DK1049488T3 - Fremgangsmåde og præparat til immunisering med Pseudomonas aeruginosa-V-antigenet - Google Patents

Fremgangsmåde og præparat til immunisering med Pseudomonas aeruginosa-V-antigenet

Info

Publication number
DK1049488T3
DK1049488T3 DK99971223T DK99971223T DK1049488T3 DK 1049488 T3 DK1049488 T3 DK 1049488T3 DK 99971223 T DK99971223 T DK 99971223T DK 99971223 T DK99971223 T DK 99971223T DK 1049488 T3 DK1049488 T3 DK 1049488T3
Authority
DK
Denmark
Prior art keywords
pseudomonas aeruginosa
antigen
immunization
preparation
moderating
Prior art date
Application number
DK99971223T
Other languages
English (en)
Inventor
Dara W Frank
Timothy L Yahr
Jeanine Wiener-Kronish
Teiji Sawa
Original Assignee
Mcw Res Found Inc
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mcw Res Found Inc, Univ California filed Critical Mcw Res Found Inc
Application granted granted Critical
Publication of DK1049488T3 publication Critical patent/DK1049488T3/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/104Pseudomonadales, e.g. Pseudomonas
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/21Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pseudomonadaceae (F)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911Bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/21Assays involving biological materials from specific organisms or of a specific nature from bacteria from Pseudomonadaceae (F)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00Immunoassays for the detection of microorganisms
    • G01N2469/20Detection of antibodies in sample from host which are directed against antigens from microorganisms

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Epidemiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • General Physics & Mathematics (AREA)
  • Virology (AREA)
DK99971223T 1998-11-25 1999-11-23 Fremgangsmåde og præparat til immunisering med Pseudomonas aeruginosa-V-antigenet DK1049488T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10995298P 1998-11-25 1998-11-25
US12679499P 1999-03-30 1999-03-30

Publications (1)

Publication Number Publication Date
DK1049488T3 true DK1049488T3 (da) 2006-06-26

Family

ID=26807543

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99971223T DK1049488T3 (da) 1998-11-25 1999-11-23 Fremgangsmåde og præparat til immunisering med Pseudomonas aeruginosa-V-antigenet

Country Status (10)

