JP4707234B2 - シュードモナスv抗原を用いる免疫化のための組成物 - Google Patents

シュードモナスv抗原を用いる免疫化のための組成物 Download PDF

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JP4707234B2
JP4707234B2 JP2000586362A JP2000586362A JP4707234B2 JP 4707234 B2 JP4707234 B2 JP 4707234B2 JP 2000586362 A JP2000586362 A JP 2000586362A JP 2000586362 A JP2000586362 A JP 2000586362A JP 4707234 B2 JP4707234 B2 JP 4707234B2
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pcrv
infection
antigen
composition
protein
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JP2002531522A (ja
JP2002531522A5 (https=
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ダラ ダブリユー. フランク,
チモシー エル. イヤー,
テイジ サワ,
ジヤニネ ウイーナー−クロニツシ,
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エムシーダブリユー リサーチ フオンデーシヨン インコーポレーテツド
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/104Pseudomonadales, e.g. Pseudomonas
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/21Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pseudomonadaceae (F)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911Bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/21Assays involving biological materials from specific organisms or of a specific nature from bacteria from Pseudomonadaceae (F)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00Immunoassays for the detection of microorganisms
    • G01N2469/20Detection of antibodies in sample from host which are directed against antigens from microorganisms

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • General Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Food Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
JP2000586362A 1998-11-25 1999-11-23 シュードモナスv抗原を用いる免疫化のための組成物 Expired - Fee Related JP4707234B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US10995298P 1998-11-25 1998-11-25
US60/109,952 1998-11-25
US12679499P 1999-03-30 1999-03-30
US60/126,794 1999-03-30
PCT/US1999/027796 WO2000033872A2 (en) 1998-11-25 1999-11-23 Method of and compositions for immunization with the pseudomonas v antigen

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2010273433A Division JP2011068672A (ja) 1998-11-25 2010-12-08 シュードモナス・アエルギノーザ感染を診断するための組成物

Publications (3)

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JP2002531522A JP2002531522A (ja) 2002-09-24
JP2002531522A5 JP2002531522A5 (https=) 2007-01-25
JP4707234B2 true JP4707234B2 (ja) 2011-06-22

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JP2000586362A Expired - Fee Related JP4707234B2 (ja) 1998-11-25 1999-11-23 シュードモナスv抗原を用いる免疫化のための組成物
JP2010273433A Ceased JP2011068672A (ja) 1998-11-25 2010-12-08 シュードモナス・アエルギノーザ感染を診断するための組成物

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JP2010273433A Ceased JP2011068672A (ja) 1998-11-25 2010-12-08 シュードモナス・アエルギノーザ感染を診断するための組成物

