

Humaniserede kimæriske anti-ICAM-1 antistoffer, fremgangsmåder til fremstilling deraf og anvendelse deraf

Info

Publication number
DK0528931T3
DK0528931T3 DK91909612T DK91909612T DK0528931T3 DK 0528931 T3 DK0528931 T3 DK 0528931T3 DK 91909612 T DK91909612 T DK 91909612T DK 91909612 T DK91909612 T DK 91909612T DK 0528931 T3 DK0528931 T3 DK 0528931T3
Authority
DK
Denmark
Prior art keywords
antibodies
icam
methods
infection
humanized
Prior art date
Application number
DK91909612T
Other languages
Danish (da)
English (en)
Inventor
John Robert George Road Adair
Martyn Kim Strawberry Robinson
Susan Margaret Bright
Robert A Rothlein
Robert George Road Stoken John
Kim Strawberry Vale Rob Martyn
Margaret Bright Susan
A Rothlein Robert
Original Assignee
Celltech Therapeutics Ltd
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celltech Therapeutics Ltd, Boehringer Ingelheim Pharma filed Critical Celltech Therapeutics Ltd
Application granted granted Critical
Publication of DK0528931T3 publication Critical patent/DK0528931T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2821—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against ICAM molecules, e.g. CD50, CD54, CD102
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK91909612T 1990-04-27 1991-04-29 Humaniserede kimæriske anti-ICAM-1 antistoffer, fremgangsmåder til fremstilling deraf og anvendelse deraf DK0528931T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB909009548A GB9009548D0 (en) 1990-04-27 1990-04-27 Chimeric antibody and method
PCT/US1991/002946 WO1991016928A1 (en) 1990-04-27 1991-04-29 Humanized chimeric anti-icam-1 antibodies, methods of preparation and use

Publications (1)

Publication Number Publication Date
DK0528931T3 true DK0528931T3 (da) 1999-04-19

Family

ID=10675133

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91909612T DK0528931T3 (da) 1990-04-27 1991-04-29 Humaniserede kimæriske anti-ICAM-1 antistoffer, fremgangsmåder til fremstilling deraf og anvendelse deraf

Country Status (14)

Country Link
EP (1) EP0528931B1 (es)
JP (1) JPH05507406A (es)
AT (1) ATE168013T1 (es)
AU (1) AU649682B2 (es)
BR (1) BR9106394A (es)
CA (1) CA2081479A1 (es)
DE (1) DE69129743T2 (es)
DK (1) DK0528931T3 (es)
ES (1) ES2118084T3 (es)
FI (1) FI924819A (es)
GB (1) GB9009548D0 (es)
HU (1) HUT66103A (es)
NO (2) NO924088L (es)
WO (1) WO1991016928A1 (es)

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Also Published As

Publication number Publication date
AU649682B2 (en) 1994-06-02
DE69129743D1 (de) 1998-08-13
ES2118084T3 (es) 1998-09-16
CA2081479A1 (en) 1991-10-28
ATE168013T1 (de) 1998-07-15
EP0528931A1 (en) 1993-03-03
WO1991016928A1 (en) 1991-11-14
DE69129743T2 (de) 1999-02-11
NO984136D0 (no) 1998-09-08
HU9203370D0 (en) 1993-01-28
NO924088D0 (no) 1992-10-22
AU7860391A (en) 1991-11-27
NO984136L (no) 1992-12-23
JPH05507406A (ja) 1993-10-28
FI924819A0 (fi) 1992-10-23
EP0528931A4 (en) 1993-04-28
GB9009548D0 (en) 1990-06-20
FI924819A (fi) 1992-10-23
HUT66103A (en) 1994-09-28
EP0528931B1 (en) 1998-07-08
NO924088L (no) 1992-12-23
BR9106394A (pt) 1993-04-27

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