GB2014162A - A particulate reagent, (e.g.) for use in immunoassays - Google Patents

A particulate reagent, (e.g.) for use in immunoassays

Info

Publication number
GB2014162A
GB2014162A GB7903338A GB7903338A GB2014162A GB 2014162 A GB2014162 A GB 2014162A GB 7903338 A GB7903338 A GB 7903338A GB 7903338 A GB7903338 A GB 7903338A GB 2014162 A GB2014162 A GB 2014162A
Authority
GB
United Kingdom
Prior art keywords
immunoassays
substance
magnetically attractable
reagent
particulate reagent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB7903338A
Other versions
GB2014162B (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Corp
Original Assignee
Technicon Instruments Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Technicon Instruments Corp filed Critical Technicon Instruments Corp
Priority to GB7903338A priority Critical patent/GB2014162B/en
Publication of GB2014162A publication Critical patent/GB2014162A/en
Application granted granted Critical
Publication of GB2014162B publication Critical patent/GB2014162B/en
Expired legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G01N33/5434—Magnetic particles using magnetic particle immunoreagent carriers which constitute new materials per se
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2446/00—Magnetic particle immunoreagent carriers
    • G01N2446/20—Magnetic particle immunoreagent carriers the magnetic material being present in the particle core
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2446/00—Magnetic particle immunoreagent carriers
    • G01N2446/40—Magnetic particle immunoreagent carriers the magnetic material being dispersed in the monomer composition prior to polymerisation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2446/00—Magnetic particle immunoreagent carriers
    • G01N2446/80—Magnetic particle immunoreagent carriers characterised by the agent used to coat the magnetic particles, e.g. lipids
    • G01N2446/86—Magnetic particle immunoreagent carriers characterised by the agent used to coat the magnetic particles, e.g. lipids the coating being pre-functionalised for attaching immunoreagents, e.g. aminodextran
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2446/00—Magnetic particle immunoreagent carriers
    • G01N2446/80—Magnetic particle immunoreagent carriers characterised by the agent used to coat the magnetic particles, e.g. lipids
    • G01N2446/90—Magnetic particle immunoreagent carriers characterised by the agent used to coat the magnetic particles, e.g. lipids characterised by small molecule linker used to couple immunoreagents to magnetic particles

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Polymerisation Methods In General (AREA)
  • Peptides Or Proteins (AREA)

Abstract

This is formed by polymerizing one or more monomers in the presence of magnetically attractable solids, under conditions such that the material as formed contains free reactive groups capable of coupling directly with a reagent gent substance (such as a protein) to bind the substance to the material. Such materials are especially useful for making magnetically attractable particulate reagents for use in immunoassays.
GB7903338A 1978-02-13 1979-01-31 Particulate reagent for use in immunoassays Expired GB2014162B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB7903338A GB2014162B (en) 1978-02-13 1979-01-31 Particulate reagent for use in immunoassays

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB567178 1978-02-13
GB7903338A GB2014162B (en) 1978-02-13 1979-01-31 Particulate reagent for use in immunoassays

Publications (2)

Publication Number Publication Date
GB2014162A true GB2014162A (en) 1979-08-22
GB2014162B GB2014162B (en) 1982-08-25

Family

ID=26240058

Family Applications (1)

Application Number Title Priority Date Filing Date
GB7903338A Expired GB2014162B (en) 1978-02-13 1979-01-31 Particulate reagent for use in immunoassays

Country Status (1)

Country Link
GB (1) GB2014162B (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0177191A1 (en) * 1984-09-05 1986-04-09 Serono Diagnostics Partners (A Massachusetts Limited Partnership) Methods of assay
US6013531A (en) * 1987-10-26 2000-01-11 Dade International Inc. Method to use fluorescent magnetic polymer particles as markers in an immunoassay
EP1248110A3 (en) * 1997-11-18 2005-01-26 Bio-Rad Laboratories, Inc. Multiplex flow immunoassays with magnetic particles as solid phase

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0177191A1 (en) * 1984-09-05 1986-04-09 Serono Diagnostics Partners (A Massachusetts Limited Partnership) Methods of assay
US6013531A (en) * 1987-10-26 2000-01-11 Dade International Inc. Method to use fluorescent magnetic polymer particles as markers in an immunoassay
EP1248110A3 (en) * 1997-11-18 2005-01-26 Bio-Rad Laboratories, Inc. Multiplex flow immunoassays with magnetic particles as solid phase

Also Published As

Publication number Publication date
GB2014162B (en) 1982-08-25

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Legal Events

Date Code Title Description
732 Registration of transactions, instruments or events in the register (sect. 32/1977)
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19940131