DK0413487T3 - Fremgangsmåde og indretning til transdermal indgivelse af dexmedetomidin - Google Patents

Fremgangsmåde og indretning til transdermal indgivelse af dexmedetomidin

Info

Publication number
DK0413487T3
DK0413487T3 DK90308637.9T DK90308637T DK0413487T3 DK 0413487 T3 DK0413487 T3 DK 0413487T3 DK 90308637 T DK90308637 T DK 90308637T DK 0413487 T3 DK0413487 T3 DK 0413487T3
Authority
DK
Denmark
Prior art keywords
dexmedetomidine
transdermal administration
adhesive layer
therapeutic system
administering
Prior art date
Application number
DK90308637.9T
Other languages
Danish (da)
English (en)
Inventor
Gary W Cleary
Kenneth J Colley
Donald R Wilson
Risto Lammintausta
Harry Jalonen
Original Assignee
Orion Yhtymae Oy
Cygnus Therapeutic Systems
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orion Yhtymae Oy, Cygnus Therapeutic Systems filed Critical Orion Yhtymae Oy
Application granted granted Critical
Publication of DK0413487T3 publication Critical patent/DK0413487T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK90308637.9T 1989-08-18 1990-08-06 Fremgangsmåde og indretning til transdermal indgivelse af dexmedetomidin DK0413487T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/395,717 US5124157A (en) 1989-08-18 1989-08-18 Method and device for administering dexmedetomidine transdermally

Publications (1)

Publication Number Publication Date
DK0413487T3 true DK0413487T3 (da) 1995-07-17

Family

ID=23564195

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90308637.9T DK0413487T3 (da) 1989-08-18 1990-08-06 Fremgangsmåde og indretning til transdermal indgivelse af dexmedetomidin

Country Status (25)

Country Link
US (1) US5124157A (pt)
EP (1) EP0413487B1 (pt)
JP (1) JP3043064B2 (pt)
CN (1) CN1035922C (pt)
AT (1) ATE122899T1 (pt)
AU (1) AU639015B2 (pt)
BG (1) BG95935A (pt)
CA (1) CA2064687C (pt)
DD (1) DD297066A5 (pt)
DE (1) DE69019628T2 (pt)
DK (1) DK0413487T3 (pt)
ES (1) ES2072397T3 (pt)
FI (1) FI100857B (pt)
HU (1) HUT64223A (pt)
IE (1) IE67127B1 (pt)
LT (1) LT3753B (pt)
LV (1) LV10685B (pt)
NO (1) NO300408B1 (pt)
NZ (1) NZ234749A (pt)
PL (1) PL165023B1 (pt)
PT (1) PT95002B (pt)
RU (1) RU2098083C1 (pt)
UA (1) UA26988C2 (pt)
WO (1) WO1991002505A1 (pt)
ZA (1) ZA906539B (pt)

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US5217718A (en) * 1989-08-18 1993-06-08 Cygnus Therapeutic Systems Method and device for administering dexmedetomidine transdermally
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GB9614098D0 (en) 1996-07-05 1996-09-04 Orion Yhtymae Oy Transdermal delivery of levosimendan
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AR015744A1 (es) * 1998-04-01 2001-05-16 Orion Corp Uso de dexmedetomidina para sedacion en terapia intensiva
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ATE312606T1 (de) 1999-10-29 2005-12-15 Orion Corp Verwendung eines imidazolderivats zur behandlung oder verhütung von hypotension und schock
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US20030026830A1 (en) * 2001-05-08 2003-02-06 Thomas Lauterback Transdermal therapeutic system for parkinson's disease inducing high plasma levels of rotigotine
US20030027793A1 (en) * 2001-05-08 2003-02-06 Thomas Lauterback Transdermal treatment of parkinson's disease
US8246980B2 (en) * 2002-07-30 2012-08-21 Ucb Pharma Gmbh Transdermal delivery system
US8246979B2 (en) 2002-07-30 2012-08-21 Ucb Pharma Gmbh Transdermal delivery system for the administration of rotigotine
US8211462B2 (en) * 2002-07-30 2012-07-03 Ucb Pharma Gmbh Hot-melt TTS for administering rotigotine
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IL152574A (en) * 2002-10-31 2009-09-22 Transpharma Medical Ltd A system for passing through the skin of dry items or dried medicines
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DE102006054733A1 (de) * 2006-11-21 2008-05-29 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches Systems mit hoher Wirkstoffausnutzungsrate und Dosiergenauigkeit
US20090291127A1 (en) * 2008-05-21 2009-11-26 Jianye Wen Transdermal anti-dementia active agent formulations and methods for using the same
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US20130096170A1 (en) 2011-10-14 2013-04-18 Hospira, Inc. Methods of treating pediatric patients using dexmedetomidine
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TWI629066B (zh) * 2013-10-07 2018-07-11 帝國製藥美國股份有限公司 使用右美托咪啶經皮組成物用於治療注意力不足過動症、焦慮及失眠的方法及組成物
RU2018105761A (ru) * 2013-10-07 2019-02-26 ТЕЙКОКУ ФАРМА ЮЭсЭй, ИНК. Устройства для трансдермальной доставки дексмедетомидина и способы их применения
TWI624278B (zh) * 2013-10-07 2018-05-21 帝國製藥美國股份有限公司 使用非鎮靜性右美托咪啶經皮組成物用於治療戒斷症候群的方法及組成物
CN105764495A (zh) * 2013-10-07 2016-07-13 帝国制药美国公司 用于管理疼痛的包含右旋美托咪啶经皮组合物的方法及组合物
RU2648449C2 (ru) * 2013-10-07 2018-03-26 ТЕЙКОКУ ФАРМА ЮЭсЭй, ИНК. Способы и композиции для трансдермальной доставки неседативного количества дексмедетомидина
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Also Published As

Publication number Publication date
LV10685B (en) 1995-12-20
JP3043064B2 (ja) 2000-05-22
IE67127B1 (en) 1996-03-06
LV10685A (lv) 1995-06-20
BG95935A (bg) 1993-12-24
PL286525A1 (en) 1991-05-20
NO300408B1 (no) 1997-05-26
CN1049450A (zh) 1991-02-27
LTIP1773A (en) 1995-07-25
UA26988C2 (uk) 2000-02-28
JPH05503916A (ja) 1993-06-24
NZ234749A (en) 1992-03-26
CN1035922C (zh) 1997-09-24
PL165023B1 (pl) 1994-11-30
FI100857B (fi) 1998-03-13
IE902993A1 (en) 1991-02-27
HUT64223A (en) 1993-12-28
DE69019628D1 (de) 1995-06-29
AU639015B2 (en) 1993-07-15
ZA906539B (en) 1991-06-26
DE69019628T2 (de) 1995-09-28
AU6183490A (en) 1991-04-03
RU2098083C1 (ru) 1997-12-10
WO1991002505A1 (en) 1991-03-07
US5124157A (en) 1992-06-23
CA2064687C (en) 1998-04-21
ES2072397T3 (es) 1995-07-16
DD297066A5 (de) 1992-01-02
EP0413487B1 (en) 1995-05-24
FI920576A0 (fi) 1992-02-11
PT95002B (pt) 1997-10-31
EP0413487A1 (en) 1991-02-20
LT3753B (en) 1996-03-25
NO920521L (no) 1992-02-10
HU9200517D0 (en) 1992-05-28
PT95002A (pt) 1992-02-28
NO920521D0 (no) 1992-02-10
ATE122899T1 (de) 1995-06-15
CA2064687A1 (en) 1991-02-19

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