DK0477903T3 - Substituerede 4-amino-3-pyridinoler, fremgangsmåde til deres fremstilling og deres anvendelse som lægemidler - Google Patents
Substituerede 4-amino-3-pyridinoler, fremgangsmåde til deres fremstilling og deres anvendelse som lægemidlerInfo
- Publication number
- DK0477903T3 DK0477903T3 DK91116336.8T DK91116336T DK0477903T3 DK 0477903 T3 DK0477903 T3 DK 0477903T3 DK 91116336 T DK91116336 T DK 91116336T DK 0477903 T3 DK0477903 T3 DK 0477903T3
- Authority
- DK
- Denmark
- Prior art keywords
- loweralkyl
- chem
- hydrogen
- preparation
- pyridinols
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/26—Radicals substituted by halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Psychiatry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Surface Treatment Of Glass (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US58911390A | 1990-09-27 | 1990-09-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0477903T3 true DK0477903T3 (da) | 1996-07-29 |
Family
ID=24356648
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK91116336.8T DK0477903T3 (da) | 1990-09-27 | 1991-09-25 | Substituerede 4-amino-3-pyridinoler, fremgangsmåde til deres fremstilling og deres anvendelse som lægemidler |
Country Status (22)
| Country | Link |
|---|---|
| US (3) | US5821239A (cs) |
| EP (1) | EP0477903B1 (cs) |
| JP (1) | JP3090511B2 (cs) |
| KR (1) | KR100215357B1 (cs) |
| AT (1) | ATE136297T1 (cs) |
| AU (1) | AU637720B2 (cs) |
| CA (1) | CA2052433C (cs) |
| CZ (1) | CZ282002B6 (cs) |
| DE (1) | DE69118470T2 (cs) |
| DK (1) | DK0477903T3 (cs) |
| ES (1) | ES2085940T3 (cs) |
| FI (1) | FI914504A7 (cs) |
| GR (1) | GR3019742T3 (cs) |
| HU (1) | HUT60247A (cs) |
| IE (1) | IE73874B1 (cs) |
| IL (1) | IL99581A (cs) |
| NO (1) | NO913778L (cs) |
| NZ (1) | NZ239935A (cs) |
| PT (1) | PT99073B (cs) |
| TW (1) | TW200462B (cs) |
| YU (1) | YU158591A (cs) |
| ZA (1) | ZA917692B (cs) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6218383B1 (en) | 1998-08-07 | 2001-04-17 | Targacept, Inc. | Pharmaceutical compositions for the prevention and treatment of central nervous system disorders |
| FR2813891B1 (fr) * | 2000-09-14 | 2005-01-14 | Immunotech Sa | Reactif multifonctionnel pour erythrocytes mettant en jeu des carbamates et applications |
| DE10102791B4 (de) * | 2001-01-22 | 2004-04-15 | Ifm Electronic Gmbh | Elektrischer Meßumformer |
| US7279470B2 (en) * | 2001-12-14 | 2007-10-09 | Novo Nordisk A/S | Compounds and uses thereof for decreasing activity of hormone-sensitive lipase |
| KR100443983B1 (ko) | 2002-01-15 | 2004-08-09 | 삼성전자주식회사 | 냉장고 |
| US8007826B2 (en) | 2003-12-11 | 2011-08-30 | Acorda Therapeutics, Inc. | Sustained release aminopyridine composition |
| US8354437B2 (en) * | 2004-04-09 | 2013-01-15 | Acorda Therapeutics, Inc. | Method of using sustained release aminopyridine compositions |
| AU2006215080B2 (en) * | 2005-02-17 | 2011-03-10 | Astellas Pharma Inc. | Pyridyl non-aromatic nitrogenated heterocyclic-1-carboxylate ester derivative |
| UY32109A (es) * | 2008-09-10 | 2010-04-30 | Acorda Therapeutics Inc | Métodos para utilizar composiciones de liberación sostenida de aminopiridina |
| AU2011215870B2 (en) | 2010-02-09 | 2016-01-28 | The Johns Hopkins University | Methods and compositions for improving cognitive function |
| US20140206667A1 (en) | 2012-11-14 | 2014-07-24 | Michela Gallagher | Methods and compositions for treating schizophrenia |
| NZ708595A (en) | 2012-12-13 | 2019-06-28 | H Lundbeck As | Compositions comprising vortioxetine and donepezil |
| EP3827820A1 (en) | 2013-03-15 | 2021-06-02 | The Johns Hopkins University | Brivaracetam for improving cognitive function |
