DE69928278T2 - Therapeutisches antimykotisches Nagelpräparat - Google Patents
Therapeutisches antimykotisches Nagelpräparat Download PDFInfo
- Publication number
- DE69928278T2 DE69928278T2 DE69928278T DE69928278T DE69928278T2 DE 69928278 T2 DE69928278 T2 DE 69928278T2 DE 69928278 T DE69928278 T DE 69928278T DE 69928278 T DE69928278 T DE 69928278T DE 69928278 T2 DE69928278 T2 DE 69928278T2
- Authority
- DE
- Germany
- Prior art keywords
- dmso
- solution
- miconazole
- ibuprofen
- polyglycol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Emergency Medicine (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/193,073 US6159977A (en) | 1998-11-16 | 1998-11-16 | Therapeutic anti-fungal nail preparation |
PCT/US1999/027053 WO2000028821A1 (en) | 1998-11-16 | 1999-11-15 | Therapeutic anti-fungal nail preparation |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69928278D1 DE69928278D1 (de) | 2005-12-15 |
DE69928278T2 true DE69928278T2 (de) | 2006-06-14 |
Family
ID=22712177
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69928278T Expired - Lifetime DE69928278T2 (de) | 1998-11-16 | 1999-11-15 | Therapeutisches antimykotisches Nagelpräparat |
Country Status (12)
Country | Link |
---|---|
US (2) | US6159977A (de) |
EP (1) | EP1130964B1 (de) |
JP (1) | JP2003535020A (de) |
CN (1) | CN1181738C (de) |
AT (1) | ATE309032T1 (de) |
AU (1) | AU771851B2 (de) |
BR (1) | BR9915394A (de) |
CA (1) | CA2351536C (de) |
DE (1) | DE69928278T2 (de) |
IL (1) | IL143156A (de) |
MX (1) | MXPA01004908A (de) |
WO (1) | WO2000028821A1 (de) |
Families Citing this family (80)
Publication number | Priority date | Publication date | Assignee | Title |
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US6605751B1 (en) | 1997-11-14 | 2003-08-12 | Acrymed | Silver-containing compositions, devices and methods for making |
US7655252B2 (en) | 1999-04-28 | 2010-02-02 | The Regents Of The University Of Michigan | Antimicrobial nanoemulsion compositions and methods |
US6635676B2 (en) * | 1999-04-28 | 2003-10-21 | Regents Of The University Of Michigan | Non-toxic antimicrobial compositions and methods of use |
US6541517B1 (en) * | 1999-09-03 | 2003-04-01 | Donald M. Murphy | Treatment of skin disorders |
DE60028415T2 (de) | 1999-12-30 | 2007-06-06 | Acrymed, Portland | Methode und zusammensetzungen für verbesserte abgabevorrichtungen |
US8257688B2 (en) * | 2000-03-27 | 2012-09-04 | Taro Pharmaceuticals Industries | Controlled delivery system of antifungal and keratolytic agents for local treatment of fungal infections of the nail and surrounding tissues |
US7074392B1 (en) | 2000-03-27 | 2006-07-11 | Taro Pharmaceutical Industries Limited | Controllled delivery system of antifungal and keratolytic agents for local treatment of fungal infections |
US6878365B2 (en) * | 2001-03-10 | 2005-04-12 | James Edward Brehove | Topical application for treating toenail fungus |
GB0108082D0 (en) * | 2001-03-30 | 2001-05-23 | Novartis Consumer Health Sa | Topical composition |
JP2010209109A (ja) * | 2001-06-25 | 2010-09-24 | Regents Of The Univ Of Michigan | 抗微生物ナノエマルジョンの組成物および方法 |
AU2002364893A1 (en) * | 2001-10-22 | 2003-06-17 | University Of Mississippi | Delivery of medicaments to the nail |
US20030144625A1 (en) * | 2002-01-28 | 2003-07-31 | Garry Sherman | Method and apparatus for the treatment of infections of the nail matrix and nail plate |
