FR2709761B1 - Procédé de détection de molécules contenant des mésappariements nucléotidiques et de localisation de ces mésappariements, et application à la détection de substitutions ou de délétions de bases . - Google Patents

Procédé de détection de molécules contenant des mésappariements nucléotidiques et de localisation de ces mésappariements, et application à la détection de substitutions ou de délétions de bases .

Info

Publication number
FR2709761B1
FR2709761B1 FR9310821A FR9310821A FR2709761B1 FR 2709761 B1 FR2709761 B1 FR 2709761B1 FR 9310821 A FR9310821 A FR 9310821A FR 9310821 A FR9310821 A FR 9310821A FR 2709761 B1 FR2709761 B1 FR 2709761B1
Authority
FR
France
Prior art keywords
mismatches
deletions
locating
detection
application
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9310821A
Other languages
English (en)
Other versions
FR2709761A1 (fr
Inventor
Tommaso Meo
Mario Tosi
Elisabeth Verpy
Michel Biasotto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut Pasteur de Lille
Institut National de la Sante et de la Recherche Medicale INSERM
Original Assignee
Institut Pasteur de Lille
Institut National de la Sante et de la Recherche Medicale INSERM
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institut Pasteur de Lille, Institut National de la Sante et de la Recherche Medicale INSERM filed Critical Institut Pasteur de Lille
Priority to FR9310821A priority Critical patent/FR2709761B1/fr
Priority to PCT/FR1994/001068 priority patent/WO1995007361A1/fr
Priority to US08/605,163 priority patent/US5879886A/en
Priority to EP94926975A priority patent/EP0717781A1/fr
Priority to CA002171469A priority patent/CA2171469A1/fr
Publication of FR2709761A1 publication Critical patent/FR2709761A1/fr
Application granted granted Critical
Publication of FR2709761B1 publication Critical patent/FR2709761B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6858—Allele-specific amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
FR9310821A 1993-09-10 1993-09-10 Procédé de détection de molécules contenant des mésappariements nucléotidiques et de localisation de ces mésappariements, et application à la détection de substitutions ou de délétions de bases . Expired - Fee Related FR2709761B1 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
FR9310821A FR2709761B1 (fr) 1993-09-10 1993-09-10 Procédé de détection de molécules contenant des mésappariements nucléotidiques et de localisation de ces mésappariements, et application à la détection de substitutions ou de délétions de bases .
PCT/FR1994/001068 WO1995007361A1 (fr) 1993-09-10 1994-09-09 Procede de detection de molecules contenant des mesappariements nucleotidiques et de localisation de ces mesappariements, et application a la detection de substitutions ou de deletions de bases dans des sequences nucleotidiques
US08/605,163 US5879886A (en) 1993-09-10 1994-09-09 Method for detecting molecules containing nucleotide mismatches and the location of these mismatches, and application to the detection of base substitutions or deletions in nucleotide sequences
EP94926975A EP0717781A1 (fr) 1993-09-10 1994-09-09 Procede de detection de molecules contenant des mesappariements nucleotidiques et de localisation de ces mesappariements, et application a la detection de substitutions ou de deletions de bases dans des sequences nucleotidiques
CA002171469A CA2171469A1 (fr) 1993-09-10 1994-09-09 Procede de detection de molecules contenant des mesappariements nucleotidiques et de localisation de ces mesappariements, et application a la detection de substitutions ou de deletions de bases dans des sequences nucleotidiques

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9310821A FR2709761B1 (fr) 1993-09-10 1993-09-10 Procédé de détection de molécules contenant des mésappariements nucléotidiques et de localisation de ces mésappariements, et application à la détection de substitutions ou de délétions de bases .

Publications (2)

Publication Number Publication Date
FR2709761A1 FR2709761A1 (fr) 1995-03-17
FR2709761B1 true FR2709761B1 (fr) 1995-11-24

Family

ID=9450756

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9310821A Expired - Fee Related FR2709761B1 (fr) 1993-09-10 1993-09-10 Procédé de détection de molécules contenant des mésappariements nucléotidiques et de localisation de ces mésappariements, et application à la détection de substitutions ou de délétions de bases .

