DE69930166T2 - Verfahren und zusammensetzungen für impfung mit dem pseudomonas aeruginosa v-antigen - Google Patents

Verfahren und zusammensetzungen für impfung mit dem pseudomonas aeruginosa v-antigen Download PDF

Info

Publication number
DE69930166T2
DE69930166T2 DE69930166T DE69930166T DE69930166T2 DE 69930166 T2 DE69930166 T2 DE 69930166T2 DE 69930166 T DE69930166 T DE 69930166T DE 69930166 T DE69930166 T DE 69930166T DE 69930166 T2 DE69930166 T2 DE 69930166T2
Authority
DE
Germany
Prior art keywords
pcrv
infection
antigen
pseudomonas aeruginosa
antibody
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69930166T
Other languages
German (de)
English (en)
Other versions
DE69930166D1 (de
Inventor
W. Dara West Allis FRANK
L. Timothy Hanover YAHR
Teiji San Francisco SAWA
Jeanine San Francisco WIENER-KRONISH
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MCW Research Foundation Inc Milwaukee
University of California
Medical College of Wisconsin Research Foundation Inc
University of California Berkeley
University of California San Diego UCSD
Original Assignee
MCW Research Foundation Inc Milwaukee
University of California
Medical College of Wisconsin Research Foundation Inc
University of California Berkeley
University of California San Diego UCSD
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MCW Research Foundation Inc Milwaukee, University of California, Medical College of Wisconsin Research Foundation Inc, University of California Berkeley, University of California San Diego UCSD filed Critical MCW Research Foundation Inc Milwaukee
Publication of DE69930166D1 publication Critical patent/DE69930166D1/de
Application granted granted Critical
Publication of DE69930166T2 publication Critical patent/DE69930166T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/104Pseudomonadales, e.g. Pseudomonas
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/21Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pseudomonadaceae (F)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911Bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/21Assays involving biological materials from specific organisms or of a specific nature from bacteria from Pseudomonadaceae (F)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00Immunoassays for the detection of microorganisms
    • G01N2469/20Detection of antibodies in sample from host which are directed against antigens from microorganisms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • General Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Food Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
DE69930166T 1998-11-25 1999-11-23 Verfahren und zusammensetzungen für impfung mit dem pseudomonas aeruginosa v-antigen Expired - Lifetime DE69930166T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US10995298P 1998-11-25 1998-11-25
US109952P 1998-11-25
US12679499P 1999-03-30 1999-03-30
US126794P 1999-03-30
PCT/US1999/027796 WO2000033872A2 (en) 1998-11-25 1999-11-23 Method of and compositions for immunization with the pseudomonas v antigen

Publications (2)

Publication Number Publication Date
DE69930166D1 DE69930166D1 (de) 2006-04-27
DE69930166T2 true DE69930166T2 (de) 2006-12-14

Family

ID=26807543

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69930166T Expired - Lifetime DE69930166T2 (de) 1998-11-25 1999-11-23 Verfahren und zusammensetzungen für impfung mit dem pseudomonas aeruginosa v-antigen

Country Status (10)