US8486426B2 (en) | 2002-07-29 | 2013-07-16 | Kimberly-Clark Worldwide, Inc. | Methods and compositions for treatment of dermal conditions |
US6921529B2 (en) * | 2002-07-29 | 2005-07-26 | Joseph C. Maley | Treatment modality and method for fungal nail infection |
US7374772B2 (en) * | 2002-11-07 | 2008-05-20 | Bommarito Alexander A | Topical antifungal treatment |
US20040126343A1 (en) * | 2002-12-26 | 2004-07-01 | Garshowitz Solomon David | Nail drug delivery |
US7311928B2 (en) * | 2003-12-09 | 2007-12-25 | Briant Burke | Topical compositions containing tea tree oil for treatment of viral lesions |
AU2005280443B2 (en) | 2004-07-30 | 2011-02-03 | Avent, Inc. | Antimicrobial silver compositions |
CN101010004B (zh) | 2004-07-30 | 2012-10-03 | 金伯利-克拉克环球有限公司 | 抗微生物的装置和组合物 |
US8361553B2 (en) | 2004-07-30 | 2013-01-29 | Kimberly-Clark Worldwide, Inc. | Methods and compositions for metal nanoparticle treated surfaces |
WO2006034249A2 (en) | 2004-09-20 | 2006-03-30 | Acrymed, Inc. | Antimicrobial amorphous compositions |
US20060078580A1 (en) | 2004-10-08 | 2006-04-13 | Mediquest Therapeutics, Inc. | Organo-gel formulations for therapeutic applications |
US7740875B2 (en) * | 2004-10-08 | 2010-06-22 | Mediquest Therapeutics, Inc. | Organo-gel formulations for therapeutic applications |
US20060153786A1 (en) * | 2004-12-10 | 2006-07-13 | Talima Therapeutics, Inc. | Compositions and methods for treating conditions of the nail unit |
US20060275230A1 (en) | 2004-12-10 | 2006-12-07 | Frank Kochinke | Compositions and methods for treating conditions of the nail unit |
US20060251593A1 (en) * | 2005-04-07 | 2006-11-09 | Work By Docs, Inc. | Colored nail enamel treatment |
JP2010279384A (ja) * | 2005-08-31 | 2010-12-16 | Pola Pharma Inc | 抗真菌剤 |
US20090215888A1 (en) * | 2006-03-02 | 2009-08-27 | Singh Jagat | Topical nail formulation |
EP2015722B1 (de) | 2006-04-28 | 2016-11-16 | Avent, Inc. | Antimikrobielle verbände |
CN101484162A (zh) | 2006-05-12 | 2009-07-15 | 药品控制研究及咨询有限责任公司 | 包含抗真菌试剂的组合制剂的用途 |
US8747872B2 (en) | 2007-05-02 | 2014-06-10 | The Regents Of The University Of Michigan | Nanoemulsion therapeutic compositions and methods of using the same |
US20110082118A1 (en) * | 2007-06-19 | 2011-04-07 | Bhiku Patel | Onychomycosis Treatment Delivery System |
US20110076261A1 (en) * | 2007-06-19 | 2011-03-31 | Bhiku Patel | Antifungal Drug Delivery System |
US20080317737A1 (en) * | 2007-06-19 | 2008-12-25 | Prugen, Inc. | Drug combination for the treatment of skin disorders |
US20090175810A1 (en) | 2008-01-03 | 2009-07-09 | Gareth Winckle | Compositions and methods for treating diseases of the nail |
US9320921B2 (en) * | 2008-12-22 | 2016-04-26 | Karen C. Swenholt | Nail fungus treatment and composition |
WO2010057197A1 (en) | 2008-11-17 | 2010-05-20 | The Regents Of The University Of Michigan | Cancer vaccine compositions and methods of using the same |
US8193232B2 (en) * | 2009-02-13 | 2012-06-05 | Topica Pharmaceuticals, Inc. | Anti-fungal formulation |
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GB0907553D0 (en) | 2009-05-01 | 2009-06-10 | Insense Ltd | Treatment of human or animal body surface infection |
US20100292333A1 (en) * | 2009-05-15 | 2010-11-18 | bioCEPTA Corporation | Compositions suitable for the topical treatment of fungal infections of the skin and nails |
CN102869345B (zh) | 2010-03-17 | 2015-02-11 | 诺瓦利克有限责任公司 | 用于治疗眼内压增高的药物组合物 |
SI23311A (sl) * | 2010-03-19 | 2011-09-30 | Kemijski inštitut | Farmacevtska kombinacija acetilsalicilne kisline in protiglivne substance za uničevanje ali inhibicijo rasti in replikacije gliv |
