DE775108T1 - Wasserlösliche organische salze von kreatin - Google Patents

Wasserlösliche organische salze von kreatin

Info

Publication number
DE775108T1
DE775108T1 DE0775108T DE95927700T DE775108T1 DE 775108 T1 DE775108 T1 DE 775108T1 DE 0775108 T DE0775108 T DE 0775108T DE 95927700 T DE95927700 T DE 95927700T DE 775108 T1 DE775108 T1 DE 775108T1
Authority
DE
Germany
Prior art keywords
creatine
salts according
anion
acid
water
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE0775108T
Other languages
English (en)
Inventor
Corona Lucio Del
Giampaolo Negrisoli
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Flamma SpA
Original Assignee
Flamma SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11369443&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE775108(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Flamma SpA filed Critical Flamma SpA
Publication of DE775108T1 publication Critical patent/DE775108T1/de
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/235—Saturated compounds containing more than one carboxyl group
    • C07C59/245—Saturated compounds containing more than one carboxyl group containing hydroxy or O-metal groups
    • C07C59/265—Citric acid
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/175—Amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C279/14—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
    • C07C57/13—Dicarboxylic acids
    • C07C57/145—Maleic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
    • C07C57/13—Dicarboxylic acids
    • C07C57/15—Fumaric acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/235—Saturated compounds containing more than one carboxyl group
    • C07C59/245—Saturated compounds containing more than one carboxyl group containing hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/235—Saturated compounds containing more than one carboxyl group
    • C07C59/245—Saturated compounds containing more than one carboxyl group containing hydroxy or O-metal groups
    • C07C59/255—Tartaric acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Food Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Nutrition Science (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Polymers & Plastics (AREA)
  • Mycology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Fodder In General (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • General Preparation And Processing Of Foods (AREA)

Claims (9)

FLAMMAS.P.A. DE /EP Q 775 Patentansprüche:
1. Salze von Kreatin mit der allgemeinen Formel I:
^C N CH7COOH A© (I)
H2N CH3
pi
worin A das Anion einer Mono-, Di- oder Tricarbonsäure darstellt.
2. Kreatinsalze nach Anspruch 1, worin A das Anion von Zitronensäure ist.
3. Kreatinsalze nach Anspruch 1, worin Aü das Anion der Maleinsäure ist.
4. Kreatinsalze nach Anspruch 1, worin Aö das Anion der Fumarsäure ist.
5. Kreatinsalze nach Anspruch 1, worin A das Anion der Weinsäure ist. 25
6. Kreatinsalze nach Anspruch 1, worin A das Anion der Apfelsäure ist.
7. Verfahren zur Herstellung der Salze nach den Ansprüchen 1-6, umfassend:
a) das gleichzeitige -Auflösen von Kreatin und der organischen Säure in
Wasser;
2 DE/ EP O 775 1 O&idigr;&iacgr; i
b) Konzentrieren der Lösung bis zur vollständigen Kristallisation und Trocknen des erhaltenen Produkts.
8. Verfahren zur Herstellung der Salze nach Anspruch 1-6 umfassend: 5
a) die Reaktion von Kreatin mit der organischen Säure in einem mit Wasser nicht mischbaren Lösemittel bei einer Temperatur von Raumtemperatur bis 5O0C;
b) Filtrieren und Trocknen des erhaltenen Produkts.
9. Verwendung der Salze nach den Ansprüchen 1 - 6 als Zusatz in diätetischen Zusammensetzungen und/oder Nahrungsmittelzusammensetzungen.
DE0775108T 1994-08-04 1995-07-21 Wasserlösliche organische salze von kreatin Pending DE775108T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITMI941693A IT1271687B (it) 1994-08-04 1994-08-04 Sali organici idrosolubili della creatina
PCT/EP1995/002897 WO1996004240A1 (en) 1994-08-04 1995-07-21 Hydrosoluble organic salts of creatine

Publications (1)

Publication Number Publication Date
DE775108T1 true DE775108T1 (de) 1998-03-12

Family

ID=11369443

Family Applications (2)

Application Number Title Priority Date Filing Date
DE0775108T Pending DE775108T1 (de) 1994-08-04 1995-07-21 Wasserlösliche organische salze von kreatin
DE69506882T Expired - Fee Related DE69506882T2 (de) 1994-08-04 1995-07-21 Wasserlösliche organische salze von kreatin

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69506882T Expired - Fee Related DE69506882T2 (de) 1994-08-04 1995-07-21 Wasserlösliche organische salze von kreatin

Country Status (8)

