DE69916438D1 - Aminoanthracyclinonderivate und ihre verwendung zur behandlung von amyloidosis - Google Patents

Aminoanthracyclinonderivate und ihre verwendung zur behandlung von amyloidosis

Info

Publication number
DE69916438D1
DE69916438D1 DE69916438T DE69916438T DE69916438D1 DE 69916438 D1 DE69916438 D1 DE 69916438D1 DE 69916438 T DE69916438 T DE 69916438T DE 69916438 T DE69916438 T DE 69916438T DE 69916438 D1 DE69916438 D1 DE 69916438D1
Authority
DE
Germany
Prior art keywords
aminoanthracyclinone
derivatives
treating amyloidosis
amyloidosis
treating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69916438T
Other languages
English (en)
Inventor
Tiziano Bandiera
Daniele Fancelli
Mario Varasi
Michele Caruso
Jacqueline Lansen
Antonino Suarato
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Pharmacia Italia SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Italia SpA filed Critical Pharmacia Italia SpA
Application granted granted Critical
Publication of DE69916438D1 publication Critical patent/DE69916438D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/72Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 spiro-condensed with carbocyclic rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE69916438T 1998-03-10 1999-02-25 Aminoanthracyclinonderivate und ihre verwendung zur behandlung von amyloidosis Expired - Lifetime DE69916438D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9805080.0A GB9805080D0 (en) 1998-03-10 1998-03-10 Amino anthracyclinone derivatives
PCT/EP1999/001300 WO1999046254A2 (en) 1998-03-10 1999-02-25 Amino anthracyclinone derivatives and their use in the treatment of amyloidosis

Publications (1)

Publication Number Publication Date
DE69916438D1 true DE69916438D1 (de) 2004-05-19

Family

ID=10828304

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69916438T Expired - Lifetime DE69916438D1 (de) 1998-03-10 1999-02-25 Aminoanthracyclinonderivate und ihre verwendung zur behandlung von amyloidosis

Country Status (23)

Country Link
US (1) US6268362B1 (de)
EP (1) EP1062206B1 (de)
JP (1) JP2002506066A (de)
KR (1) KR100603798B1 (de)
CN (1) CN1113867C (de)
AR (1) AR019831A1 (de)
AT (1) ATE264302T1 (de)
AU (1) AU755754B2 (de)
BR (1) BR9908057A (de)
CA (1) CA2321834A1 (de)
DE (1) DE69916438D1 (de)
EA (1) EA003333B1 (de)
GB (1) GB9805080D0 (de)
HU (1) HUP0101046A3 (de)
ID (1) ID26084A (de)
IL (1) IL137677A (de)
NO (1) NO317260B1 (de)
NZ (1) NZ506945A (de)
PL (1) PL193245B1 (de)
TW (1) TW528751B (de)
UA (1) UA51838C2 (de)
WO (1) WO1999046254A2 (de)
ZA (1) ZA991839B (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITRM20110264A1 (it) * 2011-05-27 2012-11-28 Univ Degli Studi Milano Nuovi composti triciclici glicofusi, procedimento per la loro produzione e loro impiego quali ligandi dei peptidi ss amiloidi (ass).

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL110289A (en) 1993-08-06 1998-01-04 Policlinico San Matteo Istitut Pharmaceutical preparations containing 4-iodo-4-deoxydoxorubicin for the treatment of amyloidosis
GB9416007D0 (en) * 1994-08-08 1994-09-28 Erba Carlo Spa Anthracyclinone derivatives
GB9516349D0 (en) 1995-08-09 1995-10-11 Pharmacia Spa Aza-anthracyclinone derivatives
GB9613433D0 (en) * 1996-06-26 1996-08-28 Pharmacia Spa Fluoro labelled anthracyclinone and anthracycline derivatives