Country Link
US (2) US6309651B1 (da)
EP (2) EP1666058B1 (da)
JP (2) JP4707234B2 (da)
AT (2) ATE318613T1 (da)
AU (1) AU3580800A (da)
CA (1) CA2318536C (da)
DE (1) DE69930166T2 (da)
DK (1) DK1049488T3 (da)
ES (2) ES2379801T3 (da)
WO (1) WO2000033872A2 (da)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2007231760B2 (en) * 2001-01-26 2009-10-29 Mcw Research Foundation, Inc. Method and compositions for immunization with the pseudomonas V antigen
ATE347374T1 (de) * 2001-01-26 2006-12-15 Mcw Res Found Inc Verfahren und zusammensetzungen für immunisierung mit dem pseudomonas antigen
WO2003022881A2 (de) * 2001-09-13 2003-03-20 Medizinische Hochschule Hannover Phänotyp bestimmende virulenzgene von pseudomonas aeruginosa zur kolonisation und persistenz in mensch, tier und pflanze, verwendungen der gene und zugehörigen proteine
WO2003058205A2 (en) * 2002-01-11 2003-07-17 Cornell Research Foundation, Inc. Methods of identifying putative effector proteins
US7812134B2 (en) 2002-08-13 2010-10-12 Haptogen Ltd. Methods for the treatment of an infectious bacterial disease with an anti-lactone or lactone derived signal molecules antibody
EP1761561B1 (en) * 2004-01-20 2015-08-26 KaloBios Pharmaceuticals, Inc. Antibody specificity transfer using minimal essential binding determinants
GB0407008D0 (en) 2004-03-27 2004-04-28 Haptogen Ltd Methods for inducing rapid cell death (autolysis) in infectious bacteria
GB0410958D0 (en) 2004-05-15 2004-06-16 Haptogen Ltd Methods for reducing biofilm formation in infectious bacteria
CN101351221A (zh) 2005-10-28 2009-01-21 明治制果株式会社 绿脓杆菌的外膜蛋白pa5158
SG170804A1 (en) 2006-03-30 2011-05-30 Meiji Seika Kaisha Pseudomonas aeruginosa outer membrane protein pa0427
JPWO2009005040A1 (ja) * 2007-06-29 2010-08-26 明治製菓株式会社 緑膿菌の外膜タンパク質pa4710
EP2220117A2 (en) * 2007-11-30 2010-08-25 Kalobios Pharmaceuticals, Inc. Antibodies to the pcrv antigen of pseudomonas aeruginosa
AU2008342152B2 (en) 2007-12-25 2013-06-27 Meiji Seika Pharma Co., Ltd. Component protein PA1698 for type-III secretion system of Pseudomonas aeruginosa
EP2248826B1 (en) * 2008-01-10 2013-06-12 Shionogi&Co., Ltd. Antibody directed against pcrv
EP2393515A1 (en) 2009-02-04 2011-12-14 Kalobios Pharmaceuticals, Inc. Combination antibiotic and antibody therapy for the treatment of pseudomonas aeruginosa infection
BRPI1008977A2 (pt) 2009-03-11 2016-10-04 Shionogi & Co anticorpo para pcrv humanizado que possui atividade anti-pseudomonal
JP2013515079A (ja) * 2009-12-22 2013-05-02 カロバイオス ファーマシューティカルズ インコーポレイティッド 低レベルの病原性シュードモナス・エルギノーサ(Pseudomonasaeruginosa)感染症を有する患者のスタフィロコッカス(Staphylococcus)感染症を治療する方法
AU2012279288B2 (en) * 2011-07-01 2017-07-20 The Trustees Of The University Of Pennsylvania Anti-properdin antibodies and uses thereof
KR102184343B1 (ko) 2011-11-07 2020-11-30 메디뮨 엘엘씨 항슈도모나스 psl 및 pcrv 결합 분자를 이용한 병용 요법
US9926366B2 (en) 2012-10-04 2018-03-27 Novelmed Therapeutics, Inc. Methods of treating a hemolytic disorder comprising administering anti-properdin antibodies
CN110028559B (zh) * 2019-04-15 2022-06-10 中国人民解放军陆军军医大学 一种铜绿假单胞菌疫苗重组蛋白及其编码基因和它们的应用
WO2021031270A1 (zh) * 2019-08-22 2021-02-25 四川大学 细菌膜囊泡及其分离制备系统和方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3178014B2 (ja) * 1991-07-05 2001-06-18 東ソー株式会社 Rnaの測定方法
US5599665A (en) * 1993-12-21 1997-02-04 Mcw Research Foundation Pseudomonas aeruginosa nucleic acids encoding exoenzyme S activity and use thereof in detecting pseudomonas aeruginosa infection

Also Published As

Publication number Publication date
US20040208888A1 (en) 2004-10-21
JP2002531522A (ja) 2002-09-24
AU3580800A (en) 2000-06-26
JP2011068672A (ja) 2011-04-07
EP1666058A3 (en) 2008-03-12
WO2000033872A9 (en) 2000-12-14
JP4707234B2 (ja) 2011-06-22
CA2318536A1 (en) 2000-06-15
US6309651B1 (en) 2001-10-30
ES2255329T3 (es) 2006-06-16
US6827935B2 (en) 2004-12-07
EP1049488B1 (en) 2006-03-01
WO2000033872A2 (en) 2000-06-15
ATE318613T1 (de) 2006-03-15
EP1666058A2 (en) 2006-06-07
DE69930166D1 (de) 2006-04-27
EP1049488A1 (en) 2000-11-08
CA2318536C (en) 2009-11-17
WO2000033872A3 (en) 2000-10-19
EP1666058B1 (en) 2011-12-28
DE69930166T2 (de) 2006-12-14
ES2379801T3 (es) 2012-05-03
ATE539349T1 (de) 2012-01-15

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