ATE318613T1 - Verfahren und zusammensetzungen für impfung mit dem pseudomonas aeruginosa v-antigen - Google Patents

Verfahren und zusammensetzungen für impfung mit dem pseudomonas aeruginosa v-antigen

Info

Publication number
ATE318613T1
ATE318613T1 AT99971223T AT99971223T ATE318613T1 AT E318613 T1 ATE318613 T1 AT E318613T1 AT 99971223 T AT99971223 T AT 99971223T AT 99971223 T AT99971223 T AT 99971223T AT E318613 T1 ATE318613 T1 AT E318613T1
Authority
AT
Austria
Prior art keywords
pseudomonas aeruginosa
antigen
vaccination
compositions
methods
Prior art date
Application number
AT99971223T
Other languages
English (en)
Inventor
Dara W Frank
Timothy L Yahr
Teiji Sawa
Jeanine Wiener-Kronish
Original Assignee
Mcw Res Found Inc
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mcw Res Found Inc, Univ California filed Critical Mcw Res Found Inc
Application granted granted Critical
Publication of ATE318613T1 publication Critical patent/ATE318613T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/104—Pseudomonadales, e.g. Pseudomonas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/21—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pseudomonadaceae (F)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/21—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Pseudomonadaceae (F)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00—Immunoassays for the detection of microorganisms
    • G01N2469/20—Detection of antibodies in sample from host which are directed against antigens from microorganisms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • General Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Food Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
AT99971223T 1998-11-25 1999-11-23 Verfahren und zusammensetzungen für impfung mit dem pseudomonas aeruginosa v-antigen ATE318613T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10995298P 1998-11-25 1998-11-25
US12679499P 1999-03-30 1999-03-30

Publications (1)

Publication Number Publication Date
ATE318613T1 true ATE318613T1 (de) 2006-03-15

Family

ID=26807543

Family Applications (2)

Application Number Title Priority Date Filing Date
AT06000111T ATE539349T1 (de) 1998-11-25 1999-11-23 Verfahren zur diagnose einer pseudomonas aeruginosa infektion
AT99971223T ATE318613T1 (de) 1998-11-25 1999-11-23 Verfahren und zusammensetzungen für impfung mit dem pseudomonas aeruginosa v-antigen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT06000111T ATE539349T1 (de) 1998-11-25 1999-11-23 Verfahren zur diagnose einer pseudomonas aeruginosa infektion

Country Status (10)

Country Link
US (2) US6309651B1 (de)
EP (2) EP1049488B1 (de)
JP (2) JP4707234B2 (de)
AT (2) ATE539349T1 (de)
AU (1) AU3580800A (de)
CA (1) CA2318536C (de)
DE (1) DE69930166T2 (de)
DK (1) DK1049488T3 (de)
ES (2) ES2255329T3 (de)
WO (1) WO2000033872A2 (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2007231760B2 (en) * 2001-01-26 2009-10-29 Mcw Research Foundation, Inc. Method and compositions for immunization with the pseudomonas V antigen
DE60216564T2 (de) * 2001-01-26 2007-10-11 MCW Research Foundation, Inc., Milwaukee Verfahren und zusammensetzungen für immunisierung mit dem pseudomonas antigen
US20060008477A1 (en) * 2001-09-13 2006-01-12 Tuemmler Burkhard Phenotype-determining virulence genes of pseudomonas aeruginosa for colonization and persistence in human beings, animals and plants, uses of said gene and associated proteins
WO2003058205A2 (en) * 2002-01-11 2003-07-17 Cornell Research Foundation, Inc. Methods of identifying putative effector proteins
EP1528935B1 (de) 2002-08-13 2012-03-21 Haptogen Ltd Verfahren zur behandlung einer bakteriellen infektionskrankheit mittels antikörpern gegen laktone oder gegen von laktonen abgeleiteten signalmolekülen
CA2553692C (en) * 2004-01-20 2014-10-07 Kalobios, Inc. Antibody specificity transfer using minimal essential binding determinants
GB0407008D0 (en) 2004-03-27 2004-04-28 Haptogen Ltd Methods for inducing rapid cell death (autolysis) in infectious bacteria
GB0410958D0 (en) 2004-05-15 2004-06-16 Haptogen Ltd Methods for reducing biofilm formation in infectious bacteria
JPWO2007049770A1 (ja) 2005-10-28 2009-04-30 明治製菓株式会社 緑膿菌の外膜タンパク質ｐａ５１５８
CA2645904A1 (en) 2006-03-30 2007-10-11 Meiji Seika Kaisha, Ltd. Pseudomonas aeruginosa outer membrane protein pa0427
WO2009005040A1 (ja) * 2007-06-29 2009-01-08 Meiji Seika Kaisha Ltd. 緑膿菌の外膜タンパク質pa4710
JP5781765B2 (ja) * 2007-11-30 2015-09-24 カロバイオス ファーマシューティカルズ インコーポレイティッド シュードモナス・エルギノーサ（ＰｓｅｕｄｏｍｏｎａｓＡｅｒｕｇｉｎｏｓａ）のＰｃｒＶ抗原に対する抗体
WO2009081955A1 (ja) 2007-12-25 2009-07-02 Meiji Seika Kaisha, Ltd. 緑膿菌のiii型分泌装置構成タンパク質pa1698
CN102137870B (zh) * 2008-01-10 2014-09-03 盐野义制药株式会社 抗PcrV抗体
JP2012516897A (ja) 2009-02-04 2012-07-26 カロバイオス ファーマシューティカルズ インコーポレイティッド シュードモナス・エルギノーサ（ＰｓｅｕｄｏｍｏｎａｓＡｅｒｕｇｉｎｏｓａ）感染の治療のための抗生物質と抗体療法との組み合わせ
CN104119437A (zh) 2009-03-11 2014-10-29 盐野义制药株式会社 具有抗绿脓杆菌作用的人源化PcrV抗体
CA2784033A1 (en) * 2009-12-22 2011-07-21 Kalobios Pharmaceuticals, Inc. A method of treating a staphylococcus infection in a patient having a low-level pathogenic pseudomonas aeruginosa infection
JP6293659B2 (ja) * 2011-07-01 2018-03-14 ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア 抗プロペルジン抗体およびその使用
LT2776065T (lt) 2011-11-07 2020-10-12 Medimmune Limited Kombinuotos terapijos, panaudojančios prieš pseudomonas psl ir pcrv nukreiptas, juos surišančias molekules
JP2015532303A (ja) 2012-10-04 2015-11-09 ノベルメド セラピューティクス，インコーポレーテッド 溶血性疾患を治療するための補体第２経路特異的抗体
CN110028559B (zh) * 2019-04-15 2022-06-10 中国人民解放军陆军军医大学 一种铜绿假单胞菌疫苗重组蛋白及其编码基因和它们的应用
US20220378902A1 (en) * 2019-08-22 2022-12-01 Sichuan University Bacterial membrane vesicles, and separation and preparation system and method therefor