Also Published As

Publication number Publication date
HUP0101046A3 (en) 2002-12-28
IL137677A0 (en) 2001-10-31
EP1062206A2 (de) 2000-12-27
KR100603798B1 (ko) 2006-07-25
BR9908057A (pt) 2000-10-31
CA2321834A1 (en) 1999-09-16
WO1999046254A3 (en) 1999-10-21
PL344086A1 (en) 2001-09-24
ID26084A (id) 2000-11-23
NO20004406L (no) 2000-10-30
US6268362B1 (en) 2001-07-31
IL137677A (en) 2005-08-31
ATE264302T1 (de) 2004-04-15
HUP0101046A2 (hu) 2001-08-28
AU2930899A (en) 1999-09-27
KR20010041737A (ko) 2001-05-25
JP2002506066A (ja) 2002-02-26
ZA991839B (en) 1999-12-22
CN1291977A (zh) 2001-04-18
AU755754B2 (en) 2002-12-19
NZ506945A (en) 2002-06-28
UA51838C2 (uk) 2002-12-16
NO20004406D0 (no) 2000-09-04
CN1113867C (zh) 2003-07-09
WO1999046254A2 (en) 1999-09-16
AR019831A1 (es) 2002-03-20
GB9805080D0 (en) 1998-05-06
EA003333B1 (ru) 2003-04-24
PL193245B1 (pl) 2007-01-31
TW528751B (en) 2003-04-21
EA200000922A1 (ru) 2001-04-23
NO317260B1 (no) 2004-09-27
EP1062206B1 (de) 2004-04-14

Similar Documents

Publication Publication Date Title
DE69720463D1 (de) Sulfonamid-derivate und ihre verwendung zur behandlung von zns-erkrankungen
ATE241977T1 (de) Verwendung von anti-mikrotubuli mitteln zur behandlung von entzündlichen darmerkrankungen
DE69941566D1 (de) N-acetylhomotaurinate zur verwendung in der behandlung von hyperkinesie
DE69900249D1 (de) Pharmazeutische zusammensetzung von metformin und fibrat, und ihre verwendung zur behandlung von hyperglykämie
DE69836752D1 (de) Prostaglandinagoniste und deren verwendung zur behandlung von knochenerkrankungen
DE69715631D1 (de) Antikonvulsive sulfamatderivate zur behandlung von fettleibigkeit
DE69711067T2 (de) Antikonvulsiva zur verwendung bei der behandlung von amyotropischer lateralsklerose
DE69925306D1 (de) Behandlung von kohlenwasserstoffgas
DE60011570D1 (de) Arylpiperazinyl-cyclohexyl indolderivate zur behandlung von depressionen
DE60013859D1 (de) Indolderivate und deren verwendung zur behandlung von u.a. osteoporosis
ATE438630T1 (de) 5-sulfanyl-4h-1,2,4-triazolderivate und deren verwendung zur behandlung von somatostatine vermittelten krankheiten
DE69907802D1 (de) Thermisch wirkende Pflaster und seiner Verwendung
DE69916629D1 (de) Taurolidin und/oder taurultam zur behandlung von infektiösen ulcera oder gastritis
DE69734296D1 (de) Neue dikaffeoylchinasäurederivate und deren verwendung zur behandlung von hepatitis b
DE69716896T2 (de) Substituierte benzylamine-derivate und ihre verwendung zur behandlung von depression
DE60017133D1 (de) Naphthochinonderivate und ihre verwendung zur behandlung und kontrolle von tuberkulose
DE60027429D1 (de) Dihydrobenzodiazepinen und deren verwendung zur behandlung von dyslipidämien
ATE259818T1 (de) Substituierte tricyclische verbindungen und deren verwendung zur behandlung von spla2-bedingten erkrankungen
DE69620914D1 (de) Perfluoralkoxycycloalkancarbonylfluorid-zusammensetzungen und ihre verwendung
DE69939723D1 (de) Verwendung von Intereferon Gamma zur Behandlung von Herzhypertrophie
DE69931487D1 (de) Verwendung von apomorphin zur behandlung der vorzeitigen ejakulation
DE69708629T2 (de) Alkyloxyamin-substituierte fluorenonderivate und ihre verwendung als proteinkinase-c-inhibitoren
ATE433323T1 (de) Verwendung von erythropoietin zur behandlung von primärer hämochromatosen
DE69904849D1 (de) 3-tetrahydropyridin-4-yl-indole zur behandlung von psychotischen störungen
DE69812599D1 (de) Imino-aza-anthracyclonderivate zur behandlung von amyloidosis

Legal Events

Date Code Title Description
8332 No legal effect for de