DE69936982T2 - Turbulenz-mischkopf für gewebeklebstoff-applikator und sprühkopf für selbigen - Google Patents
Turbulenz-mischkopf für gewebeklebstoff-applikator und sprühkopf für selbigen Download PDFInfo
- Publication number
- DE69936982T2 DE69936982T2 DE69936982T DE69936982T DE69936982T2 DE 69936982 T2 DE69936982 T2 DE 69936982T2 DE 69936982 T DE69936982 T DE 69936982T DE 69936982 T DE69936982 T DE 69936982T DE 69936982 T2 DE69936982 T2 DE 69936982T2
- Authority
- DE
- Germany
- Prior art keywords
- adhesive
- mixing
- applicator
- components
- fluid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000002156 mixing Methods 0.000 title claims abstract description 208
- 239000003106 tissue adhesive Substances 0.000 title abstract description 17
- 238000005507 spraying Methods 0.000 title 1
- 239000012530 fluid Substances 0.000 claims abstract description 78
- 229960004072 thrombin Drugs 0.000 claims abstract description 7
- 108090000190 Thrombin Proteins 0.000 claims abstract description 6
- 239000000853 adhesive Substances 0.000 claims description 142
- 230000001070 adhesive effect Effects 0.000 claims description 142
- 239000007788 liquid Substances 0.000 claims description 51
- 239000007787 solid Substances 0.000 claims description 19
- 108010080379 Fibrin Tissue Adhesive Proteins 0.000 claims description 10
- 230000007246 mechanism Effects 0.000 claims description 6
- 108010049003 Fibrinogen Proteins 0.000 claims description 3
- 102000008946 Fibrinogen Human genes 0.000 claims description 3
- 229940012952 fibrinogen Drugs 0.000 claims description 3
- 238000007599 discharging Methods 0.000 claims description 2
- 239000013013 elastic material Substances 0.000 claims description 2
- 239000012190 activator Substances 0.000 claims 2
- 239000007921 spray Substances 0.000 abstract description 7
- 108010073385 Fibrin Proteins 0.000 abstract description 4
- 102000009123 Fibrin Human genes 0.000 abstract description 4
- BWGVNKXGVNDBDI-UHFFFAOYSA-N Fibrin monomer Chemical compound CNC(=O)CNC(=O)CN BWGVNKXGVNDBDI-UHFFFAOYSA-N 0.000 abstract description 4
- 229950003499 fibrin Drugs 0.000 abstract description 4
- 239000000565 sealant Substances 0.000 abstract description 3
- 230000009977 dual effect Effects 0.000 abstract 1
- 210000003128 head Anatomy 0.000 description 31
- 239000000463 material Substances 0.000 description 15
- 239000000203 mixture Substances 0.000 description 14
- 210000003811 finger Anatomy 0.000 description 13
- 210000003734 kidney Anatomy 0.000 description 12
- 210000000078 claw Anatomy 0.000 description 9
- 238000012360 testing method Methods 0.000 description 9
- 241000283973 Oryctolagus cuniculus Species 0.000 description 8
- 210000001519 tissue Anatomy 0.000 description 8
- 241001631457 Cannula Species 0.000 description 7
- 230000000740 bleeding effect Effects 0.000 description 7
- 230000000694 effects Effects 0.000 description 7
- 230000023597 hemostasis Effects 0.000 description 7
- 210000000952 spleen Anatomy 0.000 description 7
- 238000000034 method Methods 0.000 description 6
- 238000007789 sealing Methods 0.000 description 6
- 210000003813 thumb Anatomy 0.000 description 6
- -1 polytetrafluoroethylene Polymers 0.000 description 5
- 230000008859 change Effects 0.000 description 4
- 238000010276 construction Methods 0.000 description 4
- 238000004519 manufacturing process Methods 0.000 description 4
- 210000001331 nose Anatomy 0.000 description 4
- 230000015572 biosynthetic process Effects 0.000 description 3
- 239000003086 colorant Substances 0.000 description 3
- 238000005755 formation reaction Methods 0.000 description 3
- 239000003292 glue Substances 0.000 description 3
- 238000005259 measurement Methods 0.000 description 3
- 230000036961 partial effect Effects 0.000 description 3
- 229920001343 polytetrafluoroethylene Polymers 0.000 description 3
- 239000004810 polytetrafluoroethylene Substances 0.000 description 3
- 241001164374 Calyx Species 0.000 description 2
- 239000004743 Polypropylene Substances 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 238000004140 cleaning Methods 0.000 description 2
- 230000001427 coherent effect Effects 0.000 description 2
- 238000004891 communication Methods 0.000 description 2
- 230000000052 comparative effect Effects 0.000 description 2
- 230000008021 deposition Effects 0.000 description 2
- 238000006073 displacement reaction Methods 0.000 description 2
- 210000003746 feather Anatomy 0.000 description 2
