PE20050962A1 - FULLY HUMAN ANTIBODIES VS HUMAN 4-1BB - Google Patents

FULLY HUMAN ANTIBODIES VS HUMAN 4-1BB

Info

Publication number
PE20050962A1
PE20050962A1 PE2004000974A PE2004000974A PE20050962A1 PE 20050962 A1 PE20050962 A1 PE 20050962A1 PE 2004000974 A PE2004000974 A PE 2004000974A PE 2004000974 A PE2004000974 A PE 2004000974A PE 20050962 A1 PE20050962 A1 PE 20050962A1
Authority
PE
Peru
Prior art keywords
human
seq
refers
amino acids
sequence
Prior art date
Application number
PE2004000974A
Other languages
Spanish (es)
Inventor
Maria Jure-Kunkel
Laura J Hefta
Marc Santoro
Subinay Ganguly
Edward L Halk
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37426115&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20050962(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of PE20050962A1 publication Critical patent/PE20050962A1/en

Links

Abstract

SE REFIERE A UN ANTICUERPO MONOCLONAL COMPLETAMENTE HUMANO Y PORCION DE ENLACE DE ANTIGENO DEL MISMO QUE SE ENLAZA ESPECIFICAMENTE A 4-1BB, QUE COMPRENDE UNA REGION VARIABLE DE CADENA LIGERA Y UN REGION VARIABLE DE CADENA PESADA, EN DONDE LA CADENA LIGERA COMPRENDE LOS RESIDUOS DE AMINOACIDOS 21-236 DE SEQ ID NO: 6 Y LA CADENA PESADA COMPRENDE LOS RESIDUOS DE AMINOACIDOS 20-467 DE SEQ IN NO: 3. TAMBIEN SE REFIERE A UN POLINUCLEOTIDO AISLADO QUE COMPRENDE UNA SECUENCIA DE NUCLEOTIDO QUE CODIFICA LA SECUENCIA DE AMINOACIDOS ANTERIORMENTE MENCIONADOS Y A UNA COMPOSICION FARMACEUTICA QUE LOS CONTIENE, EL CUAL SE UTILIZA EN EL TRATAMIENTO DEL CANCERIT REFERS TO A COMPLETELY HUMAN MONOCLONAL ANTIBODY AND ANTIGEN BINDING PORTION OF THE SAME THAT IS SPECIFICALLY LINKED TO 4-1BB, INCLUDING A VARIABLE LIGHT CHAIN REGION AND A HEAVY CHAIN VARIABLE REGION, WHERE THE LIGHT CHAIN RESIDES THEM AMINO ACIDS 21-236 OF SEQ ID NO: 6 AND THE HEAVY CHAIN INCLUDES THE RESIDUES OF AMINO ACIDS 20-467 OF SEQ IN NO: 3. ALSO REFERS TO AN ISOLATED POLYNUCLEOTIDE THAT INCLUDES A SEQUENCE OF NUCLEOTIDE THAT CODES THE LESSON SEQUENCE OF AMINO ACID AND TO A PHARMACEUTICAL COMPOSITION THAT CONTAINS THEM, WHICH IS USED IN THE TREATMENT OF CANCER

PE2004000974A 2003-10-10 2004-10-11 FULLY HUMAN ANTIBODIES VS HUMAN 4-1BB PE20050962A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US51019303P 2003-10-10 2003-10-10

Publications (1)

Publication Number Publication Date
PE20050962A1 true PE20050962A1 (en) 2005-11-17

Family

ID=37426115

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2004000974A PE20050962A1 (en) 2003-10-10 2004-10-11 FULLY HUMAN ANTIBODIES VS HUMAN 4-1BB

Country Status (5)

Country Link
CN (1) CN1867585B (en)
AR (1) AR046094A1 (en)
PE (1) PE20050962A1 (en)
TW (1) TWI332844B (en)
ZA (1) ZA200602834B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110357961A (en) * 2018-04-10 2019-10-22 无锡智康弘义生物科技有限公司 Anti-human 4-1BB monoclonal antibody and its preparation method and application