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Country Link
US (2) US6309651B1 (https=)
EP (2) EP1666058B1 (https=)
JP (2) JP4707234B2 (https=)
AT (2) ATE318613T1 (https=)
AU (1) AU3580800A (https=)
CA (1) CA2318536C (https=)
DE (1) DE69930166T2 (https=)
DK (1) DK1049488T3 (https=)
ES (2) ES2379801T3 (https=)
WO (1) WO2000033872A2 (https=)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002064161A2 (en) * 2001-01-26 2002-08-22 Mcw Research Foundation, Inc. Method and compositions for immunization with the pseudomonas v antigen
AU2007231760B2 (en) * 2001-01-26 2009-10-29 Mcw Research Foundation, Inc. Method and compositions for immunization with the pseudomonas V antigen
DE10294091D2 (de) * 2001-09-13 2004-08-05 Hannover Med Hochschule Phänotyp bestimmende Virulenzgene von Pseudomonas aeruginosa zur Kolonisation und Persistenz in Mensch, Tier und Pflanze, Verwendungen der Gene und zugehörigen Proteine
AU2003226441A1 (en) * 2002-01-11 2003-07-24 Cornell Research Foundation, Inc. Methods of identifying putative effector proteins
EP1528935B1 (en) 2002-08-13 2012-03-21 Haptogen Ltd Methods for the treatment of an infectious bacterial disease with an anti-lactone or lactone derived signal molecules antibody
EP1761561B1 (en) * 2004-01-20 2015-08-26 KaloBios Pharmaceuticals, Inc. Antibody specificity transfer using minimal essential binding determinants
GB0407008D0 (en) 2004-03-27 2004-04-28 Haptogen Ltd Methods for inducing rapid cell death (autolysis) in infectious bacteria
GB0410958D0 (en) 2004-05-15 2004-06-16 Haptogen Ltd Methods for reducing biofilm formation in infectious bacteria
WO2007049770A1 (ja) 2005-10-28 2007-05-03 Meiji Seika Kaisha, Ltd. 緑膿菌の外膜タンパク質pa5158
CN101454446A (zh) 2006-03-30 2009-06-10 明治制果株式会社 绿脓杆菌的外膜蛋白pa0427
WO2009005040A1 (ja) * 2007-06-29 2009-01-08 Meiji Seika Kaisha Ltd. 緑膿菌の外膜タンパク質pa4710
BRPI0819598A2 (pt) 2007-11-30 2017-05-09 Kalobios Pharmaceuticals Inc anticorpos para o antígeno pcrv da pseudomonas aeruginosa
EP2236515A4 (en) * 2007-12-25 2012-10-31 Meiji Seika Kaisha COMPONENT PROTEIN PA1698 FOR PSEUDOMONAS AERUGINOSA TYPE-III SECRETION SYSTEM
EA020544B1 (ru) * 2008-01-10 2014-12-30 Шионоги Энд Ко., Лтд. АНТИТЕЛА ПРОТИВ PcrV
CA2751433A1 (en) 2009-02-04 2010-08-12 Kalobios Pharmaceuticals, Inc. Combination antibiotic and antibody therapy for the treatment of pseudomonas aeruginosa infection
SG174225A1 (en) 2009-03-11 2011-10-28 Shionogi & Co Humanized pcrv antibody having anti-pseudomonal activity
WO2011087799A1 (en) * 2009-12-22 2011-07-21 Kalobios Pharmaceuticals, Inc. A method of treating a staphylococcus infection in a patient having a low-level pathogenic pseudomonas aeruginosa infection
KR20140064768A (ko) * 2011-07-01 2014-05-28 더 트러스티스 오브 더 유니버시티 오브 펜실바니아 항-프로퍼딘 항체 및 그의 용도
HRP20201370T1 (hr) 2011-11-07 2020-11-27 Medimmune Limited Kombinacijske terapije koje koriste anti-pseudomonas psl i pcrv vezujuće molekule
CA2887050A1 (en) 2012-10-04 2014-04-10 Novelmed Therapeutics, Inc. Alternative pathway specific antibodies for treating hemolytic diseases
CN110028559B (zh) * 2019-04-15 2022-06-10 中国人民解放军陆军军医大学 一种铜绿假单胞菌疫苗重组蛋白及其编码基因和它们的应用
US20220378902A1 (en) * 2019-08-22 2022-12-01 Sichuan University Bacterial membrane vesicles, and separation and preparation system and method therefor
US20230071019A1 (en) * 2019-12-04 2023-03-09 The Research Foundation For The State University Of New York Compositions and methods for reducing off-target toxicity of antibody drug conjugates

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3178014B2 (ja) * 1991-07-05 2001-06-18 東ソー株式会社 Rnaの測定方法
US5599665A (en) * 1993-12-21 1997-02-04 Mcw Research Foundation Pseudomonas aeruginosa nucleic acids encoding exoenzyme S activity and use thereof in detecting pseudomonas aeruginosa infection

Also Published As

Publication number Publication date
ES2255329T3 (es) 2006-06-16
EP1666058A3 (en) 2008-03-12
DE69930166D1 (de) 2006-04-27
CA2318536C (en) 2009-11-17
US6827935B2 (en) 2004-12-07
AU3580800A (en) 2000-06-26
JP2002531522A (ja) 2002-09-24
CA2318536A1 (en) 2000-06-15
JP2011068672A (ja) 2011-04-07
EP1049488A1 (en) 2000-11-08
WO2000033872A3 (en) 2000-10-19
ATE539349T1 (de) 2012-01-15
ATE318613T1 (de) 2006-03-15
WO2000033872A2 (en) 2000-06-15
EP1666058A2 (en) 2006-06-07
US6309651B1 (en) 2001-10-30
EP1666058B1 (en) 2011-12-28
DE69930166T2 (de) 2006-12-14
EP1049488B1 (en) 2006-03-01
ES2379801T3 (es) 2012-05-03
US20040208888A1 (en) 2004-10-21
DK1049488T3 (da) 2006-06-26
WO2000033872A9 (en) 2000-12-14

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