WO2009005040A1 - 緑膿菌の外膜タンパク質pa4710 - Google Patents

緑膿菌の外膜タンパク質pa4710 Download PDF

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Publication number
WO2009005040A1
WO2009005040A1 PCT/JP2008/061867 JP2008061867W WO2009005040A1 WO 2009005040 A1 WO2009005040 A1 WO 2009005040A1 JP 2008061867 W JP2008061867 W JP 2008061867W WO 2009005040 A1 WO2009005040 A1 WO 2009005040A1
Authority
WO
WIPO (PCT)
Prior art keywords
pseudomonas aeruginosa
antigen
protein
peptide
outer membrane
Prior art date
Application number
PCT/JP2008/061867
Other languages
English (en)
French (fr)
Inventor
Jiro Tanaka
Hiroshi Nagaso
Masashi Kumagai
Keiko Otsuka
Hirotomo Akabane
Takahisa Suzuki
Original Assignee
Meiji Seika Kaisha Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Meiji Seika Kaisha Ltd. filed Critical Meiji Seika Kaisha Ltd.
Priority to JP2009521627A priority Critical patent/JPWO2009005040A1/ja
Priority to AU2008272087A priority patent/AU2008272087B2/en
Priority to CN2008800225648A priority patent/CN101878302A/zh
Priority to EP08777718A priority patent/EP2175017A4/en
Priority to US12/666,805 priority patent/US20100330100A1/en
Priority to CA002691626A priority patent/CA2691626A1/en
Publication of WO2009005040A1 publication Critical patent/WO2009005040A1/ja

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
    • C07K16/1214—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Pseudomonadaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/104—Pseudomonadales, e.g. Pseudomonas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/21—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pseudomonadaceae (F)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/44—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from protozoa
    • G01N2333/445—Plasmodium

Abstract

　緑膿菌感染を実質的に予防あるいは治療する能力を有し、緑膿菌感染患者由来の臨床分離株の多様性に対応できるワクチン組成物として使用可能なタンパク質抗原またはペプチド抗原、また、当該抗原に対する抗体を提供することを課題とする。本発明は、緑膿菌に関連する疾患の診断、予防、または治療に用いられるタンパク質抗原またはペプチド抗原およびこれらに対する抗体を提供する。本発明によれば、緑膿菌に関連する疾患の診断、予防、または治療に用いられる、緑膿菌の外膜タンパク質PA4710由来のタンパク質またはペプチドおよびこれらに対する抗体が提供される。  
PCT/JP2008/061867 2007-06-29 2008-06-30 緑膿菌の外膜タンパク質pa4710 WO2009005040A1 (ja)

Priority Applications (6)

Application Number Priority Date Filing Date Title
JP2009521627A JPWO2009005040A1 (ja) 2007-06-29 2008-06-30 緑膿菌の外膜タンパク質ｐａ４７１０
AU2008272087A AU2008272087B2 (en) 2007-06-29 2008-06-30 Pseudomonas aeruginosa outer membrane protein PA4710
CN2008800225648A CN101878302A (zh) 2007-06-29 2008-06-30 绿脓杆菌的外膜蛋白质pa4710
EP08777718A EP2175017A4 (en) 2007-06-29 2008-06-30 PROTEIN PA4710 THE OUTER MEMBRANE OF PSEUDOMONAS AERUGINOSA
US12/666,805 US20100330100A1 (en) 2007-06-29 2008-06-30 Pseudomonas aeruginosa-outer membrane protein pa4710
CA002691626A CA2691626A1 (en) 2007-06-29 2008-06-30 Pseudomonas aeruginosa-outer membrane protein pa4710

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007171680 2007-06-29
JP2007-171680 2007-06-29

Publications (1)

Publication Number Publication Date
WO2009005040A1 true WO2009005040A1 (ja) 2009-01-08

Family

ID=40226084

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/061867 WO2009005040A1 (ja) 2007-06-29 2008-06-30 緑膿菌の外膜タンパク質pa4710

Country Status (9)