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2551963C2 (en) * 2010-09-09 2015-06-10 Пфайзер Инк. Molecules binding to 4-1bb
KR101503341B1 (en) 2014-03-12 2015-03-18 국립암센터 Methods for isolation and proliferation of autologous cancer antigen-specific CD8+ T cells
CN107709367A (en) * 2015-05-21 2018-02-16 鳄鱼生物科学公司 Novel polypeptide
WO2017049452A1 (en) * 2015-09-22 2017-03-30 苏州丁孚靶点生物技术有限公司 Fully human antibody against human cd137 and use thereof
GB201619648D0 (en) * 2016-11-21 2017-01-04 Alligator Bioscience Ab Novel antibodies and uses thereof
MX2019004692A (en) 2017-01-06 2019-11-08 Eutilex Co Ltd Anti-human 4-1 bb antibodies and use thereof.
JP7323513B2 (en) * 2017-06-25 2023-08-08 システィミューン， インク． ANTI-4-1BB ANTIBODY AND METHOD OF PRODUCTION AND USAGE THEREOF
SG10201913147WA (en) * 2017-07-11 2020-02-27 Compass Therapeutics Llc Agonist antibodies that bind human cd137 and uses thereof
WO2019036855A1 (en) * 2017-08-21 2019-02-28 Adagene Inc. Anti-cd137 molecules and use thereof
WO2019072274A1 (en) * 2017-10-12 2019-04-18 瑞阳(苏州)生物科技有限公司 Agonistic 4-1bb monoclonal antibody
CN109651507B (en) 2017-10-12 2021-11-26 瑞阳(苏州)生物科技有限公司 Excited 4-1BB monoclonal antibody
TWI701259B (en) * 2017-11-09 2020-08-11 大陸商上海懷越生物科技有限公司 4-1BB antibody and its preparation method and application
CN111065652A (en) * 2018-01-22 2020-04-24 江苏恒瑞医药股份有限公司 Anti-4-1 BB antibody, antigen binding fragment thereof, and medical use thereof
WO2019148445A1 (en) 2018-02-02 2019-08-08 Adagene Inc. Precision/context-dependent activatable antibodies, and methods of making and using the same
CN112867733B (en) * 2018-10-19 2023-01-06 苏州丁孚靶点生物技术有限公司 anti-CD 137 antibodies and uses thereof
CN111320691B (en) * 2018-12-17 2022-04-05 程联胜 Anti-human 4-1BB monoclonal antibody and application thereof
CN112010974B (en) * 2019-05-30 2022-08-09 山东博安生物技术股份有限公司 Antibody specifically binding to human 4-1BB and application thereof
CN113842456B (en) * 2020-06-28 2022-07-26 上海齐鲁制药研究中心有限公司 Anti-human 4-1BB monoclonal antibody preparation and application thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996029348A1 (en) * 1995-03-23 1996-09-26 Indiana University Foundation Monoclonal antibody against human receptor protein 4-1bb and methods of its use for treatment of diseases
WO1998016249A1 (en) * 1996-10-11 1998-04-23 Bristol-Myers Squibb Company Methods and compositions for immunomodulation

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110357961A (en) * 2018-04-10 2019-10-22 无锡智康弘义生物科技有限公司 Anti-human 4-1BB monoclonal antibody and its preparation method and application
CN110357961B (en) * 2018-04-10 2022-08-23 无锡智康弘义生物科技有限公司 Anti-human 4-1BB monoclonal antibody, preparation method and application thereof

Also Published As

Publication number Publication date
AR046094A1 (en) 2005-11-23
CN1867585A (en) 2006-11-22
CN1867585B (en) 2011-02-09
ZA200602834B (en) 2007-07-25
TW200517124A (en) 2005-06-01
TWI332844B (en) 2010-11-11

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