IL143156A - Therapeutic anti-fungal nail preparation - Google Patents

Therapeutic anti-fungal nail preparation

Info

Publication number
IL143156A
IL143156A IL14315699A IL14315699A IL143156A IL 143156 A IL143156 A IL 143156A IL 14315699 A IL14315699 A IL 14315699A IL 14315699 A IL14315699 A IL 14315699A IL 143156 A IL143156 A IL 143156A
Authority
IL
Israel
Prior art keywords
dmso
solution
miconazole
ibuprofen
polyglycol
Prior art date
Application number
IL14315699A
Other languages
English (en)
Other versions
IL143156A0 (en
Original Assignee
Astan Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astan Inc filed Critical Astan Inc
Publication of IL143156A0 publication Critical patent/IL143156A0/xx
Publication of IL143156A publication Critical patent/IL143156A/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4151,2-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL14315699A 1998-11-16 1999-11-15 Therapeutic anti-fungal nail preparation IL143156A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/193,073 US6159977A (en) 1998-11-16 1998-11-16 Therapeutic anti-fungal nail preparation
PCT/US1999/027053 WO2000028821A1 (en) 1998-11-16 1999-11-15 Therapeutic anti-fungal nail preparation

Publications (2)

Publication Number Publication Date
IL143156A0 IL143156A0 (en) 2002-04-21
IL143156A true IL143156A (en) 2005-11-20

Family

ID=22712177

Family Applications (1)

Application Number Title Priority Date Filing Date
IL14315699A IL143156A (en) 1998-11-16 1999-11-15 Therapeutic anti-fungal nail preparation

Country Status (12)

Country Link
US (2) US6159977A (xx)
EP (1) EP1130964B1 (xx)
JP (1) JP2003535020A (xx)
CN (1) CN1181738C (xx)
AT (1) ATE309032T1 (xx)
AU (1) AU771851B2 (xx)
BR (1) BR9915394A (xx)
CA (1) CA2351536C (xx)
DE (1) DE69928278T2 (xx)
IL (1) IL143156A (xx)
MX (1) MXPA01004908A (xx)
WO (1) WO2000028821A1 (xx)