Country Link
US (2) US6309651B1 (https=)
EP (2) EP1666058B1 (https=)
JP (2) JP4707234B2 (https=)
AT (2) ATE318613T1 (https=)
AU (1) AU3580800A (https=)
CA (1) CA2318536C (https=)
DE (1) DE69930166T2 (https=)
DK (1) DK1049488T3 (https=)
ES (2) ES2379801T3 (https=)
WO (1) WO2000033872A2 (https=)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002064161A2 (en) * 2001-01-26 2002-08-22 Mcw Research Foundation, Inc. Method and compositions for immunization with the pseudomonas v antigen
AU2007231760B2 (en) * 2001-01-26 2009-10-29 Mcw Research Foundation, Inc. Method and compositions for immunization with the pseudomonas V antigen
DE10294091D2 (de) * 2001-09-13 2004-08-05 Hannover Med Hochschule Phänotyp bestimmende Virulenzgene von Pseudomonas aeruginosa zur Kolonisation und Persistenz in Mensch, Tier und Pflanze, Verwendungen der Gene und zugehörigen Proteine
AU2003226441A1 (en) * 2002-01-11 2003-07-24 Cornell Research Foundation, Inc. Methods of identifying putative effector proteins
EP1528935B1 (en) 2002-08-13 2012-03-21 Haptogen Ltd Methods for the treatment of an infectious bacterial disease with an anti-lactone or lactone derived signal molecules antibody
EP1761561B1 (en) * 2004-01-20 2015-08-26 KaloBios Pharmaceuticals, Inc. Antibody specificity transfer using minimal essential binding determinants
GB0407008D0 (en) 2004-03-27 2004-04-28 Haptogen Ltd Methods for inducing rapid cell death (autolysis) in infectious bacteria
GB0410958D0 (en) 2004-05-15 2004-06-16 Haptogen Ltd Methods for reducing biofilm formation in infectious bacteria
WO2007049770A1 (ja) 2005-10-28 2007-05-03 Meiji Seika Kaisha, Ltd. 緑膿菌の外膜タンパク質pa5158
CN101454446A (zh) 2006-03-30 2009-06-10 明治制果株式会社 绿脓杆菌的外膜蛋白pa0427
WO2009005040A1 (ja) * 2007-06-29 2009-01-08 Meiji Seika Kaisha Ltd. 緑膿菌の外膜タンパク質pa4710
BRPI0819598A2 (pt) 2007-11-30 2017-05-09 Kalobios Pharmaceuticals Inc anticorpos para o antígeno pcrv da pseudomonas aeruginosa
EP2236515A4 (en) * 2007-12-25 2012-10-31 Meiji Seika Kaisha COMPONENT PROTEIN PA1698 FOR PSEUDOMONAS AERUGINOSA TYPE-III SECRETION SYSTEM
EA020544B1 (ru) * 2008-01-10 2014-12-30 Шионоги Энд Ко., Лтд. АНТИТЕЛА ПРОТИВ PcrV
CA2751433A1 (en) 2009-02-04 2010-08-12 Kalobios Pharmaceuticals, Inc. Combination antibiotic and antibody therapy for the treatment of pseudomonas aeruginosa infection
SG174225A1 (en) 2009-03-11 2011-10-28 Shionogi & Co Humanized pcrv antibody having anti-pseudomonal activity
WO2011087799A1 (en) * 2009-12-22 2011-07-21 Kalobios Pharmaceuticals, Inc. A method of treating a staphylococcus infection in a patient having a low-level pathogenic pseudomonas aeruginosa infection
KR20140064768A (ko) * 2011-07-01 2014-05-28 더 트러스티스 오브 더 유니버시티 오브 펜실바니아 항-프로퍼딘 항체 및 그의 용도
HRP20201370T1 (hr) 2011-11-07 2020-11-27 Medimmune Limited Kombinacijske terapije koje koriste anti-pseudomonas psl i pcrv vezujuće molekule
CA2887050A1 (en) 2012-10-04 2014-04-10 Novelmed Therapeutics, Inc. Alternative pathway specific antibodies for treating hemolytic diseases
CN110028559B (zh) * 2019-04-15 2022-06-10 中国人民解放军陆军军医大学 一种铜绿假单胞菌疫苗重组蛋白及其编码基因和它们的应用
US20220378902A1 (en) * 2019-08-22 2022-12-01 Sichuan University Bacterial membrane vesicles, and separation and preparation system and method therefor
US20230071019A1 (en) * 2019-12-04 2023-03-09 The Research Foundation For The State University Of New York Compositions and methods for reducing off-target toxicity of antibody drug conjugates

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3178014B2 (ja) * 1991-07-05 2001-06-18 東ソー株式会社 Rnaの測定方法
US5599665A (en) * 1993-12-21 1997-02-04 Mcw Research Foundation Pseudomonas aeruginosa nucleic acids encoding exoenzyme S activity and use thereof in detecting pseudomonas aeruginosa infection