Country Status (5)

Country Link
US (1) US5879886A (fr)
EP (1) EP0717781A1 (fr)
CA (1) CA2171469A1 (fr)
FR (1) FR2709761B1 (fr)
WO (1) WO1995007361A1 (fr)

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US5571388A (en) * 1984-03-29 1996-11-05 Li-Cor, Inc. Sequencing near infrared and infrared fluorescense labeled DNA for detecting using laser diodes and suitable labels thereof
US6207421B1 (en) 1984-03-29 2001-03-27 Li-Cor, Inc. DNA sequencing and DNA terminators
US6086737A (en) * 1984-03-29 2000-07-11 Li-Cor, Inc. Sequencing near infrared and infrared fluorescence labeled DNA for detecting using laser diodes and suitable labels therefor
US5360523A (en) * 1984-03-29 1994-11-01 Li-Cor, Inc. DNA sequencing
US4729947A (en) * 1984-03-29 1988-03-08 The Board Of Regents Of The University Of Nebraska DNA sequencing
US6004446A (en) * 1984-03-29 1999-12-21 Li-Cor, Inc. DNA Sequencing
EP1262564A3 (fr) 1993-01-07 2004-03-31 Sequenom, Inc. Séquençage d'adn par spectrométrie de masse
US5605798A (en) 1993-01-07 1997-02-25 Sequenom, Inc. DNA diagnostic based on mass spectrometry
CA2188660C (fr) * 1994-04-25 2005-01-18 Richard G. H. Cotton Detection de mutations par clivage par resolvase
NL9401082A (nl) * 1994-06-28 1996-02-01 Ingeny Bv Werkwijze voor het detecteren van mutaties.
EP0843736B1 (fr) * 1995-05-11 1999-12-22 Ulf Landegren Detection d'erreurs d'appariement par clivage de resolvase sur un support solide
EP0832283A2 (fr) * 1995-06-07 1998-04-01 Genzyme Corporation Methode d'identification de modification genetique d'adn consistant en un sequencage d'adn et un clonage de position
EP0832210B1 (fr) * 1995-06-07 2004-10-27 Trevigen, Inc. Procede dans lequel une enzyme de reparation d'acide nucleique est utilisee pour la detection de mutation ponctuelle et une mutagenese in vitro
US5656430A (en) * 1995-06-07 1997-08-12 Trevigen, Inc. Oscillating signal amplifier for nucleic acid detection
US5763178A (en) * 1995-06-07 1998-06-09 Trevigen, Inc. Oscillating signal amplifier for nucleic acid detection
US6146854A (en) * 1995-08-31 2000-11-14 Sequenom, Inc. Filtration processes, kits and devices for isolating plasmids
JP2000501615A (ja) * 1995-12-15 2000-02-15 アマーシャム・ライフ・サイエンス・インコーポレーテッド 酵素増幅中に生じる変異配列の検出および除去のためのミスマッチ修復系を用いる方法
US5670325A (en) * 1996-08-14 1997-09-23 Exact Laboratories, Inc. Method for the detection of clonal populations of transformed cells in a genomically heterogeneous cellular sample
DE19600362C2 (de) * 1996-01-08 1998-11-12 Wolf Prof Dr Bertling Verfahren zur Erfassung und Quantifizierung von Nucleinsäure-Molekülen
US5741650A (en) * 1996-01-30 1998-04-21 Exact Laboratories, Inc. Methods for detecting colon cancer from stool samples
US6051378A (en) * 1996-03-04 2000-04-18 Genetrace Systems Inc. Methods of screening nucleic acids using mass spectrometry
FR2746815A1 (fr) * 1996-03-26 1997-10-03 Pasteur Institut Sequences en amont du gene sm 22, vecteurs les contenant et leurs utilisations therapeutiques, notamment dans le traitement des maladies vasculaires
US6300077B1 (en) 1996-08-14 2001-10-09 Exact Sciences Corporation Methods for the detection of nucleic acids
US6203993B1 (en) 1996-08-14 2001-03-20 Exact Science Corp. Methods for the detection of nucleic acids
US6020137A (en) * 1996-08-14 2000-02-01 Exact Laboratories, Inc. Methods for the detection of loss of heterozygosity
US6146828A (en) * 1996-08-14 2000-11-14 Exact Laboratories, Inc. Methods for detecting differences in RNA expression levels and uses therefor
US5928870A (en) * 1997-06-16 1999-07-27 Exact Laboratories, Inc. Methods for the detection of loss of heterozygosity
US5952178A (en) 1996-08-14 1999-09-14 Exact Laboratories Methods for disease diagnosis from stool samples
US6100029A (en) * 1996-08-14 2000-08-08 Exact Laboratories, Inc. Methods for the detection of chromosomal aberrations
US5777324A (en) 1996-09-19 1998-07-07 Sequenom, Inc. Method and apparatus for maldi analysis
US6268136B1 (en) 1997-06-16 2001-07-31 Exact Science Corporation Methods for stool sample preparation
CA2268368A1 (fr) * 1997-08-28 1999-03-11 The Perkin-Elmer Corporation Detection amelioree de mutations dans des acides nucleiques, par clivage chimique
US6207370B1 (en) 1997-09-02 2001-03-27 Sequenom, Inc. Diagnostics based on mass spectrometric detection of translated target polypeptides
US6080544A (en) * 1998-02-13 2000-06-27 Ohio State University Methods for identifying nucleic acid mutations using mismatch modification
US6104028A (en) * 1998-05-29 2000-08-15 Genetrace Systems Inc. Volatile matrices for matrix-assisted laser desorption/ionization mass spectrometry
US6280947B1 (en) 1999-08-11 2001-08-28 Exact Sciences Corporation Methods for detecting nucleotide insertion or deletion using primer extension
US7166432B2 (en) * 1999-03-12 2007-01-23 Integragen Compositions and methods for genetic analysis
DE19911130A1 (de) 1999-03-12 2000-09-21 Hager Joerg Verfahren zur Identifikation chromosomaler Regionen und Gene
AU2002223591A1 (en) * 2000-10-06 2002-04-15 Axaron Bioscience Ag Method for mutational analysis
US6428964B1 (en) 2001-03-15 2002-08-06 Exact Sciences Corporation Method for alteration detection
EP1704246A4 (fr) * 2003-09-30 2007-11-28 Perkinelmer Las Inc Compositions et procedes de genotypage de polymorphismes d'un nucleotide simple
WO2006047787A2 (fr) 2004-10-27 2006-05-04 Exact Sciences Corporation Methode de surveillance de la progression ou la recurrence d'une maladie
WO2007044071A2 (fr) 2005-04-21 2007-04-19 Exact Sciences Corporation Analyse d'echantillons d'acide nucleique heterogenes