Families Citing this family (80)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6605751B1 (en) 1997-11-14 2003-08-12 Acrymed Silver-containing compositions, devices and methods for making
US6635676B2 (en) * 1999-04-28 2003-10-21 Regents Of The University Of Michigan Non-toxic antimicrobial compositions and methods of use
US7655252B2 (en) 1999-04-28 2010-02-02 The Regents Of The University Of Michigan Antimicrobial nanoemulsion compositions and methods
US6541517B1 (en) * 1999-09-03 2003-04-01 Donald M. Murphy Treatment of skin disorders
US8679523B2 (en) 1999-12-30 2014-03-25 Kimberly-Clark Worldwide, Inc. Oxygen-delivery closed cell foam matrix for wound treatment
US7074392B1 (en) 2000-03-27 2006-07-11 Taro Pharmaceutical Industries Limited Controllled delivery system of antifungal and keratolytic agents for local treatment of fungal infections
US8257688B2 (en) * 2000-03-27 2012-09-04 Taro Pharmaceuticals Industries Controlled delivery system of antifungal and keratolytic agents for local treatment of fungal infections of the nail and surrounding tissues
US6878365B2 (en) * 2001-03-10 2005-04-12 James Edward Brehove Topical application for treating toenail fungus
GB0108082D0 (en) * 2001-03-30 2001-05-23 Novartis Consumer Health Sa Topical composition
JP2010209109A (ja) * 2001-06-25 2010-09-24 Regents Of The Univ Of Michigan 抗微生物ナノエマルジョンの組成物および方法
CA2468539C (en) * 2001-10-22 2013-01-08 Michael A. Repka Delivery of medicaments to the nail
US20030144625A1 (en) * 2002-01-28 2003-07-31 Garry Sherman Method and apparatus for the treatment of infections of the nail matrix and nail plate
US6921529B2 (en) * 2002-07-29 2005-07-26 Joseph C. Maley Treatment modality and method for fungal nail infection
US8486426B2 (en) 2002-07-29 2013-07-16 Kimberly-Clark Worldwide, Inc. Methods and compositions for treatment of dermal conditions
US7374772B2 (en) * 2002-11-07 2008-05-20 Bommarito Alexander A Topical antifungal treatment
US20040126343A1 (en) * 2002-12-26 2004-07-01 Garshowitz Solomon David Nail drug delivery
US7311928B2 (en) * 2003-12-09 2007-12-25 Briant Burke Topical compositions containing tea tree oil for treatment of viral lesions
US8361553B2 (en) 2004-07-30 2013-01-29 Kimberly-Clark Worldwide, Inc. Methods and compositions for metal nanoparticle treated surfaces
CN101010003B (zh) 2004-07-30 2012-07-04 金佰利-克拉克国际公司 抗微生物的银组合物
CN101010004B (zh) 2004-07-30 2012-10-03 金伯利-克拉克环球有限公司 抗微生物的装置和组合物
EP1809264B1 (en) 2004-09-20 2016-04-13 Avent, Inc. Antimicrobial amorphous compositions
US20060078580A1 (en) 2004-10-08 2006-04-13 Mediquest Therapeutics, Inc. Organo-gel formulations for therapeutic applications
US7740875B2 (en) * 2004-10-08 2010-06-22 Mediquest Therapeutics, Inc. Organo-gel formulations for therapeutic applications
US20060275230A1 (en) 2004-12-10 2006-12-07 Frank Kochinke Compositions and methods for treating conditions of the nail unit
CA2590136A1 (en) * 2004-12-10 2006-06-15 Talima Therapeutics, Inc. Compositions and methods for treating conditions of the nail unit
US20060251593A1 (en) * 2005-04-07 2006-11-09 Work By Docs, Inc. Colored nail enamel treatment
JP2010279384A (ja) * 2005-08-31 2010-12-16 Pola Pharma Inc 抗真菌剤
US20090215888A1 (en) * 2006-03-02 2009-08-27 Singh Jagat Topical nail formulation
US8293965B2 (en) 2006-04-28 2012-10-23 Kimberly-Clark Worldwide, Inc. Antimicrobial site dressings
DK2018164T3 (en) 2006-05-12 2017-06-12 Christian Noe Use of combination preparations comprising antimycotics
WO2008137747A1 (en) 2007-05-02 2008-11-13 The Regents Of The University Of Michigan Nanoemulsion therapeutic compositions and methods of using the same
US20110082118A1 (en) * 2007-06-19 2011-04-07 Bhiku Patel Onychomycosis Treatment Delivery System
US20110076261A1 (en) * 2007-06-19 2011-03-31 Bhiku Patel Antifungal Drug Delivery System
WO2008156798A1 (en) * 2007-06-19 2008-12-24 Prugen, Inc. Drug combination for the treatment of skin disorders
US20090175810A1 (en) 2008-01-03 2009-07-09 Gareth Winckle Compositions and methods for treating diseases of the nail
US9320921B2 (en) * 2008-12-22 2016-04-26 Karen C. Swenholt Nail fungus treatment and composition
EP2376089B1 (en) 2008-11-17 2018-03-14 The Regents of the University of Michigan Cancer vaccine compositions and methods of using the same
WO2010093992A1 (en) * 2009-02-13 2010-08-19 Topica Pharmaceuticals, Inc Anti-fungal formulation
