DE69836488D1 - Massenspektrometrischer nachweis von polypeptiden - Google Patents

Massenspektrometrischer nachweis von polypeptiden

Info

Publication number
DE69836488D1
DE69836488D1 DE69836488T DE69836488T DE69836488D1 DE 69836488 D1 DE69836488 D1 DE 69836488D1 DE 69836488 T DE69836488 T DE 69836488T DE 69836488 T DE69836488 T DE 69836488T DE 69836488 D1 DE69836488 D1 DE 69836488D1
Authority
DE
Germany
Prior art keywords
polypeptides
mass spectrometric
spectrometric detection
identity
target polypeptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69836488T
Other languages
English (en)
Inventor
Daniel Little
Hubert Koester
Scott Higgins
David Lough
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sequenom Inc
Original Assignee
Sequenom Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sequenom Inc filed Critical Sequenom Inc
Application granted granted Critical
Publication of DE69836488D1 publication Critical patent/DE69836488D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6818—Sequencing of polypeptides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6842—Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • G01N33/6851—Methods of protein analysis involving laser desorption ionisation mass spectrometry
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
DE69836488T 1997-09-02 1998-09-02 Massenspektrometrischer nachweis von polypeptiden Expired - Lifetime DE69836488D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/922,201 US6207370B1 (en) 1997-09-02 1997-09-02 Diagnostics based on mass spectrometric detection of translated target polypeptides
PCT/US1998/018311 WO1999012040A2 (en) 1997-09-02 1998-09-02 Mass spectrometric detection of polypeptides

Publications (1)

Publication Number Publication Date
DE69836488D1 true DE69836488D1 (de) 2007-01-04

Family

ID=25446684

Family Applications (3)

Application Number Title Priority Date Filing Date
DE19882657T Expired - Fee Related DE19882657C2 (de) 1997-09-02 1998-09-02 Massenspektrometrischer Nachweis von Polypeptiden
DE69836488T Expired - Lifetime DE69836488D1 (de) 1997-09-02 1998-09-02 Massenspektrometrischer nachweis von polypeptiden
DE69840878T Expired - Lifetime DE69840878D1 (de) 1997-09-02 1998-09-02 Massenspektrometrischer Nachweis von Polypeptiden

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE19882657T Expired - Fee Related DE19882657C2 (de) 1997-09-02 1998-09-02 Massenspektrometrischer Nachweis von Polypeptiden

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69840878T Expired - Lifetime DE69840878D1 (de) 1997-09-02 1998-09-02 Massenspektrometrischer Nachweis von Polypeptiden

Country Status (9)

Country Link
US (4) US6207370B1 (de)
EP (2) EP1296143B1 (de)
JP (1) JP2001515209A (de)
AT (2) ATE433112T1 (de)
AU (1) AU744266B2 (de)
CA (1) CA2300356A1 (de)
DE (3) DE19882657C2 (de)
NO (1) NO20001043L (de)
WO (1) WO1999012040A2 (de)

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US6207370B1 (en) 2001-03-27
EP1010008B1 (de) 2006-11-22
US6387628B1 (en) 2002-05-14
DE69840878D1 (de) 2009-07-16
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US6322970B1 (en) 2001-11-27
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ATE346304T1 (de) 2006-12-15
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