DK0470192T3 - Forbedret immunoassay, der indbefatter lyofiliseret reaktantblanding - Google Patents
Forbedret immunoassay, der indbefatter lyofiliseret reaktantblandingInfo
- Publication number
- DK0470192T3 DK0470192T3 DK90908003.8T DK90908003T DK0470192T3 DK 0470192 T3 DK0470192 T3 DK 0470192T3 DK 90908003 T DK90908003 T DK 90908003T DK 0470192 T3 DK0470192 T3 DK 0470192T3
- Authority
- DK
- Denmark
- Prior art keywords
- polyethylene glycol
- mixture
- isooctylphenyl ether
- reactant mixture
- sugar
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
- G01N33/535—Production of labelled immunochemicals with enzyme label or co-enzymes, co-factors, enzyme inhibitors or enzyme substrates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/962—Prevention or removal of interfering materials or reactants or other treatment to enhance results, e.g. determining or preventing nonspecific binding
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/963—Methods of stopping an enzyme reaction or stabilizing the test materials
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/975—Kit
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/807—Apparatus included in process claim, e.g. physical support structures
- Y10S436/808—Automated or kit
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/826—Additives, e.g. buffers, diluents, preservatives
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Engineering & Computer Science (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Detergent Compositions (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/344,575 US5102788A (en) | 1988-11-21 | 1989-04-28 | Immunoassay including lyophilized reactant mixture |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0470192T3 true DK0470192T3 (da) | 1997-10-27 |
Family
ID=23351108
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK90908003.8T DK0470192T3 (da) | 1989-04-28 | 1990-04-16 | Forbedret immunoassay, der indbefatter lyofiliseret reaktantblanding |
Country Status (9)
Country | Link |
---|---|
US (1) | US5102788A (fr) |
EP (1) | EP0470192B1 (fr) |
JP (1) | JP2823353B2 (fr) |
AT (1) | ATE159047T1 (fr) |
CA (1) | CA2053885A1 (fr) |
DE (1) | DE69031561T2 (fr) |
DK (1) | DK0470192T3 (fr) |
ES (1) | ES2110415T3 (fr) |
WO (1) | WO1990013637A1 (fr) |
Families Citing this family (45)
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US5376556A (en) * | 1989-10-27 | 1994-12-27 | Abbott Laboratories | Surface-enhanced Raman spectroscopy immunoassay |
US5252496A (en) | 1989-12-18 | 1993-10-12 | Princeton Biomeditech Corporation | Carbon black immunochemical label |
DE4034509A1 (de) * | 1990-10-30 | 1992-05-07 | Boehringer Mannheim Gmbh | Immunologisches praezipitationsverfahren zur bestimmung eines bindefaehigen analyten sowie reagenz zur durchfuehrung dieses verfahrens |
IT1245761B (it) * | 1991-01-30 | 1994-10-14 | Alfa Wassermann Spa | Formulazioni farmaceutiche contenenti glicosaminoglicani assorbibili per via orale. |
US6800738B1 (en) | 1991-06-14 | 2004-10-05 | Genentech, Inc. | Method for making humanized antibodies |
DE69220080T2 (de) * | 1991-10-11 | 1997-12-11 | Abbott Lab | Reagenzzusammensetzung in form von benutzer-einheiten für spezifische bindungstests |
ES2147185T3 (es) * | 1991-10-11 | 2000-09-01 | Abbott Lab | Composicion de reactivo en dosis unitaria para ensayos por union especifica. |
US5298406A (en) * | 1992-09-14 | 1994-03-29 | E. I. Du Pont De Nemours And Company | Formulation for stabilizing enzymatic activity and immunoreactivity of creatine kinase and creatine kinase isoenzymes |