ES2369101B2 (es) | 2010-05-07 | 2012-08-02 | Universidade De Santiago De Compostela | Sistema farmacéutico acuoso para la administración de fármacos en las uñas. |
EP2444063A1 (de) | 2010-10-20 | 2012-04-25 | Novaliq GmbH | Flüssige pharmazeutische Zusammensetzungen zur Abgabe von Wirkstoffen |
EP2462921A1 (de) | 2010-11-11 | 2012-06-13 | Novaliq GmbH | Flüssige pharmazeutische Zusammensetzungen zur Behandlung einer Erkrankung der Hinterseite des Auges |
WO2012126899A2 (en) * | 2011-03-18 | 2012-09-27 | Katholieke Universiteit Leuven Ku Leuven Research & Development | Inhibition and treatment of biofilms |
EP3348272B1 (de) * | 2011-05-11 | 2020-06-24 | Veloce BioPharma LLC | Zusammensetzungen zur verwendung in der behandlung von paronychie |
PL2714010T3 (pl) | 2011-05-25 | 2017-08-31 | Novaliq Gmbh | Kompozycja farmaceutyczna do miejscowego stosowania oparta na semifluorowanych alkanach |
WO2012160180A2 (en) | 2011-05-25 | 2012-11-29 | Novaliq Gmbh | Pharmaceutical composition for administration to nails |
AU2013211645B2 (en) | 2012-01-23 | 2017-06-15 | Novaliq Gmbh | Stabilised protein compositions based on semifluorinated alkanes |
US9750683B2 (en) | 2012-02-17 | 2017-09-05 | Veloce Biopharma, Llc | Antifungal compositions for the treatment of skin and nails |
CA2775393C (en) * | 2012-05-02 | 2014-04-29 | Samy Saad | Topical non-aqueous pharmaceutical formulations |
EP2895158B1 (de) | 2012-09-12 | 2019-11-20 | Novaliq GmbH | Zusammensetzungen mit mischungen aus semifluorierten alkanen |
EP3181119B1 (de) | 2012-09-12 | 2019-07-10 | Novaliq GmbH | Zusammensetzungen semifluorierter alkane zur verwendung in der behandlung von keratoconjunctivitis sicca |
US8697753B1 (en) | 2013-02-07 | 2014-04-15 | Polichem Sa | Method of treating onychomycosis |
RU2015143995A (ru) | 2013-03-14 | 2017-04-20 | Халлюкс, Инк. | Способ лечения инфекций, заболеваний или расстройств ногтевого ложа |
JP6503349B2 (ja) | 2013-07-23 | 2019-04-17 | ノバリック ゲーエムベーハー | 安定化された抗体組成物 |
GB2518826A (en) * | 2013-09-27 | 2015-04-08 | Thanasis Athanasiou | Composition |
EP2952208A1 (de) | 2014-06-04 | 2015-12-09 | Universidade de Santiago de Compostela | Hydroalkoholisches System zur Nagelbehandlung |
CN113368215A (zh) | 2014-10-21 | 2021-09-10 | 赫希玛有限公司 | 一种治疗方法 |
MX2017009450A (es) | 2015-01-20 | 2018-01-18 | Veloce Biopharma Llc | Composicion yodofora novedosa y metodos de uso. |
US11612560B2 (en) * | 2015-09-08 | 2023-03-28 | The University Of Toledo | Treatment of Raynaud's phenomenon by inhibition of transient receptor potential melastatin-8 (TRPM-8) |
PT3355990T (pt) | 2015-09-30 | 2019-09-11 | Novaliq Gmbh | Compostos semifluorados e as suas composições |
DE202016008739U1 (de) | 2015-09-30 | 2019-04-29 | Novaliq Gmbh | Semifluorierte Verbindungen |
KR102257916B1 (ko) | 2016-06-23 | 2021-05-28 | 노바리크 게엠베하 | 드롭 디스펜서를 포함하는 키트 |
US10258560B1 (en) | 2016-08-08 | 2019-04-16 | Marlinz Pharma, LLC | Composition for topical treatment of nail conditions |
US10543276B2 (en) | 2016-08-08 | 2020-01-28 | Marlinz Pharma, LLC | Topical compositions |
CN109890374A (zh) | 2016-09-22 | 2019-06-14 | 诺瓦利克有限责任公司 | 用于治疗睑缘炎的药物组合物 |
JP6869336B2 (ja) | 2016-09-23 | 2021-05-12 | ノバリック ゲーエムベーハー | シクロスポリンを含む眼科用組成物 |
JPWO2018117125A1 (ja) * | 2016-12-19 | 2019-08-08 | 富士フイルム株式会社 | 経皮製剤 |
