DE69920473T2 - Neue fluoreszenzfarbstoffe und ihre anwendung in fluoreszenznachweisverfahren ganzer zellen für kaspasen, peptidasen, proteasen und andere enzyme sowie deren verwendung - Google Patents
Neue fluoreszenzfarbstoffe und ihre anwendung in fluoreszenznachweisverfahren ganzer zellen für kaspasen, peptidasen, proteasen und andere enzyme sowie deren verwendung Download PDFInfo
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- DE69920473T2 DE69920473T2 DE69920473T DE69920473T DE69920473T2 DE 69920473 T2 DE69920473 T2 DE 69920473T2 DE 69920473 T DE69920473 T DE 69920473T DE 69920473 T DE69920473 T DE 69920473T DE 69920473 T2 DE69920473 T2 DE 69920473T2
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- rhodamine
- pentafluorobenzoyl
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/78—Ring systems having three or more relevant rings
- C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
- C07D311/82—Xanthenes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0827—Tripeptides containing heteroatoms different from O, S, or N
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1027—Tetrapeptides containing heteroatoms different from O, S, or N
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
- Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
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| PCT/US1999/016423 WO2000004914A1 (en) | 1998-07-21 | 1999-07-21 | Novel fluorescence dyes and their applications for whole cell fluorescence screening assays for caspases, peptidases, proteases and other enzymes and the use thereof |
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| US8679836B2 (en) * | 2007-10-01 | 2014-03-25 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Methods of monitoring angiogenesis and metastasis in three dimensional co-cultures |
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-
1999
- 1999-07-21 AU AU51160/99A patent/AU5116099A/en not_active Abandoned
- 1999-07-21 DE DE69920473T patent/DE69920473T2/de not_active Expired - Fee Related
- 1999-07-21 WO PCT/US1999/016423 patent/WO2000004914A1/en active IP Right Grant
- 1999-07-21 EP EP99935751A patent/EP1100520B1/en not_active Expired - Lifetime
- 1999-07-21 AT AT99935751T patent/ATE276754T1/de not_active IP Right Cessation
- 1999-07-21 US US09/357,952 patent/US6248904B1/en not_active Expired - Lifetime
-
2002
- 2002-05-06 US US10/138,375 patent/US6984718B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP1100520A4 (en) | 2002-07-17 |
| AU5116099A (en) | 2000-02-14 |
| ATE276754T1 (de) | 2004-10-15 |
| DE69920473D1 (de) | 2004-10-28 |
| EP1100520A1 (en) | 2001-05-23 |
| US6984718B2 (en) | 2006-01-10 |
| WO2000004914A1 (en) | 2000-02-03 |
| US6248904B1 (en) | 2001-06-19 |
| EP1100520B1 (en) | 2004-09-22 |
| US20030208037A1 (en) | 2003-11-06 |
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