DE69734296D1 - Neue dikaffeoylchinasäurederivate und deren verwendung zur behandlung von hepatitis b - Google Patents

Neue dikaffeoylchinasäurederivate und deren verwendung zur behandlung von hepatitis b

Info

Publication number
DE69734296D1
DE69734296D1 DE69734296T DE69734296T DE69734296D1 DE 69734296 D1 DE69734296 D1 DE 69734296D1 DE 69734296 T DE69734296 T DE 69734296T DE 69734296 T DE69734296 T DE 69734296T DE 69734296 D1 DE69734296 D1 DE 69734296D1
Authority
DE
Germany
Prior art keywords
dikaffeoylchinic
hepatitis
treatment
new
acid derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69734296T
Other languages
English (en)
Other versions
DE69734296T2 (de
Inventor
Junxing Dong
Zhongming Tang
Zhibao Mi
Bingji Wang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institute of Radiation Medicine of CAMMS
Original Assignee
Institute of Radiation Medicine of CAMMS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institute of Radiation Medicine of CAMMS filed Critical Institute of Radiation Medicine of CAMMS
Publication of DE69734296D1 publication Critical patent/DE69734296D1/de
Application granted granted Critical
Publication of DE69734296T2 publication Critical patent/DE69734296T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
DE69734296T 1996-08-29 1997-08-27 Neue dikaffeoylchinasäurederivate und deren verwendung zur behandlung von hepatitis b Expired - Lifetime DE69734296T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN96111691A CN1087608C (zh) 1996-08-29 1996-08-29 二咖啡酰奎宁酸在治疗乙型肝炎及与逆转录病毒有关疾病中的用途及新咖啡酰奎宁酸衍生物
CN96111691 1996-08-29
PCT/CN1997/000087 WO1998009599A2 (fr) 1996-08-29 1997-08-27 Utilisation d'un nouvel acide bicafeoylquinique dans le traitement de l'hepatite b et des maladies liees a des retrovirus, et derives de cet acide bicafeolyquinique

Publications (2)

Publication Number Publication Date
DE69734296D1 true DE69734296D1 (de) 2006-02-09
DE69734296T2 DE69734296T2 (de) 2006-07-06

Family

ID=5121229

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69734296T Expired - Lifetime DE69734296T2 (de) 1996-08-29 1997-08-27 Neue dikaffeoylchinasäurederivate und deren verwendung zur behandlung von hepatitis b

Country Status (8)

Country Link
US (1) US6331565B1 (de)
EP (1) EP1008344B1 (de)
JP (1) JP4219986B2 (de)
CN (1) CN1087608C (de)
AU (1) AU4008597A (de)
BR (1) BR9711647A (de)
DE (1) DE69734296T2 (de)
WO (1) WO1998009599A2 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1093529C (zh) * 1999-04-16 2002-10-30 中国人民解放军军事医学科学院放射医学研究所 1，5－二－o－咖啡酰奎宁酸衍生物的制备方法
WO2001076614A1 (fr) * 2000-04-10 2001-10-18 Takara Bio Inc. Remedes
US6632459B2 (en) 2000-12-11 2003-10-14 Nutricia N.V. Chlorogenic acid and an analog thereof for immune system stimulation
CN100341500C (zh) * 2004-09-29 2007-10-10 中国人民解放军军事医学科学院放射与辐射医学研究所 含二咖啡酰奎尼酸的乳剂及其制备方法
CN100353938C (zh) * 2004-09-29 2007-12-12 中国人民解放军军事医学科学院放射与辐射医学研究所 含二咖啡酰奎尼酸的组合物及其制备方法
EP1671535A1 (de) 2004-12-16 2006-06-21 Stiftung Caesar Center of Advanced European Studies and Research Verfahren zur Änderung des Gehaltes phenolischer Verbindungen in Pflanzenzellen
JP4586119B2 (ja) * 2005-10-28 2010-11-24 独立行政法人科学技術振興機構 Ｃ型肝炎ウイルス産生抑制材料とその製法
CN1899279A (zh) * 2005-07-22 2007-01-24 四川九章生物化工科技发展有限公司 绿原酸在制备具有保护肝脏功效药物的用途
CN1879727B (zh) * 2006-05-09 2010-04-21 中国科学院上海药物研究所 新型抗乙肝病毒抑制剂及其应用
CN101185668A (zh) * 2006-11-15 2008-05-28 广州联创思远利生物科技有限公司 一种新的防治艾滋病及保肝解毒制剂
JP4621855B2 (ja) * 2007-01-17 2011-01-26 雲海酒造株式会社 肝臓保護剤、肝がん発症抑制剤、及びそれらの医薬組成物
CN101245068A (zh) 2007-02-14 2008-08-20 浙江医药股份有限公司新昌制药厂 结晶型态的恩替卡韦及其制备方法和其药物组合物及用途
CN101284799B (zh) * 2007-03-23 2013-04-03 浙江医药股份有限公司新昌制药厂 咖啡酰奎宁酸含氮衍生物及其制备方法和其药物组合物及用途
CN101397333A (zh) 2007-09-27 2009-04-01 浙江医药股份有限公司新昌制药厂 去羟基万古霉素及其制备方法、和其药物组合物及其用途
FR2926955B1 (fr) 2008-02-01 2012-07-20 Agronomique Inst Nat Rech Procede de preparation d'acides dicafeoylquiniques et leur utilisation dans la lutte contre les pucerons
CN101828693B (zh) 2009-03-09 2013-01-02 浙江医药股份有限公司新昌制药厂 制备低粘度高流动性类胡萝卜素油悬浮液的方法及其应用
CN101829077B (zh) * 2010-05-26 2012-01-18 中国药科大学 二咖啡酰奎尼酸衍生物在制备用于治疗支原体感染疾病药物中的用途
CN114652710A (zh) * 2022-04-01 2022-06-24 北京济全生物科技有限公司 1,3-二咖啡酰奎宁酸在用于制备治疗肝癌的药物中的应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1050371B (it) * 1973-07-05 1981-03-10 Simes Composizione farmaceutica per il trattamento delle malattie del fegato
US6355684B1 (en) * 1990-10-11 2002-03-12 Meryl J. Squires Antimicrobial treatment for herpes simplex virus and other infectious diseases
FR2693105B1 (fr) * 1992-07-01 1994-09-02 Oreal Composition cosmétique et/ou dermatologique à action dépigmentante contenant un acide di- ou tri-caféoylquinique ou un mélange de ceux-ci.

