DE69915223T2 - Neue heterocyclische analoge von diphenylethylenverbindungen - Google Patents
Neue heterocyclische analoge von diphenylethylenverbindungen Download PDFInfo
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- DE69915223T2 DE69915223T2 DE69915223T DE69915223T DE69915223T2 DE 69915223 T2 DE69915223 T2 DE 69915223T2 DE 69915223 T DE69915223 T DE 69915223T DE 69915223 T DE69915223 T DE 69915223T DE 69915223 T2 DE69915223 T2 DE 69915223T2
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- PJANXHGTPQOBST-UHFFFAOYSA-N stilbene Chemical class C=1C=CC=CC=1C=CC1=CC=CC=C1 PJANXHGTPQOBST-UHFFFAOYSA-N 0.000 title abstract description 4
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- 125000005843 halogen group Chemical group 0.000 claims description 4
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- 125000004442 acylamino group Chemical group 0.000 claims description 3
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims description 3
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- IVAQJHSXBVHUQT-UHFFFAOYSA-N methyl 3-(3,5-dimethoxyphenyl)-2-[4-[4-[(2,4-dioxo-1,3-thiazolidin-5-yl)methyl]phenoxy]phenyl]prop-2-enoate Chemical compound C=1C=C(OC=2C=CC(CC3C(NC(=O)S3)=O)=CC=2)C=CC=1C(C(=O)OC)=CC1=CC(OC)=CC(OC)=C1 IVAQJHSXBVHUQT-UHFFFAOYSA-N 0.000 claims 1
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- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 4
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- 125000003358 C2-C20 alkenyl group Chemical group 0.000 description 2
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- 125000000959 isobutyl group Chemical group [H]C([H])([H])C([H])(C([H])([H])[H])C([H])([H])* 0.000 description 1
- 125000001972 isopentyl group Chemical group [H]C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C([H])([H])* 0.000 description 1
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- 125000004370 n-butenyl group Chemical group [H]\C([H])=C(/[H])C([H])([H])C([H])([H])* 0.000 description 1
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- 125000001971 neopentyl group Chemical group [H]C([*])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
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- ORTFAQDWJHRMNX-UHFFFAOYSA-M oxidooxomethyl Chemical compound [O-][C]=O ORTFAQDWJHRMNX-UHFFFAOYSA-M 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/34—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
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- Emergency Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Photoreceptors In Electrophotography (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US74925 | 1998-05-08 | ||
| US09/074,925 US6245814B1 (en) | 1998-05-08 | 1998-05-08 | Diphenylethylene compounds |
| US09/287,237 US6331633B1 (en) | 1998-05-08 | 1999-04-06 | Heterocyclic analogs of diphenylethylene compounds |
| US287237 | 1999-04-06 | ||
| PCT/US1999/009982 WO1999058127A1 (en) | 1998-05-08 | 1999-05-07 | Novel heterocyclic analogs of diphenylethylene compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69915223D1 DE69915223D1 (de) | 2004-04-08 |
| DE69915223T2 true DE69915223T2 (de) | 2005-01-27 |
Family
ID=26756222
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69915223T Expired - Lifetime DE69915223T2 (de) | 1998-05-08 | 1999-05-07 | Neue heterocyclische analoge von diphenylethylenverbindungen |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US6331633B1 (enExample) |
| EP (1) | EP1007039B1 (enExample) |
| JP (1) | JP4577985B2 (enExample) |
| KR (1) | KR100595919B1 (enExample) |
| CN (1) | CN1151139C (enExample) |
| AT (1) | ATE260906T1 (enExample) |
| AU (1) | AU751235C (enExample) |
| CA (1) | CA2295599C (enExample) |
| DE (1) | DE69915223T2 (enExample) |
| DK (1) | DK1007039T3 (enExample) |
| ES (1) | ES2216513T3 (enExample) |
| PT (1) | PT1007039E (enExample) |
| WO (1) | WO1999058127A1 (enExample) |
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-
1999
- 1999-04-06 US US09/287,237 patent/US6331633B1/en not_active Expired - Fee Related
- 1999-05-07 AU AU39741/99A patent/AU751235C/en not_active Ceased
- 1999-05-07 ES ES99922836T patent/ES2216513T3/es not_active Expired - Lifetime
- 1999-05-07 AT AT99922836T patent/ATE260906T1/de active
- 1999-05-07 DE DE69915223T patent/DE69915223T2/de not_active Expired - Lifetime
- 1999-05-07 DK DK99922836T patent/DK1007039T3/da active
- 1999-05-07 CA CA002295599A patent/CA2295599C/en not_active Expired - Fee Related
- 1999-05-07 KR KR1020007000173A patent/KR100595919B1/ko not_active Expired - Fee Related
- 1999-05-07 PT PT99922836T patent/PT1007039E/pt unknown
- 1999-05-07 EP EP99922836A patent/EP1007039B1/en not_active Expired - Lifetime
- 1999-05-07 WO PCT/US1999/009982 patent/WO1999058127A1/en not_active Ceased
- 1999-05-07 JP JP2000547978A patent/JP4577985B2/ja not_active Expired - Fee Related
- 1999-05-07 CN CNB998010170A patent/CN1151139C/zh not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ES2216513T3 (es) | 2004-10-16 |
| CN1273528A (zh) | 2000-11-15 |
| EP1007039A1 (en) | 2000-06-14 |
| CA2295599A1 (en) | 1999-11-18 |
| HK1028348A1 (en) | 2001-02-16 |
| CN1151139C (zh) | 2004-05-26 |
| CA2295599C (en) | 2009-01-20 |
| AU751235B2 (en) | 2002-08-08 |
| KR20010021615A (ko) | 2001-03-15 |
| ATE260906T1 (de) | 2004-03-15 |
| KR100595919B1 (ko) | 2006-07-03 |
| JP4577985B2 (ja) | 2010-11-10 |
| JP2002514598A (ja) | 2002-05-21 |
| US6331633B1 (en) | 2001-12-18 |
| DE69915223D1 (de) | 2004-04-08 |
| AU3974199A (en) | 1999-11-29 |
| AU751235C (en) | 2004-06-24 |
| EP1007039B1 (en) | 2004-03-03 |
| PT1007039E (pt) | 2004-07-30 |
| WO1999058127A1 (en) | 1999-11-18 |
| DK1007039T3 (da) | 2004-07-12 |
| EP1007039A4 (en) | 2002-05-22 |
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Owner name: THERACOS, INC., SUNNYVALE, CALIF., US |
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Representative=s name: PATENTANWAELTE EFFERT, BRESSEL UND KOLLEGEN, 12489 |
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