BRPI1010775A2 - composição, método para preparar uma composição, e, uso de uma composição. - Google Patents
composição, método para preparar uma composição, e, uso de uma composição.Info
- Publication number
- BRPI1010775A2 BRPI1010775A2 BRPI1010775A BRPI1010775A BRPI1010775A2 BR PI1010775 A2 BRPI1010775 A2 BR PI1010775A2 BR PI1010775 A BRPI1010775 A BR PI1010775A BR PI1010775 A BRPI1010775 A BR PI1010775A BR PI1010775 A2 BRPI1010775 A2 BR PI1010775A2
- Authority
- BR
- Brazil
- Prior art keywords
- composition
- preparing
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/41—Porphyrin- or corrin-ring-containing peptides
- A61K38/42—Haemoglobins; Myoglobins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/10—Inactivation or decontamination of a medicinal preparation prior to administration to an animal or a person
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US18554709P | 2009-06-09 | 2009-06-09 | |
PCT/US2010/038046 WO2010144629A1 (en) | 2009-06-09 | 2010-06-09 | Hemoglobin compositions |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI1010775A2 true BRPI1010775A2 (pt) | 2016-03-22 |
Family
ID=42779888
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI1010775A BRPI1010775A2 (pt) | 2009-06-09 | 2010-06-09 | composição, método para preparar uma composição, e, uso de uma composição. |
Country Status (31)
Country | Link |
---|---|
US (3) | US10080782B2 (pt) |
EP (2) | EP3266463B1 (pt) |
JP (3) | JP6227870B2 (pt) |
KR (4) | KR102170375B1 (pt) |
CN (1) | CN102458451B (pt) |
AR (1) | AR077041A1 (pt) |
AU (4) | AU2010258752B2 (pt) |
BR (1) | BRPI1010775A2 (pt) |
CA (1) | CA2764872C (pt) |
CL (1) | CL2011003091A1 (pt) |
CY (1) | CY1119578T1 (pt) |
DK (2) | DK3266463T3 (pt) |
ES (1) | ES2643462T3 (pt) |
HK (1) | HK1243628A1 (pt) |
HR (1) | HRP20171480T1 (pt) |
HU (1) | HUE037163T2 (pt) |
IL (1) | IL216404A (pt) |
LT (1) | LT2440239T (pt) |
ME (1) | ME02979B (pt) |
MX (1) | MX342787B (pt) |
MY (2) | MY184447A (pt) |
NO (1) | NO2440239T3 (pt) |
NZ (1) | NZ597022A (pt) |
PL (2) | PL2440239T3 (pt) |
PT (1) | PT2440239T (pt) |
RS (1) | RS56496B1 (pt) |
RU (1) | RU2589254C2 (pt) |
SI (1) | SI2440239T1 (pt) |
TW (1) | TWI626057B (pt) |
WO (1) | WO2010144629A1 (pt) |
ZA (1) | ZA201109176B (pt) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10172950B2 (en) | 2009-06-09 | 2019-01-08 | Prolong Pharmaceuticals, LLC | Hemoglobin compositions |
US10172949B2 (en) | 2009-06-09 | 2019-01-08 | Prolong Pharmaceuticals, LLC | Hemoglobin compositions |
MY184447A (en) | 2009-06-09 | 2021-04-01 | Prolong Pharmaceuticals Llc | Hemoglobin compositions |
US8609815B2 (en) * | 2010-09-02 | 2013-12-17 | Sangart, Inc. | Methods for preparing stable deoxygenated PEG-hemoglobin conjugate solutions comprising an antioxidant |
CN103491783A (zh) | 2011-01-14 | 2014-01-01 | 洛杉矶儿童医院 | 用于治疗包括镰状细胞疾病的疾病的一氧化碳溶液 |
ES2432075T3 (es) | 2011-07-23 | 2013-11-29 | Sastomed Gmbh | Espray para heridas |
US9572833B2 (en) | 2011-11-07 | 2017-02-21 | The General Hospital Corporation | Treatment of red blood cells |