NL1036661C2 (en) 2009-03-04 2010-09-07 Serrix B V Anti-fungal compounds & compositions.
GB0907553D0 (en) 2009-05-01 2009-06-10 Insense Ltd Treatment of human or animal body surface infection
US20100292333A1 (en) * 2009-05-15 2010-11-18 bioCEPTA Corporation Compositions suitable for the topical treatment of fungal infections of the skin and nails
KR101656121B1 (ko) 2010-03-17 2016-09-08 노바리크 게엠베하 안압 증가를 치료하기 위한 약학 조성물
SI23311A (sl) * 2010-03-19 2011-09-30 Kemijski inštitut Farmacevtska kombinacija acetilsalicilne kisline in protiglivne substance za uničevanje ali inhibicijo rasti in replikacije gliv
ES2369101B2 (es) 2010-05-07 2012-08-02 Universidade De Santiago De Compostela Sistema farmacéutico acuoso para la administración de fármacos en las uñas.
EP2444063A1 (en) 2010-10-20 2012-04-25 Novaliq GmbH Liquid pharmaceutical compositions for the delivery of active ingredients
EP2462921A1 (en) 2010-11-11 2012-06-13 Novaliq GmbH Liquid pharmaceutical compositions for the treatment of a posterior eye disease
WO2012126899A2 (en) * 2011-03-18 2012-09-27 Katholieke Universiteit Leuven Ku Leuven Research & Development Inhibition and treatment of biofilms
EP3348272B1 (en) 2011-05-11 2020-06-24 Veloce BioPharma LLC Composition for use in the treatment of paronychia
AU2012260787B2 (en) 2011-05-25 2017-02-02 Dermaliq Therapeutics, Inc. Topical pharmaceutical composition based on semifluorinated alkanes
JP6023181B2 (ja) 2011-05-25 2016-11-09 ノバリック ゲーエムベーハー 爪に投与するための医薬組成物
EP2806886B1 (en) 2012-01-23 2017-03-01 Novaliq GmbH Stabilised protein compositions based on semifluorinated alkanes
WO2013122637A1 (en) * 2012-02-17 2013-08-22 Capriotti Joseph Antifungal compositions for the treatment of skin and nails
CA2775393C (en) * 2012-05-02 2014-04-29 Samy Saad Topical non-aqueous pharmaceutical formulations
CN104755073B (zh) 2012-09-12 2017-12-26 诺瓦利克有限责任公司 半氟化烷烃组合物
CA2883002C (en) 2012-09-12 2019-05-21 Novaliq Gmbh Compositions comprising mixtures of semifluorinated alkanes
US8697753B1 (en) 2013-02-07 2014-04-15 Polichem Sa Method of treating onychomycosis
JP2016514024A (ja) 2013-03-14 2016-05-19 ハラックス,インコーポレイテッド 爪部の感染症、疾患または障害の治療方法
CN105555311B (zh) 2013-07-23 2021-10-08 诺瓦利克有限责任公司 稳定的抗体组合物
GB2518826A (en) * 2013-09-27 2015-04-08 Thanasis Athanasiou Composition
EP2952208A1 (en) 2014-06-04 2015-12-09 Universidade de Santiago de Compostela Hydroalcoholic system for nail treatment
PT3209319T (pt) 2014-10-21 2021-09-24 Hexima Ltd Um método de tratamento
MX2017009450A (es) 2015-01-20 2018-01-18 Veloce Biopharma Llc Composicion yodofora novedosa y metodos de uso.
WO2017044458A1 (en) * 2015-09-08 2017-03-16 The University Of Toledo Treatment of raynaud's phenomenon by inhibition of transient receptor potential melastatin-8 (trpm-8)
JP6642935B2 (ja) 2015-09-30 2020-02-12 ノバリック ゲーエムベーハー 眼投与用の半フッ素化化合物
DE202016008738U1 (de) 2015-09-30 2019-04-09 Novaliq Gmbh Semifluorierte Verbindungen und ihre Zusammensetzungen
PL3442480T3 (pl) 2016-06-23 2020-04-30 Novaliq Gmbh Sposób podawania miejscowego
US10251858B1 (en) 2016-08-08 2019-04-09 Marlinz Pharma, LLC Composition for treating fungal infections in nails
US10543276B2 (en) 2016-08-08 2020-01-28 Marlinz Pharma, LLC Topical compositions
CN109890374A (zh) 2016-09-22 2019-06-14 诺瓦利克有限责任公司 用于治疗睑缘炎的药物组合物
AU2017329983B2 (en) 2016-09-23 2022-05-05 Novaliq Gmbh Ophthalmic compositions comprising ciclosporin
WO2018117125A1 (ja) * 2016-12-19 2018-06-28 富士フイルム株式会社 経皮製剤
US20210212994A1 (en) * 2017-02-28 2021-07-15 Temple University-Of The Commonwealth System Of Higher Education Novel Econazole Nitrate Medical Patch and Methods of Use Thereof
BR112019021917A8 (pt) 2017-04-21 2023-03-21 Novaliq Gmbh Composições de iodo
WO2018206656A1 (en) 2017-05-12 2018-11-15 Novaliq Gmbh Pharmaceutical compositions comprosing semifluorinated alkanes for the treatment of contact lense-related conditions
BR112020006072A2 (pt) 2017-09-27 2020-10-06 Novaliq Gmbh composições oftalmáticas compreendendo latanoprost para uso no tratamento de doenças oculares
CN111182893A (zh) 2017-10-04 2020-05-19 诺瓦利克有限责任公司 包含f6h8的眼用组合物
WO2019166631A1 (en) 2018-03-02 2019-09-06 Novaliq Gmbh Pharmaceutical compositions comprising nebivolol
WO2020064556A1 (en) 2018-09-27 2020-04-02 Novaliq Gmbh Topical sunscreen formulation
WO2020074697A1 (en) 2018-10-12 2020-04-16 Novaliq Gmbh Ophthalmic composition for treatment of dry eye disease
CN110537545A (zh) * 2019-09-12 2019-12-06 青岛农业大学 噻康唑在制备用于防治植物病原菌的杀菌剂中的应用

