EP2198964B8 - Procédé destiné à la préparation d'un réactif séché dans un système microfluidique - Google Patents

Procédé destiné à la préparation d'un réactif séché dans un système microfluidique Download PDF

Info

Publication number
EP2198964B8
EP2198964B8 EP08019462.4A EP08019462A EP2198964B8 EP 2198964 B8 EP2198964 B8 EP 2198964B8 EP 08019462 A EP08019462 A EP 08019462A EP 2198964 B8 EP2198964 B8 EP 2198964B8
Authority
EP
European Patent Office
Prior art keywords
micro
providing
fluid system
dry reagent
reagent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Not-in-force
Application number
EP08019462.4A
Other languages
German (de)
English (en)
Other versions
EP2198964A1 (fr
EP2198964B1 (fr
Inventor
Valerie Dr. Winckler-Desprez
Manfred Augstein
Romi Roedl
Susanne Wuerl
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Roche Diagnostics GmbH
Original Assignee
F Hoffmann La Roche AG
Roche Diagnostics GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG, Roche Diagnostics GmbH filed Critical F Hoffmann La Roche AG
Priority to EP08019462.4A priority Critical patent/EP2198964B8/fr
Priority to US12/573,472 priority patent/US8790932B2/en
Priority to CA2684268A priority patent/CA2684268A1/fr
Priority to JP2009254147A priority patent/JP2010112953A/ja
Priority to CN200910212006A priority patent/CN101737989A/zh
Publication of EP2198964A1 publication Critical patent/EP2198964A1/fr
Publication of EP2198964B1 publication Critical patent/EP2198964B1/fr
Application granted granted Critical
Publication of EP2198964B8 publication Critical patent/EP2198964B8/fr
Not-in-force legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502707—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B5/00—Drying solid materials or objects by processes not involving the application of heat
    • F26B5/04—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum
    • F26B5/06—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/12—Specific details about manufacturing devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/16—Reagents, handling or storing thereof
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/2525—Stabilizing or preserving
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/2575—Volumetric liquid transfer

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Drying Of Solid Materials (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
EP08019462.4A 2008-11-06 2008-11-06 Procédé destiné à la préparation d'un réactif séché dans un système microfluidique Not-in-force EP2198964B8 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
EP08019462.4A EP2198964B8 (fr) 2008-11-06 2008-11-06 Procédé destiné à la préparation d'un réactif séché dans un système microfluidique
US12/573,472 US8790932B2 (en) 2008-11-06 2009-10-05 Method for providing a dried reagent in a microfluidic system and microfluidic system
CA2684268A CA2684268A1 (fr) 2008-11-06 2009-11-03 Procede de fourniture d'un reactif sec dans un systeme microfluidique et systeme microfluidique connexe
JP2009254147A JP2010112953A (ja) 2008-11-06 2009-11-05 微小流体システムにおける乾燥試薬の提供方法及び微小流体システム
CN200910212006A CN101737989A (zh) 2008-11-06 2009-11-06 在微流体系统中提供干燥试剂的方法和微流体系统

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP08019462.4A EP2198964B8 (fr) 2008-11-06 2008-11-06 Procédé destiné à la préparation d'un réactif séché dans un système microfluidique

Publications (3)

Publication Number Publication Date
EP2198964A1 EP2198964A1 (fr) 2010-06-23
EP2198964B1 EP2198964B1 (fr) 2013-01-02
EP2198964B8 true EP2198964B8 (fr) 2013-04-24

Family

ID=40445241

Family Applications (1)

Application Number Title Priority Date Filing Date
EP08019462.4A Not-in-force EP2198964B8 (fr) 2008-11-06 2008-11-06 Procédé destiné à la préparation d'un réactif séché dans un système microfluidique

Country Status (5)

Country Link
US (1) US8790932B2 (fr)
EP (1) EP2198964B8 (fr)
JP (1) JP2010112953A (fr)
CN (1) CN101737989A (fr)
CA (1) CA2684268A1 (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103097883B (zh) * 2010-03-09 2016-03-02 网络百奥有限公司 提供样本输入至结果输出处理的单体生物芯片以及制造方法
US8720036B2 (en) 2010-03-09 2014-05-13 Netbio, Inc. Unitary biochip providing sample-in to results-out processing and methods of manufacture
US9533280B2 (en) * 2012-06-22 2017-01-03 Praxair Technology, Inc. High rate compositions
US10946376B2 (en) 2013-07-05 2021-03-16 Thinxxs Microtechnology Ag Carrier element for introducing a dry substance into a flow cell
EP2821138B2 (fr) 2013-07-05 2022-02-09 Thinxxs Microtechnology Ag Cellule d'écoulement avec substance de séchage intégrée
US10300486B2 (en) * 2015-07-17 2019-05-28 Stat-Diagnostica & Innovation, S.L. Dry chemistry container
US11311885B2 (en) 2016-06-02 2022-04-26 Integrated Nano-Technologies, Inc. System and method for confining reagents within a fluidic device
WO2018194700A1 (fr) 2017-04-20 2018-10-25 Hewlett-Packard Development Company, L.P. Système de réaction microfluidique
DE102018200520A1 (de) * 2018-01-15 2019-07-18 Robert Bosch Gmbh Verfahren zum Bereitstellen einer Lösung der Substanz in einer mikrofluidischen Vorrichtung
CN109174217B (zh) * 2018-08-07 2019-12-31 浙江大学 用于合成反应中实现干燥过程的微流控芯片及其方法
WO2024038109A1 (fr) 2022-08-17 2024-02-22 Thinxxs Microtechnology Gmbh Cuve à circulation microfluidique, procédé de production, utilisation et dispositif d'analyse

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5102788A (en) * 1988-11-21 1992-04-07 Hygeia Sciences, Inc. Immunoassay including lyophilized reactant mixture
US5413732A (en) 1991-08-19 1995-05-09 Abaxis, Inc. Reagent compositions for analytical testing
US20030138819A1 (en) * 2001-10-26 2003-07-24 Haiqing Gong Method for detecting disease
WO2004055198A2 (fr) * 2002-12-12 2004-07-01 Chiron Corporation Dispositif et procede de test sanguin direct au moyen de micropuces
SE0300823D0 (sv) * 2003-03-23 2003-03-23 Gyros Ab Preloaded Microscale Devices
EP1896610A2 (fr) 2005-05-03 2008-03-12 Handylab, Inc. Granulés lyophilisés
US20070280857A1 (en) * 2006-06-02 2007-12-06 Applera Corporation Devices and Methods for Positioning Dried Reagent In Microfluidic Devices
EP1916524A1 (fr) 2006-09-27 2008-04-30 Roche Diagnostics GmbH Elément d'essai rotatif

Also Published As

Publication number Publication date
EP2198964A1 (fr) 2010-06-23
CA2684268A1 (fr) 2010-05-06
US8790932B2 (en) 2014-07-29
JP2010112953A (ja) 2010-05-20
CN101737989A (zh) 2010-06-16
EP2198964B1 (fr) 2013-01-02
US20100112717A1 (en) 2010-05-06

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