- 230000013011 mating Effects 0.000 description 2
- 210000000056 organ Anatomy 0.000 description 2
- 239000004033 plastic Substances 0.000 description 2
- 229920003023 plastic Polymers 0.000 description 2
- 229920001155 polypropylene Polymers 0.000 description 2
- 230000004044 response Effects 0.000 description 2
- 229920002379 silicone rubber Polymers 0.000 description 2
- 239000004945 silicone rubber Substances 0.000 description 2
- 230000007480 spreading Effects 0.000 description 2
- 238000003892 spreading Methods 0.000 description 2
- 238000012549 training Methods 0.000 description 2
- 230000002792 vascular Effects 0.000 description 2
- 229920001817 Agar Polymers 0.000 description 1
- 241000283690 Bos taurus Species 0.000 description 1
- 206010010774 Constipation Diseases 0.000 description 1
- 101001094044 Mus musculus Solute carrier family 26 member 6 Proteins 0.000 description 1
- 229920002125 Sokalan® Polymers 0.000 description 1
- 230000003187 abdominal effect Effects 0.000 description 1
- 239000013543 active substance Substances 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 239000008272 agar Substances 0.000 description 1
- 239000002518 antifoaming agent Substances 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 239000011324 bead Substances 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 239000011230 binding agent Substances 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 239000005018 casein Substances 0.000 description 1
- BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 description 1
- 235000021240 caseins Nutrition 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 238000005345 coagulation Methods 0.000 description 1
- 230000015271 coagulation Effects 0.000 description 1
- 230000006835 compression Effects 0.000 description 1
- 238000007906 compression Methods 0.000 description 1
- 230000001010 compromised effect Effects 0.000 description 1
- 239000000356 contaminant Substances 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 230000005611 electricity Effects 0.000 description 1
- 229920006335 epoxy glue Polymers 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 210000003414 extremity Anatomy 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 239000012467 final product Substances 0.000 description 1
- 210000005224 forefinger Anatomy 0.000 description 1
- 239000007970 homogeneous dispersion Substances 0.000 description 1
- 238000010348 incorporation Methods 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000001746 injection moulding Methods 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 238000002406 microsurgery Methods 0.000 description 1
- 239000002991 molded plastic Substances 0.000 description 1
- 239000012778 molding material Substances 0.000 description 1
- 230000037023 motor activity Effects 0.000 description 1
- 238000010137 moulding (plastic) Methods 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 230000002829 reductive effect Effects 0.000 description 1
- 230000008439 repair process Effects 0.000 description 1
- 230000002441 reversible effect Effects 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 229920000260 silastic Polymers 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 238000010561 standard procedure Methods 0.000 description 1
- 238000013517 stratification Methods 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
- 229940075469 tissue adhesives Drugs 0.000 description 1
- 230000000451 tissue damage Effects 0.000 description 1
- 231100000827 tissue damage Toxicity 0.000 description 1
- 230000000699 topical effect Effects 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 238000011144 upstream manufacturing Methods 0.000 description 1
- 238000011179 visual inspection Methods 0.000 description 1
- 238000009736 wetting Methods 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05C—APPARATUS FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05C17/00—Hand tools or apparatus using hand held tools, for applying liquids or other fluent materials to, for spreading applied liquids or other fluent materials on, or for partially removing applied liquids or other fluent materials from, surfaces
- B05C17/005—Hand tools or apparatus using hand held tools, for applying liquids or other fluent materials to, for spreading applied liquids or other fluent materials on, or for partially removing applied liquids or other fluent materials from, surfaces for discharging material from a reservoir or container located in or on the hand tool through an outlet orifice by pressure without using surface contacting members like pads or brushes