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Publication number Priority date Publication date Assignee Title
EP0317239A3 (fr) * 1987-11-13 1990-01-17 Native Plants Incorporated Procédé et dispositif pour la détection des polymorphismes de restriction des longueurs de fragments
US5217863A (en) * 1988-02-04 1993-06-08 Medical Research Council Detection of mutations in nucleic acids
WO1989011548A1 (fr) * 1988-05-20 1989-11-30 Cetus Corporation Sondes specifiques a des sequences immobilisees
WO1990013668A1 (fr) * 1989-05-05 1990-11-15 Lifecodes Corporation Methode pour l'analyse genetique d'un echantillon d'acide nucleique
US5556750A (en) * 1989-05-12 1996-09-17 Duke University Methods and kits for fractionating a population of DNA molecules based on the presence or absence of a base-pair mismatch utilizing mismatch repair systems
WO1993002216A1 (fr) * 1991-07-19 1993-02-04 Upstate Biotechnology, Inc. Procede de detection de mutations
US5376526A (en) * 1992-05-06 1994-12-27 The Board Of Trustees Of The Leland Stanford Junior University Genomic mismatch scanning

Also Published As

Publication number Publication date
CA2171469A1 (fr) 1995-03-16
EP0717781A1 (fr) 1996-06-26
FR2709761A1 (fr) 1995-03-17
WO1995007361A1 (fr) 1995-03-16
US5879886A (en) 1999-03-09

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