WO2018160613A1 (en) * | 2017-02-28 | 2018-09-07 | Temple University-Of The Commonwealth System Of Higher Education | Novel econazole nitrate medical patch and methods of use thereof |
WO2018193093A1 (en) | 2017-04-21 | 2018-10-25 | Novaliq Gmbh | Iodine compositions |
CN110650734A (zh) | 2017-05-12 | 2020-01-03 | 诺瓦利克有限责任公司 | 治疗与隐形眼镜有关病症的包含半氟化烷烃的药物组合物 |
CN111372566A (zh) | 2017-09-27 | 2020-07-03 | 诺瓦利克有限责任公司 | 用于治疗眼部疾病的包含拉坦前列素的眼科用组合物 |
US11896559B2 (en) | 2017-10-04 | 2024-02-13 | Novaliq Gmbh | Opthalmic compositions comprising F6H8 |
WO2019166631A1 (en) | 2018-03-02 | 2019-09-06 | Novaliq Gmbh | Pharmaceutical compositions comprising nebivolol |
AU2019345929B2 (en) | 2018-09-27 | 2022-02-03 | Dermaliq Therapeutics, Inc. | Topical sunscreen formulation |
CN112823020A (zh) | 2018-10-12 | 2021-05-18 | 诺瓦利克有限责任公司 | 用于治疗干眼病的眼用组合物 |
CN110537545A (zh) * | 2019-09-12 | 2019-12-06 | 青岛农业大学 | 噻康唑在制备用于防治植物病原菌的杀菌剂中的应用 |
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JPH07506367A (ja) * | 1992-05-05 | 1995-07-13 | ザ、プロクター、エンド、ギャンブル、カンパニー | アクネ治療組成物 |
GB2275191B (en) * | 1993-02-10 | 1996-11-27 | Donald John Dear | Use of antifungal compounds in the treatment of skin disorders |
IL105600A (en) * | 1993-05-04 | 1999-12-31 | Allon Blank | Pharmaceutical and cosmetic compositions with increased rate of transdermal penetration and antioxidation protection against degradation containing derivatives of thioglycolic and mercaptopropionic acids some such novel compounds and their use |
DE4337945A1 (de) * | 1993-11-06 | 1995-05-11 | Labtec Gmbh | Pflaster zur Behandlung von Nagelmykosen |
IT1265001B1 (it) * | 1993-12-16 | 1996-10-17 | Zambon Spa | Composizione farmaceutica per uso topico contenente acido (s)-2-(4- isobutilfenil) propionico |
-
1998
- 1998-11-16 US US09/193,073 patent/US6159977A/en not_active Expired - Lifetime
-
1999
- 1999-11-15 CN CNB998147346A patent/CN1181738C/zh not_active Expired - Fee Related
- 1999-11-15 CA CA002351536A patent/CA2351536C/en not_active Expired - Fee Related
- 1999-11-15 MX MXPA01004908A patent/MXPA01004908A/es not_active IP Right Cessation
- 1999-11-15 JP JP2000581886A patent/JP2003535020A/ja active Pending
- 1999-11-15 IL IL14315699A patent/IL143156A/xx not_active IP Right Cessation
- 1999-11-15 BR BR9915394-7A patent/BR9915394A/pt not_active Application Discontinuation
- 1999-11-15 WO PCT/US1999/027053 patent/WO2000028821A1/en active IP Right Grant
- 1999-11-15 DE DE69928278T patent/DE69928278T2/de not_active Expired - Lifetime
- 1999-11-15 AU AU17257/00A patent/AU771851B2/en not_active Ceased
- 1999-11-15 EP EP99960362A patent/EP1130964B1/de not_active Expired - Lifetime
- 1999-11-15 AT AT99960362T patent/ATE309032T1/de not_active IP Right Cessation
-
2000
- 2000-08-17 US US09/640,439 patent/US6391879B1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
AU1725700A (en) | 2000-06-05 |
ATE309032T1 (de) | 2005-11-15 |
IL143156A (en) | 2005-11-20 |
EP1130964A4 (de) | 2002-06-19 |
EP1130964B1 (de) | 2005-11-09 |
MXPA01004908A (es) | 2003-03-10 |
BR9915394A (pt) | 2002-03-05 |
DE69928278D1 (de) | 2005-12-15 |
US6391879B1 (en) | 2002-05-21 |
US6159977A (en) | 2000-12-12 |
CA2351536C (en) | 2007-08-07 |
JP2003535020A (ja) | 2003-11-25 |
AU771851B2 (en) | 2004-04-01 |
IL143156A0 (en) | 2002-04-21 |
CN1359262A (zh) | 2002-07-17 |
WO2000028821A1 (en) | 2000-05-25 |
CN1181738C (zh) | 2004-12-29 |
EP1130964A1 (de) | 2001-09-12 |
CA2351536A1 (en) | 2000-05-25 |
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