- B05C17/00503—Details of the outlet element
- B05C17/00516—Shape or geometry of the outlet orifice or the outlet element
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/00491—Surgical glue applicators
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B7/00—Spraying apparatus for discharge of liquids or other fluent materials from two or more sources, e.g. of liquid and air, of powder and gas
- B05B7/02—Spray pistols; Apparatus for discharge
- B05B7/04—Spray pistols; Apparatus for discharge with arrangements for mixing liquids or other fluent materials before discharge
- B05B7/0408—Spray pistols; Apparatus for discharge with arrangements for mixing liquids or other fluent materials before discharge with arrangements for mixing two or more liquids
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05C—APPARATUS FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05C17/00—Hand tools or apparatus using hand held tools, for applying liquids or other fluent materials to, for spreading applied liquids or other fluent materials on, or for partially removing applied liquids or other fluent materials from, surfaces
- B05C17/005—Hand tools or apparatus using hand held tools, for applying liquids or other fluent materials to, for spreading applied liquids or other fluent materials on, or for partially removing applied liquids or other fluent materials from, surfaces for discharging material from a reservoir or container located in or on the hand tool through an outlet orifice by pressure without using surface contacting members like pads or brushes
- B05C17/00553—Hand tools or apparatus using hand held tools, for applying liquids or other fluent materials to, for spreading applied liquids or other fluent materials on, or for partially removing applied liquids or other fluent materials from, surfaces for discharging material from a reservoir or container located in or on the hand tool through an outlet orifice by pressure without using surface contacting members like pads or brushes with means allowing the stock of material to consist of at least two different components
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B2017/00017—Electrical control of surgical instruments
- A61B2017/00115—Electrical control of surgical instruments with audible or visual output
Landscapes
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Mechanical Engineering (AREA)
- Medical Informatics (AREA)
- Animal Behavior & Ethology (AREA)
- Geometry (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Surgical Instruments (AREA)
- Nozzles (AREA)
- Coating Apparatus (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7715698P | 1998-03-06 | 1998-03-06 | |
| US77156P | 1998-03-06 | ||
| US37160 | 1998-03-09 | ||
| US09/037,160 US6063055A (en) | 1997-04-14 | 1998-03-09 | Turbulence mixing head for a tissue sealant applicator and spray head for same |
| PCT/US1999/004830 WO1999044672A1 (en) | 1998-03-06 | 1999-03-05 | Turbulence mixing head for a tissue sealant applicator and spray head for same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69936982D1 DE69936982D1 (de) | 2007-10-11 |
| DE69936982T2 true DE69936982T2 (de) | 2008-05-15 |
Family
ID=26713859
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69936982T Expired - Lifetime DE69936982T2 (de) | 1998-03-06 | 1999-03-05 | Turbulenz-mischkopf für gewebeklebstoff-applikator und sprühkopf für selbigen |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP1059957B1 (enExample) |
| JP (1) | JP2002505169A (enExample) |
| AT (1) | ATE371472T1 (enExample) |
| AU (1) | AU745108B2 (enExample) |
| CA (1) | CA2322271C (enExample) |
| DE (1) | DE69936982T2 (enExample) |
| DK (1) | DK1059957T3 (enExample) |
| ES (1) | ES2293719T3 (enExample) |
| WO (1) | WO1999044672A1 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6585696B2 (en) | 2000-12-22 | 2003-07-01 | Baxter International, Inc. | Method and apparatus for applying a medically useful multiple component material |
| US7923431B2 (en) | 2001-12-21 | 2011-04-12 | Ferrosan Medical Devices A/S | Haemostatic kit, a method of preparing a haemostatic agent and a method of promoting haemostatis |
| MXPA05006193A (es) | 2002-12-11 | 2005-12-05 | Ferrosan As | Materiales basados en gelatina como hisopos. |
