DE69923200D1 - Neue oral anzuwendende arzneizubereitungen für rivastigmine mit kontrollierter wirkstoffabgabe - Google Patents
Neue oral anzuwendende arzneizubereitungen für rivastigmine mit kontrollierter wirkstoffabgabeInfo
- Publication number
- DE69923200D1 DE69923200D1 DE69923200T DE69923200T DE69923200D1 DE 69923200 D1 DE69923200 D1 DE 69923200D1 DE 69923200 T DE69923200 T DE 69923200T DE 69923200 T DE69923200 T DE 69923200T DE 69923200 D1 DE69923200 D1 DE 69923200D1
- Authority
- DE
- Germany
- Prior art keywords
- rivastiggins
- active ingredients
- controlled active
- new oral
- preparations
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Emergency Medicine (AREA)
- Biomedical Technology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (13)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9821299 | 1998-10-01 | ||
GBGB9821299.6A GB9821299D0 (en) | 1998-10-01 | 1998-10-01 | Organic compounds |
GB9821298 | 1998-10-01 | ||
GBGB9821298.8A GB9821298D0 (en) | 1998-10-01 | 1998-10-01 | Organic compoundsq |
GB9826654 | 1998-12-03 | ||
GBGB9826654.7A GB9826654D0 (en) | 1998-12-03 | 1998-12-03 | Organic compounds |
GBGB9827624.9A GB9827624D0 (en) | 1998-12-16 | 1998-12-16 | Organic compounds |
GB9827624 | 1998-12-16 | ||
GB9907822 | 1999-04-06 | ||
GBGB9907823.0A GB9907823D0 (en) | 1999-04-06 | 1999-04-06 | Organic compounds |
GBGB9907822.2A GB9907822D0 (en) | 1999-04-06 | 1999-04-06 | Organic compounds |
GB9907823 | 1999-04-06 | ||
PCT/EP1999/007298 WO2000019985A2 (en) | 1998-10-01 | 1999-10-01 | New sustained release oral formulations |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69923200D1 true DE69923200D1 (de) | 2005-02-17 |
DE69923200T2 DE69923200T2 (de) | 2005-12-22 |
Family
ID=27547321
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69923200T Expired - Lifetime DE69923200T2 (de) | 1998-10-01 | 1999-10-01 | Neue oral anzuwendende arzneizubereitungen für rivastigmine mit kontrollierter wirkstoffabgabe |
Country Status (23)
Country | Link |
---|---|
US (5) | US20010033866A1 (de) |
EP (1) | EP1121104B1 (de) |
JP (1) | JP4012689B2 (de) |
KR (1) | KR100603900B1 (de) |
CN (1) | CN1406126A (de) |
AT (1) | ATE286725T1 (de) |
AU (1) | AU764866B2 (de) |
BR (1) | BR9914251A (de) |
CA (1) | CA2342340C (de) |
CZ (1) | CZ302888B6 (de) |
DE (1) | DE69923200T2 (de) |
ES (1) | ES2237163T3 (de) |
HK (1) | HK1052473A1 (de) |
HU (1) | HUP0103883A3 (de) |
ID (1) | ID27504A (de) |
IL (2) | IL141762A0 (de) |
NO (1) | NO331689B1 (de) |
NZ (1) | NZ510683A (de) |
PL (1) | PL196945B1 (de) |
PT (1) | PT1121104E (de) |
SK (1) | SK285250B6 (de) |
TR (1) | TR200100931T2 (de) |
WO (1) | WO2000019985A2 (de) |
Families Citing this family (64)
Publication number | Priority date | Publication date | Assignee | Title |