Country Link
US (1) US20100330100A1 (ja)
EP (1) EP2175017A4 (ja)
JP (1) JPWO2009005040A1 (ja)
KR (1) KR20100028558A (ja)
CN (1) CN101878302A (ja)
AU (1) AU2008272087B2 (ja)
CA (1) CA2691626A1 (ja)
SG (1) SG182975A1 (ja)
WO (1) WO2009005040A1 (ja)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009088032A1 (ja) * 2008-01-10 2009-07-16 Shionogi & Co., Ltd. ＰｃｒＶに対する抗体
WO2011005587A1 (en) * 2009-06-24 2011-01-13 University Of Dubuque Vaccine compositions and methods of use to protect against infectious disease
US9085611B2 (en) 2009-03-11 2015-07-21 Shionogi & Co., Ltd. Humanized PcrV antibody having anti-pseudomonal activity
EP3345617A1 (en) 2012-11-30 2018-07-11 GlaxoSmithKline Biologicals S.A. Pseudomonas antigens and antigen combinations

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090155279A1 (en) * 2005-10-28 2009-06-18 Jiro Tanaka Pseudomonas Aeruginosa Outer Membrane Protein PA5158
CN105424929B (zh) * 2015-11-24 2017-08-08 四川夹金山逢春养殖科技有限公司 一种铜绿假单胞菌抗体检测试剂盒及检测方法
CN109486736B (zh) * 2018-11-16 2022-05-10 重庆艾力彼生物科技有限公司 铜绿假单胞菌基因工程疫苗候选抗原pa5505的纯化方法
CN111088269B (zh) * 2019-12-17 2020-11-20 中国科学院深圳先进技术研究院 OprJ-N-M融合基因及其融合蛋白、融合蛋白制备方法以及用途

Citations (3)

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Publication number Priority date Publication date Assignee Title
WO2002083843A2 (en) * 2001-04-10 2002-10-24 D-Squared Biotechnologies, Inc. Outer membrane associated polypeptides
WO2003006672A2 (en) * 2001-07-10 2003-01-23 D-Squared Biotechnologies, Inc. Antimicrobial nucleic acid antibodies, and materials and methods for making and using same
US6551795B1 (en) * 1998-02-18 2003-04-22 Genome Therapeutics Corporation Nucleic acid and amino acid sequences relating to pseudomonas aeruginosa for diagnostics and therapeutics

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US4450150A (en) * 1973-05-17 1984-05-22 Arthur D. Little, Inc. Biodegradable, implantable drug delivery depots, and method for preparing and using the same
GB8308235D0 (en) * 1983-03-25 1983-05-05 Celltech Ltd Polypeptides
EP0150184A1 (fr) * 1983-07-01 1985-08-07 Battelle Memorial Institute Polypeptide biodegradable et son utilisation pour le relargage progressif de medicaments
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WO2002083843A2 (en) * 2001-04-10 2002-10-24 D-Squared Biotechnologies, Inc. Outer membrane associated polypeptides
WO2003006672A2 (en) * 2001-07-10 2003-01-23 D-Squared Biotechnologies, Inc. Antimicrobial nucleic acid antibodies, and materials and methods for making and using same

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009088032A1 (ja) * 2008-01-10 2009-07-16 Shionogi & Co., Ltd. ＰｃｒＶに対する抗体
EP2599792A1 (en) * 2008-01-10 2013-06-05 Shionogi&Co., Ltd. Antibody directed against PcrV
US9085611B2 (en) 2009-03-11 2015-07-21 Shionogi & Co., Ltd. Humanized PcrV antibody having anti-pseudomonal activity
WO2011005587A1 (en) * 2009-06-24 2011-01-13 University Of Dubuque Vaccine compositions and methods of use to protect against infectious disease
US8647640B2 (en) 2009-06-24 2014-02-11 Richard E. COWART Vaccine compositions and methods of use to protect against infectious disease
EP3345617A1 (en) 2012-11-30 2018-07-11 GlaxoSmithKline Biologicals S.A. Pseudomonas antigens and antigen combinations

Also Published As

Publication number Publication date
KR20100028558A (ko) 2010-03-12
EP2175017A4 (en) 2010-10-27
CN101878302A (zh) 2010-11-03
CA2691626A1 (en) 2009-01-08
JPWO2009005040A1 (ja) 2010-08-26
SG182975A1 (en) 2012-08-30
AU2008272087A1 (en) 2009-01-08
AU2008272087B2 (en) 2013-06-13
US20100330100A1 (en) 2010-12-30
EP2175017A1 (en) 2010-04-14

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