| CN105142623A (zh) | 2013-03-15 | 2015-12-09 | 艾吉因生物股份有限公司 | 用于改善认知功能的方法和组合物 |
| AU2016268096B2 (en) | 2015-05-22 | 2021-04-01 | Agenebio, Inc. | Extended release pharmaceutical compositions of levetiracetam |
| JP6899120B2 (ja) * | 2016-10-12 | 2021-07-07 | 株式会社ナノエッグ | アセチルコリンエステラーゼ（ＡＣｈＥ）阻害剤 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4179563A (en) * | 1978-05-19 | 1979-12-18 | Warner-Lambert Company | 3-Aryloxy-substituted-aminopyridines and methods for their production |
| US4734275A (en) * | 1983-08-19 | 1988-03-29 | Research Corporation | Anti-curare agents |
| DE3514073A1 (de) * | 1985-04-18 | 1986-10-23 | Hoechst Ag, 6230 Frankfurt | Mehrfach substituierte pyridin-1-oxide, verfahren zu ihrer herstellung, die sie enthaltenden arzneimittel und ihre verwendung |
| US4735958A (en) * | 1986-12-22 | 1988-04-05 | Warner-Lambert Company | Trans-6-[2-[2-(substituted-phenyl)-3- (or 4-) heteroaryl-5-substituted-1H-pyrrol-1-yl]-ethyl]tetrahydro-4-hydroxy-2H-pyran-2-one inhibitors of cholesterol biosynthesis |
| US4831044A (en) * | 1987-10-29 | 1989-05-16 | Ici Americas Inc. | Fungicidal pyridyl cyclopropane carboxamidines |
| US4994473A (en) * | 1987-11-17 | 1991-02-19 | Ici Americas Inc. | Pyridyl containing insecticides |
| EP0361489A3 (en) * | 1988-09-30 | 1991-06-12 | Chugai Seiyaku Kabushiki Kaisha | Novel 3,4-diaminoquinoline and pyridine compounds |
| DE68906647T2 (de) * | 1988-11-16 | 1993-10-07 | Hoechst Roussel Pharma | Hydroxy-1,2,3,4-tetrahydroaminoacridine, Verfahren für ihre Herstellung und ihre Verwendung als Arzneimittel. |
| US4931457B1 (en) * | 1989-06-28 | 1993-11-16 | Hoechst-Roussel Pharmaceuticals Incorporated | Naphthylamino-and naphthyloxy-pyridineamin compounds useful as topical antiinflammatory agents for the treatment of skin disorders |
-
1991
- 1991-08-31 TW TW080106907A patent/TW200462B/zh active
- 1991-09-25 EP EP91116336A patent/EP0477903B1/en not_active Expired - Lifetime
- 1991-09-25 CZ CS912936A patent/CZ282002B6/cs not_active IP Right Cessation
- 1991-09-25 DE DE69118470T patent/DE69118470T2/de not_active Expired - Fee Related
- 1991-09-25 ES ES91116336T patent/ES2085940T3/es not_active Expired - Lifetime
- 1991-09-25 NZ NZ239935A patent/NZ239935A/en unknown
- 1991-09-25 FI FI914504A patent/FI914504A7/fi not_active Application Discontinuation
- 1991-09-25 AT AT91116336T patent/ATE136297T1/de not_active IP Right Cessation
- 1991-09-25 DK DK91116336.8T patent/DK0477903T3/da active
- 1991-09-26 AU AU84756/91A patent/AU637720B2/en not_active Expired - Fee Related
- 1991-09-26 NO NO91913778A patent/NO913778L/no unknown
- 1991-09-26 PT PT99073A patent/PT99073B/pt not_active IP Right Cessation
- 1991-09-26 IL IL9958191A patent/IL99581A/en not_active IP Right Cessation
- 1991-09-26 YU YU158591A patent/YU158591A/sh unknown
- 1991-09-26 CA CA002052433A patent/CA2052433C/en not_active Expired - Fee Related
- 1991-09-26 IE IE338991A patent/IE73874B1/en not_active IP Right Cessation
- 1991-09-26 JP JP03273439A patent/JP3090511B2/ja not_active Expired - Fee Related
- 1991-09-26 HU HU913075A patent/HUT60247A/hu unknown
- 1991-09-26 ZA ZA917692A patent/ZA917692B/xx unknown
- 1991-09-27 KR KR1019910016850A patent/KR100215357B1/ko not_active Expired - Fee Related
-
1996
- 1996-02-16 US US08/602,693 patent/US5821239A/en not_active Expired - Fee Related
- 1996-04-24 GR GR960401135T patent/GR3019742T3/el unknown
-
1998
- 1998-06-02 US US09/088,928 patent/US5869480A/en not_active Expired - Fee Related
- 1998-06-02 US US09/088,926 patent/US5866565A/en not_active Expired - Fee Related
Also Published As
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