Also Published As

Publication number Publication date
JP2000517323A (ja) 2000-12-26
WO1998009599A2 (fr) 1998-03-12
WO1998009599A3 (fr) 1998-06-04
EP1008344B1 (de) 2005-09-28
BR9711647A (pt) 2000-06-06
JP4219986B2 (ja) 2009-02-04
US6331565B1 (en) 2001-12-18
AU4008597A (en) 1998-03-26
EP1008344A4 (de) 2003-09-17
CN1175411A (zh) 1998-03-11
EP1008344A2 (de) 2000-06-14
CN1087608C (zh) 2002-07-17
DE69734296T2 (de) 2006-07-06

Similar Documents

Publication Publication Date Title
DE69836752D1 (de) Prostaglandinagoniste und deren verwendung zur behandlung von knochenerkrankungen
DE69734296D1 (de) Neue dikaffeoylchinasäurederivate und deren verwendung zur behandlung von hepatitis b
DE69927971D1 (de) Verwendung von peg-ifn-alpha und ribavirin zur behandlung chronischer hepatitis c
DE69622074D1 (de) Cystin-Silikon-Copolymere und deren Verwendung zur Behandlung von keratinischen Materialien
DE69720463T2 (de) Sulfonamid-derivate und ihre verwendung zur behandlung von zns-erkrankungen
DE69724016D1 (de) Verwendung von anti-mikrotubuli mitteln zur behandlung von entzündlichen erkrankungen der atemwege
DE69115921D1 (de) Verfahren zur behandlung und verwendung von abfallstoffen
DE59504187D1 (de) Verfahren zur Herstellung von ultrareinem Bisphenol-A und dessen Verwendung
DE69840752D1 (de) Verwendung von coumarine zur behandlung von lebererkrankungen und pankreaserkrankungen
DE69716896D1 (de) Substituierte benzylamine-derivate und ihre verwendung zur behandlung von depression
DE60027429D1 (de) Dihydrobenzodiazepinen und deren verwendung zur behandlung von dyslipidämien
DE69912670D1 (de) Substituierte tricyclische Verbindungen und deren Verwendung zur Behandlung von sPLA2-bedingten Erkrankungen
DE59606485D1 (de) Verfahren zur Herstellung von Poly-o-hydroxyamiden und Poly-o-mercaptoamiden
DE59606489D1 (de) Verfahren zur Herstellung von Poly-o-hydroxyamiden und Poly-o-mercaptoamiden
DE59606616D1 (de) Dicarbonsäurederivate und ihre Verwendung zur Herstellung von Poly-o-hydroxyamiden oder Poly-o-mercaptoamiden
DE69418931D1 (de) Verwendung von VIP und deren Analogen und Fragmenten zur Behandlung von neurodegenerativen Krankheiten
DE69930725D1 (de) Verfahren und kits zur behandlung von vulvovaginalen candidosen mit mikonazolnitrat
ATE346840T1 (de) Aminoalkylphenol-derivate zur behandlung von depression und gedächtnis-funktionsstörung
DE59510265D1 (de) Verfahren zur Herstellung von 2,6-Dichlor-3-fluor-benzonitril und neue Zwischen-produkte
DE59606657D1 (de) Verfahren zur Herstellung von Poly-o-hydroxyamiden und Poly-o-mercaptoamiden
DE59905059D1 (de) Verfahren zur Herstellung von Hydroxyethylcyclohexanen und Hydroxyethylpiperidinen
DE59606488D1 (de) Verfahren zur Herstellung von Poly-o-hydroxyamiden und Poly-o-mercaptoamiden
ATE235494T1 (de) Imino-aza-anthracyclonderivate zur behandlung von amyloidosis
DE59505276D1 (de) Verfahren zur Herstellung von 2-Chlor-6-nitrophenyl-alkylsulfanen und neue 2-Chlor-6-nitrophenyl-alkyl-sulfane
DE59510416D1 (de) Verfahren zur Herstellung von Chlormethylpyridin Derivaten und Acylaminomethylpyridine als Zwischenprodukte

Legal Events

Date Code Title Description
8364 No opposition during term of opposition