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ATE286725T1 (de) | 1998-10-01 | 2005-01-15 | Novartis Pharma Gmbh | Neue oral anzuwendende arzneizubereitungen für rivastigmine mit kontrollierter wirkstoffabgabe |
EP1133230A4 (de) * | 1998-11-23 | 2004-05-26 | Bonnie M Davis | Dosisformulierungen für acetylcholinesterase-inhibitoren |
WO2001013898A2 (en) * | 1999-08-26 | 2001-03-01 | Elan Corporation, Plc. | Pharmaceutical formulations with different release times |
GB9923045D0 (en) * | 1999-09-29 | 1999-12-01 | Novartis Ag | New oral formulations |
ATE361060T1 (de) * | 2000-09-29 | 2007-05-15 | Solvay Pharm Bv | Ionenstärkenunabhängige pharmazeutische formulierung mit verzögerter freisetzung |
JP5023412B2 (ja) * | 2001-05-09 | 2012-09-12 | 吉澤石灰工業株式会社 | ホルムアルデヒド廃液の処理剤 |
JP2005525299A (ja) * | 2001-09-14 | 2005-08-25 | スコラー インコーポレイテッド | アミノ酸調節性の長期放出投薬形態 |
PT1424997E (pt) * | 2001-09-14 | 2008-02-28 | Scolr Inc | Forma de dosagem de libertação prolongada modulada por aminoácidos |
KR100453288B1 (ko) * | 2002-03-12 | 2004-10-21 | 한국화학연구원 | 약물의 제어 방출을 위한 스퀴즈-유형의 삼투성 약물 전달장치 |
CN1681941A (zh) * | 2002-08-07 | 2005-10-12 | 诺瓦提斯公司 | 基于ApoE基因型治疗痴呆的方法 |
CA2521603A1 (en) * | 2003-04-07 | 2004-10-21 | Jurox Pty Ltd | Stable carprofen composition |
US20060105036A1 (en) | 2003-05-12 | 2006-05-18 | Stephen Peroutka | Threo-dops controlled release formulation |
US8158149B2 (en) * | 2004-05-12 | 2012-04-17 | Chelsea Therapeutics, Inc. | Threo-DOPS controlled release formulation |
RS51934B (en) * | 2003-08-08 | 2012-02-29 | Biovail Laboratories International Srl. | BUPROPION HYDROCHLORIDE TABLE WITH MODIFIED RELEASE |
US20100129310A1 (en) * | 2004-08-09 | 2010-05-27 | Pavak Rajnikanth Mehta | Stabilized desloratadine composition |
ES2403069T3 (es) * | 2005-02-22 | 2013-05-13 | Sun Pharma Advanced Research Company Ltd | Composición oral de liberación controlada que contiene levetiracetam |
EP1879583A2 (de) * | 2005-05-03 | 2008-01-23 | Mutual Pharmaceutical Company, Inc. | Chininformulierungen |
CA2620594C (en) * | 2005-09-01 | 2012-08-21 | Eisai R&D Management Co., Ltd. | Pharmaceutical composition having improved disintegratability |
GB0525461D0 (en) * | 2005-12-15 | 2006-01-25 | Archimedes Dev Ltd | Pharmaceutical compositions |
GB0606562D0 (en) * | 2006-03-31 | 2006-05-10 | Novartis Ag | Organic compounds |
US7803778B2 (en) | 2006-05-23 | 2010-09-28 | Theracos, Inc. | Glucose transport inhibitors and methods of use |
US8748419B2 (en) | 2006-06-16 | 2014-06-10 | Theracos, Inc. | Treating obesity with muscarinic receptor M1 antagonists |
US7893053B2 (en) | 2006-06-16 | 2011-02-22 | Theracos, Inc. | Treating psychological conditions using muscarinic receptor M1 antagonists |
AU2008232419B2 (en) | 2007-04-02 | 2013-06-20 | Theracos, Inc. | Benzylic glycoside derivatives and methods of use |
ITMI20071502A1 (it) * | 2007-07-25 | 2009-01-26 | Archimica Srl | Procedimento per la preparazione di formulazioni solide a rilascio controllato contenenti oxcarbazepina e formulazioni ottenibili con tale procedimento |