US10729748B2 (en) * | 2012-01-13 | 2020-08-04 | Mölnlycke Health Care Ab | Scarring reducing wound treatment |
WO2013142135A1 (en) | 2012-03-20 | 2013-09-26 | Albert Einstein College Of Medicine Of Yeshiva University | Method of enhancing efficacy of blood transfusions |
US20150094267A1 (en) | 2012-04-03 | 2015-04-02 | Kim D. Vandegriff | Succinimide-activated nitroxyl compounds and methods for the use thereof for nitroxylation of proteins |
US20140106004A1 (en) | 2012-10-12 | 2014-04-17 | Bing Lou Wong | Hemoglobin-based oxygen carrier-containing pharmaceutical composition for cancer targeting treatment and prevention of cancer recurrence |
CA2906878C (en) * | 2013-03-15 | 2021-09-21 | Sangart, Inc. | Polyalkylene oxide valerate hemoglobin conjugates |
WO2014205077A1 (en) * | 2013-06-21 | 2014-12-24 | Prolong Pharmaceuticals, LLC | Hemoglobin compositions |
CN103387613B (zh) * | 2013-08-02 | 2016-12-28 | 西北大学 | 一种血红蛋白及血红蛋白氧载体病毒灭活的方法 |
CN103690978B (zh) * | 2013-12-19 | 2017-01-25 | 陕西佰美基因股份有限公司 | 一种用于血红蛋白及血红蛋白氧载体灭活病毒的方法 |
US20170333566A1 (en) * | 2014-11-14 | 2017-11-23 | Aima Biotech | Conjugated Proteins |
CN105749257B (zh) * | 2016-01-25 | 2019-12-06 | 四川大学华西医院 | 一种血红蛋白类携氧纳米凝胶及其制备方法和用途 |
CN107007625A (zh) * | 2016-01-27 | 2017-08-04 | 上海本素医药科技有限公司 | 含一氧化碳的血液制剂及其在制备抗炎症药物中的应用 |
AU2017267955B2 (en) * | 2016-05-19 | 2020-08-13 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Reduced oxygen carriers and their use for the treatment of carboxyhemoglobinemia |
US10662063B1 (en) * | 2016-06-06 | 2020-05-26 | University Of Puerto Rico | Photosensitized release of nitric oxide |
CN107625954A (zh) * | 2016-07-19 | 2018-01-26 | 上海本素医药科技有限公司 | 含一氧化碳的血红蛋白制剂及其在抗炎症中的应用 |
CN110636850A (zh) * | 2017-05-19 | 2019-12-31 | 新健康科学股份有限公司 | 创伤的方法和治疗 |
CN107952072B (zh) * | 2017-11-28 | 2021-07-20 | 深圳先进技术研究院 | 载药载氧杂交蛋白纳米粒的制备方法、载药载氧杂交蛋白纳米粒和应用 |
EP3993778A2 (en) | 2019-07-02 | 2022-05-11 | HB02 Therapeutics, LLC | Hemoglobin substitute mixtures including reconstituted plasma and platelets and their manufacture and use |
EP4138855A1 (en) * | 2020-04-23 | 2023-03-01 | Kalocyte, Inc. | Self-assembling oxygen carrier compositions |
JP2023531508A (ja) * | 2020-06-23 | 2023-07-24 | ヴィルテック バイオ,インク. | 出血性ショックを処置するための組成物および方法 |
EP4210732A1 (en) * | 2020-09-08 | 2023-07-19 | The Brigham & Women's Hospital, Inc. | Therapeutic carbon monoxide formulations |
WO2022184005A1 (en) | 2021-03-01 | 2022-09-09 | Billion King International Limited | Thiosuccinyl-crosslinked hemoglobin conjugates and methods of use and preparation thereof |
CN113813372A (zh) * | 2021-09-26 | 2021-12-21 | 云锦华彰(北京)生物科技有限公司 | 血红素组合物、药物组合物及其应用 |
WO2023091642A1 (en) * | 2021-11-18 | 2023-05-25 | Virginia Commonwealth University | Modular field-stable bio-artificial blood substitute |
CN113975378A (zh) * | 2021-11-19 | 2022-01-28 | 润方(北京)生物医药研究院有限公司 | 一种聚合血红蛋白在制备治疗缺血性脑卒中药物的应用 |
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US3991181A (en) | 1975-06-18 | 1976-11-09 | Warner-Lambert Company | Injectable stroma free hemoglobin solution and its method of manufacture |
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JPS57206622A (en) | 1981-06-10 | 1982-12-18 | Ajinomoto Co Inc | Blood substitute |
DE3481109D1 (de) | 1983-05-09 | 1990-03-01 | Novo Nordisk As | Antihaemophilie-faktor-viii-konzentrat und dessen herstellungsverfahren. |
US5281579A (en) * | 1984-03-23 | 1994-01-25 | Baxter International Inc. | Purified virus-free hemoglobin solutions and method for making same |
US4831012A (en) | 1984-03-23 | 1989-05-16 | Baxter International Inc. | Purified hemoglobin solutions and method for making same |
EP0206448B1 (en) * | 1985-06-19 | 1990-11-14 | Ajinomoto Co., Inc. | Hemoglobin combined with a poly(alkylene oxide) |
DK323587D0 (da) | 1987-06-25 | 1987-06-25 | Novo Industri As | Protein |
CA1312009C (en) | 1986-11-10 | 1992-12-29 | Carl W. Rausch | Extra pure semi-synthetic blood substitute |
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GB8710598D0 (en) | 1987-05-05 | 1987-06-10 | Star Medical Diagnostics Ltd | Hemoglobin based blood substitute |
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WO1989009784A1 (en) | 1988-04-08 | 1989-10-19 | Commonwealth Serum Laboratories Commission | Production of heat-stable factor viii concentrate |
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SE465222C5 (sv) | 1989-12-15 | 1998-02-10 | Pharmacia & Upjohn Ab | Ett rekombinant, humant faktor VIII-derivat och förfarande för dess framställning |
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US5376524A (en) | 1991-04-01 | 1994-12-27 | Thomas Jefferson University | Platelet storage medium containing acetate and phosphate |
DE4111393A1 (de) | 1991-04-09 | 1992-10-15 | Behringwerke Ag | Stabilisierte faktor viii-praeparationen |
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DE69231666T2 (de) | 1991-11-14 | 2001-05-10 | Brigham & Womens Hospital | Die nitrosylierung von enzym-sh gruppen als eine therapeutische massnahme |
IT1260468B (it) | 1992-01-29 | 1996-04-09 | Metodo per mantenere l'attivita' di enzimi proteolitici modificati con polietilenglicole | |
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SE9301581D0 (sv) | 1993-05-07 | 1993-05-07 | Kabi Pharmacia Ab | Protein formulation |
DE4321306A1 (de) | 1993-06-26 | 1995-01-05 | Sanol Arznei Schwarz Gmbh | Disulfide |
US5407579A (en) | 1993-07-02 | 1995-04-18 | National Science Council | Hemoglobin purification |
SE504074C2 (sv) | 1993-07-05 | 1996-11-04 | Pharmacia Ab | Proteinberedning för subkutan, intramuskulär eller intradermal administrering |
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US5919455A (en) | 1993-10-27 | 1999-07-06 | Enzon, Inc. | Non-antigenic branched polymer conjugates |
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US5932462A (en) | 1995-01-10 | 1999-08-03 | Shearwater Polymers, Inc. | Multiarmed, monofunctional, polymer for coupling to molecules and surfaces |
US5691452A (en) | 1995-03-23 | 1997-11-25 | Biopure Corporation | Method for preserving a hemoglobin blood substitute |
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