DE69828624T2 - Biologisch aktive verbindungen enthaltende multilamellare koaleszenzvesikel (mlcv) - Google Patents

Biologisch aktive verbindungen enthaltende multilamellare koaleszenzvesikel (mlcv) Download PDF

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Publication number
DE69828624T2
DE69828624T2 DE69828624T DE69828624T DE69828624T2 DE 69828624 T2 DE69828624 T2 DE 69828624T2 DE 69828624 T DE69828624 T DE 69828624T DE 69828624 T DE69828624 T DE 69828624T DE 69828624 T2 DE69828624 T2 DE 69828624T2
Authority
DE
Germany
Prior art keywords
mlcv
biologically active
active compound
vesicles
suv
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69828624T
Other languages
German (de)
English (en)
Other versions
DE69828624D1 (de
Inventor
T. Lawrence BONI
M. Michael BATENJANY
Stella Gevantmakher
C. Mircea Popescu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oncothyreon Canada Inc
Original Assignee
Biomira Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biomira Inc filed Critical Biomira Inc
Publication of DE69828624D1 publication Critical patent/DE69828624D1/de
Application granted granted Critical
Publication of DE69828624T2 publication Critical patent/DE69828624T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277—Preparation processes; Proliposomes
    • A61K9/1278—Post-loading, e.g. by ion or pH gradient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277—Preparation processes; Proliposomes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/906—Drug delivery
    • Y10S977/907—Liposome

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE69828624T 1997-10-01 1998-10-01 Biologisch aktive verbindungen enthaltende multilamellare koaleszenzvesikel (mlcv) Expired - Lifetime DE69828624T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US6060697P 1997-10-01 1997-10-01
US60606P 1997-10-01
PCT/US1998/020780 WO1999016426A2 (en) 1997-10-01 1998-10-01 Multilamellar coalescence vesicles (mlcv) containing biologically active compounds

Publications (2)

Publication Number Publication Date
DE69828624D1 DE69828624D1 (de) 2005-02-17
DE69828624T2 true DE69828624T2 (de) 2005-12-22

Family

ID=22030591

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69828624T Expired - Lifetime DE69828624T2 (de) 1997-10-01 1998-10-01 Biologisch aktive verbindungen enthaltende multilamellare koaleszenzvesikel (mlcv)

Country Status (9)

Country Link
US (1) US6544549B1 (enExample)
EP (1) EP1019026B1 (enExample)
JP (1) JP2001517693A (enExample)
AT (1) ATE286717T1 (enExample)
AU (1) AU745000B2 (enExample)
CA (1) CA2305533C (enExample)
DE (1) DE69828624T2 (enExample)
IN (1) IN190388B (enExample)
WO (1) WO1999016426A2 (enExample)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1857112B1 (en) * 2005-03-09 2013-05-15 Sunstar Inc. Anticancer composition comprising liposomes containing phytosterols
WO2007021822A2 (en) * 2005-08-09 2007-02-22 The Research Foundation Of State Of University Of New York At Buffalo Compositions and methods of preparation of liposomal microparticulate il-12
US20140271782A1 (en) 2013-03-15 2014-09-18 Dermazone Solutions, Inc. Method for preparing nanolipids with encapsulated alcohol
EP1973837B1 (en) * 2005-12-30 2017-04-19 Dermazone Solutions, Inc. Nanolipidic particles
WO2010059253A2 (en) 2008-11-24 2010-05-27 Massachusets Institute Of Technology Methods and compositions for localized agent delivery
US20100323018A1 (en) * 2009-06-17 2010-12-23 Massachusetts Institute Of Technology Branched DNA/RNA monomers and uses thereof
US20100324124A1 (en) * 2009-06-17 2010-12-23 Massachusetts Institute Of Technology Compositions and methods relating to DNA-based particles
SG184127A1 (en) 2010-03-19 2012-10-30 Massachusetts Inst Technology Lipid vesicle compositions and methods of use
US9149432B2 (en) 2010-03-19 2015-10-06 Massachusetts Institute Of Technology Lipid vesicle compositions and methods of use
US20110229556A1 (en) * 2010-03-19 2011-09-22 Massachusetts Institute Of Technology Lipid-coated polymer particles for immune stimulation
CN102654505A (zh) * 2012-05-16 2012-09-05 江苏省原子医学研究所 一种检测il-2-hsa的时间分辨荧光免疫分析试剂盒及其检测方法
EP2925297B1 (en) * 2012-11-02 2017-06-21 CyTuVax Composition comprising cytokine macro-aggregates
US9770415B2 (en) * 2012-11-27 2017-09-26 Southwest Research Institute Delivery substrates from aligned polymer biomaterials for tissue repair
CA3191031A1 (en) 2013-09-27 2015-04-02 Massachusetts Institute Of Technology Carrier-free biologically-active protein nanostructures
AU2016256979B2 (en) 2015-05-04 2021-01-28 Genfit Method for preparing transmembrane pH-gradient vesicles
AU2016305087B2 (en) 2015-08-12 2022-01-20 Massachusetts Institute Of Technology Cell surface coupling of nanoparticles
CN109715196A (zh) 2016-06-13 2019-05-03 转矩医疗股份有限公司 用于促进免疫细胞功能的组合物和方法
CA3074826A1 (en) 2017-09-05 2019-03-14 Torque Therapeutics, Inc. Therapeutic protein compositions and methods of making and using the same
US20200078427A1 (en) 2018-09-06 2020-03-12 NuVessl, Inc. Cannabis Sativa Derived Formulation for Transmucosal and Transdermal Delivery
US20200188298A1 (en) 2018-12-14 2020-06-18 NuVessl, Inc. Method For Using Composition With Enhanced Passenger Molecule Loading
US20230096704A1 (en) * 2020-02-05 2023-03-30 University Of Florida Research Foundation, Incorporated Rna-loaded nanoparticles and use thereof for the treatment of cancer
EP4209586B1 (en) * 2020-09-04 2025-10-29 Daegu Gyeongbuk Institute Of Science and Technology Extracellular vesicle expressing cytokine and antibody, method for producing same, and use thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04356421A (ja) * 1991-03-06 1992-12-10 Green Cross Corp:The プロスタグランジン類含有脂肪小体組成物
US6312718B1 (en) * 1996-02-16 2001-11-06 Biomira Usa, Inc. Vaccine for B-cell malignancies

Also Published As

Publication number Publication date
JP2001517693A (ja) 2001-10-09
US6544549B1 (en) 2003-04-08
CA2305533C (en) 2009-12-01
EP1019026A2 (en) 2000-07-19
ATE286717T1 (de) 2005-01-15
WO1999016426A3 (en) 1999-06-17
IN190388B (enExample) 2003-07-26
AU9680098A (en) 1999-04-23
WO1999016426A2 (en) 1999-04-08
AU745000B2 (en) 2002-03-07
CA2305533A1 (en) 1999-04-08
DE69828624D1 (de) 2005-02-17
EP1019026B1 (en) 2005-01-12

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Legal Events

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8327 Change in the person/name/address of the patent owner

Owner name: BIOMIRA INC., EDMONTON, ALBERTA, CA

8364 No opposition during term of opposition