US5354654A (en) * | 1993-07-16 | 1994-10-11 | The United States Of America As Represented By The Secretary Of The Navy | Lyophilized ligand-receptor complexes for assays and sensors |
WO1995006868A1 (fr) * | 1993-08-31 | 1995-03-09 | Boehringer Mannheim Corporation | Reactif et procede d'utilisation dudit reactif |
ATE235919T1 (de) * | 1994-06-02 | 2003-04-15 | Elan Drug Delivery Ltd | Methode zum verhindern der aggregation von proteinen/peptiden bei rehydratation oder auftauen |
US5681754A (en) * | 1996-06-07 | 1997-10-28 | Abbott Laboratories | Method for improving the performance of an immunoreagent in an immunoassay |
US5876944A (en) * | 1996-06-10 | 1999-03-02 | Bayer Corporation | Method for amplification of the response signal in a sandwich immunoassay |
US5895765A (en) * | 1997-06-30 | 1999-04-20 | Bayer Corporation | Method for the detection of an analyte by immunochromatography |
US6833275B1 (en) * | 1997-07-22 | 2004-12-21 | Roche Diagnostics Gmbh | Gold conjugates containing detergent |
DE19731469A1 (de) * | 1997-07-22 | 1999-01-28 | Boehringer Mannheim Gmbh | Detergenzhaltige Goldkonjugate |
FR2781055B1 (fr) * | 1998-07-09 | 2000-10-13 | Immunotech Sa | Reactif et methode pour la permeabilisation et l'identification des erythrocytes |
US7141436B2 (en) * | 1999-11-03 | 2006-11-28 | Science And Technology Corp. | Immunoassay and reagents and kits for performing the same |
US6699722B2 (en) | 2000-04-14 | 2004-03-02 | A-Fem Medical Corporation | Positive detection lateral-flow apparatus and method for small and large analytes |
AT5044U1 (de) * | 2001-05-10 | 2002-02-25 | Medsystems Diagnostics Gmbh | Quantitativer einschritt immuntest in lyophilisierter form |
US20030017620A1 (en) * | 2001-06-21 | 2003-01-23 | Carron Keith T. | Lyophilization of colloidal metals for surface enhanced Raman scattering |
US7776610B2 (en) * | 2003-05-07 | 2010-08-17 | University Of Wyoming | Cyanide and related species detection with metal surfaces |
DE10323901A1 (de) * | 2003-05-26 | 2005-01-05 | Institut Virion/Serion Gmbh | Verfahren und Testmittel zur Untersuchung und/oder zum Nachweis von Biomolekülen und/oder Wirkstoffen in Flüssigkeitsproben |
US20040241879A1 (en) * | 2003-06-02 | 2004-12-02 | Robinson Joseph R. | Assay device and method |
US7993933B2 (en) * | 2004-05-06 | 2011-08-09 | University Of Wyoming | Cyanide and related species detection with metal surfaces |
US20080227219A1 (en) * | 2004-11-17 | 2008-09-18 | Frank Gamez | Electrochemiluminescent assay |
US20060275841A1 (en) * | 2004-12-20 | 2006-12-07 | Martin Blankfard | Assay method and apparatus with reduced sample matrix effects |
US7763418B2 (en) * | 2005-07-05 | 2010-07-27 | Cytoskeleton, Inc. | Detection of Rho proteins |
GB0701253D0 (en) | 2007-01-23 | 2007-02-28 | Diagnostics For The Real World | Nucleic acid amplification and testing |
US7738094B2 (en) | 2007-01-26 | 2010-06-15 | Becton, Dickinson And Company | Method, system, and compositions for cell counting and analysis |
US7816135B2 (en) | 2007-07-05 | 2010-10-19 | Becton, Dickinson And Company | Method of analyzing lymphocytes |
WO2009020612A1 (fr) * | 2007-08-06 | 2009-02-12 | Stb Lifesaving Technologies, Inc. | Procédés et pansement pour refermer des plaies internes |
WO2010006201A2 (fr) * | 2008-07-10 | 2010-01-14 | Abaxis, Inc. | Procédés de réduction d'une interaction non spécifique dans des essais de nanoparticules métalliques |