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6048486B2 (ja) * 1976-01-01 1985-10-28 木場 常義 抗リウマチ剤
GB2105990B (en) * 1981-08-27 1985-06-19 Nitto Electric Ind Co Adhesive skin patches
US4608249A (en) * 1982-11-02 1986-08-26 Nitto Electric Industrial Co., Ltd. Hydrophilic therapeutic material
CA1236029A (en) * 1984-05-14 1988-05-03 Edmund Sandborn Pharmaceutical solutions comprising dimethyl sulfoxide
DE3520098A1 (de) * 1985-06-05 1986-12-11 Bayer Ag, 5090 Leverkusen Azolderivate enthaltende formulierungen sowie ihre verwendung zur atraumatischen nagelentfernung
EP0270316A3 (en) * 1986-12-04 1989-12-06 Pfizer Inc. Topical compositions comprising 1-substituted imidazoles and nsaids for treatment of acne
JP2797401B2 (ja) * 1989-04-19 1998-09-17 日産化学工業株式会社 爪用抗真菌剤組成物
US4927641A (en) * 1989-05-23 1990-05-22 Knight Gerald L Veterinary liniment and method
US5874479A (en) * 1991-03-01 1999-02-23 Warner-Lambert Company Therapeutic permeation enhanced-wound healing compositions and methods for preparing and using same
FR2673537B1 (fr) * 1991-03-08 1993-06-11 Oreal Utilisation d'agents de penetration hydrophiles dans les compositions dermatologiques pour le traitement des onychomycoses, et compositions correspondantes.
JP3259972B2 (ja) * 1991-11-29 2002-02-25 ゼリア新薬工業株式会社 トルナフタート含有抗真菌剤
ATE151272T1 (de) * 1991-12-12 1997-04-15 Lohmann Therapie Syst Lts Selbstklebendes laminat für fuss- und fingernägel
JPH07506367A (ja) * 1992-05-05 1995-07-13 ザ、プロクター、エンド、ギャンブル、カンパニー アクネ治療組成物
GB2275191B (en) * 1993-02-10 1996-11-27 Donald John Dear Use of antifungal compounds in the treatment of skin disorders
IL105600A (en) * 1993-05-04 1999-12-31 Allon Blank Pharmaceutical and cosmetic compositions with increased rate of transdermal penetration and antioxidation protection against degradation containing derivatives of thioglycolic and mercaptopropionic acids some such novel compounds and their use
DE4337945A1 (de) * 1993-11-06 1995-05-11 Labtec Gmbh Pflaster zur Behandlung von Nagelmykosen
IT1265001B1 (it) * 1993-12-16 1996-10-17 Zambon Spa Composizione farmaceutica per uso topico contenente acido (s)-2-(4- isobutilfenil) propionico