Country Link
US (1) US5973199A (de)
EP (1) EP0775108B1 (de)
AT (1) ATE174905T1 (de)
CA (1) CA2194218C (de)
DE (2) DE775108T1 (de)
ES (1) ES2107981T1 (de)
IT (1) IT1271687B (de)
WO (1) WO1996004240A1 (de)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9611356D0 (en) * 1996-05-31 1996-08-07 Howard Alan N Improvements in or relating to compositions containing Creatine, and other ergogenic compounds
US8128955B2 (en) 1996-05-31 2012-03-06 The Original Creatine Patent Company Food compositions containing creatine
US6168802B1 (en) 1996-05-31 2001-01-02 The Howard Foundation Compositions containing creatine and aloe vera extract
US6274161B1 (en) 1996-05-31 2001-08-14 The Howard Foundation Compositions containing creatine in suspension
US7150880B2 (en) 1996-05-31 2006-12-19 The Original Creatine Patent Co. Ltd. Compositions containing creatine and creatinine and a methyl xanthine
US6524611B2 (en) 1996-05-31 2003-02-25 The Howard Foundation Compositions containing creatine and creatinine
DE19653225A1 (de) * 1996-12-20 1998-06-25 Sueddeutsche Kalkstickstoff Kreatin-pyruvate und Verfahren zu deren Herstellung
TR199900470T2 (xx) * 1996-12-20 1999-06-21 Skw Trostberg Aktiengesellschaft Kreatin piruvatlar ve bunlar� �retmek i�in bir y�ntem.
DE19707694A1 (de) * 1997-02-26 1998-08-27 Sueddeutsche Kalkstickstoff Kreatin-ascorbate und Verfahren zu deren Herstellung
AU6726098A (en) * 1997-02-26 1998-09-18 Skw Trostberg Aktiengesellschaft Creatine-ascorbates, production process
US6211407B1 (en) 2000-05-03 2001-04-03 Pfanstiehl Laboratories, Inc. Dicreatine citrate and tricreatine citrate and method of making same
US6399661B1 (en) * 2000-06-26 2002-06-04 Jeffrey M. Golini Oral creatine supplement and method for making same
DE10065478C1 (de) * 2000-12-28 2002-08-29 Sueddeutsche Kalkstickstoff Kreatin/Citronensäure-Verbindung, Verfahren zu ihrer Herstellung und Verwendung
US20030013767A1 (en) * 2001-07-13 2003-01-16 Samuel Bessman Method of treating weight loss using creatine
DE10208568A1 (de) * 2002-02-27 2003-09-18 Degussa Bioactives Deutschland Verbindung, enthaltend Kreatin, eine Säure-Komponente und/oder einen Komplex-Bildner
US7301051B2 (en) * 2002-12-18 2007-11-27 Starmark Laboratories Creatine salts and method of making same
US7109373B2 (en) * 2002-12-18 2006-09-19 San Corporation Creatine salts and method of making same
US6838562B2 (en) * 2003-04-01 2005-01-04 Sal Abraham Process for preparing a creatine heterocyclic acid salt and method of use
US20080103202A1 (en) * 2004-11-08 2008-05-01 Chris Ferguson Method of preparing creatine ester salts and uses thereof.
US20060194877A1 (en) * 2005-02-07 2006-08-31 Gardiner Paul T Creatine hydroxycitric acids salts and methods for their production and use in individuals
DK1909601T3 (da) * 2005-08-02 2013-08-26 Alzchem Ag Flydende formulering baseret på en guanidineddikesyrekomponent
CA2642761A1 (en) * 2006-02-23 2007-08-30 Iomedix Sleep International Srl Compositions and methods for the induction and maintenance of quality sleep
US7329763B1 (en) 2006-09-11 2008-02-12 New Cell Formulations Ltd Creatine pyroglutamic acid salts and methods for their production and use in individuals
US20080153897A1 (en) * 2006-09-11 2008-06-26 New Cell Formulations Ltd. Creatine pyroglutamic acid salts and methods for their production and use in individuals
WO2008031184A1 (en) * 2006-09-11 2008-03-20 New Cell Formulations Ltd. Creatine pyroglutamic acid salts and methods for their production and use in individuals
CA2663141C (en) * 2006-09-11 2010-02-09 New Cell Formulations Ltd. Creatine pyroglutamic acid salts and methods for their production and use in individuals
US20090156648A1 (en) * 2007-12-12 2009-06-18 Iovate T. & P. Inc. Preparations containing pyridoxine and alpha-hydroxyisocaproic acid (HICA)
US8546369B2 (en) 2008-05-30 2013-10-01 Northern Innovations Holding Corp. Salts of creatine imino sugar amides
US20110123654A1 (en) * 2008-06-06 2011-05-26 Ralf Jaeger Synergistic enhancement of cellular ergogenic nutrient uptake, like creatine or carnitine, with tarragon
US8466198B2 (en) * 2008-09-02 2013-06-18 Bruce Kneller Compositions comprising creatine salts and methods of use thereof
US20090312419A1 (en) * 2009-08-12 2009-12-17 Kneller Bruce W CREATINE -ßALANINATE: A NOVEL SALT FOR INCREASING ATHLETIC PERFORMANCE
GB201801633D0 (en) * 2018-02-01 2018-03-21 Ogorman Edward Sports supplements based on liquid creatine
DE102022114966A1 (de) * 2022-06-14 2023-12-14 Alzchem Trostberg Gmbh Wasserlösliches Kreatin-Agglomerat