WO2009022345A1 (en) * | 2007-08-14 | 2009-02-19 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Phenyl carbamates for the treatment of multiple sclerosis |
JP4809931B2 (ja) | 2007-08-23 | 2011-11-09 | セラコス・インコーポレイテッド | ベンジルベンゼン誘導体およびその使用方法 |
US20100204303A1 (en) * | 2007-09-25 | 2010-08-12 | Idexx Laboratories, Inc. | Pharmaceutical Compositions for Administering Oligonucleotides |
WO2011034568A1 (en) | 2009-09-18 | 2011-03-24 | Chase Pharmaceuticals Corporation | Method and composition for treating alzheimer-type dementia |
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JP6071198B2 (ja) | 2008-07-15 | 2017-02-01 | テラコス,インコーポレーテッド | 重水素化ベンジルベンゼン誘導体及び使用方法 |
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CN101797236B (zh) * | 2010-03-23 | 2012-05-23 | 西南大学 | 重酒石酸卡巴拉汀口腔崩解片及其制备方法 |
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JP6285865B2 (ja) | 2011-11-14 | 2018-02-28 | アルファシグマ ソシエタ ペル アチオニ | うつ病を有する対象のための処置レジメンを選択するためのアッセイ及び方法 |
EP2892514A4 (de) | 2012-09-05 | 2016-04-13 | Chase Pharmaceuticals Corp | Neuroprotektive anticholinergische zusammensetzung und verfahren |
US10485800B2 (en) | 2012-11-30 | 2019-11-26 | The University Of Rochester | Mixed lineage kinase inhibitors for HIV/AIDS therapies |
KR20150098605A (ko) | 2012-12-21 | 2015-08-28 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 퀴놀린 유도체의 비정질 형태 및 그의 제조방법 |
KR102204279B1 (ko) | 2013-05-14 | 2021-01-15 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 자궁내막암 대상의 렌바티닙 화합물에 대한 반응성을 예측 및 평가하기 위한 생체표지 |
US10357486B2 (en) | 2013-08-16 | 2019-07-23 | Universiteit Maastricht | Treatment of cognitive impairment with PDE4 inhibitor |
WO2015136446A1 (en) | 2014-03-11 | 2015-09-17 | Nestec S.A. | Methods for selecting antidepressant drug therapy to treat depression |
CN103877063A (zh) * | 2014-03-24 | 2014-06-25 | 张绪伟 | 一种重酒石酸卡巴拉汀胶囊及其制备方法 |
RS63559B1 (sr) | 2014-08-28 | 2022-10-31 | Eisai R&D Man Co Ltd | Derivat hinolina velike čistoće i postupak za njegovu proizvodnju |
PL3263106T3 (pl) | 2015-02-25 | 2024-04-02 | Eisai R&D Management Co., Ltd. | Sposób tłumienia goryczy pochodnej chinoliny |
AU2015384801B2 (en) | 2015-03-04 | 2022-01-06 | Eisai R&D Management Co., Ltd. | Combination of a PD-1 antagonist and a VEGFR/FGFR/RET tyrosine kinase inhibitor for treating cancer |
KR101990951B1 (ko) * | 2015-04-27 | 2019-06-20 | 주식회사 네비팜 | 리바스티그민 함유 서방출 의약조성물 |
BR112017027227B1 (pt) | 2015-06-16 | 2023-12-12 | Eisai R&D Management Co., Ltd | Agente anti-câncer |
IL243707A0 (en) | 2016-01-20 | 2016-05-01 | Galmed Res And Dev Ltd | Treatment to regulate the microbiota in the intestine |
KR20190021180A (ko) * | 2017-08-22 | 2019-03-05 | 아주대학교산학협력단 | 퇴행성 신경질환 치료용 복합 제형 조성물 |
KR20190036370A (ko) | 2017-09-27 | 2019-04-04 | 서원대학교산학협력단 | 약물의 서방성 제형을 위한 약물전달체 |