Also Published As

Publication number Publication date
CA2351536C (en) 2007-08-07
CN1359262A (zh) 2002-07-17
AU771851B2 (en) 2004-04-01
AU1725700A (en) 2000-06-05
DE69928278D1 (de) 2005-12-15
EP1130964B1 (en) 2005-11-09
DE69928278T2 (de) 2006-06-14
WO2000028821A1 (en) 2000-05-25
BR9915394A (pt) 2002-03-05
IL143156A0 (en) 2002-04-21
ATE309032T1 (de) 2005-11-15
MXPA01004908A (es) 2003-03-10
US6391879B1 (en) 2002-05-21
CN1181738C (zh) 2004-12-29
CA2351536A1 (en) 2000-05-25
US6159977A (en) 2000-12-12
EP1130964A4 (en) 2002-06-19
JP2003535020A (ja) 2003-11-25
EP1130964A1 (en) 2001-09-12

Similar Documents

Publication Publication Date Title
IL143156A0 (en) Therapeutic anti-fungal nail preparation
EP1401421B1 (en) Methods for the treatment of nail fungus and other microbial and mycotic conditions and compositions useful therefor
HK1083009A1 (en) Topical drug delivery using phosphatidylcholine
EP1138314A3 (en) Controlled delivery system of antifungal and keratolytic agents for local treatment of fungal infections of the nail and surrounding tissues
ES2157307T3 (es) Composicion topica que contiene un antagonista de sustancia p.
HK1085390A1 (en) Solution for ungual and peri-ungual application and its use in preparation of a medicament treating dermatological diseases
BR0209658A (pt) Derivados de 4-amino-5-fenil-7-1ciclobutil-pirrolo [2,3-d] pirimidina
SE9703191D0 (sv) Medicament for improvement of duration of muscle function or treatment of muscle disorders or diseases
MXPA04000654A (es) Terapia dermica usando derivados de fosfato de agente de transferencia de electrones.
AU1079701A (en) Oral transmucosal drug dosage using solid solution
CA2260185A1 (en) Hormone replacement therapy drug formulations for topical application to the skin
GR77254B (xx)
MXPA02002249A (es) Composiciones farmaceuticas agradables al paladar para animales de compania.
KR950003919B1 (ko) 국소용 메트로니다졸 제제의 제조방법
WO2005007072A3 (en) Methods and pharmaceutical compositions for healing wounds
HUP9602498A2 (hu) Antimikrobiális hatású gyógyászati készítmények
US20180036227A1 (en) Topical compositions
AU2001261516A1 (en) Semi-solid delivery vehicle and pharmaceutical compositions
DE69935526D1 (de) Supramolekulare komplexe enthaltende arzneimittel
ES2137125A1 (es) La utilizacion de la sal de zinc del acido glicirretico en preparados contra el acne y las composiciones que contienen dicha sal.
IE810489L (en) Composition for topical application
WO2001007029A3 (en) Substituted guanidines and the use thereof
EP0717994A1 (en) New formulation for the topical treatment of psoriasis
MX9301537A (es) Composicion de resina de intercambio de iones.
CA2486704A1 (en) Anti-cancer formulation

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees