BRPI1012047A2 - compostos dímeros contendo oxazolidinona, composições e métodos para fazer e uso - Google Patents

compostos dímeros contendo oxazolidinona, composições e métodos para fazer e uso

Info

Publication number
BRPI1012047A2
BRPI1012047A2 BRPI1012047A BRPI1012047A BRPI1012047A2 BR PI1012047 A2 BRPI1012047 A2 BR PI1012047A2 BR PI1012047 A BRPI1012047 A BR PI1012047A BR PI1012047 A BRPI1012047 A BR PI1012047A BR PI1012047 A2 BRPI1012047 A2 BR PI1012047A2
Authority
BR
Brazil
Prior art keywords
oxazolidinone
compositions
making
methods
dimer compounds
Prior art date
Application number
BRPI1012047A
Other languages
English (en)
Inventor
Keith Hester D
Finn John
J Duguid Robert
Original Assignee
Trius Therapeutics
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Trius Therapeutics filed Critical Trius Therapeutics
Publication of BRPI1012047A2 publication Critical patent/BRPI1012047A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BRPI1012047A 2009-05-28 2010-05-27 compostos dímeros contendo oxazolidinona, composições e métodos para fazer e uso BRPI1012047A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US18195509P 2009-05-28 2009-05-28
US12/787,293 US8580767B2 (en) 2009-05-28 2010-05-25 Oxazolidinone containing dimer compounds, compositions and methods to make and use
PCT/US2010/036283 WO2010138649A1 (en) 2009-05-28 2010-05-27 Oxazolidinone containing dimer compounds, compositions and methods to make and use

Publications (1)

Publication Number Publication Date
BRPI1012047A2 true BRPI1012047A2 (pt) 2019-09-24

Family

ID=42333294

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI1012047A BRPI1012047A2 (pt) 2009-05-28 2010-05-27 compostos dímeros contendo oxazolidinona, composições e métodos para fazer e uso

Country Status (13)

Country Link
US (2) US8580767B2 (pt)
EP (1) EP2435051A1 (pt)
JP (2) JP5785939B2 (pt)
KR (1) KR101745511B1 (pt)
CN (2) CN103923122B (pt)
AU (1) AU2010254039B2 (pt)
BR (1) BRPI1012047A2 (pt)
CA (1) CA2769769A1 (pt)
IL (2) IL216547A0 (pt)
MX (2) MX2011012544A (pt)
NZ (2) NZ620552A (pt)
RU (2) RU2015122032A (pt)
WO (1) WO2010138649A1 (pt)

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* Cited by examiner, † Cited by third party
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KR100854211B1 (ko) 2003-12-18 2008-08-26 동아제약주식회사 신규한 옥사졸리디논 유도체, 그의 제조방법 및 이를유효성분으로 하는 항생제용 약학 조성물
ES2748505T3 (es) 2008-10-10 2020-03-17 Merck Sharp & Dohme Métodos para la preparación de oxazolidinonas y composiciones que las contienen
CU24089B1 (es) 2009-02-03 2015-04-29 Trius Therapeutics Forma cristalina del fosfato de dihidrógeno r)-3-(4-(2-(2-metiltretazol-5-il)-3-fluorofenil)-5-hidroximetil oxazolidin-2-ona
US8580767B2 (en) 2009-05-28 2013-11-12 Trius Therapeutics, Inc. Oxazolidinone containing dimer compounds, compositions and methods to make and use
CN105229001B (zh) * 2014-04-18 2017-04-26 杭州普晒医药科技有限公司 一种噁唑烷酮类抗生素的晶型及制备方法、组合物和用途
WO2016063246A1 (en) * 2014-10-22 2016-04-28 Sun Pharmaceutical Industries Limited Crystalline form r of tedizolid phosphate
WO2019118311A1 (en) 2017-12-13 2019-06-20 Merck Sharp & Dohme Corp. Pharmaceutical compositions of tedizolid phosphate
CN111825666B (zh) * 2019-04-23 2024-03-08 上海仕谱生物科技有限公司 二聚或多聚体形式的突变型idh抑制剂
IL299155A (en) 2020-06-18 2023-02-01 Akagera Medicines Inc Oxazolidinone compounds, liposome preparations containing oxazolidinone compounds and methods of using them