EP2198964B8 (fr) * | 2008-11-06 | 2013-04-24 | F. Hoffmann-La Roche AG | Procédé destiné à la préparation d'un réactif séché dans un système microfluidique |
CA2742678C (fr) * | 2008-12-03 | 2020-03-31 | Abaxis, Inc. | Dosage a bande d'ecoulement lateral avec un conjugue immobilise |
WO2010107654A2 (fr) * | 2009-03-16 | 2010-09-23 | Abaxis, Inc. | Dispositif à flux divisé pour analyses de partenaires à liaison spécifique |
US8039272B2 (en) * | 2009-04-01 | 2011-10-18 | Nova Biomedical | Rapid quantification assay involving concentrated and ligand-coated gold colloid |
CN102004146B (zh) * | 2009-09-03 | 2014-09-10 | 艾博生物医药(杭州)有限公司 | 一种混合标记物质和标记方法及其应用 |
WO2011084697A2 (fr) | 2009-12-17 | 2011-07-14 | Abaxis, Inc. | Nouveaux essais de détection d'analytes dans des échantillons et trousses et compositions s'y rapportant |
WO2011160015A2 (fr) | 2010-06-17 | 2011-12-22 | Abaxis, Inc. | Rotors pour immunoessais |
US8956859B1 (en) | 2010-08-13 | 2015-02-17 | Aviex Technologies Llc | Compositions and methods for determining successful immunization by one or more vaccines |
JP6801381B2 (ja) * | 2016-11-07 | 2020-12-16 | 東ソー株式会社 | 凍結乾燥状態の検体前処理試薬 |
JP2017083461A (ja) * | 2016-12-21 | 2017-05-18 | イノーバ・バイオサイエンシズ・リミテッドInnova Biosciences Ltd | 共役反応 |
US11286526B2 (en) | 2017-05-19 | 2022-03-29 | Gen-Probe Incorporated | Dried compositions containing flap endonuclease |
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US3378443A (en) * | 1966-04-05 | 1968-04-16 | American Cyanamid Co | Anhydrous liquid suspensions of biologics |
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US3652761A (en) * | 1969-09-04 | 1972-03-28 | Corning Glass Works | Immunochemical composites and antigen or antibody purification therewith |
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DE2310964A1 (de) * | 1973-03-02 | 1974-09-05 | Schering Ag | Antigen- bzw. antigen-proteinkonjugatbeschichtete erythrocytenpraeparation |
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DE2460903C3 (de) * | 1974-12-21 | 1981-12-24 | Boehringer Mannheim Gmbh, 6800 Mannheim | Neue 3,3',5,5'-Tetraalkylbenzidine |
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DE229810T1 (de) * | 1985-07-09 | 1987-11-05 | Quadrant Bioresources Ltd., Soulbury, Leighton Buzzard, Bedfordshire | Beschuetzung von proteinen und aehnlichem. |
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-
1989
- 1989-04-28 US US07/344,575 patent/US5102788A/en not_active Expired - Fee Related
-
1990
- 1990-04-16 WO PCT/US1990/002064 patent/WO1990013637A1/fr active IP Right Grant
- 1990-04-16 ES ES90908003T patent/ES2110415T3/es not_active Expired - Lifetime
- 1990-04-16 EP EP90908003A patent/EP0470192B1/fr not_active Expired - Lifetime
- 1990-04-16 DK DK90908003.8T patent/DK0470192T3/da active
- 1990-04-16 CA CA002053885A patent/CA2053885A1/fr not_active Abandoned
- 1990-04-16 JP JP2506814A patent/JP2823353B2/ja not_active Expired - Lifetime
- 1990-04-16 DE DE69031561T patent/DE69031561T2/de not_active Expired - Fee Related
- 1990-04-16 AT AT90908003T patent/ATE159047T1/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DE69031561D1 (de) | 1997-11-13 |
EP0470192A4 (en) | 1992-03-11 |
WO1990013637A1 (fr) | 1990-11-15 |
EP0470192B1 (fr) | 1997-10-08 |
US5102788A (en) | 1992-04-07 |
ES2110415T3 (es) | 1998-02-16 |
DE69031561T2 (de) | 1998-02-19 |
ATE159047T1 (de) | 1997-10-15 |
EP0470192A1 (fr) | 1992-02-12 |
JPH05500854A (ja) | 1993-02-18 |
JP2823353B2 (ja) | 1998-11-11 |
CA2053885A1 (fr) | 1990-10-29 |
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