Also Published As

Publication number Publication date
ES2255329T3 (es) 2006-06-16
EP1666058A3 (en) 2008-03-12
DE69930166D1 (de) 2006-04-27
CA2318536C (en) 2009-11-17
US6827935B2 (en) 2004-12-07
AU3580800A (en) 2000-06-26
JP2002531522A (ja) 2002-09-24
CA2318536A1 (en) 2000-06-15
JP2011068672A (ja) 2011-04-07
EP1049488A1 (en) 2000-11-08
WO2000033872A3 (en) 2000-10-19
ATE539349T1 (de) 2012-01-15
ATE318613T1 (de) 2006-03-15
WO2000033872A2 (en) 2000-06-15
EP1666058A2 (en) 2006-06-07
US6309651B1 (en) 2001-10-30
EP1666058B1 (en) 2011-12-28
EP1049488B1 (en) 2006-03-01
JP4707234B2 (ja) 2011-06-22
ES2379801T3 (es) 2012-05-03
US20040208888A1 (en) 2004-10-21
DK1049488T3 (da) 2006-06-26
WO2000033872A9 (en) 2000-12-14

Similar Documents

Publication Publication Date Title
DE69930166T2 (de) Verfahren und zusammensetzungen für impfung mit dem pseudomonas aeruginosa v-antigen
DE60216564T2 (de) Verfahren und zusammensetzungen für immunisierung mit dem pseudomonas antigen
Wunder Jr et al. A novel flagellar sheath protein, FcpA, determines filament coiling, translational motility and virulence for the Leptospira spirochete
DE69735715T2 (de) Cholin-bindendes Protein, welches als gegen Pneumokokken gerichtetes Vakzin verwendet wird
Hall et al. Natural killer cells protect against mucosal and systemic infection with the enteric pathogen Citrobacter rodentium
DE69032408T2 (de) Kreuzschützende salmonella impfstoffe
Guo et al. Safety, protective immunity, and DIVA capability of a rough mutant Salmonella Pullorum vaccine candidate in broilers
DE69925585T2 (de) Bakterien abgeschwächt durch eine nicht revertierende mutation in jeden der aroc, ompf und ompc gene, verwendbar als impfstoff
DE69834194T2 (de) Oberfläche-exponierte proteine von chlamydia pneumoniae
DE69434796T2 (de) Chlamydia impfstoff enthaltend anti-idiotypische antikörper
CH676606A5 (https=)
Saadati et al. Characterisation of the leukotoxin produced by different strains of Pasteurella haemolytica
DE60226057T2 (de) Geflügelkrankheit verursachendes bakterium und daraus stammender impfstoff
DE3685700T2 (de) E87ag-antigen des pseudomonas aeruginosa, monoklonale antikoerper dagegen und hybridom.
DE69221120T2 (de) Rekombinanter lebender Impfstoff gegen Gram-negative enterische Pathogene
Silva et al. The protective effect of vaccination against experimental pneumonia in cattle with Haemophilus somnus outer membrane antigens and interference by lipopolysaccharide
DE69935323T2 (de) Moraxella catharralis proteine
Gross Effect of adrenal blocking chemicals on viral and respiratory infections of chickens
WO2001042790A2 (de) Mittel und verfahren zur diagnose von lyme borreliose sowie borreliose-impfstoff
AU2007231760A1 (en) Method and compositions for immunization with the pseudomonas V antigen
DE69831888T2 (de) Nicht pathogener mutanter E. coli Stamm, Verfahren zur dessen Herstellung und Verwendung
DE102005037796A1 (de) Testsystem zum Nachweis von Salmonellen
Renuka Immune response of bighorn sheep to Mannheimia haemolytica
DE10260264A1 (de) Verfahren und Zelllinie zur Identifizierung proliferationshemmender, anti-inflammatorischer oder proliferationsfördender Wirkstoffe
DE102008010727A1 (de) Verfahren zur aktiven Immunisierung auf der Grundlage von bakteriellen O-Antigenen

Legal Events

Date Code Title Description
8364 No opposition during term of opposition