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US4128654A (en) * 1978-02-10 1978-12-05 E. I. Du Pont De Nemours And Company 5-Halomethyl-3-phenyl-2-oxazolidinones
US4340606A (en) 1980-10-23 1982-07-20 E. I. Du Pont De Nemours And Company 3-(p-Alkylsulfonylphenyl)oxazolidinone derivatives as antibacterial agents
FR2500450A1 (fr) * 1981-02-25 1982-08-27 Delalande Sa Nouveaux derives aminomethyl-5 oxazolidiniques, leur procede de preparation et leur application en therapeutique
US4461773A (en) * 1982-09-15 1984-07-24 E. I. Dupont De Nemours And Company P-Oxooxazolidinylbenzene compounds as antibacterial agents
CA1320730C (en) 1987-10-16 1993-07-27 The Du Pont Merck Pharmaceutical Company Aminomethyl oxooxazolidinyl aroylbenzene derivatives useful as antibacterial agents
US4948801A (en) * 1988-07-29 1990-08-14 E. I. Du Pont De Nemours And Company Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents
KR100257418B1 (ko) 1991-11-01 2000-05-15 로렌스 티. 마이젠헬더 치환된 아릴-및 헤테로아릴-페닐옥사졸리디논
SK283420B6 (sk) 1992-05-08 2003-07-01 Pharmacia & Upjohn Company Antimikrobiálne oxazolidinóny obsahujúce substituované diazínové skupiny
CZ288788B6 (cs) * 1992-12-08 2001-09-12 Pharmacia & Upjohn Company Antibakteriální fenyloxazolidinony substituované troponem
MY115155A (en) 1993-09-09 2003-04-30 Upjohn Co Substituted oxazine and thiazine oxazolidinone antimicrobials.
US5688792A (en) * 1994-08-16 1997-11-18 Pharmacia & Upjohn Company Substituted oxazine and thiazine oxazolidinone antimicrobials
ATE182142T1 (de) 1993-11-22 1999-07-15 Upjohn Co Substituierte hydroxyacetyl piperazine phenyl oxazolidinonsäureester
GB9702213D0 (en) * 1996-02-24 1997-03-26 Zeneca Ltd Chemical compounds
GB0009803D0 (en) * 2000-04-25 2000-06-07 Astrazeneca Ab Chemical compounds
CA2411859A1 (en) * 2000-06-05 2001-12-13 Jae-Gul Lee Novel oxazolidinone derivatives and a process for the preparation thereof
US20020115669A1 (en) * 2000-08-31 2002-08-22 Wiedeman Paul E. Oxazolidinone chemotherapeutic agents
DE60212959T2 (de) 2001-04-07 2007-02-15 Astrazeneca Ab Eine sulfonimid-gruppe enthaltende oxazolidinone als antibiotika
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DE60205030T2 (de) 2001-09-11 2006-04-20 Astrazeneca Ab Oxazolidinon- und/oder isoxazolinderivate als antibakterielle mittel
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NZ515881A (en) 2001-12-03 2004-09-24 New Zealand Dairy Board Cheese flavour ingredient and method of its production
MXPA04008312A (es) * 2002-02-28 2004-11-26 Astrazeneca Ab Derivados de 3-cilil-5-(anillo de 5 miembros que contienen nitrogeno)-metil-oxazolidinona y sus uso como agentes antibacterianos.
BR0308018A (pt) 2002-02-28 2005-01-04 Astrazeneca Ab Composto ou um seu sal farmaceuticamente aceitável ou um seu éster hidrolisável in vivo, pró-droga, método para produzir um efeito antibacteriano em um animal de sangue quente, uso de um composto ou um seu sal farmaceuticamente aceitável ou um seu éster hirolisável in vivo, composição farmacêutica, e, processo para a preparação de um composto ou um seu sal farmaceuticamente aceitável ou um seu éster hidrolisável in vivo
WO2004048392A1 (en) * 2002-11-28 2004-06-10 Astrazeneca Ab Oxazolidinone and / or isoxazoline derivatives as antibacterial agents
KR20050084010A (ko) * 2002-11-28 2005-08-26 아스트라제네카 아베 항균제로서의 옥사졸리디논
US7144911B2 (en) * 2002-12-31 2006-12-05 Deciphera Pharmaceuticals Llc Anti-inflammatory medicaments
US7202257B2 (en) * 2003-12-24 2007-04-10 Deciphera Pharmaceuticals, Llc Anti-inflammatory medicaments
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US7129259B2 (en) * 2003-12-17 2006-10-31 Rib-X Pharmaceuticals, Inc. Halogenated biaryl heterocyclic compounds and methods of making and using the same
KR100854211B1 (ko) 2003-12-18 2008-08-26 동아제약주식회사 신규한 옥사졸리디논 유도체, 그의 제조방법 및 이를유효성분으로 하는 항생제용 약학 조성물
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US20080021071A1 (en) * 2004-05-25 2008-01-24 Astrazeneca Ab 3-{4-(Pyridin-3-Yl) Phenyl}-5-(1H-1,2,3-Triazol-1-Ylmethyl)-1,3-Oxazolidin-2-Ones as Antibacterial Agents
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ES2748505T3 (es) * 2008-10-10 2020-03-17 Merck Sharp & Dohme Métodos para la preparación de oxazolidinonas y composiciones que las contienen
CU24089B1 (es) * 2009-02-03 2015-04-29 Trius Therapeutics Forma cristalina del fosfato de dihidrógeno r)-3-(4-(2-(2-metiltretazol-5-il)-3-fluorofenil)-5-hidroximetil oxazolidin-2-ona
US8580767B2 (en) 2009-05-28 2013-11-12 Trius Therapeutics, Inc. Oxazolidinone containing dimer compounds, compositions and methods to make and use

Also Published As

Publication number Publication date
IL239049A (en) 2017-07-31
US20140057874A1 (en) 2014-02-27
RU2557910C2 (ru) 2015-07-27
JP5785939B2 (ja) 2015-09-30
US20100305069A1 (en) 2010-12-02
KR20120026568A (ko) 2012-03-19
NZ596602A (en) 2014-02-28
KR101745511B1 (ko) 2017-06-20
JP2016026145A (ja) 2016-02-12
NZ620552A (en) 2015-08-28
JP2012528182A (ja) 2012-11-12
MX2011012544A (es) 2012-02-28
IL216547A0 (en) 2012-02-29
EP2435051A1 (en) 2012-04-04
AU2010254039B2 (en) 2016-03-03
CN102497866A (zh) 2012-06-13
US8580767B2 (en) 2013-11-12
IL239049A0 (en) 2015-07-30
JP6010196B2 (ja) 2016-10-19
CN103923122B (zh) 2016-08-24
CN102497866B (zh) 2014-09-17
CN103923122A (zh) 2014-07-16
AU2010254039A1 (en) 2011-12-15
WO2010138649A1 (en) 2010-12-02
RU2015122032A (ru) 2015-12-10
CA2769769A1 (en) 2010-12-02
MX2014001282A (es) 2014-06-10

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B25A Requested transfer of rights approved

Owner name: MERCK SHARP AND DOHME CORP. (US)

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2543 DE 01-10-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.