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3178014B2 (ja) * 1991-07-05 2001-06-18 東ソー株式会社 Ｒｎａの測定方法
US5599665A (en) * 1993-12-21 1997-02-04 Mcw Research Foundation Pseudomonas aeruginosa nucleic acids encoding exoenzyme S activity and use thereof in detecting pseudomonas aeruginosa infection

Also Published As

Publication number Publication date
US6827935B2 (en) 2004-12-07
EP1666058B1 (de) 2011-12-28
ES2379801T3 (es) 2012-05-03
US20040208888A1 (en) 2004-10-21
DK1049488T3 (da) 2006-06-26
EP1666058A2 (de) 2006-06-07
DE69930166D1 (de) 2006-04-27
ATE539349T1 (de) 2012-01-15
DE69930166T2 (de) 2006-12-14
AU3580800A (en) 2000-06-26
ES2255329T3 (es) 2006-06-16
WO2000033872A2 (en) 2000-06-15
EP1049488A1 (de) 2000-11-08
WO2000033872A3 (en) 2000-10-19
WO2000033872A9 (en) 2000-12-14
CA2318536A1 (en) 2000-06-15
JP4707234B2 (ja) 2011-06-22
EP1049488B1 (de) 2006-03-01
JP2011068672A (ja) 2011-04-07
JP2002531522A (ja) 2002-09-24
CA2318536C (en) 2009-11-17
EP1666058A3 (de) 2008-03-12
US6309651B1 (en) 2001-10-30

Similar Documents

Publication Publication Date Title
ATE318613T1 (de) Verfahren und zusammensetzungen für impfung mit dem pseudomonas aeruginosa v-antigen
ATE347374T1 (de) Verfahren und zusammensetzungen für immunisierung mit dem pseudomonas antigen
DE3789874T2 (de) Thermometrisches verfahren für lebende organismen und gerät dazu.
DE69111959D1 (de) Verfahren und Gerät zur Dampfung von maschinenerregten Rauschen.
ES2063912T3 (es) Composiciones inmunogenicas frente a peptidos de gastrina.
DE69510336T2 (de) Verfahren zur diagnose von praeklampsie
FR2653282B1 (fr) Procede de correction numerique de non linearite d'une chaine d'emission, et dispositif de mise en óoeuvre de ce procede.
PT946873E (pt) Metodos para diagnostico da aspergilose broncopulmonar alergica
DE69022346T2 (de) MOS-Feldeffekttransistor und Verfahren zur Herstellung.
ATE325621T1 (de) Il-12 als adjuvanz für bordetella pertussis impfstoffe
DE59010919D1 (de) N- und O-substituierte Aminophenolderivate, Zwischenprodukte zu deren Herstellung, deren Verwendung als Hydrolasesubstrate, ein entsprechendes Bestimmungsverfahren und hierfür geeignetes diagnostisches Mittel
DE69723243D1 (de) Sterilisationsschutzmittel und verfahren zur sterilisation
ATE275268T1 (de) Verfahren zur diagnose von sjögren-syndrom
DE3484681D1 (de) Verfahren zur aussetzung eines bakteriellen antigens und dasselbe verwendendes diagnostisches testverfahren.
ATE210460T1 (de) Zusammensetzungen, welche adp-ribosyltransferase- aktivität aufweisen und methoden für ihre herstellung und die verwendung derselben
DE69013425T2 (de) Pseudomonasmutant, yzh-Stamm und Verfahren zur Herstellung der 851yzh-Nährlösung mittels dieses Stammes.
ATE206138T1 (de) Helicobacter pylori antigen
DE58902675D1 (de) Verfahren zur steigerung des anteils an siliciumtetrachlorid.
ATE377944T1 (de) Methode für die behandlung einer hepatitisvirusinfektion
ES2179867T3 (es) Entrecruzamientos de piridinolina como marcadores de actividad de enfermedad periodontal o peri-implante.
SE8901188D0 (sv) A novel diagnostic method
DE59005556D1 (de) Verfahren und einrichtung zur überprüfung des abschalt-drehmomentes eines stellantriebes.
ATE100265T1 (de) Einrichtung zur einstellung eines hoergeraetes durch den patienten , verfahren und testeinrichtung fuer dieses hoergeraet.
DE3852489T2 (de) Gerät zur Kalibrierung eines optisches Katheters und Verfahren.
UA30274A (uk) Спосіб діагностики носійства токсогенного штаму дифтерійної палички

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1049488

Country of ref document: EP

REN Ceased due to non-payment of the annual fee