| AR054637A1 (es) | 2004-01-30 | 2007-07-11 | Ferrosan As | Aerosoles y composiciones hemostaticas |
| RU2369408C2 (ru) | 2004-07-09 | 2009-10-10 | Ферросан А/С | Гемостатическая композиция, включающая гиалуроновую кислоту |
| DE102006006904A1 (de) * | 2006-02-09 | 2007-08-23 | Universität Rostock | Neue Mittel zur Blutstillung und Klebstoffe für medizinische Anwendungen |
| CA2716872C (en) | 2008-02-29 | 2015-02-10 | Ferrosan Medical Devices A/S | Device for promotion of hemostasis and/or wound healing |
| EP2310075A2 (en) * | 2008-07-08 | 2011-04-20 | Hyperbranch Medical Technology, Inc. | Self-contained medical applicators for multiple component formulations, and methods of use thereof |
| CA2865349C (en) | 2012-03-06 | 2021-07-06 | Ferrosan Medical Devices A/S | Pressurized container containing haemostatic paste |
| RU2636240C2 (ru) | 2012-06-12 | 2017-11-21 | Ферросан Медикал Дивайсиз А/С | Сухая гемостатическая композиция |
| EP3010419B1 (en) | 2013-06-21 | 2020-05-20 | Ferrosan Medical Devices A/S | Vacuum expanded dry composition and syringe for retaining same |
| BR112016013322B1 (pt) | 2013-12-11 | 2020-07-21 | Ferrosan Medical Devices A/S | métodos para preparação de uma composição seca e para reconstituir uma composição seca, composição seca, uso de uma composição seca, e, kit |
| RU2715235C2 (ru) | 2014-10-13 | 2020-02-26 | Ферросан Медикал Дивайсиз А/С | Сухая композиция для использования при гемостазе и заживлении ран |
| CA2970710A1 (en) | 2014-12-24 | 2016-06-30 | Ferrosan Medical Devices A/S | Syringe for retaining and mixing first and second substances |
| CN107771093B (zh) | 2015-07-03 | 2021-06-15 | 弗罗桑医疗设备公司 | 用于混合两种组分和用于在存储条件下保持真空的注射器 |
| JP7002127B2 (ja) * | 2018-03-03 | 2022-01-20 | 武蔵エンジニアリング株式会社 | ピックアップ部材を備える吐出ヘッドおよび液体材料吐出装置 |
| EP3560427A1 (en) * | 2018-04-24 | 2019-10-30 | Gecko Biomedical | Applicator for depositing a layer of adhesive or sealant composition on a biological and/or prosthetic tissue |
| CN112368028A (zh) | 2018-05-09 | 2021-02-12 | 弗罗桑医疗设备公司 | 用于制备止血组合物的方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3556348A (en) * | 1968-05-20 | 1971-01-19 | Robert J Bristow | Fluid mixing and dispensing apparatus |
| US4067479A (en) * | 1975-07-31 | 1978-01-10 | Products Research & Chemical Corporation | Two part material meter-mix dispenser apparatus |
| US4040420A (en) * | 1976-04-22 | 1977-08-09 | General Dynamics | Packaging and dispensing kit |
| US4083474A (en) * | 1977-03-21 | 1978-04-11 | Weyerhaeuser Company | Applicator gun for multi-component resin systems |
| US4471887A (en) * | 1982-04-26 | 1984-09-18 | Component Management Corp. | Dispensing device |
| US4978336A (en) | 1987-09-29 | 1990-12-18 | Hemaedics, Inc. | Biological syringe system |
| US5226877A (en) | 1989-06-23 | 1993-07-13 | Epstein Gordon H | Method and apparatus for preparing fibrinogen adhesive from whole blood |
| US5116315A (en) | 1989-10-03 | 1992-05-26 | Hemaedics, Inc. | Biological syringe system |
| DE59509633D1 (de) | 1994-06-28 | 2001-10-31 | Aventis Behring Gmbh | Vorrichtung zum Versprühen eines Gemischs aus zwei Komponenten |
| JPH11506649A (ja) * | 1995-06-06 | 1999-06-15 | クウォンティック バイオメディカル パートナーズ | 傷シーラント調製物並びに適用デバイス及び方法 |
| JP3024765U (ja) * | 1995-11-17 | 1996-05-31 | 株式会社八光電機製作所 | 二薬液混合噴霧ノズル |
-
1999
- 1999-03-05 JP JP2000534269A patent/JP2002505169A/ja active Pending
- 1999-03-05 ES ES99911133T patent/ES2293719T3/es not_active Expired - Lifetime
- 1999-03-05 AT AT99911133T patent/ATE371472T1/de active
- 1999-03-05 AU AU29847/99A patent/AU745108B2/en not_active Ceased
- 1999-03-05 DK DK99911133T patent/DK1059957T3/da active
- 1999-03-05 EP EP99911133A patent/EP1059957B1/en not_active Expired - Lifetime
- 1999-03-05 WO PCT/US1999/004830 patent/WO1999044672A1/en not_active Ceased
- 1999-03-05 DE DE69936982T patent/DE69936982T2/de not_active Expired - Lifetime
- 1999-03-05 CA CA002322271A patent/CA2322271C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU745108B2 (en) | 2002-03-14 |
| AU2984799A (en) | 1999-09-20 |
| DE69936982D1 (de) | 2007-10-11 |
| JP2002505169A (ja) | 2002-02-19 |
| ES2293719T3 (es) | 2008-03-16 |
| DK1059957T3 (da) | 2008-01-02 |
| EP1059957A1 (en) | 2000-12-20 |
| EP1059957B1 (en) | 2007-08-29 |
| CA2322271C (en) | 2009-07-07 |
| EP1059957A4 (en) | 2004-07-21 |
| ATE371472T1 (de) | 2007-09-15 |
| CA2322271A1 (en) | 1999-09-10 |
| WO1999044672A1 (en) | 1999-09-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |