DE69904960D1 - Verfahren zur konservierung eines hämoglobin-blutersatzmittels - Google Patents

Verfahren zur konservierung eines hämoglobin-blutersatzmittels

Info

Publication number
DE69904960D1
DE69904960D1 DE69904960T DE69904960T DE69904960D1 DE 69904960 D1 DE69904960 D1 DE 69904960D1 DE 69904960 T DE69904960 T DE 69904960T DE 69904960 T DE69904960 T DE 69904960T DE 69904960 D1 DE69904960 D1 DE 69904960D1
Authority
DE
Germany
Prior art keywords
hemoglobin
blood
solution
substitute
polymerized
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69904960T
Other languages
English (en)
Other versions
DE69904960T2 (de
Inventor
S Gawryl
A Houtchens
R Light
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biopure Corp
Original Assignee
Biopure Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biopure Corp filed Critical Biopure Corp
Application granted granted Critical
Publication of DE69904960D1 publication Critical patent/DE69904960D1/de
Publication of DE69904960T2 publication Critical patent/DE69904960T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0236—Mechanical aspects
    • A01N1/0263—Non-refrigerated containers specially adapted for transporting or storing living parts whilst preserving, e.g. cool boxes, blood bags or "straws" for cryopreservation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B15/00—Layered products comprising a layer of metal
    • B32B15/04—Layered products comprising a layer of metal comprising metal as the main or only constituent of a layer, which is next to another layer of the same or of a different material
    • B32B15/08—Layered products comprising a layer of metal comprising metal as the main or only constituent of a layer, which is next to another layer of the same or of a different material of synthetic resin
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B27/00—Layered products comprising a layer of synthetic resin
    • B32B27/06—Layered products comprising a layer of synthetic resin as the main or only constituent of a layer, which is next to another layer of the same or of a different material
    • B32B27/08—Layered products comprising a layer of synthetic resin as the main or only constituent of a layer, which is next to another layer of the same or of a different material of synthetic resin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/795—Porphyrin- or corrin-ring-containing peptides
    • C07K14/805—Haemoglobins; Myoglobins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/10—Bag-type containers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Mechanical Engineering (AREA)
  • Hematology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Packages (AREA)
  • Peptides Or Proteins (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DE69904960T 1998-10-14 1999-10-13 Verfahren zur konservierung eines hämoglobin-blutersatzmittels Expired - Lifetime DE69904960T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/173,189 US6271351B1 (en) 1995-03-23 1998-10-14 Method for preserving a hemoglobin blood substitute
PCT/US1999/023631 WO2000021366A1 (en) 1998-10-14 1999-10-13 Method for preserving a hemoglobin blood substitute

Publications (2)

Publication Number Publication Date
DE69904960D1 true DE69904960D1 (de) 2003-02-20
DE69904960T2 DE69904960T2 (de) 2004-01-29

Family

ID=22630898

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69904960T Expired - Lifetime DE69904960T2 (de) 1998-10-14 1999-10-13 Verfahren zur konservierung eines hämoglobin-blutersatzmittels

Country Status (14)

Country Link
US (1) US6271351B1 (de)
EP (1) EP1121016B1 (de)
JP (1) JP4674358B2 (de)
CN (1) CN1233230C (de)
AT (1) ATE230924T1 (de)
AU (1) AU743248B2 (de)
CA (1) CA2346466A1 (de)
DE (1) DE69904960T2 (de)
DK (1) DK1121016T3 (de)
ES (1) ES2186418T3 (de)
HK (1) HK1041415B (de)
NZ (1) NZ511008A (de)
TW (1) TWI235662B (de)
WO (1) WO2000021366A1 (de)

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US6518010B2 (en) 2001-02-28 2003-02-11 Biopure Corporation Use of defibrinated blood for manufacture of a hemoglobin-based oxygen carrier
DE60234142D1 (de) * 2001-03-27 2009-12-10 Nipro Corp Albuminlösung enthaltender Kunststoffbehälter
US6974447B2 (en) * 2001-04-17 2005-12-13 Baxter International Inc. High gas barrier receptacle and closure assembly
AU2002254646B2 (en) * 2001-04-18 2008-05-15 Northfield Laboratories, Inc. Flexible container system for storage of stabilized hemoglobin solutions
CA2348042A1 (en) * 2001-06-04 2002-12-04 Ann Huletsky Sequences for detection and identification of methicillin-resistant staphylococcus aureus
US7001715B2 (en) 2002-02-28 2006-02-21 Biopure Corporation Purification of red blood cells by separation and diafiltration
JP2006502231A (ja) * 2002-10-03 2006-01-19 ノースフィールド ラボラトリーズ、インコーポレイテッド 大量失血を被っている患者の処置方法
JP2006516994A (ja) * 2003-01-29 2006-07-13 ノースフィールド ラボラトリーズ、インコーポレイテッド テトラマーの量を低下させた重合ヘモグロビン溶液及び調製するための方法
PT1663321E (pt) 2003-09-22 2012-11-15 Baxter Int Esterilização a alta pressão para esterilizar definitivamente preparações farmacêuticas e produtos médicos
US7135554B1 (en) * 2004-01-27 2006-11-14 Biopure Corporation Method of forming a polymerized hemoglobin solution from stabilized hemoglobin
JP2006164312A (ja) * 2004-12-02 2006-06-22 Hitachi Ltd 半導体装置およびそれを用いた磁気記録再生装置
US11834720B2 (en) 2005-10-11 2023-12-05 Geneohm Sciences, Inc. Sequences for detection and identification of methicillin-resistant Staphylococcus aureus (MRSA) of MREJ types xi to xx
US20070196810A1 (en) * 2006-01-24 2007-08-23 Northfield Laboratories Inc. Polymerized Hemoglobin Media and its Use in Isolation and Transplantation of Islet Cells
US20090004159A1 (en) * 2006-01-24 2009-01-01 The Board Of Trustees Of The University Of Illinoi Polymerized Hemoglobin Media and Its Use in Isolation and Transplantation of Islet Cells
CA2673357A1 (en) * 2006-12-19 2008-11-20 Geneohm Sciences, Inc. Detection of staphylococcus aureus and identification of methicillin-resistant staphylococcus aureus
US10172950B2 (en) 2009-06-09 2019-01-08 Prolong Pharmaceuticals, LLC Hemoglobin compositions
US10172949B2 (en) 2009-06-09 2019-01-08 Prolong Pharmaceuticals, LLC Hemoglobin compositions
BRPI1010775A2 (pt) 2009-06-09 2016-03-22 Prolong Pharmaceuticals Llc composição, método para preparar uma composição, e, uso de uma composição.
US20140004022A1 (en) * 2009-07-02 2014-01-02 Sio2 Medical Products, Inc. Pecvd coating of chromatography vials
US20110319858A1 (en) * 2010-06-23 2011-12-29 Bing Lou Wong Method for the preparation of a heat stable oxygen carrier-containing pharmaceutical compositions and the use thereof
EP2649096B1 (de) * 2010-12-08 2017-04-12 Boston Therapeutics, Inc. Hämoglobinzusammensetzungen und verfahren zu ihrer verwendung
CN103251998B (zh) * 2012-11-08 2015-09-02 亿京国际有限公司 用于血红蛋白氧载体(hboc)溶液的精确输注递送系统

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US4061736A (en) 1975-02-02 1977-12-06 Alza Corporation Pharmaceutically acceptable intramolecularly cross-linked, stromal-free hemoglobin
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US4001401A (en) 1975-02-02 1977-01-04 Alza Corporation Blood substitute and blood plasma expander comprising polyhemoglobin
US4053590A (en) 1975-02-27 1977-10-11 Alza Corporation Compositions of matter comprising macromolecular hemoglobin
DE7621615U1 (de) 1976-07-08 1977-02-03 Biotest-Serum-Institut Gmbh, 6000 Frankfurt Beutel zur aufnahme von blut und blutbestandteilen
US4140162A (en) 1977-07-28 1979-02-20 Baxter Travenol Lab Clear, autoclavable plastic formulation free of liquid plasticizers
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GB8710598D0 (en) 1987-05-05 1987-06-10 Star Medical Diagnostics Ltd Hemoglobin based blood substitute
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Also Published As

Publication number Publication date
TWI235662B (en) 2005-07-11
WO2000021366A1 (en) 2000-04-20
JP4674358B2 (ja) 2011-04-20
AU6424999A (en) 2000-05-01
US6271351B1 (en) 2001-08-07
ATE230924T1 (de) 2003-02-15
CN1233230C (zh) 2005-12-28
ES2186418T3 (es) 2003-05-01
NZ511008A (en) 2003-02-28
JP2002527360A (ja) 2002-08-27
CN1323159A (zh) 2001-11-21
HK1041415A1 (en) 2002-07-12
EP1121016A1 (de) 2001-08-08
DE69904960T2 (de) 2004-01-29
DK1121016T3 (da) 2003-02-24
HK1041415B (zh) 2006-08-04
AU743248B2 (en) 2002-01-24
EP1121016B1 (de) 2003-01-15
CA2346466A1 (en) 2000-04-20

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Legal Events

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