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1967400A (en) * 1930-03-27 1934-07-24 Schering Kahlbaum Ag Production of guanidino fatty acids
JPS536204A (en) * 1976-07-08 1978-01-20 Kubota Ltd Scum removing apparatus
DE2945790C2 (de) * 1978-11-20 1987-03-12 Tanabe Seiyaku Co., Ltd., Osaka Neutrales L-Ornithin-L-malat-dihydrat und neutrales L-Lysin-L-malat-monohydrat und Verfahren zu deren Herstellung
US5091171B2 (en) * 1986-12-23 1997-07-15 Tristrata Inc Amphoteric compositions and polymeric forms of alpha hydroxyacids and their therapeutic use
DE4123248C2 (de) * 1991-07-13 1996-03-07 Degussa Verfahren zur Herstellung von N-substituierten alpha-Aminosäuren und alpha-Aminosäure-Derivaten
GB9215746D0 (en) * 1992-07-24 1992-09-09 Hultman Eric A method of increasing creatine supply depot
JP3213666B2 (ja) * 1994-02-28 2001-10-02 治彦 末岡 クレアチン飲料の製造方法
US5627172A (en) * 1994-03-04 1997-05-06 Natural Supplement Association, Incorporated Method for reduction of serum blood lipids or lipoprotein fraction
US5489589A (en) * 1994-12-07 1996-02-06 Bristol-Myers Squibb Company Amino acid derivatives of paclitaxel

Also Published As

Publication number Publication date
IT1271687B (it) 1997-06-04
DE69506882D1 (de) 1999-02-04
US5973199A (en) 1999-10-26
CA2194218C (en) 1999-01-12
ITMI941693A1 (it) 1996-02-04
WO1996004240A1 (en) 1996-02-15
ES2107981T1 (es) 1997-12-16
EP0775108B1 (de) 1998-12-23
ATE174905T1 (de) 1999-01-15
ITMI941693A0 (it) 1994-08-04
EP0775108A1 (de) 1997-05-28
CA2194218A1 (en) 1996-02-15
DE69506882T2 (de) 1999-05-12

Similar Documents

Publication Publication Date Title
DE775108T1 (de) Wasserlösliche organische salze von kreatin
DE68918561T2 (de) Bleichzusammensetzung.
DE3782508D1 (de) Verfahren zur herstellung von 2-(imidazolin-2-yl)-pyridin- und -chinolin-3-carbonsaeuren.
DE60112309T2 (de) Verwendung von percarbaminsäure und diacylpercarbamaten und deren vorstufen
DE1569820B2 (de) Nitrofarbstoffe, verfahren zu ihrer herstellung und ihre verwendung zum faerben von haaren
EP0023335A1 (de) Neue N-Hydroxyalkylimidazolinderivate, deren Herstellung und Verwendung
DE2207287B2 (de) Verfahren zur Herstellung von Biscarboxyäthyl-germaniumsesquioxid
DE2045998C3 (de) Verfahren zum Trennen von DL-Cystein in die optischen Antipoden
DE68914861T2 (de) Verfahren zur Herstellung eines Copolymers aus zwei alpha-Aminsäuren.
DE1181908B (de) Verfahren zur Herstellung wasserloeslicher kapillaraktiver Carbonamidgruppen ent-haltender Polyester
DE2000204A1 (de) Verfahren zum Ausruesten von Wolle
DE2258411C3 (de) Verfahren zur Gewinnung von D-Penicillamin
DE1812937C3 (de) 4-(Ammoäthansulfonylamino)-antipyrine und Aminoäthansulfonyl-p-phenetidine sowie Verfahren zu ihrer Herstellung
AT205017B (de) Verfahern zur Herstellung neuer, substituierter Halbamide der Bernsteinsäure
DE60304713T2 (de) Verfahren zur Herstellung von Chelaten von Metallen mit organischen Säuren
AT325589B (de) Verfahren zur gewinnung von d-penicillamin
DE719198C (de) Verfahren zur Herstellung von wasserloeslichen Leukoestern von verkuepbaren Verbindungen
EP0320447A2 (de) Verfahren zur Herstellung von metallisierbaren Azofarbstoffen
DE3300142C2 (de) Verfahren zur Herstellung von 1,1'-Dinaphthyl-4,4', 5,5', 8,8'-hexacarbonsäure-Derivaten
DE568783C (de) Verfahren zur Darstellung von 2-Aroylbenzanthronen
ATE73129T1 (de) Verfahren zur herstellung von aktivierten nitrosocarbamaten.
CH215296A (de) Verfahren zur Herstellung eines Harnstoffderivates.
CH288729A (de) Verfahren zur Herstellung eines metallhaltigen Azofarbstoffes.
CH283649A (de) Verfahren zur Herstellung eines neuen Phenoxyacetamidins.
CH359444A (de) Verfahren zur Herstellung neuer Alkylenpolyaminderivate