TW200517124A - Fully human antibodies against human 4-1BB - Google Patents

Fully human antibodies against human 4-1BB

Info

Publication number
TW200517124A
TW200517124A TW093130653A TW93130653A TW200517124A TW 200517124 A TW200517124 A TW 200517124A TW 093130653 A TW093130653 A TW 093130653A TW 93130653 A TW93130653 A TW 93130653A TW 200517124 A TW200517124 A TW 200517124A
Authority
TW
Taiwan
Prior art keywords
human
antibodies against
fully
antibody
human antibodies
Prior art date
Application number
TW093130653A
Other languages
Chinese (zh)
Other versions
TWI332844B (en
Inventor
Maria Jure-Kunkel
Laura J Hefta
Marc Santoro
Subinay Ganguly
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37426115&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TW200517124(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of TW200517124A publication Critical patent/TW200517124A/en
Application granted granted Critical
Publication of TWI332844B publication Critical patent/TWI332844B/en

Links

Landscapes

  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Fully human antibodies and antigen-binding portions thereof that bind to human 4-1BB and that allow binding of human 4-1BB to a human 4-1BB ligand. In one aspect, the antibody is an IgG4 antibody. Also provided is a method for treating cancer in a subject comprising administering a therapeutically effective amount of the antibody to said subject.
TW093130653A 2003-10-10 2004-10-08 Fully human antibodies against human 4-1bb TWI332844B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US51019303P 2003-10-10 2003-10-10

Publications (2)

Publication Number Publication Date
TW200517124A true TW200517124A (en) 2005-06-01
TWI332844B TWI332844B (en) 2010-11-11

Family

ID=37426115

Family Applications (1)

Application Number Title Priority Date Filing Date
TW093130653A TWI332844B (en) 2003-10-10 2004-10-08 Fully human antibodies against human 4-1bb

Country Status (5)

Country Link
CN (1) CN1867585B (en)
AR (1) AR046094A1 (en)
PE (1) PE20050962A1 (en)
TW (1) TWI332844B (en)
ZA (1) ZA200602834B (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2614082T3 (en) * 2010-09-09 2018-11-26 Pfizer 4-1BB BINDING MOLECULES
KR101503341B1 (en) 2014-03-12 2015-03-18 국립암센터 Methods for isolation and proliferation of autologous cancer antigen-specific CD8+ T cells
JP2018520650A (en) * 2015-05-21 2018-08-02 アリゲーター・バイオサイエンス・アーベー Novel polypeptide
US10875926B2 (en) 2015-09-22 2020-12-29 Dingfu Biotarget Co., Ltd. Fully human antibody against human CD 137
GB201619648D0 (en) * 2016-11-21 2017-01-04 Alligator Bioscience Ab Novel antibodies and uses thereof
SG10201914064QA (en) 2017-01-06 2020-03-30 Eutilex Co Ltd Anti-human 4-1 bb antibodies and use thereof
JP7323513B2 (en) * 2017-06-25 2023-08-08 システィミューン， インク． ANTI-4-1BB ANTIBODY AND METHOD OF PRODUCTION AND USAGE THEREOF
MX2020000342A (en) * 2017-07-11 2020-08-17 Compass Therapeutics Llc Agonist antibodies that bind human cd137 and uses thereof.
CN111511762A (en) * 2017-08-21 2020-08-07 天演药业公司 anti-CD137 molecules and uses thereof
WO2019072274A1 (en) * 2017-10-12 2019-04-18 瑞阳(苏州)生物科技有限公司 Agonistic 4-1bb monoclonal antibody
CN109651507B (en) 2017-10-12 2021-11-26 瑞阳(苏州)生物科技有限公司 Excited 4-1BB monoclonal antibody
TWI701259B (en) * 2017-11-09 2020-08-11 大陸商上海懷越生物科技有限公司 4-1BB antibody and its preparation method and application
RU2020127196A (en) * 2018-01-22 2022-02-24 Цзянсу Хэнжуй Медицин Ко., Лтд. ANTIBODY AGAINST 4-1BB, ITS ANTIGEN-BINDING FRAGMENT AND ITS MEDICAL APPLICATIONS
WO2019148445A1 (en) 2018-02-02 2019-08-08 Adagene Inc. Precision/context-dependent activatable antibodies, and methods of making and using the same
US12054554B2 (en) 2018-04-10 2024-08-06 Wuxi Biologics (Shanghai) Co., Ltd. Monoclonal antibody against human 4-1BB, method for preparing the same, and use thereof
CN110357961B (en) * 2018-04-10 2022-08-23 无锡智康弘义生物科技有限公司 Anti-human 4-1BB monoclonal antibody, preparation method and application thereof
CN112867733B (en) * 2018-10-19 2023-01-06 苏州丁孚靶点生物技术有限公司 anti-CD 137 antibodies and uses thereof
CN111320691B (en) * 2018-12-17 2022-04-05 程联胜 Anti-human 4-1BB monoclonal antibody and application thereof
CN112010974B (en) * 2019-05-30 2022-08-09 山东博安生物技术股份有限公司 Antibody specifically binding to human 4-1BB and application thereof
CN113842456B (en) * 2020-06-28 2022-07-26 上海齐鲁制药研究中心有限公司 Anti-human 4-1BB monoclonal antibody preparation and application thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996029348A1 (en) * 1995-03-23 1996-09-26 Indiana University Foundation Monoclonal antibody against human receptor protein 4-1bb and methods of its use for treatment of diseases
NZ334691A (en) * 1996-10-11 2000-12-22 Bristol Myers Squibb Co Compositions of anti-4-1BB antibody effective for immunomodulation and treatment of T-cell autoimmune disease

Also Published As

Publication number Publication date
ZA200602834B (en) 2007-07-25
PE20050962A1 (en) 2005-11-17
AR046094A1 (en) 2005-11-23
CN1867585A (en) 2006-11-22
CN1867585B (en) 2011-02-09
TWI332844B (en) 2010-11-11

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Legal Events

Date Code Title Description
MM4A Annulment or lapse of patent due to non-payment of fees