DK0411501T3 - Optimerede fermenteringsfremgangsmåder til fremstilling af fremmedproteriner i E. coli - Google Patents

Optimerede fermenteringsfremgangsmåder til fremstilling af fremmedproteriner i E. coli

Info

Publication number
DK0411501T3
DK0411501T3 DK90114473.3T DK90114473T DK0411501T3 DK 0411501 T3 DK0411501 T3 DK 0411501T3 DK 90114473 T DK90114473 T DK 90114473T DK 0411501 T3 DK0411501 T3 DK 0411501T3
Authority
DK
Denmark
Prior art keywords
lactose
limitation
coli
foreign proteins
preparation
Prior art date
Application number
DK90114473.3T
Other languages
Danish (da)
English (en)
Inventor
Mathias Dr Grote
Original Assignee
Behringwerke Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Behringwerke Ag filed Critical Behringwerke Ag
Application granted granted Critical
Publication of DK0411501T3 publication Critical patent/DK0411501T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli
    • C12N15/72Expression systems using regulatory sequences derived from the lac-operon
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4721Lipocortins

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Plant Pathology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
DK90114473.3T 1989-08-02 1990-07-27 Optimerede fermenteringsfremgangsmåder til fremstilling af fremmedproteriner i E. coli DK0411501T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3925550A DE3925550A1 (de) 1989-08-02 1989-08-02 Optimierte fermentationsverfahren zur herstellung von fremdproteinen in e.coli

Publications (1)

Publication Number Publication Date
DK0411501T3 true DK0411501T3 (da) 1995-01-16

Family

ID=6386347

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90114473.3T DK0411501T3 (da) 1989-08-02 1990-07-27 Optimerede fermenteringsfremgangsmåder til fremstilling af fremmedproteriner i E. coli

Country Status (11)

Country Link
EP (1) EP0411501B1 (ja)
JP (1) JP2977241B2 (ja)
KR (3) KR100190777B1 (ja)
AT (1) ATE111528T1 (ja)
AU (1) AU624982B2 (ja)
CA (1) CA2022487C (ja)
DE (2) DE3925550A1 (ja)
DK (1) DK0411501T3 (ja)
ES (1) ES2060876T3 (ja)
IE (1) IE65040B1 (ja)
PT (1) PT94876B (ja)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9215550D0 (en) * 1992-07-22 1992-09-02 Celltech Ltd Protein expression system
AT397812B (de) * 1992-12-18 1994-07-25 Polymun Scient Gmbh Verfahren zur expression von genen unter kontrolle des lac-operators
KR0151534B1 (ko) * 1995-10-30 1998-08-17 이종호 유기산 생성이 억제된 대장균 변이주
JP2006508643A (ja) * 2002-07-01 2006-03-16 アーキオン ライフ サイエンシーズ エルエルシー ディー/ビー/エー バイオ−テクニカル リソーセズ ディビジョン グルコサミンおよびn−アセチルグルコサミン製造のためのプロセスおよび材料
JPWO2011013721A1 (ja) * 2009-07-28 2013-01-10 三井化学株式会社 乳酸製造方法
JPWO2015178466A1 (ja) 2014-05-21 2017-04-20 味の素株式会社 フィブロイン様タンパク質の製造法
CN111850072B (zh) * 2019-04-29 2022-08-16 暨南大学 Peptibody多表位疫苗发酵生产工艺与应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4746608A (en) * 1983-08-22 1988-05-24 Kyowa Hakko Kogyo Co., Ltd. Process for producing peptides
CA1319630C (en) * 1987-02-19 1993-06-29 Satori Sone Method of regulating expression of a foreign gene by controlling the sugar concentration in a medium and a process of producing a foreign gene product thereby

Also Published As

Publication number Publication date
IE902785A1 (en) 1991-02-27
JPH0376595A (ja) 1991-04-02
EP0411501A1 (de) 1991-02-06
JP2977241B2 (ja) 1999-11-15
ES2060876T3 (es) 1994-12-01
PT94876B (pt) 1997-04-30
KR910004811A (ko) 1991-03-29
ATE111528T1 (de) 1994-09-15
PT94876A (pt) 1991-04-18
KR100190778B1 (en) 1999-06-01
KR100190779B1 (ko) 1999-06-01
CA2022487A1 (en) 1991-02-03
DE3925550A1 (de) 1991-02-07
DE3925550C2 (ja) 1991-08-08
KR100190777B1 (ko) 1999-06-01
AU6000590A (en) 1991-02-07
IE65040B1 (en) 1995-10-04
CA2022487C (en) 2001-12-11
DE59007117D1 (de) 1994-10-20
AU624982B2 (en) 1992-06-25
EP0411501B1 (de) 1994-09-14

Similar Documents

Publication Publication Date Title
DE69430919D1 (de) Eine phosphoenolpyruvat-carboxylasevariante, ihr gen und verfahren zur herstellung von aminosäuren
EP0187048A3 (en) Process for the production of soy hydrolysate, enzymatically modified soy protein and the use thereof as an egg white substitute
DK0616034T3 (da) Plasmid til fremstilling af CRM-protein og diphtheria toxin
DK0431350T3 (da) Ny polypeptidforbindelse og fremgangsmåde til fremstilling deraf
UA5954A1 (uk) Спосіб отримання (+)-4-ді-(н-пропіл)-аміно-6-карбамоіл-1,3,4,5-тетрагідробенз (с,д) індола або його фармацевтично придатної солі
EP0489711A3 (en) Method for producing human growth hormone
DK0411501T3 (da) Optimerede fermenteringsfremgangsmåder til fremstilling af fremmedproteriner i E. coli
ES2129749T3 (es) Vector de secrecion, microorganismos transformados que contienen el indicado vector y produccion de un producto a partir de dicho microorganismo.
MX9200126A (es) Proceso para la produccion de proteinas vegetales hidrolizadas utilizando acido clorhidrico gaseoso, y el producto asi obtenido
ATE129524T1 (de) Herstellung von copolymeren.
DK0575452T3 (da) Fremgangsmåde til fremstilling af vegetabilsk proteinhydrolysat
DE68926893D1 (de) Verfahren zur Herstellung von clavulanic Säure
DK461887D0 (da) Fremgangsmaade til selektivt at foroege andelen af enkelte hovedkomponenter af antibiotikum a 40926-kompleks
ATE57907T1 (de) Kontinuierliches verfahren zur herstellung von 1,2-diolen.
MX9200125A (es) Proceso para la produccion de proteinas hidrolizadas, y el producto asi obtenido
ES8705041A1 (es) Un metodo para producir interleuquina-2
DK0685492T3 (da) Fremgangsmåde til fremstilling af molekylært ensartede hyperpolymere hæmoglobiner
DE3686981D1 (de) Produktion eines proteins.
AU569677B1 (en) Production of cystine from cysteine obtained by the enzymatic or fermentative method
DE69121870D1 (de) Mutanter Stamm von Xanthomonas Campestris, Verfahren zur Herstellung von Xanthan und nichtviskoser Xanthan
ITMI913375A1 (it) Procedimento per la produzione di neuraminidasi
ATE154948T1 (de) Mikrobiologisches verfahren zur herstellung von 6-hydroxynikotinsäure
ATE155530T1 (de) Mikrobiologisches verfahren zur herstellung von 6-hydroxypicolinsäure
ATE83610T1 (de) Verfahren zur herstellung von kondensmilch.
AU2046888A (en) Process for the preparation of n6-benzyloxycarbonyl-2,6- diaminopimelamic acid in the l, l or d, d or racemic forms