KR20210057022A (ko) | 2018-07-30 | 2021-05-20 | 바이오테아 파르마, 아이엔씨. | 결정질 에피네프린 말로네이트염 |
CN112546037A (zh) * | 2020-12-08 | 2021-03-26 | 苏州大学 | 卡巴拉汀在制备抗辐射药中的应用 |
CN113398273B (zh) * | 2021-05-14 | 2022-07-19 | 广西壮族自治区中国科学院广西植物研究所 | 木聚糖衍生物作为亲水性缓释材料在制备药物缓释片中的应用 |
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ATE286725T1 (de) * | 1998-10-01 | 2005-01-15 | Novartis Pharma Gmbh | Neue oral anzuwendende arzneizubereitungen für rivastigmine mit kontrollierter wirkstoffabgabe |
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-
1999
- 1999-10-01 AT AT99950595T patent/ATE286725T1/de active
- 1999-10-01 HU HU0103883A patent/HUP0103883A3/hu unknown
- 1999-10-01 JP JP2000573347A patent/JP4012689B2/ja not_active Expired - Fee Related
- 1999-10-01 SK SK439-2001A patent/SK285250B6/sk not_active IP Right Cessation
- 1999-10-01 AU AU63321/99A patent/AU764866B2/en not_active Ceased
- 1999-10-01 BR BR9914251-1A patent/BR9914251A/pt not_active Application Discontinuation
- 1999-10-01 CZ CZ20011155A patent/CZ302888B6/cs not_active IP Right Cessation
- 1999-10-01 PT PT99950595T patent/PT1121104E/pt unknown
- 1999-10-01 CA CA002342340A patent/CA2342340C/en not_active Expired - Fee Related
- 1999-10-01 ID IDW20010671A patent/ID27504A/id unknown
- 1999-10-01 IL IL14176299A patent/IL141762A0/xx unknown
- 1999-10-01 ES ES99950595T patent/ES2237163T3/es not_active Expired - Lifetime
- 1999-10-01 PL PL348734A patent/PL196945B1/pl not_active IP Right Cessation
- 1999-10-01 KR KR1020017003384A patent/KR100603900B1/ko not_active IP Right Cessation
- 1999-10-01 CN CN99811633A patent/CN1406126A/zh active Pending
- 1999-10-01 DE DE69923200T patent/DE69923200T2/de not_active Expired - Lifetime
- 1999-10-01 WO PCT/EP1999/007298 patent/WO2000019985A2/en not_active Application Discontinuation
- 1999-10-01 NZ NZ510683A patent/NZ510683A/en not_active IP Right Cessation
- 1999-10-01 TR TR2001/00931T patent/TR200100931T2/xx unknown
- 1999-10-01 EP EP99950595A patent/EP1121104B1/de not_active Expired - Lifetime
-
2001
- 2001-03-01 IL IL141762A patent/IL141762A/en unknown
- 2001-03-22 NO NO20011471A patent/NO331689B1/no not_active IP Right Cessation
- 2001-03-27 US US09/818,690 patent/US20010033866A1/en not_active Abandoned
-
2002
- 2002-04-08 US US10/118,183 patent/US6565883B2/en not_active Expired - Fee Related
-
2003
- 2003-03-31 US US10/403,146 patent/US20030203025A1/en not_active Abandoned
- 2003-07-09 HK HK03104925.9A patent/HK1052473A1/zh unknown
-
2005
- 2005-04-14 US US11/105,967 patent/US20050175706A1/en not_active Abandoned
-
2006
- 2006-11-03 US US11/592,853 patent/US20070053982A1/en not_active Abandoned
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Representative=s name: KROHER, STROBEL RECHTS- UND PATENTANWAELTE, 80336 |
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Representative=s name: DR. SCHOEN & PARTNER, 80336 MUENCHEN |